دانلود مقالات ISI درباره Erad + ترجمه فارسی

The Arabidopsis endoplasmic reticulum associated degradation pathways are involved in the regulation of heat stress response

Keywords: CER9; HRD1; ERAD; Heat stress response; Cytosolic protein response; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Proteasomal degradation of T. gondii ROP18 requires Derlin2

Keywords: T. gondii; ROP18; Derlin2; ERAD; Degradation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

UBX domain-containing proteins are involved in lipid homeostasis and stress responses in Pichia pastoris

Keywords: ALA; α-linolenic acid; CHX; cycloheximide; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated protein degradation; FDA; fluorescein diacetate; GO; gene ontology; KEGG; Kyoto Encyclopedia of

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewRare ER protein misfolding-mistrafficking disorders: Therapeutic developments

Keywords: Mutations; Misfolding; Trafficking; ERAD;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewLatest emerging functions of SPP/SPPL intramembrane proteases

Keywords: Intramembrane proteolysis; Signal peptide peptidase; SPPL proteases; ERAD; Proteostasis; Ectodomain shedding;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia

Keywords: B-ALL; B acute lymphoblastic leukemia; ER; endoplasmic reticulum; UPR; unfolded protein response; ERAD; ER-associated degradation; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HNA; 2-hydroxy-1-naphthaldehyde; PI; propidium iodide; PE

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular cloning and characterization of unfolded protein response genes from large yellow croaker (Larimichthys crocea) and their expression in response to dietary fatty acids

Keywords: ATF6; activating transcription factor-6; ATF4; activating transcription factor 4; BiP/GRP78; immunoglobulin heavy chain binding protein/glucose-regulated protein 78; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; ERAD; ER-associated protein de

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum

Keywords: aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Ubiquitin-proteasome system and ER stress in the retina of diabetic rats

Keywords: Diabetic retinopathy; UCHL1; ERAD; Apoptosis; Autophagy; 4-PBA;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear

Keywords: DUB; Deubiquitinase; ERAD; endoplasmic-reticulum associated degradation; ESI; electrospray ionization; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; ITC; isothermal titration calorimetry; ML; maximum-likelihood; RING; really-interesting new g

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Structure and functions of the chaperone-like p97/CDC48 in plants

Keywords: ADIN; antibody-dependent intracellular neutralization; ARF; ADP ribosylation factor; AAA + ATPase; ATPase associated with diverse cellular activities; CDC48; cell division cycle 48; CAD; chromatin associated degradation; ER; endoplasmic reticulum; ERAD;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

ErbB3 interacts with Hrs and is sorted to lysosomes for degradation

Keywords: CHC; clathrin heavy chain; CHX; cycloheximide; DN; dominant negative; EEA1; early endosome antigen 1; ERAD; ER-associated degradation; ESCRT; endosomal sorting complex required for transport; Hrg; heregulin; ILVs; intra luminal vesicles; LAMP1; lysosome-a

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?

Keywords: Intramembrane proteolysis; Signal peptide peptidase; SPPL proteases; ERAD; γ-Secretase; Autoimmunity;

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant

Keywords: Proteostasis; Unfolded protein response; Proteasome; Hormesis; Caenorhabditis elegans; ABU; activated in blocked unfolded protein response; ANOVA; analysis of variance; ATF-6; activating transcription factor 6; BiP; immunoglobulin binding protein; C. ele

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2

Keywords: ER stress; UPR; ERAD; 4-Phenylbutyric acid; TGFBIp; GCD2; Corneal fibroblasts; 4-PBA; Sodium 4-phenylbutyric acid; ATF6; Activating transcription factor 6; BiP; Binding immunoglobulin protein; CHOP; C/EBP homologous protein; ER; Endoplasmic reticulum; ERA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages

Keywords: Atg; autophagy-related proteins; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; ERAD; ER-associated protein degradation; FBS; fetal bovine serum; Fisher LSD; Fisher's least significant different test; GS; gl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway

Keywords: NGLY1; N-glycanase; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated degradation; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; TSA; thermal shift assay; DSF; differential scanning fluorimetry; Drug discovery; N-g

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A prominent role of PDIA6 in processing of misfolded proinsulin

Keywords: Proinsulin; PDI; Chaperones; Protein folding; Disulphide bonds; ERAD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Yeast membrane proteomics using leucine metabolic labelling: Bioinformatic data processing and exemplary application to the ER-intramembrane protease Ypf1

Keywords: d3-leucine; trideuterated leucine; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated degradation; LC-MS; liquid chromatography-mass spectrometry; PSM; peptide-to-spectrum matches; SILAC; stable isotope labelling by amino acids in cell cu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inactive rhomboid proteins: New mechanisms with implications in health and disease

Keywords: ADAM17; a disintegrin and metalloproteinase 17; COG; conserved oligomeric Golgi; Der1; degradation in the ER 1; Dfm1; Der1-like family member 1; DKO; double knockout; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; ERAD; ER-associated d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair

Keywords: Gap junctions; Connexin43; Wound repair; Phosphorylation; Src; Protein kinase C; Mitogen-activated protein kinase; Da; daltons; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cx43; Connexin 43; SDS; sodium dodecyl sulfate; PAG

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

Keywords: AKAP; A-kinase anchor protein; ALS; Amyotrophic Lateral Sclerosis; CERT; ceramide transfer protein; ER; endoplasmic reticulum; ERAD; ER-associated destruction; FFAT; two phenylalanines in an acidic tract; MSP; major sperm protein; ORP; OSBP-related protei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells

Keywords: ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK8; cell counting kit-8; CHOP; C/EBP homologous protein; DMSO; dimethylsulfoxide; eIF2α; eukaryotic translational initiation factor 2α; ERAD; ER-associated degradation; ER; endoplasmi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleHeat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway

Keywords: ATF6; activating transcription factor-6; CHX; cycloheximide; eIF2α; phospho-eukaryotic initiation factor 2α; ER; endoplasmic reticulum; ERAD; ER-associated degradation; IRE1α; inositol-requiring protein-1α; MEF; mouse embryonic fibroblast; PDI; protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants

Keywords: AAA; ATPases Associated with various cellular Activities; APEM; Aberrant PEroxisome Morphology; EosFP; Eos Fluorescent protein; ERAD; ER Associated Decay; GET; Guided Entry of TA proteins; pER; peroxisomal ER subdomain; PEX; abbreviation for Peroxin, a pr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer

Keywords: AMSH; associated molecule with the SH3 domain of STAM (signal transducing adaptor molecule); ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; CIP75; Cx43-interacting protein of 75 kD; CIP85; Cx43-interacting protein of 85 kDa; Cx; connex

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Pro-inflammatory cytokines enhance ERAD and ATF6α pathway activity in salivary glands of Sjögren's syndrome patients

Keywords: Sjögren's syndrome; Salivary glands; Endoplasmic reticulum stress; UPR; ERAD; Cytokines;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells

Keywords: 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response

Keywords: Ad-CCN1-4; Ad5-CMV-CCN1-4; Ad-Luc; Ad5-CMV-Luc; ATF6; activating transcription factor 6; β-Gal; β-galactosidase; BDL; bile duct ligation; ECM; extracellular matrix; ER; endoplasmic reticulum; ERAD; ER-associated protein degradation; h; human; HSC; h

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Role of AAA+-proteins in peroxisome biogenesis and function

Keywords: AAA+;  extended ATPases associated with various cellular activities; ATAD1; ATPase family AAA domain-containing protein 1; ERAD; endoplasmic reticulum associated degradation; Msp1p; mitochondrial sorting of proteins 1; NSF; N-ethylmaleimide-sensitive fac

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization, prediction and evolution of plant peroxisomal targeting signals type 1 (PTS1s)

Keywords: AAC; amino acid content; AGT; alanine-glyoxylate aminotransferase; BD; binding domain; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum-associated decay; IAA; indole-3-acetic acid; IBA; indole-3-butyric acid; PEG; polyethylene glycol; PEX; peroxin;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK)

Keywords: ERAD; drGFP; Dislocation/retrotranslocation; Hrd1; Sel1L; p97/VCP;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Compound heterozygous protein C deficiency in a family with venous thrombosis: Identification and in vitro study of p.Asp297His and p.Val420Leu mutations

Keywords: PCD; hereditary protein C deficiency; VTE; venous thromboembolism; DVT; deep vein thrombosis; PC; protein C; ERAD; ER associated degradation; PROC; protein C gene; APC; activated PC; LMWH; low molecular weight heparin; UFH; unfractionated heparin; Protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum

Keywords: ARMR; autosomal recessive mental retardation; CDG; congenital disorders of glycosylation; ERAD; ER-associated degradation; IEF; isoelectric focusing; LLO; lipid linked oligosaccharide; OST; oligosaccharyltransferase; RAMP; ribosome associated membrane pro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Engineered tobacco etch virus (TEV) protease active in the secretory pathway of mammalian cells

Keywords: TEV protease; Sec-TEV; Glycosylation; ER; ERAD; Secretory pathway;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Levels of metacaspase1 and chaperones related to protein quality control in alcoholic and nonalcoholic steatohepatitis

Keywords: Protein quality control; Alcoholic steatohepatitis; Nonalcoholic steatohepatitis; Mca1; Hsp104; Hsp40; Ydj1; Ssa1; VCP/p97; p62; ERAD; IPOD; JUNQ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The role of AGR2 and AGR3 in cancer: Similar but not identical

Keywords: AGR2; AGR3; PDI family; Cancer; AA; amino acids; ALS; familial amyotrophic lateral sclerosis; AGR; anterior gradient; AhR; aryl hydrocarbon receptor; AR; androgen receptor; CAPN8; calpain 8; CAPN9; calpain 9; CDDP; cisplatin; CFTR; cystic fibrosis transme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of p53 degradation

Keywords: ATM; ataxia telangiectasia mutated; CHIP; C-terminus of HSP70-interacting protein; CBP; CREB binding protein; COP1; constitutively photo-morphogenic 1; DDB1; DNA damage binding protein 1; DHFR; dihydrofolate reductase; DUB; de-ubiquitinating enzyme; E1; u

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Glycan regulation of ER-associated degradation through compartmentalization

Keywords: Bap31; B-cell receptor associated protein 31; CNX; calnexin; CRT; calreticulin; ER; Endoplasmic reticulum; ERAD; ER associated degradation; RER; rough ER; ERESs; ER exit sites; ERGIC; ER to Golgi intermediate compartment; ERManI; α1,2 ER mannosidase 1; E

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Tunicamycin-induced unfolded protein response in the developing mouse brain

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; CGNs; cerebellar granule neurons; DAB; 3,3′-diaminobenzidine; DAPI; 4,6-diamidino-phenylindole; DCN; deep cerebellar nucleus; DG; dentate gyrus; DIV; days in vitro; EGL; external germinal laye

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

Keywords: 3-BrPA; 3 bromopyruvate; AOP; adverse outcome pathway; ARF4; ADP-ribosylation factor 4; BFA; brefeldin A; BT; 1,2,4-benzenetriol; CML; chronic myeloid leukemia; COSMID; CRISPR off-target sites with mismatches, insertions, and deletions; CRISPR-Cas9; clust

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Candida albicans autophagy, no longer a bystander: Its role in tolerance to ER stress-related antifungal drugs

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; ATG; auophagy-related; MM-N; nitrogen source-depleted minimum medium; Cvt; cytosol-to-vacuole; TEM; transmission electron microscopy; PM; plasma membrane; cER; cytoplasmic ER; AP; autophagosome; E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

Keywords: HGF; VEGF; ERAD; PI3 kinase; AKT; MEK; IRE1; XBP1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Review/N-glycans: The making of a varied toolbox

Keywords: ALG; asparagine-linked glycosylation; UDP-Glc/Gal; TRANSPORTER; BRI1; brassinosteroid insensitive 1; CGL1; complex glycan 1; EFR; EF-Tu receptor; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated degradation; FLS2; flagellin sensing 2; GCS

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2015 سفارش ترجمه

Organelle communication: Signaling crossroads between homeostasis and disease

Keywords: Organelles; Endoplasmic reticulum; Mitochondria; Calcium signaling; BNIP1; BCL2/adenovirus E1B interacting protein 1; Ca2+; calcium; CERT; ceramide transfer protein; CMT2A; Charcot-Marie-Tooth type 2A; Δψmt; mitochondrial transmembrane potential; Dr

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Ubiquitin in the peroxisomal protein import pathway

Keywords: Ubiquitination; Peroxisome; PEX5; Thioester; Protein trafficking; AAA; ATPases associated with diverse cellular activities; DTM; docking/translocation module; DUBs; deubiquitinating enzymes; E1; ubiquitin-activating enzyme; E2; ubiquitin-conjugating enzym

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Impaired trafficking of the very low density lipoprotein receptor caused by missense mutations associated with dysequilibrium syndrome

Keywords: VLDLR; Dysequilibrium syndrome; ERAD; Protein misfolding; Reelin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Using pharmacological chaperones to restore proteostasis

Keywords: NN-DNJ (PubChem CID: 501640); E4031 (PubChem CID: 3185); Nicotine (PubChem CID: 89594); GABA (PubChem CID: 119); SR121463 (PubChem CID: 9810773); Naltrexone (PubChem CID: 5360515); Pharmacological chaperone; Proteostasis; Chaperone; ERAD; Protein misfoldi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه