کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8886349 | 1627547 | 2018 | 39 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bioaccumulation and effects of titanium dioxide nanoparticles and bulk in the clam Ruditapes philippinarum
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
علوم زمین و سیارات
اقیانوس شناسی
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چکیده انگلیسی
Biochemical and cellular responses to low concentrations of TiO2 nanoparticles (nTiO2, 1 and 10â¯Î¼g/L) and bulk (bTiO2, 10â¯Î¼g/L) were evaluated in gills, digestive gland and haemolymph of the clam Ruditapes philippinarum after1, 3 and 7 days' exposure. At 7 days, titanium content was determined in gills and digestive gland. nTiO2 significantly increased antioxidant enzyme activities in both tissues, and lipid peroxidation in digestive gland at 10â¯Î¼g/L only, and affected glutathione S-transferase activity. Slighter variations were observed in bTiO2-treated clams. A significant Ti bioaccumulation was detected in both gills and digestive gland of 10â¯Î¼g nTiO2/L-exposed clams. In haemolymph, nTiO2 affected total haemocyte count, haemocyte proliferation, haemocyte diameter and volume, and induced DNA damage. Overall, this study demonstrated that TiO2 alters most of the biomarkers measured in clams, although responses were differently modulated depending on tissues and exposure conditions, and indicated that nTiO2 can be accumulated by bivalves, suggesting a potential risk for filter-feeding animals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Marine Environmental Research - Volume 136, May 2018, Pages 179-189
Journal: Marine Environmental Research - Volume 136, May 2018, Pages 179-189
نویسندگان
Ilaria Marisa, Valerio Matozzo, Alessandro Martucci, Erica Franceschinis, Nicola Brianese, Maria Gabriella Marin,