کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9226986 | 1202028 | 2005 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Objective monitoring of nasal patency and nasal physiology in rhinitis
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کلمات کلیدی
SARNARNasal peak inspiratory flowNasal obstruction - انسداد بینیMucociliary clearance - ترخیص موکوسیلیارPar - توسطcomputerized tomography - توموگرافی کامپیوتریRhinomanometry - رینمانومتریAcoustic rhinometry - رینومتری صوتیRhinitis - رینیتPerennial allergic rhinitis - رینیت آلرژیک سالمSeasonal allergic rhinitis - فندق رینیت آلرژیکNasal airflow resistance - مقاومت در برابر جریان هوا بینی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In addition to nasal obstruction, allergic rhinitis is recognized to be associated with impaired mucociliary clearance and altered nasal responsiveness. Measures exist for the monitoring of these aspects of nasal dysfunction. Although measures of mucociliary clearance are simple to perform, they have a poor record of reproducibility. Their incorporation into clinical trials is thus questionable, although positive outcomes from therapeutic intervention have been reported. Measures of nasal responsiveness are at present largely confined to research studies investigating disease mechanisms in allergic and nonallergic rhinitis. The techniques are insufficiently standardized to be applied to multicenter clinical trials but could be used in limited-center studies to gain insight into the regulatory effects of different therapeutic modalities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 115, Issue 3, Supplement, March 2005, Pages S442-S459
Journal: Journal of Allergy and Clinical Immunology - Volume 115, Issue 3, Supplement, March 2005, Pages S442-S459
نویسندگان
Robert A. MD, Ron PhD, DSc, Peter H. BSc (Hons), DM, FRCP, Sverre K. MD, PhD, Alkis MD,