Keywords: تخریب ER-Associated; ABA; abscisic acid; ABI; ABA-insensitive; AIM/LIR; ATG8-interacting motif/LC3-interacting region; AREB/ABFs; ABRE-binding protein/ABRE-binding factor; ARM; armadillo repeat; Atg8; autophagy-related 8; BAG6; BCL-2 associated athanogene 6; BiPs; lumenal bin
مقالات ISI تخریب ER-Associated (ترجمه نشده)
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Keywords: تخریب ER-Associated; ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
Keywords: تخریب ER-Associated; Proteotoxic stress; Secretory proteins; Acute-phase proteins; Acute-phase response; ER folding machinery; ER stress response; ER-associated degradation; Autophagy; Alpha1-antitrypsin deficiency; Hepatitis B infection; Fibrinogen storage disease;
Keywords: تخریب ER-Associated; AMPK; 5â² adenosine monophosphate-activated protein kinase; AT; adipose tissue; BECN1; beclin 1; Bcl-2; B-cell lymphoma 2; Bim; Bcl-2-like protein 11 (BCL2L11); BMI; body mass index; CAD; coronary artery disease; CCS; Canadian Cardiovascular Society; CHO
Keywords: تخریب ER-Associated; Traumatic brain injury; Chronic traumatic encephalopathy; Tauopathy; Concussion; Repetitive head injury; 2-AG; 2-arachidonoylglycerol; 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; Ach; acetylcholine; AChEI; acetylcholine esterase inhibitor; AD; Alzheim
Keywords: تخریب ER-Associated; CE; cholesteryl ester; CIDE; cell death-inducing DFFA-like effector; ER; endoplasmic reticulum; ERAD; ER-associated degradation; FC; free cholesterol; HSL; hormone sensitive lipase; LD; lipid droplet; MOM; mitochondrial outer membrane; SNARE; soluble NSF
Keywords: تخریب ER-Associated; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; LB; Lewy bodies; αSyn; αSynuclein; ER; endoplasmic reticulum; ERAD; ER-Associated Degradation; PINK1; PTEN-induced putative kinase 1; ATP13A2; lysosomal P-type transport ATPase; LRRK2; leuci
Keywords: تخریب ER-Associated; ATF4; activating transcription factor-4; ATF6α; activating transcription factor-6α; EB1; end binding protein-1; EDEM; ER degradation-enhancing α-like protein; ER; endoplasmic reticulum; ERAD; ER-associated degradation; GCN2; general control non-derepre
Keywords: تخریب ER-Associated; AA; ascorbic acid; DHA; dehydroascorbic acid; ER; endoplasmic reticulum; ERAD; ER-associated degradation; Gpx; glutathione peroxidase; GR; glutathione reductase; H6PD; hexose-6-phosphate dehydrogenase; Nox; NADPH oxidase; PDI; protein disulfide isomerase;
Keywords: تخریب ER-Associated; ASK1; apoptosis signal-regulating kinase; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; ATF6; activating transcription factor 6; Atg12; autophagy-related gene 12; C9ORF72; chromosome 9 open reading frame 72; CHIP; carbo
Keywords: تخریب ER-Associated; GJIC; gap junctional intercellular communication; Cx; connexin; Cx43; connexin43; ER; endoplasmic reticulum; ERAD; ER-associated degradation; UbL; ubiquitin-like domain; UBA; ubiquitin-associated domain; AGJ; annular gap junctions; CME; clathrin-mediated
Keywords: تخریب ER-Associated; FACS; fluorescence activated cell sorting; MHCI; MHC class I molecules; MHCII; MHC class II molecules; APC; antigen-presenting cells; DC; dendritic cells; TCR; T cell receptor; MVB; multi-vesicular body; ILV; intraluminal vesicles; MARCH; membrane-associa
Keywords: تخریب ER-Associated; ER; endoplasmic reticulum; UPR; unfolded protein response; AD; Alzheimer's disease; APP; amyloid precursor protein; GRP78/BiP; chaperone glucose-regulated protein 78; PERK; protein kinase RNA (PKR)-like ER kinase; ATF6; activating transcription factor 6;
Keywords: تخریب ER-Associated; ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
Keywords: تخریب ER-Associated; Misfolded multi-trans membranes; Yeast prion; Heat shock response; GET complex; ER; endoplasmic reticulum; MTM; multi-transmembrane; UPR; unfolded protein response; ERAD; ER-associated degradation; TMD; transmembrane domain; GET; guided entry of tail-anch
The reductase TMX1 contributes to ERAD by preferentially acting on membrane-associated folding-defective polypeptides
Keywords: تخریب ER-Associated; Endoplasmic reticulum; ER-Associated degradation; Oxido-reductase; Protein folding and quality control; TMX1; Ubiquitin proteasome system;
Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase
Keywords: تخریب ER-Associated; Cholesterol; Endoplasmic reticulum (ER);; ER-associated degradation; Ubiquitin; Proteasome; Vitamin K; Prenyltransferase; Isoprenoid; Golgi;
ER stress and cancer: The FOXO forkhead transcription factor link
Keywords: تخریب ER-Associated; Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating
Amyloid-beta Degradation and Neuroprotection of Dauricine Mediated by Unfolded Protein Response in a Caenorhabditis elegans Model of Alzheimer's disease
Keywords: تخریب ER-Associated; dauricine; unfolded protein response; ER-associated degradation; Aβ; Alzheimer's disease;
Mitochondrial function requires NGLY1
Keywords: تخریب ER-Associated; C. elegans; Caenorhabditis elegans; CDG; congenital disorders of glycosylation; ER; endoplasmic reticulum; ERAD; ER-associated degradation; ERAF; ER-associated folding; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; FCL; fibroblast cell line
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor
Keywords: تخریب ER-Associated; Nrf1; Topovectorial regulation; Regulated juxtamembrane proteolysis; Ubiquitination; Topobiology; Ubiquitin-like (UBL) domain; Membrane cholesterol-recognized sensor; AD1; acidic domain 1; CRAC; cholesterol-recognition amino acid consensus motif; ER; endo
Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits
Keywords: تخریب ER-Associated; Nrf1; DDI-1/2; p97; Proteoform; Proteasome; Post-Translational Modification; Proteolysis; ER Stress; Hrd1; BTZ; bortezomib; CNC; cap 'n' collar; CHX; cycloheximide; DDI-1; DNA-damage inducible protein homolog 1; Epox; expoxomicin; ER; endoplasmic reticulu
Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia
Keywords: تخریب ER-Associated; B-ALL; B acute lymphoblastic leukemia; ER; endoplasmic reticulum; UPR; unfolded protein response; ERAD; ER-associated degradation; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HNA; 2-hydroxy-1-naphthaldehyde; PI; propidium iodide; PE
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
Keywords: تخریب ER-Associated; aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Keywords: تخریب ER-Associated; CHC; clathrin heavy chain; CHX; cycloheximide; DN; dominant negative; EEA1; early endosome antigen 1; ERAD; ER-associated degradation; ESCRT; endosomal sorting complex required for transport; Hrg; heregulin; ILVs; intra luminal vesicles; LAMP1; lysosome-a
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Keywords: تخریب ER-Associated; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;
Inactive rhomboid proteins: New mechanisms with implications in health and disease
Keywords: تخریب ER-Associated; ADAM17; a disintegrin and metalloproteinase 17; COG; conserved oligomeric Golgi; Der1; degradation in the ER 1; Dfm1; Der1-like family member 1; DKO; double knockout; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; ERAD; ER-associated d
Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells
Keywords: تخریب ER-Associated; ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK8; cell counting kit-8; CHOP; C/EBP homologous protein; DMSO; dimethylsulfoxide; eIF2α; eukaryotic translational initiation factor 2α; ERAD; ER-associated degradation; ER; endoplasmi
Research ArticleHeat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway
Keywords: تخریب ER-Associated; ATF6; activating transcription factor-6; CHX; cycloheximide; eIF2α; phospho-eukaryotic initiation factor 2α; ER; endoplasmic reticulum; ERAD; ER-associated degradation; IRE1α; inositol-requiring protein-1α; MEF; mouse embryonic fibroblast; PDI; protei
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
Keywords: تخریب ER-Associated; 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex
Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I
Keywords: تخریب ER-Associated; ER-associated degradation; E3 ubiquitin ligase; Human cytomegalovirus; Viral immune evasion; TRC8; TMEM129; HRD1;
Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum
Keywords: تخریب ER-Associated; ARMR; autosomal recessive mental retardation; CDG; congenital disorders of glycosylation; ERAD; ER-associated degradation; IEF; isoelectric focusing; LLO; lipid linked oligosaccharide; OST; oligosaccharyltransferase; RAMP; ribosome associated membrane pro
Effects of N-glycan precursor length diversity on quality control of protein folding and on protein glycosylation
Keywords: تخریب ER-Associated; CPY; Saccharomyces carboxypeptidase Y; CPY*; misfolded CPY mutant; N-glycan; Asn-linked glycan; PPI; peptidylprolyl isomerase; PDI; protein disulfide isomerase; QC; quality control; UGGT; UDP-glucose:glucosyltransferase; Endoplasmic reticulum; ER-associat
Mechanisms of p53 degradation
Keywords: تخریب ER-Associated; ATM; ataxia telangiectasia mutated; CHIP; C-terminus of HSP70-interacting protein; CBP; CREB binding protein; COP1; constitutively photo-morphogenic 1; DDB1; DNA damage binding protein 1; DHFR; dihydrofolate reductase; DUB; de-ubiquitinating enzyme; E1; u
Candida albicans autophagy, no longer a bystander: Its role in tolerance to ER stress-related antifungal drugs
Keywords: تخریب ER-Associated; ER; endoplasmic reticulum; UPR; unfolded protein response; ATG; auophagy-related; MM-N; nitrogen source-depleted minimum medium; Cvt; cytosol-to-vacuole; TEM; transmission electron microscopy; PM; plasma membrane; cER; cytoplasmic ER; AP; autophagosome; E
Organelle communication: Signaling crossroads between homeostasis and disease
Keywords: تخریب ER-Associated; Organelles; Endoplasmic reticulum; Mitochondria; Calcium signaling; BNIP1; BCL2/adenovirus E1B interacting protein 1; Ca2+; calcium; CERT; ceramide transfer protein; CMT2A; Charcot-Marie-Tooth type 2A; ÎÏmt; mitochondrial transmembrane potential; Dr
A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib
Keywords: تخریب ER-Associated; ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan
Should I stay or should I go: VCP/p97-mediated chromatin extraction in the DNA damage response
Keywords: تخریب ER-Associated; CPDs; Cyclobutane pyrimidine dimers; DSBs; DNA double-strand breaks; ER; endoplasmic reticulum; ERAD; ER-associated degradation; HR; homologous recombination; 6-4PPs; pyrimidine-pyrimidone [6-4] photoproducts; IR; ionizing radiation; UBD; ubiquitin-bindin
Role of the ubiquitin-proteasome system in brain ischemia: Friend or foe?
Keywords: تخریب ER-Associated; 3-MA; 3-methyladenine; 15d-PHJ2; 15-deoxy-Î12,14-prostaglandin J2; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid; AMPAR; AMPA receptors; APC/C; anaphase-promoting complex/cyclosome; APV; D-aminophosphonovalerate; ATF4; activating transcri
Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes
Keywords: تخریب ER-Associated; ATF; activating transcription factor; Ad-calu; adenovirus containing mouse calumenin 1 cDNA; Ad-lacZ; adenovirus containing lacZ gene; CHOP; C/EBP-homologous protein; ERAD; ER-associated degradation; eIF2; eukaryotic initiation factor 2; ERp57; the thiol
Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells
Keywords: تخریب ER-Associated; CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei
Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic à cell exhaustion
Keywords: تخریب ER-Associated; Ins2; Insulin 2 protein; ER; endoplasmic reticulum; ASK1; apoptosis signal-regulating kinase 1; UPR; unfolded protein response; PERK; protein kinase RNA-like ER kinase; ATF6; activating transcription factor 6; IRE1; inositol-requiring enzyme 1; ERAD; ER-a
Unglycosylated clusterin variant accumulates in the endoplasmic reticulum and induces cytotoxicity
Keywords: تخریب ER-Associated; Clusterin; ER stress; N-glycosylation; ER-associated degradation; Protein folding;
Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response
Keywords: تخریب ER-Associated; NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro
The degradation of apolipoprotein B100: Multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways
Keywords: تخریب ER-Associated; VLDL; Apolipoprotein B; Autophagy; ER-associated degradation; Liver; Triglyceride
A plant peptide: N-glycanase orthologue facilitates glycoprotein ER-associated degradation in yeast
Keywords: تخریب ER-Associated; PNGase; peptide:N-glycanase; ERAD; ER-associated degradation; TG and TGase; transglutaminase; RTAâ; ricin A chain non-toxic mutant; RTL; RTAâ-transmembrane-Leu2; SC; synthetic complete; endo H; endoglycosidase H; Peptide:N-glycanase; ER-associated deg
Redox signaling loops in the unfolded protein response
Keywords: تخریب ER-Associated; AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr
Serial passage of a street rabies virus in mouse neuroblastoma cells resulted in attenuation: Potential role of the additional N-glycosylation of a viral glycoprotein in the reduced pathogenicity of street rabies virus
Keywords: تخریب ER-Associated; BBB; blood-brain barrier; CNS; central nervous system; CVS; challenge virus standard; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; ER; endoplasmic reticulum; ERAD; ER-associated degradation; FCS; fetal calf serum; FF
ER-stress-inducible Herp, facilitates the degradation of immature nicastrin
Keywords: تخریب ER-Associated; Aβ; amyloid β-protein; AD; Alzheimer's disease; APP; β-amyloid precursor protein; ER; endoplasmic reticulum; ERAD; ER-associated degradation; γ-secretase; Presenilin; Nicastrin; E3 ubiquitin ligase;
Orexin neurons in hypothalamic slice cultures are vulnerable to endoplasmic reticulum stress
Keywords: تخریب ER-Associated; hypocretin; neuropeptide turnover; ER-associated degradation; cycloheximide; tauroursodeoxycholic acid; ATF6; activating transcription factor 6; Bip; immunoglobulin G heavy chain-binding protein; CGRP; calcitonin gene-related peptide; CHOP; C/EBP-homologo