کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8652273 | 1573593 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Albumine sérique et maladies cardiovasculaires : une revue approfondie de la littérature
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کلمات کلیدی
Chirurgie cardiovasculaireSerum albumin - آلبومین سرم inflammation - التهاب( توروم) coronary artery disease - بیماری عروق کرونرCoronaropathie - بیماری عروق کرونرcardiovascular disease - بیماری قلب و عروقیMaladies cardiovasculaires - بیماری های قلبی عروقیCardiovascular surgery - جراحی قلب و عروقMalnutrition - سوء تغذیهDénutrition - سوء تغذیهAccident vasculaire cérébral - سکته مغزیStroke - سکته مغزیmodifiable risk factor - فاکتور خطر قابل تغییر استInsuffisance cardiaque - نارسایی قلبheart failure - نارسایی قلبیPronostic - پیش بینیprognosis - پیش شناخت بیماری
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cardiovascular diseases are the leading cause of death worldwide. Conceptually, endothelial dysfunction, inflammatory status and oxidative stress are at the forefront in the onset and development of most cardiovascular diseases, particularly coronary artery disease and heart failure. Serum albumin, the most abundant plasma protein, has many physiological properties, including anti-inflammatory, antioxidant and antiplatelet aggregation activity. It also plays an essential role in the fluid exchange across the capillary membrane. Definite evidence is that hypo-albuminemia is a powerful prognostic marker in the general population as well as in many pathological settings. In the more specific context of cardiovascular diseases, serum albumin is independently associated with the development of a variety of deleterious conditions such as coronary artery disease, heart failure, atrial fibrillation and stroke. Serum albumin has also emerged as a powerful prognostic parameter in patients with coronary artery disease, heart failure, congenital heart disease, infective endocarditis, cardiovascular surgery and stroke, regardless of usual prognostic markers. This prognostic value probably refers mainly to the malnutrition-inflammation syndrome and the severity of comorbidities. Nevertheless, hypo-albuminemia may act as an unknown and modifiable risk factor that contributes to the emergence and the pejorative evolution of cardiovascular diseases, mainly by exacerbation of inflammation, oxidative stress and platelet aggregation, and by pulmonary and myocardial edema. This article provides an overview of the physiological properties of serum albumin, the prevalence, causes, prognostic value and potential contribution to the emergence and aggravation of cardiovascular disease of hypoalbuminemia, as well as its clinical implications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annales de Cardiologie et d'Angéiologie - Volume 67, Issue 2, April 2018, Pages 82-90
Journal: Annales de Cardiologie et d'Angéiologie - Volume 67, Issue 2, April 2018, Pages 82-90
نویسندگان
S. Arques,