Influence of NADPH oxidase inhibition on oxidative stress parameters in rat hearts
Keywords: آپوسیینین; apocynin; endothelin 1; reactive oxygen species; heart
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The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: Role of inflammatory and oxidative brain damage
Keywords: آپوسیینین; Traumatic brain injury; NADPH oxidase; Apocynin; Object recognition task; Oxidative stress
Superoxide Anion Production by NADPH Oxidase Plays a Major Role in Erectile Dysfunction in MiddleâAged Rats: Prevention by Antioxidant Therapy
Keywords: آپوسیینین; Corpus Cavernosum; Oxidative Stress; Apocynin; Antioxidant Therapy; Erectile Dysfunction; Superoxide Dismutase;
Hydrogen peroxide and nitrite reduction in exhaled breath condensate of COPD patients
Keywords: آپوسیینین; Apocynin; COPD; Inflammation
Tamoxifen promotes superoxide production in platelets by activation of PI3-Kinase and NADPH oxidase pathways
Keywords: آپوسیینین; Platelets; Reactive oxygen species; Tamoxifen; Calcium influx; Apocynin; Phosphoinositide-3-kinase
Research ReportAn in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons
Keywords: آپوسیینین; AMPAR; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid receptor; Apo; apocynin; APV; (2R)-amino-5-phosphonovaleric acid; BBB; blood brain barrier; CNQX; 6-cyano-7-nitroquinioxaline-2,3-dione; CrOx; chromium oxalate; DIDS; 4,4-diisothiocyanatostil
Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation
Keywords: آپوسیینین; Traumatic brain injury; Apocynin; Hippocampus; NADPH oxidase; Microglia; Reactive oxygen species; Blood-brain barrier disruption;
Apocynin Improves Erectile Function in Diabetic Rats through Regulation of NADPH Oxidase Expression
Keywords: آپوسیینین; Reactive Oxygen Species; Apocynin; RhoA/ROCK Signaling; Erectile Function; NADPH Oxidase
Role of cerebral endothelial cells in the astrocyte swelling and brain edema associated with acute hepatic encephalopathy
Keywords: آپوسیینین; AA; arachidonic acid; AO; antioxidants; APO; apocynin; AHE; acute hepatic encephalopathy; AQP4; aquaporin-4; CKs; cytokines; CM; conditioned media; CNS; central nervous system; COX2; cyclooxygenase-2; DAPI; 4â², 6-diamidino-2-phenylindole; DHR; dihydrorh
Research ReportInvolvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: Similarity with paraquat neurotoxicity
Keywords: آپوسیینین; Zinc; Paraquat; Oxidative stress; Apocynin; N-Acetyl cysteine; Apoptosis;
Apocynin administration does not improve behavioral and neuropathological deficits in a transgenic mouse model of Alzheimer's disease
Keywords: آپوسیینین; Alzheimer's disease; Apocynin; NADPH oxidase; Amyloid plaques; Oxidative stress;
Apocynin stimulates osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells
Keywords: آپوسیینین; Apocynin; Osteoblastic MC3T3-E1 cells; Differentiation;
Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats
Keywords: آپوسیینین; Antioxidants; Autonomic function; Vitamin C; Apocynin; NADPH oxidase;
Arsenic-induced alteration in intracellular calcium homeostasis induces head kidney macrophage apoptosis involving the activation of calpain-2 and ERK in Clarias batrachus
Keywords: آپوسیینین; MS222; Methanesulfonate salt; RPMI-1640; Roswell Park Memorial Institute culture medium-1640; FBS; Fetal bovine serum; ROS; Reactive oxygen species; MAPK; Mitogen activated protein kinase; ERK; Extracellular signal-regulated kinase; JNK; c-Jun NH2-termina
Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin
Keywords: آپوسیینین; NADPH oxidase; Apocynin; Diabetes; Gluconeogenesis; Kidney; Rabbit;
Synthesis and biological evaluations of novel apocynin analogues
Keywords: آپوسیینین; Apocynin; NADPH oxidase; ROS; Antioxidant
4-Fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis
Keywords: آپوسیینین; Apocynin; Neutrophil; Myeloperoxidase; NADPH oxidase; TNFα; Phagocytosis;
Diapocynin versus apocynin as pretranscriptional inhibitors of NADPH oxidase and cytokine production by peripheral blood mononuclear cells
Keywords: آپوسیینین; Apocynin; Diapocynin; NADPH oxidase; TNF-α; IL-10; gp91phox
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy
Keywords: آپوسیینین; Status epilepticus; Neurodegeneration; Reactive oxygen species; Apocynin; Pilocarpine
Apocynin decreases hydrogen peroxide and nirtate concentrations in exhaled breath in healthy subjects
Keywords: آپوسیینین; Apocynin; NADPH oxidase; ROS; NOS; EBC
Pro-oxidant activity of apocynin radical
Keywords: آپوسیینین; Apocynin; Vanillin; Vanillic acid; Pro-oxidant activity; Glutathione; Quinone; NADPH oxidase
Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia
Keywords: آپوسیینین; Apocynin; Intermittent hypoxia; Spatial learning; NADPH oxidase; Oxidative stress; P22phox; P47phox
The biosynthesis of acetovanillone in tobacco cell-suspension cultures
Keywords: آپوسیینین; Nicotiana tabacum; Solanaceae; Tobacco; Biosynthesis; Acetovanillone; Acetosyringone; Apocynin; Hydroxycinnamoyl-CoA derivatives; Jasmonic acid;
Apocynin restores endothelial dysfunction in streptozotocin diabetic rats through regulation of nitric oxide synthase and NADPH oxidase expressions
Keywords: آپوسیینین; Apocynin; Diabetic complications; Endothelial dysfunction; Nitric oxide synthase; NADPH oxidase
Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow
Keywords: آپوسیینین; NADPH oxidase; Xanthine oxidase; Apocynin; Allopurinol; Pulmonary hypertension
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: The role of reducing oxidative stress in its protective property
Keywords: آپوسیینین; Apocynin; Diabetic nephropathy; NADPH oxidase; Oxidative stress
Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes
Keywords: آپوسیینین; Secretory phospholipase A2-IIA; Astrocytes; NADPH oxidase; MAP kinases; Apocynin; Resveratrol; Epigallocatechin gallate (EGCG)
Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model
Keywords: آپوسیینین; Reactive oxygen species; Abdominal aortic aneurysms; Inducible nitric oxide synthase; NADPH oxidases; Apocynin
Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension
Keywords: آپوسیینین; experimental hypertension; NO synthase; reactive oxygen species; NAD(P)H oxidase; NF-kappa B; apocynin
Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols
Keywords: آپوسیینین; Apocynin; Peroxidase catalysis; Inhibition of NADPH oxidase; Oligophenols;
Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats
Keywords: آپوسیینین; Renin transgenic rats; Hypertension; Angiotensin II; Oxidative stress; Tempol; Apocynin
Involvement of NOX2 in the Development of Behavioral and Pathologic Alterations in Isolated Rats
Keywords: آپوسیینین; Apocynin; GABAergic; interneurons; NADPH oxidase; oxidative stress; parvalbumin;
Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in human tracheal smooth muscle cells
Keywords: آپوسیینین; CSE; cigarette smoke extract; COPD; chronic obstructive pulmonary disease; COX; cyclooxygenase; PG; prostaglandin; AA; arachidonic acid; cPLA2; cytosolic phospholipase A2; HTSMCs; human tracheal smooth muscle cells; DMEM/F-12; Dulbecco's modified Eagle's
How do dietary flavanols improve vascular function? A position paper
Keywords: آپوسیینین; Antioxidants; Apocynin; Catechol-O-methyltransferase; Endothelial; Epicatechin; Flavonoids; NADPH oxidase; Nitric oxide; Oxidative stress; Polyphenol
Protective effects of apocynin against cisplatin-induced oxidative stress and nephrotoxicity
Keywords: آپوسیینین; NADPH oxidase; Superoxide anion (O2−); Cisplatin; Nephrotoxicity; Apocynin
Apocynin improves outcome in experimental stroke with a narrow dose range
Keywords: آپوسیینین; apocynin; superoxide; NADPH oxidase; stroke; brain hemorrhageBBB, blood–brain barrier; EB, Evans Blue; HEt, hydroethidine; NeuN, neuronal nuclei; NOX, NADPH oxidase; PBS, phosphate-buffered saline; ROS, reactive oxygen species; tMCAO, transient middle cer
Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin
Keywords: آپوسیینین; Apocynin; NADPH oxidase inhibitor; Bioavailability; Glycoconjugates; Plasma; Brain
NADPH Oxidase Activation: A Mechanism of Hypertension-Associated Erectile Dysfunction
Keywords: آپوسیینین; Reactive Oxygen Species; Erectile Function; Superoxide; Penis; Angiotensin; Apocynin;
Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages
Keywords: آپوسیینین; Airway inflammation; Arginase; Alveolar macrophages; NADPH oxidase; Reactive oxygen species; Lipopolysacharides; Apocynin; iNOS
The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress
Keywords: آپوسیینین; Apocynin; Glial cells; Nitric oxide; Nuclear factor-kB; Oxidative stress; Catalase; Lipopolysaccharide; NADPH oxidase
(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase
Keywords: آپوسیینین; Apocynin; cGMP; Endothelial; Epicatechin; Flavanol; HUVEC; NADPH oxidase; Nitric oxide; NO imaging;
The reactivity of ortho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin
Keywords: آپوسیینین; Neutrophyl; NADPH oxidase; Myeloperoxidase; Apocynin; Methoxy-catechols; Sulfhydryl residues;
The oxidation of apocynin catalyzed by myeloperoxidase: Proposal for NADPH oxidase inhibition
Keywords: آپوسیینین; Apocynin; Myeloperoxidase; NADPH oxidase; Respiratory burst; Hypochlorous acid; Neutrophil
Cytotoxicity of paraquat in microglial cells: Involvement of PKCδ- and ERK1/2-dependent NADPH oxidase
Keywords: آپوسیینین; Paraquat; NADPH oxidase; Apocynin; Microglia; Cytotoxicity; ROS; Parkinson's disease;
Apocynin but Not l-Arginine Prevents and Reverses Dexamethasone-Induced Hypertension in the Rat
Keywords: آپوسیینین; Apocynin; dexamethasone; hypertension; l-arginine; NAD(P)H oxidase;
Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice
Keywords: آپوسیینین; Apocynin; Zymosan-induced ear swelling; Zymosan-induced arthritis; Cartilage proteoglycan
Oxidant Stress and Blood Pressure Responses to Angiotensin II Administration in Rats Fed Varying Salt Diets
Keywords: آپوسیینین; Hypertension; oxidative stress; angiotensin II; salt intake; apocynin;
Expression of isoforms of NADPH oxidase components in rat pancreatic islets
Keywords: آپوسیینین; Nox; Insulin secretion; RIN cells; Diphenyleneiodonium; Apocynin; Diabetes mellitus
Apocynin protects against global cerebral ischemia–reperfusion-induced oxidative stress and injury in the gerbil hippocampus
Keywords: آپوسیینین; Apocynin; NADPH oxidase; Oxidative stress; Cerebral ischemia–reperfusion; Delayed neuronal death; Glial activation
The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress
Keywords: آپوسیینین; Apocynin; Glial cells; Pentose phosphate pathway; Tricarboxylic acid cycle; Glucose 6-phosphate dehydrogenase; Lactate dehydrogenase; Malonyldialdehyde; Glutathione