Keywords: ATG; autophagy-related proteins; CMA; chaperone-mediated autophagy; ULK1; Unc-51-like kinase 1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; PE; phosphatidylethanolamine; IFN-γ; interferon-γ; IL-1; interleukin-1; IL-17; inte
مقالات ISI (ترجمه نشده)
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Keywords: Lung adenocarcinoma; Coumarin; Phenylsulfonylfuroxan; Autophagy; Apoptosis; NSCLC; non-small cell lung cancer; LC3; light chain 3; 3-MA; 3-methyladenine; CQ; Chloroquine; TEM; transmission electron microscopy; mTOR; mammalian target of rapamycin; Erk; ext
Keywords: PTZ; pentylenetetrazol; SE; status epilepticus; KD; ketogenic diet; ND; normal control diet; FJB; Fluoro-jade B; MOMP; mitochondrial out-membrane permeabilization; mTOR; mammalian target of rapamycin; RAP; rapamycin; 3-MA; 3-methyladenine; ATG 5; autophag
Keywords: Diabetic cardiomyopathy; Curcumin; Autophagy; Apoptosis; Beclin1; 3-MA; 3-methyladenine; 4E-BP1; 4E-binding protein 1; AMPK; 5â² adenosine monophosphate -activated protein kinase; BH; Bcl-2-homology; CC; AMPK inhibitor compound C; mTOR; mammalian target
Keywords: Harmine; Gastric cancer; Autophagy; Apoptosis; mTOR; Akt; protein kinase B; AMPK; adenosine 5â²-monophosphate-activated protein kinase; BafA1; bafilomycin A1; FBS; fetal bovine serum; HM; harmine; LC3; the light chain 3; 3-MA; 3-methyladenine; MAPK; mito
Keywords: microRNA-124; spinal cord; ischemia-reperfusion; mitophagy; apoptosis; 3-MA; 3-methyladenine; ASPP; apoptosis-stimulating proteins of p53; iASPP; inhibitory member of the apoptosis-stimulating proteins of p53 family; MDI; Motor deficit index; miRNA; micro
Keywords: Suspected drug users; Illicit drugs; Stimulant designer drugs; Biological samples; Seizure data; Mephedrone (4-MMC); 4-methylmetcathinone, 2-(methylamino)-1-(4-methylphenyl)propan-1-one; 3-FA; 3-fluoro-amphetamine, 1-(3-fluorophenyl)propan-2-amine; 4-FA;
Keywords: TNBC; triple negative breast cancer; ROS; reactive oxygen species; H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; MTT; 3-[4,5-dimethyl-2-thiazolyl]-2,5-diphenyl-2H-tetrazolium bromide; CI value; combination index value; DXR; doxorubicin; 3-MA; 3
Keywords: 3-MA; 3-methyladenine; Asc; ascorbate; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BRAF; murine sarcoma viral oncogene homolog B; Cat; catalase; Chk2; checkpoint kinase 2; CQ; chloroquine; Cys-SO3H; cysteine S-sulfate; DHA; dehydroasc
Keywords: HP; Helicobacter pylori; BSA; bovine serum albumin; BiNP; bismuth nanoparticles; MTT; 3-(4,5-dimethylthiazol-2-yl)-diphenyltetrazolium bromide; DMSO; dimethyl sulfoxide; 3-MA; 3-methyladenine; MDC; monodansylcadaverine; EDX; energy dispersive X-ray; NP; n
Keywords: AO; acridine orange; Alexa 488-Ac-LDL; Alexa Fluor 488-acetylated low-density lipoprotein; Baf; bafilomycin A1; B-Fe3O4NPs; bare ferroferric oxide nanoparticles; CRP; C-reactive protein; eNOS; endothelial NO synthase; FBS; fetal bovine serum; FGF-2; fibro
Keywords: 3-MA; 3-methyladenine; Bax; Bcl-2-associated X protein; BBB; Basso-Beattie-Bresnahan; Bcl-2; B-cell lymphoma-2; CD31; platelet endothelial cell adhesion molecule-1; ELISA; enzyme-linked immunosorbent assay; GFAP; glial fibrillary acidic protein; I/R;
Keywords: 3-MA; 3-methyladenine; AFC; 7-amino-4-trifluoromethyl-coumarin; AIF; apoptosis-inducing factor; COX II; cytochrome c oxidase subunit II; CsA; cyclosporin A; Ct; threshold cycle number; Cyt. c; cytochrome c; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; nee
Keywords: 3-MA; 3-methyladenine; ACAT1; Acyl-CoA:cholesterol acyltransferase 1; AD; Alzheimer's disease; Atg; autophagy-related protein; AVs; autophagic vesicles; Aβ; amyloid beta; BCAS; bilateral common carotid artery stenosis; CB2R; cannabinoid receptor 2; CMA
Keywords: 3-MA; 3-methyladenine; 6-OHDA; 6-hydroxydopamine; AD; Alzheimer's disease; AIF; apoptosis inducing factor; ALR; autophagosome-lysosome reformation; ALS; amyotrophic lateral sclerosis; AMD; age- dependent macular degeneration; ApoE; apolipoprotein E; APP
Keywords: HCC; hepatocellular carcinoma; TSN; tumour culture supernatant; 3-MA; 3-methyladenine; CQ; chloroquine; OSM; oncostatin M; MMP9; matrix metalloproteinase-9; Autophagy; Neutrophil; Survival; Pro-tumourigenic properties; Hepatocellular carcinoma;
Keywords: BafA1; bafilomycin A1; CCK-8; cell counting kit-8; CNT; carbon nanotubes; CTRL; vehicle treated control; CQ; chloroquine; DTS; dense tubular system; ER; endoplasmatic reticulum; FESEM; field emission scanning electron microscopy; GFP; green fluorescence p
Keywords: AF; atrial fibrillation; Cx; connexin; DMSO; dimethyl sulfoxide; GFP; green fluorescent protein; gj; junctional conductance; Gj; normalized junctional conductance; Gj,max; maximum junctional conductance; Gj,min; minimum junctional conductance; HEPES; 4-(2
Keywords: 3-MA; 3-methyladenine; STZ; streptozotocin; TBG; tail blood glucose; CHOP; CCAAT-enhancer-binding protein homologous protein; siRNA; small interfering RNA; ER; endoplasmic reticulum; Autophagy; Apoptosis; Endoplasmic reticulum stress; Podocyte;
Keywords: IGF-1; insulin-like growth factor-1; LID; liver IGF-1 deficiency; WT; wild type; FFA; free fatty acid; 3-MA; 3-methyladenine; GH; growth hormone; mTOR; mammalian target of rapamycin; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; P
A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy
Keywords: Akt; protein kinase B; Ambra1; Autophagy And Beclin 1 Regulator 1; AMPK; 5â² AMP-activated protein kinase; Atg; autophagy related proteins; CAMKK; Ca2+/calmodulin-dependent protein kinase kinase; DFCP1; double FYVE-containing protein 1; DPP4; dipeptidyl
Hepatitis B Virus X protein elevates Parkin-mediated mitophagy through Lon Peptidase in starvation
Keywords: HCC; Hepatocellular Carcinoma; HBV; Hepatitis B virus; HBx; Hepatitis B Virus X protein; PINK1; PTEN Induced Putative Kinase 1; UPRmt; Mitochondrial Unfolded-Protein Response; LONP1; Lon Peptidase 1; EBSS; Earle's balance salt solution; LC3; microtubule-a
Physakengose G induces apoptosis via EGFR/mTOR signaling and inhibits autophagic flux in human osteosarcoma cells
Keywords: Physakengose G; Osteosarcoma; Apoptosis; Autophagy; EGFR/mTOR; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; EdU; 5-ethynyl-2â²-deoxyuridine; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; AVOs; acidic vesicular
ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine
Keywords: MEF; mouse embryonic fibroblast; UPR; unfolded protein response; ER; endoplasmic reticulum; DKO; double knock out; ROS; reactive oxygen species; GFP; green fluorescent protein; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2 associated X protein; Bak; Bcl-2 antagoni
Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2- Deoxyglucose; 3-MA; 3-Methyladenine; ACC; Acetyl-CoA Carboxylase; Ad; adenoviruses; AKT; Protein Kinase B, also known as AKT; AMPK; Adenosine 5â²-monophosphate (AMP)-activated protein kinase; AT
Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy
Keywords: TEM; transmission electron microscope; DCFDA; dihydrodichloroï¬uorescein diacetate; MEK; mitogen activated protein kinase kinase; ERK; extracellular signal-regulated kinase; mTOR; mammalian target of rapamycin; ROS; reactive oxygen species; PDX; patient
By Targeting Atg7 MicroRNA-143 Mediates Oxidative Stress-Induced Autophagy of c-Kit+ Mouse Cardiac Progenitor Cells
Keywords: Atg7; autophagy-related gene 7; CPCs; cardiac progenitor cells; GFP; green fluorescent protein; LV; left ventricular; MI; myocardial infarction; 3-MA; 3-methyladenine; mRFP; monomeric red fluorescent protein; SQSTM1; sequestosome 1; IHD; ischemic heart di
Functional polysaccharide Lentinan suppresses human breast cancer growth via inducing autophagy and caspase-7-mediated apoptosis
Keywords: Lentinan; Autophagy; Breast cancer; Apoptosis; Caspase-7; PCD; programmed cell death; SLNT; water-extracted Lentinan; TEM; trsnsmission electron microscopy; NC; negative control; H&E; haematoxylin and eosin; AVi; autophagosome; AVd; autolysosome; 3-MA; 3-
Vanadium(IV)-chlorodipicolinate alleviates hepatic lipid accumulation by inducing autophagy via the LKB1/AMPK signaling pathway in vitro and in vivo
Keywords: 3-MA; 3-methyladenine; ALT; alanine aminotransferase; AMPK; adenosine monophosphate-activated protein kinase; AST; aspartate aminotransferase; BSOV; bis((5-hydroxy-4-oxo-4H-pyran-2-yl)methyl-2-hydroxy-benzoatato) oxovanadium (IV); DMEM; Dulbecco's modifie
Calcimycin induced IL-12 production inhibits intracellular mycobacterial growth by enhancing autophagy
Keywords: M. bovisBCG; Mycobacterium bovis BCG; M. tb; Mycobacterium tuberculosis; TB; Tuberculosis; P2RX7; Purinergic receptor P2X7; Atg; Autophagy-related gene; LC3; Microtubule-associated protein 1A/1B-light chain 3; 3-MA; 3-methyladenine; Baf-A1; Bafilomycin A1
Autophagy in endometriosis: Friend or foe?
Keywords: Autophagy; Endometriosis; Friend; Foe; Mechanism; 3-MA; 3-methyladenine; ERK; extracellular signal-regulated kinase; MIS; Mullerian inhibiting substance; mTOR; Mammalian target of rapamycin; NF-κB; nuclear factor-k-gene binding κ; OH-1; heme oxygenase-1
RIP1K Contributes to Neuronal and Astrocytic Cell Death in Ischemic Stroke via Activating Autophagic-lysosomal Pathway
Keywords: 3-MA; 3-methyladenine; AO; Acridine Orange; DMEM; Dulbecco's Modified Eagle's Medium; GFAP; glial fibrillary acidic protein; HRP; horseradish peroxidase; LC3 II; light chain 3 II; LDH; lactate dehydrogenase; LMP; lysosomal membrane permeability; MAP2; mic
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer
Keywords: Morusin; Paraptosis-like cell death; EOC; VDAC; Mitochondrial Ca2+ overload; Mitochondrial dysfunction; EOC; epithelial ovarian cancer; VDAC; voltage-dependent anion channel; DIDS; 4, 4â²-diisothiocyanostilbene-2, 2â²-disulfonic acid; NAC; N-acetyl-l-cy
Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism
Keywords: Ac; acetylated; ADA; the 3 AKT phosphorylation sites of FOXO1 are mutated; AKT; thymoma viral proto-oncogene; ATG; autophagy-related; AVOs; acidic vesicular organelles; AOI; antioxidant inhibitors; BECN1; beclin 1; BP; blank plasmid; CAT; catalase; CCK-8;
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2
Keywords: Exendin-4; Pancreas; Impaired autophagy; Apoptosis; Ex-4; Exendin-4; GLP-1; glucagon-like peptide 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide; LC3B; light chain 3B; LAMP-2; lysosome associated membrance protein; CatB/L; cathepsin
Posttranslational regulation of CYP2J2 by nitric oxide
Keywords: 3-MA; 3-methyladenine; AA; arachidonic acid; ASC; ascorbate; Bort; bortezomib; BST; biotin-switch technique; Calp; calpeptin; CHX; cycloheximide; Dan; danazol; DMEM; Dulbecco's modified Eagle Medium; DPTA; dipropylenetriamine NONOate; EETs; epoxyeicosatri
Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway
Keywords: IRI; ischemia/reperfusion injury; OGD/R; oxygen-glucosedeprivation/reoxygenation; H2; hydrogen; RAP; rapamycin; 3-MA; 3-methyladenine; MTT; 3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; ROS; reactive oxygen species; MMP; mitochondrial mem
Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo
Keywords: NB; Neuroblastoma; IGF; Insulin and insulin-like growth factors; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; p70S6K; p70 ribosomal protein S6 kinase; 4E-BP1; eukaryotic translat
Hypericin inhibits hepatitis C virus replication via deacetylation and down-regulation of heme oxygenase-1
Keywords: Hepatitis C virus (HCV); Hypericin; Epigenetic; Deacetylation; HCV; Hepatitis C virus; NS5A; non-structure protein 5A; NS3; non-structure protein 3; HO-1; heme oxygenase 1; 5-Aza-dC; 5-aza-2â²-deoxycytidine; DAAs; direct acting antivirals; PCR; polymeras
Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer's disease
Keywords: Autophagy; Oxidative stress; Apoptosis; 3-MA; Aβ1-42;
AIM2 is a potential therapeutic target in human renal carcinoma and suppresses its invasion and metastasis via enhancing autophagy induction
Keywords: AIM2; Absent in melanoma 2; RCC; Renal cell carcinoma; dsDNA; Double-stranded DNA; ASC; Apoptosis-associated speck-like protein containing a caspase recruitment domain; HPV; human papillomavirus; OSCC; squamous cell carcinoma; NSCLC; non-small cell lung c
Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells
Keywords: PF; paeoniflorin; OA; okadaic acid; 3-MA; 3-methyladenine; Rapa; rapamycin; LiCl; lithium chloride; AD; Alzhiemer's disease; CAST; Ac-calpastain; CQ; chloroquine; NFTs; neurofibrillary tangles; CaMKII; calcium/calmodulin protein kinase II; MAP2; microtu
Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells
Keywords: 3-MA; 3-methyladenine; CQ; Chloroquine; Rapa; Rapamycin; EBSS; Dulbecco's Phosphate-Buffered Saline; ATG5; Autophagy-related 5; MAP1LC3/LC3; Microtubule-associated protein 1 light chain 3; mTOR; Mammalian (or mechanistic) Target of Rapamycin; SQSTM1; sequ
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy
Keywords: Astragaloside; Autophagy; Collagen; MAPK; Photoaging; AM; Astragalus Membranaceus; APS; astragalus polysaccharides; ASF; astragalus flavonoids; ASI; astragaloside IV; AST; astragaloside; Col1; collagen-I; CQ; chloroquine; 3-MA; 3-methyladenine; MAPK; mito
Metabolic profiling associated with autophagy of human placenta-derived mesenchymal stem cells by chemical isotope labeling LCâMS
Keywords: MSCs; mesenchymal stem cells; hPMSCs; human placental mesenchymal stem cells; 3-MA; 3-methyladenine; CIL LCâMS; chemical isotope labeling liquid chromatographyâmass spectrometry; Dns; dansylation; DmPA; p-dimethylaminophenacyl; PCA; principal componen
HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer
Keywords: Gold nanoparticle; Trastuzumab resistance; HER2; Gastric cancer; Autophagy; Tmab; trastuzumab; HER2; human epidermal growth factor receptor 2; AuNP; gold nanoparticle; ECD; extracellular domain; ADCC; antibody-dependent cellular cytotoxicity; PTEN; phosph
microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells
Keywords: Imatinib resistance; Autophagy; miR-199a-5p; miR-199b-5p; WNT2; Chronic myeloid leukemia (CML); 3-MA; 3-methyladenine; AVO; acidic vesicular organelle; CML; chronic myeloid leukemia; CQ; chloroquine; DMSO; dimethyl sulfoxide; HRP; horseradish peroxidase;
Hydroxysafflor yellow a protects brain microvascular endothelial cells against oxygen glucose deprivation/reoxygenation injury: Involvement of inhibiting autophagy via class I PI3K/Akt/mTOR signaling pathway
Keywords: 3-MA; 3-methyladenine; A; absorbance; BBB; blood-brain barrier; BCA; bicinchoninic acid; BMECs; brain microvascular endothelial cells; BSA; bovine serum albumin; CNS; central nervous system; DMSO; dimethylsulfoxide; ECL; enhanced chemiluminescence; FBS; f
Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells
Keywords: ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; JNK; c-Jun N-terminal Kinase; NAC; N-acetyl-cysteine; LC3; microtubule-associated protein 1 light chain 3; 3-MA; 3-methyladenine; CCK-8; Cell Counting Kit-8; MMP; mitochondrial membrane
Acrolein induces NLRP3 inflammasome-mediated pyroptosis and suppresses migration via ROS-dependent autophagy in vascular endothelial cells
Keywords: AS; atherosclerosis; CVD; cardiovascular diseases; ROS; reactive oxygen species; HUVECs; human umbilical vein endothelial cells; LPS; lipopolysaccharide; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazo- lium bromide; DMSO; dimethyl sulfoxide; NAC;