In vitro profiling of endocrine disrupting potency of 2,2′,4,4′-tetrabromodiphenyl ether (BDE47) and related hydroxylated analogs (HO-PBDEs)

► The endocrine effects of BDE47 and related hydroxylated analogues (HO-PBDEs) were studied in vitro. ► BDE47 and its hydroxylated analogues all modulated ER-, TR- and AR-mediated responses. ► Some HO-BDEs were more potent than BDE47.