Keywords: EAAT; GLAST; GLT-1; Anion conductance; Astrocyte; Tripartite synapse;
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Keywords: 5-HT; 5-hydroxytryptamine; AA; arachidonic acid; ACh; acetylcholine; ACTH; adrenocorticotrophic hormone; AD; Alzheimer's Disease; ADP; adenosine diphosphate; Aβ; amyloid β; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepro
Keywords: ABC; ATP-binding cassette; AJ; adherens junction; Ang; angiopoietin; ApoE; apolipoprotein E; AQP4; aquaporin 4; BBB; blood-brain barrier; cAMP; cyclic AMP; CSF; cerebrospinal fluid; EAAT; excitatory amino acid transporter; EC; endothelial cell; ECF; extra
Keywords: CNS; central nervous system; EAAT; excitatory amino acid transporters; FAS; fetal alcohol syndrome; FASD; fetal alcohol syndrome disorder; GABA; gamma-aminobutyric acid; hpf; hour post fertilization; PNEE; prenatal ethanol exposure; Fetal alcohol syndrome
Keywords: CPP; conditioned place preference; CS; conditioned stimuli; EAAT; excitatory amino acid transporters; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; mPFC; medial prefrontal cortex; VTA; ventral tegmental area; conditioned place preference; glu
Keywords: BIS1; bis-indolylmaleimide 1; CS; calf serum; CNS; central nervous system; MTT; 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium; dbcAMP; dibutyryl cAMP; DMEM; Dulbecco's Modified Eagle Medium; EDTA; ethylenediaminetetra acetic acid; EAAT; excitatory
Selective ion binding and transport by membrane proteins - A computational perspective
Keywords: ABF; Adaptive Biasing Force; ADP; Adenosine Diphosphate; aHL; alpha-Hemolysin; AMBER; Assisted Model Building with Energy Refinement; AMP; Adenosine Monophosphate; AMOEBA; Atomic Multipole Optimized Energetics for Biomolecular Simulation; ATP; Adenosine T
Keywords: cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DPCPX; 8-Cyclopentyl-1,3-dipropylxanthine; EAA; excitatory amino acid; EAAT; excitatory amino acid transporter; NMDA; N-methyl-d-aspartate; TTBS; Tween 20 Tris-Buffered Saline; adenosine;
Keywords: ATSD; anoxic terminal spreading depolarization; CCA; common carotid artery; EAAT; excitatory amino acid transporter; ECA; external carotid artery; ECoG; electrocorticography; ICA; internal carotid artery; MEA; microelectrode arrays; MCA; middle cerebral a
Keywords: AMPA; alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; AMPAR; alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor; CA1; cornu ammonis 1 hippocampal region; cDNA; complementary deoxyribonucleic acid; COX-2; cyclooxygenase 2; EAAT; ex
Keywords: Glutamate; Glutamate transporter 1; Histamine; Excitotoxicity; Ischemia; Neuroprotection; ACSF; artificial cerebrospinal fluid; CNS; central nervous system; DHK; dihydrokainate; EAAT; excitatory amino acid transporter; GABA; gamma-aminobutyric acid; GLAST
Keywords: AQP4; aquaporin 4; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; CD44; cluster of differentiation 44; CSF; cerebrospinal fluid; Cx; connexin; EAAT; excitatory amino acid transporters; EAE; experimental autoimmune encephalomyelitis;
Keywords: Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Keywords: Glutamate; Reversal of Na+-dependent glutamate transporters; Human/rabbit/rat blood platelets; Platelet secretory granules; Rat brain nerve terminals; GABA; gamma-aminobutyric acid; GDH; glutamate dehydrogenase; dl-THA; dl-threo-β-hydroxyaspartate; dl-TB
Keywords: EAAT; excitatory amino acid transporter; ECF; extracellular fluid; GABA; γ-aminobutyric acid; GLN; glutamine; GLU; glutamate; KA; kainic acid; MeAIB; 2-(methylamino)isobutyrate; SNAT; sodium-coupled neutral amino acid transporter; TAU; taurine; Epileptic
AMPA Receptor-Dependent Glutamatergic Signaling is Present in the Carotid Chemoreceptor
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CIH; cyclic intermittent hypoxia; EAAT; excitatory amino acid transporter; H.E.; hematoxylin-eosin staining; NBQX; 2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo[f]quinoaxaline-2,3-dione; NMDA; N-me
Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress
Keywords: Prenatal stress; Depression; SNARE protein; vGluT1; ADHD; attention deficit hyperactivity disorder; CSPα; cysteine-string protein-α; EAAT; excitatory amino acid transporter; EPM; elevated plus maze; FST; forced swimming test; Munc-18; mammalian uncoordi
GABA function may be related to the impairment of learning and memory caused by systemic prenatal hypoxia-ischemia
Keywords: BSA; bovine serum albumin; CA; Ammon's horn; DG; dentate gyrus; EAAT; excitatory amino acid transporter; GABA; γ-aminobutyric acid; GAD; glutamic acid decarboxylase; HI; hypoxia-ischemia; HIE; hypoxic-ischemic encephalopathy; HRP; horseradish peroxidas
Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND
Keywords: Astrocytes; Aging; HIV-associated neurocognitive disorders; Neuroinflammation; ER/Nucleolar/Oxidative stress; Excitotoxicity; Aβ; amyloid beta; AEG-1; astrocyte elevated gene-1; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ARE; a
Propofol Protects Rat Hypoglossal Motoneurons in an In Vitro Model of Excitotoxicity by Boosting GABAergic Inhibition and Reducing Oxidative Stress
Keywords: AIF; apoptosis-inducing factor; APV; (2R)-amino-5-phosphonovaleric acid; CV; coefficient of variation; DAPI; 4â²,6-diamidino-2-phenylindole; DHR 123; dihydrorhodamine 123; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EAAT; excitatory amino acids transporter;
The role of system Xcâ in methamphetamine-induced dopaminergic neurotoxicity in mice
Keywords: Methamphetamine neurotoxicity; System Xcâ; xCT knockout mice; Glutamate-related toxicity; Oxidative damage; Striatum; ANOVA; analysis of variance; CNS; central nervous system; DA; dopamine; DCF; dichlorofluorescin; DCFH-DA; 2â²,7â²-dichlorofluorescin
Astroglial glutamate transporters coordinate excitatory signaling and brain energetics
Keywords: Glutamate transport; GLT-1; GLAST; EAAT; Mitochondria; Glycolysis; GlycogenANT, adenine nucleotide translocase; DL-TBOA, DL-threo-ß-benzyloxyaspartate; EAAT, excitatory amino acid transporter; eGFP, enhanced green fluorescent protein; GABA, γ-aminobutryic
The afferent signaling complex: Regulation of type I spiral ganglion neuron responses in the auditory periphery
Keywords: Cochlea; Inner hair cells; Type I spiral ganglion neurons; Lateral olivocochlear efferents; Ion channels and transporters; Neurotransmitter receptors; Postsynaptic density; Auditory neuropathy and synaptopathy; ABR; auditory brainstem response; ACh; acety
Glycine transporters type 1 inhibitor promotes brain preconditioning against NMDA-induced excitotoxicity
Keywords: Brain preconditioning; Neuroprotection; Neurotransmission; Glycine transporter type 1; ACSF; artificial cerebrospinal fluid; EAAT; excitatory amino-acid transporter; GC-MS; gas chromatography - mass spectrometry; GlyT1; glycine transporters type 1; Gl
Research ReportChanges in VGLUT2 expression and function in pain-related supraspinal regions correlate with the pathogenesis of neuropathic pain in a mouse spared nerve injury model
Keywords: VGLUT; vesicular glutamate transporter; SNI; spared nerve injury; CSB6B; Chicago Sky Blue 6B; EAAT; excitatory amino acid transporter; PAG; periaqueductal gray; mPFC; medial prefrontal cortex; ACSF; artificial cerebrospinal fluid; PB; phosphate-buffer; PB
CDK5 knockdown in astrocytes provide neuroprotection as a trophic source via Rac1
Keywords: CDK5; cyclin-dependent kinase; GLU; glutamate; AD; Alzheimer's disease; DIV; day in vitro; ROS; reactive oxygen species; BDNF; brain-derived neurotrophic factor; ROCK; Rho kinase; LDH; lactate dehydrogenase; G-LISA; GTP enzyme-linked immunosorbent assay;
Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking
Keywords: ACSF; artificial cerebrospinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; DMSO; dimethyl sulfoxide; EAAT; excitatory amino acid transporter; PKA; protein kinase A; PP2A; protein phosphatase 2A; α-Amino-3-hydroxy-5-methy
Pharmacoperones and the calcium sensing receptor: Exogenous and endogenous regulators
Keywords: ADH; autosomal dominant hypocalcemia; CaSR; calcium sensing receptor; xCT; cystine-glutamate transporter; DHPs; dihydropyridines; EAAT; excitatory amino acid transporter; EGFR; endothelial growth factor receptor; ER; endoplasmic reticulum; ERK1/2; extrace
Sarcosine preconditioning induces ischemic tolerance against global cerebral ischemia
Keywords: 4VO; four-vessel occlusion; ACSF; artificial cerebrospinal fluid; AEBSF; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride; ANOVA; one-way analysis of variance; BSA; Bovine serum albumin; EAAT; excitatory amino-acid transporter; GC-MS; gas chromato
Possible roles of glutamate transporter EAAT5 in mouse cone depolarizing bipolar cell light responses
Keywords: ERG; electroretinogram; BC; bipolar cell; EAAT; excitatory amino-acid transporter; GLU; glutamate; LAP4; l-(+)-2-amino-4-phosphonobutyric acid; TBOA; dl-threo-β-benzyloxyaspartic acid; ONL; outer nuclear layer; OPL; outer plexiform layer; INL; inner nucl
Glutamate dysregulation in the trigeminal ganglion: A novel mechanism for peripheral sensitization of the craniofacial region
Keywords: ANOVA; analysis of variance; APV; 2-amino-5-phosphonovalerate; CGRP; calcitonin gene-related peptide; CV; conduction velocity; DMEM; Dulbecco's modified minimum essential medium; DRG; dorsal root ganglion; EAAT; excitatory amino acid transporter; GS; gl
Pharmacological inhibitions of glutamate transporters EAAT1 and EAAT2 compromise glutamate transport in photoreceptor to ON-bipolar cell synapses
Keywords: ERG; electroretinogram; BC; bipolar cell; EAAT; excitatory amino-acid transporter; GLT; glial glutamate transporter; GLU; l-glutamic acid; LAP4; l-(+)-2-amino-4-phosphonobutyric acid; DHK; dihydrokainic acid; TBOA; dl-threo-β-benzyloxyaspartic acid; UCPH
Drosophila melanogaster as a genetic model system to study neurotransmitter transporters
Keywords: 5HT; 5-hydroxytryptamine (serotonin); ACh; acetylcholine; ASD; autism spectrum disorder; ChT; choline transporter; ChAT; choline acetyl transferase; DA; dopamine; Ddc; dopa decarboxylase; EAAT; excitatory amino acid transporter; GABA; gamma amino butyric
Riluzole increases glutamate uptake by cultured C6 astroglial cells
Keywords: ALS; amyotrophic lateral sclerosis; EAAT; excitatory amino acid transporter; PKC; protein kinase C; PI3K; phosphatidylinositol 3-kinase; FGFR1; fibroblast growth factor receptor 1; FRS2α; FGFR substrate 2α; MAPK; mitogen-activated protein kinase; ERK; e
Research reportGlutamate transporter type 3 mediates isoflurane preconditioning-induced acute phase of neuroprotection in mice
Keywords: ERK1/2; extracellular signal-regulated kinase 1/2; EAAT; excitatory amino acid transporter; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK3β; glycogen synthase kinase 3β; MCAO; middle cerebral arterial occlusion; SpO2; pulse oximeter oxygen satura
Effects of preconditioning with normobaric hyperoxia on Na+/Ca2+ exchanger in the rat brain
Keywords: EAAT; excitatory amino acid transporters; HO; normobaric hyperoxia; I-HO; HO in intact animals; I-RA; intact RA; IT; ischemic tolerance; MCAO; middle cerebral artery occlusion; NCX; Na+-Ca2+ exchangers; NDS; neurologic deficit score; NF-κB; nuclear fac
Involvement of pGluR1, EAAT2 and EAAT3 in offspring depression induced by prenatal stress
Keywords: AMPAR; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; BPD; bipolar disorder; CON; control group; EAAT; excitatory amino acid transporter; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; GAPDH; glyceraldeh
Regional regulation of glutamate signaling during cuprizone-induced demyelination in the brain
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BSA; bovine serum albumin; CC; corpus callosum; CNS; central nervous system; EAAT; excitatory amino acid transporter; EAE; experimental allergic encephalomyelitis; ECL; enhanced chemiluminescenc
Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release
Keywords: α7; alpha 7; αBGT; α-bungarotoxin; AA; l-ascorbic acid; ACh; acetylcholine; ANOVA; analysis of variance; BSA; bovine serum albumin; CEF; ceftriaxone; DA; dopamine (3-hydroxytyramine); EAAT; excitatory amino acid transporter; Gluox; glutamate oxidase; M
From Pathophysiology to Novel Antidepressant Drugs: Glial Contributions to the Pathology and Treatment of Mood Disorders
Keywords: Antidepressant; astrocytes; depression; EAAT; glia; prefrontal cortex; stress
Chronic brain ischemia induces the expression of glial glutamate transporter EAAT2 in subcortical white matter
Keywords: APC; adenomatous polyposis coli; CBF; cerebral blood flow; EAAT; excitatory amino acid transporter; GFAP; glial-fibrillary acidic protein; GSTÏ; glutathione-S-transferase pi; LBCCA; ligation of bilateral common carotid arteries; MCAO; middle cerebral art
N-acetylcysteine reverses existing cognitive impairment and increased oxidative stress in glutamate transporter type 3 deficient mice
Keywords: EAAT; excitatory amino acid transporter or glutamate transporter; ELISA; enzyme-linked immunosorbent assay; GSSG; glutathione disulfide; HNE; 4-hydroxy-2-nonenal; NAC; N-acetylcysteine; cognitive functions; glutamate transporter 3; glutathione; mice; oxid
Unique ionotropic receptors for D-aspartate are a target for serotonin-induced synaptic plasticity in Aplysia californica
Keywords: Bis; bisindolylmaleimide; BSC; buccal S cluster; C6; hexamethonium; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione disodium; d-Asp; d-aspartate; DNQX; 6,7-dinitroquinoxaline-2,3-dione disodium; d-TC; tubocurarine; EAAT; excitatory amino acid transporter; l-Gl
Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice
Keywords: NMDA; GFAP; Schizophrenia; EAAT; Glt-1; Auditory evoked potential; Drug abuse; Glutamate;
Dog bites man or man bites dog? The enigma of the amino acid conjugations
Keywords: BA; benzoic acid; PAA; phenylacetic acid; HA; hippuric acid; GLY; glycine; GLN; glutamine; TAU; taurine; GLU; glutamic acid; EAA; excitatory amino acid; IAA; inhibitory amino acid; EAAT; excitatory amino acid transporter; ECF; extracellular fluid; CSF; ce
Overview of glutamatergic neurotransmission in the nervous system
Keywords: Glutamate; NMDA; AMPA; EAAT; Transporter; Metabotropic; Psychiatry
Chronic restraint stress decreases glial fibrillary acidic protein and glutamate transporter in the periaqueductal gray matter
Keywords: BSA; bovine serum albumin; CNS; central nervous system; EAAT; excitatory amino acid transporter; GFAP; glial fibrillary acidic protein; IR; immunoreactivity; LPAG; lateral PAG; PAG; periaqueductal gray matter; PB; phosphate buffer; PLSD; protected least s
Localisation of novel forms of glutamate transporters and the cystine-glutamate antiporter in the choroid plexus: Implications for CSF glutamate homeostasis
Keywords: EAAT; GLAST; GLT1; Glutamate; Transporter, CSF;
A new splice variant of the glutamate-aspartate transporter: Cloning and immunolocalization of GLAST1c in rat, pig and human brains
Keywords: Astrocyte; EAAT; Excitotoxicity; GLAST; Oligodendrocyte;
Mitochondrial dysfunction in ALS
Keywords: AEOL-10150; manganese [III] tetrakis[N-Nâ²-diethylimidazolium-2-yl]porphyrin; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propinate; ALS; amyotrophic lateral sclerosis; CCS; copper chaperone for superoxide dismutase; DMPO; 3,4-dihydro-2,3-dimethyl-2H-p