کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7270253 | 1473237 | 2014 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ovarian hormones and chronic pain: A comprehensive review
ترجمه فارسی عنوان
هورمون های تخمدان و درد مزمن: یک بررسی جامع
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کلمات کلیدی
temporomandibular joint disorder - اختلال مفصلی temporomandibularchronic pain - درد مزمنchronic pelvic pain - درد مزمن لگنMigraine headache - سردرد میگرنیirritable bowel syndrome - سندروم روده تحریک پذیر، کولیت عصبیFibromyalgia - فیبرومیالژیاOvarian hormones - هورمون های تخمدانMenstrual cycle - چرخه قاعدگی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
چکیده انگلیسی
Most chronic noncancer pain (CNCP) conditions are more common in women and have been reported to worsen, particularly during the peak reproductive years. This phenomenon suggests that ovarian hormones might play a role in modulating CNCP pain. To this end, we reviewed human literature aiming to assess the potential role of ovarian hormones in modulating the following CNCP conditions: musculoskeletal pain, migraine headache, temporal mandibular disorder, and pelvic pain. We found 50 relevant clinical studies, the majority of which demonstrated a correlation between hormone changes or treatments and pain intensity, threshold, or symptoms. Taken together, the findings suggest that changes in hormonal levels may well play a role in modulating the severity of CNCP conditions. However, the lack of consistency in study design, methodology, and interpretation of menstrual cycle phases impedes comparison between the studies. Thus, while the literature is highly suggestive of the role of ovarian hormones in modulating CNCP conditions, serious confounds impede a definitive understanding for most conditions except menstrual migraine and endometriosis. It may be that these inconsistencies and the resulting lack of clarity have contributed to the failure of hormonal effects being translated into medical practice for treatment of CNCP conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: PAIN® - Volume 155, Issue 12, December 2014, Pages 2448-2460
Journal: PAIN® - Volume 155, Issue 12, December 2014, Pages 2448-2460
نویسندگان
Samah Hassan, Abi Muere, Gillian Einstein,