دانلود مقالات ISI درباره Ic50 + ترجمه فارسی

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Keywords: Quinoxaline; Pim-1; Kinase inhibitor; Anticancer targeted therapy; IC50; 50% inhibitory concentration; SAR; structure-activity relationships; Pim; proviral integration site of Moloney murine leukemia virus; CML; chronic myeloid leukemia; DYRK1A; dual spec

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Redox-stimuli-responsive drug delivery systems with supramolecular ferrocenyl-containing polymers for controlled release

Keywords: A549; A549 lung cancer cells; AAO; anodized alumina substrates; Ad; adamantane; ALMA; allyl methacrylate; ATRP; atom transfer radical polymerization; AuNPs; gold nanoparticles; CAC; critical aggregation concentration; CB[7]; cucurbituril; β-CD; β-cyclod

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Paraptosis in human glioblastoma cell line induced by curcumin

Keywords: Cell Death; Paraptosis; Curcumin; Endoplasmic Reticulum Stress Response; miRNAs; AKT; Serine-threonine kinase; ATF6; Activating transcription factor 6; BCL2; B- Cell lymphoma 2; BIP; Immunoglobulin-heavy-chain binding protein; CHOP; C/EBPhomologous protei

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability

Keywords: Stapled peptides; Protein-protein interactions; Trypanothione reductase; Leishmania infantum; Cell-penetrating peptides; CD; circular dichroism; CPP; cell-penetrating peptide; ELISA; Enzyme-Linked ImmunoSorbent Assay; FCS; fetal calf serum; FITC; fluoresc

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Gynosaponin TN-1 producing from the enzymatic conversion of gypenoside XLVI by naringinase and its cytotoxicity on hepatoma cell lines

Keywords: Gypenoside XLVI; Gynosaponin TN-1; Enzymatic conversion; Naringinase; Biotransformation; Hepatoma cell lines; ANOVA; analysis of variance; AO; acridine orange; DMSO; Dimethyl sulfoxide; EB; ethidium bromide; FBS; Fetal bovine serum; G. pentaphyllum; Gynos

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Wnt/β-catenin signaling pathway is involved in regulating the migration by an effective natural compound brucine in LoVo cells

Keywords: Brucine; Colorectal cancer; Migration; Wnt/β-catenin; Signaling pathway; DMEM; Dulbecco's modified Eagle's medium; FBS; Fetal bovine serum; MTT; 3-(4, 5-Dimethylthiazol-2-yl)-2.5-diphenyl-2H-tetrazolium bromide; DMSO; Dimethyl sulfoxide; IC50; 50%-growth

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

Keywords: Anti-Influenza; PA-PB1; RdRp; Amino acid coupling; SPPS; Diphenyl-pyridine; AcOEt; Ethyl acetate; CC50; Half maximal cytotoxic concentration; cRNA; complementar RNA; DCM; dichloromethane; DDQ; 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; DIPEA; N,N-Diisopro

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Isoniazid induces apoptosis: Role of oxidative stress and inhibition of nuclear translocation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)

Keywords: Nrf2; nuclear factor erythoid 2-like 2; INH; isoniazid; DNA; deoxyribonucleic acid; Annexin V FITC; annexin V fluorescein isothiocyanate; DAPI; 4,6-diamino-2-phenylindole; FACS; fluorescence-activated cell sorting; PI; propidium iodide; Cyt C; cytochrome

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Bioconversion of alkaloids to high-value chemicals: Comparative analysis of newly isolated lupanine degrading strains

Keywords: Lupanine; Quinolizidine alkaloids; Biodegradation; Bioconversion; Toxicity assessment; M9; Minimal microbial growth medium; GC; Gas chromatography; EC50; Half maximal effective concentration; ITS; Internal transcribed spacer sequence; NCBI; National Cente

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Bisphenol A reduces testosterone production in TM3 Leydig cells independently of its effects on cell death and mitochondrial membrane potential

Keywords: AR; androgen receptor; BPA; bisphenol A; CI; cellular index; CYP11A1; cytochrome P450 family 11 subfamily a member 1; DMSO; dimethyl sulfoxide; ER; estrogen receptor; ERα; estrogen receptor alpha; ERβ; estrogen receptor beta; IC50; half-maximal inhibito

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

Keywords: Diabetes; α-Glucosidase; Inhibition; QSAR; Xanthone; Abs; absorbance; Ac; acetyl; Bn; benzyl; Bu; butyl; CoMFA; Comparative Molecular Field Analysis; CoMSIA; Comparative Molecular Similarity Indices Analysis; Et; ethyl; geranyl; -CH2CH=C(Me)-(CH2)2-CH=C(

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

3′-Hydroxy-3,4′-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK

Keywords: Apoptosis; Caspases; Cell cycle; Cytotoxicity; Flavonoids; ERKs; extracellular signal-regulated kinases; IC50; 50% inhibition of cell growth; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide; JNK; c-Jun N-terminal

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Androgen receptor (AR) degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth

Keywords: Androgen receptor; Prostate cancer; Prostate therapy; ASC-J9®; IC50; Epithelial cells; Stromal cells; Fibroblasts; Myofibroblasts; Apoptosis; FDA-approved formula; AR; androgen receptor; PCa; prostate cancer; RT-PCR; reverse transcription polymerase chai

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Novel approach to identify phenoloxidases inhibitors: Optimization of spectrophotometric MBTH assay for high throughput use enzymatic assays and analysis

Keywords: High throughput screening assay development; 3-Methyl-2-benzothiazolinone hydrazone hydrochloride; Spectrophotometric; Phenoloxidase inhibition; Post-mortem melanosis; Penaeus monodon.; POs; polyphenol oxidase type enzymes; MBTH; 3-methyl-2-benzothiazolin

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase inhibitors

Keywords: ABCG2; ATP-binding cassette sub-family G member 2; CI; combination index; D-VNR; deacetyl-vinorelbine; EGFR; epidermal growth factor receptor; FBS; fetal bovine serum; IC50; inhibitory concentration 50; mVNR; metronomic vinorelbine; NSCLC; Non Small Cell

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Manganese(II) complexes of tolfenamic acid or naproxen in polymeric structures or encapsulated in [15-MC-5] manganese(III) metallacrowns: Structure and biological activity

Keywords: 5FU; 5-fluorouracil; BSA; bovine serum albumin; CDDP; cisplatin; CI; Combination Index; CPT-11; irinotecan hydrochloride, trihydrate; CT; calf-thymus; CV; coefficient of variation; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; DRI; dose reduction i

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Specific enzyme functionalities of Fusarium oxysporum compared to host plants

Keywords: Ap4A; diadenosine tetraphosphate; CAT; carnitine acetyltransferase; CDP-choline; cytidine diphosphate choline; CWDEs; cell walls degrading enzymes; DcpS; decapping scavenger enzyme; EC; enzyme commission numbers; HCCS; holocytochrome-c synthase; HGT; hori

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

The S-layer biogenesis system of Synechocystis 6803: Role of Sll1180 and Sll1181 (E. coli HlyB and HlyD analogs) as type-I secretion components for Sll1951 export

Keywords: ABC; ATP-binding cassette; AF; Autofluorescence; AGE; Agarose gel electrophoresis; DAPI; 4′,6-diamidino-2-phenylindole; FE-SEM; Field emission scanning electron microscopy; FITC; Fluorescein isothiocyanate; GT; Glucose tolerant; Hly; hemolysin; IC50; In

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1-mediated metabolism to the product 4′ hydroxy tangeretin

Keywords: Flavonoids; Tangeretin; Cytochrome P450 CYP1 enzymes; Antiproliferation; Breast cancer; CYP1; cytochrome P450 CYP1B1 CYP1A1 and CYP1A2; HPLC; high pressure liquid chromatography; IC50; 50% inhibitory concentration; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-di

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Fermented non-digestible fraction from combined nixtamalized corn (Zea mays L.)/cooked common bean (Phaseolus vulgaris L.) chips modulate anti-inflammatory markers on RAW 264.7 macrophages

Keywords: AA; acetic acid; ATCC; American Type Cell Culture; BA; butyric acid; DCF; digested chip fraction; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified eagle medium; FNDCF; fermented non-digested chip fraction; GC-MS; gas chromatography-mass spectrometr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms

Keywords: AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphosulindac is efficacious in an improved concanavalin A-based rabbit model of chronic dry eye disease

Keywords: BSA; bovine serum albumin; Con A; concanavalin A; DED; dry eye disease; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; IC50; half-maximal inhibitory concentration; IL-1β;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions

Keywords: Uva-ursi extract; In vitro UGT1A1 inhibition; Gallotannin; 1,2,3,6-Tetragalloylglucose; In vivo herb‒drug interaction; UGT; UDP-glucuronosyltransferase; TeGG; 1,2,3,6-tetragalloylglucose; 4-MU; 4-methylumbelliferone; UDPGA; uridine 5′-diphosphoglucuro

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound

Keywords: Trypanosoma cruzi; Naphthoquinones; Trypanocidal activity; Chemotherapy; CD; Chagas disease; Bz; Benznidazole; Nif; Nifurtimox; ROS; Reactive oxygen species; CC50; Concentration of compound that reduces 50% of mammalian cell viability; IC50; Concentration

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy

Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

In silico and in vitro analysis of coumarin derivative induced anticancer effects by undergoing intrinsic pathway mediated apoptosis in human stomach cancer

Keywords: SBC; Apoptosis; Docking; ADME; Stomach cancer cell line (AGS); Anti-proliferative; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; ADME; absorption, distribution, metabolism and excretion; FBS; fetal bovine serum; RPMI; rosewell park m

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Vitis amurensis Rupr: A review of chemistry and pharmacology

Keywords: Vitis amurensis Rupr; Chemistry; Pharmacology; CYA; cyanidin; DEL; delphinidin; PET; petunidin; PEO; peonidin; MAL; malvidin; IC50; half maximal inhibitory concentration; LPS; lipopolysaccharide; MIC; Minimum Inhibitory Concentration; MBC; Minimum Bacteri

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract

Keywords: αA-WT; wild-type αA-crystallin; αA-R21Q; αA-crystallin mutant R21Q; sHSP; small heat shock protein; ACD; alpha crystallin domain; SEC; Size Exclusion Chromatography; Bis-ANS; 4,4′-Dianilino-1,1′-Binaphthyl-5,5′-Disulfonic Acid; ADH; alcohol

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease

Keywords: PK; pharmacokinetics; DMF; N,N,-dimethylfornamide; DCM; dichloromethane; CDI; carbonyl diimidazole; TLC; thin layer chromatography; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; N-hydroxybenzotriazole; DIEA; diisopropylethylamine; DTT; dithio

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites

Keywords: CYP4A11; Reaction phenotyping; HET0016; Plumbagin; Lauric acid metabolism; HLM; human liver microsomes; CYP; cytochrome P450; 20-HETE; 20-hydroxyeicosatetraenoic acids; LC-MS/MS; liquid chromatography-tandem mass spectrometry; IC50; the half maximal inh

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses

Keywords: Acylguanidine; Zanamivir; Oseltamivir; Neuraminidase inhibitor; Influenza; Arg; arginine; Boc; tert-butoxycarbonyl; (Boc)2O; di(tert-butyl) dicarbonate; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DIEA; diisopropyl ethylamine; D

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance

Keywords: ABS; Akaferd blood stopper; AN; Aspergillus niger; AO; Alpinia officinarum; BC; Bacillus cereus; B16-F10; Mouse melanoma cell line; CA; Candida albicans; CAR; Constitutive androstane receptor; CH2CL2; Dichloromethane; DPPH; Diphenylpicrylhydrazyl; EA; Eth

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Using bisphenol A and its analogs to address the feasibility and usefulness of the CALUX-PPARγ assay to identify chemicals with obesogenic potential

Keywords: Peroxisome proliferator-activated nuclear hormone receptor γ (PPARγ); CALUX; Obesogens; In vitro screening; Metabolism; Bisphenols; 15dPGJ2; 15-deoxy-Δ12,14-prostaglandin J2; 3OH BDE-47; 3-hydroxy BDE-47; 5OH BDE-47; 5-hydroxy BDE-47; BADGE; Bisphenol

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Phytochemical and pharmacological aspects of Cnidoscolus Pohl species: A systematic review

Keywords: Euphorbiaceae; Cnidoscolus; Secondary metabolites; Biological activities; NMR; nuclear magnetic resonance; HPLC; high-performance liquid chromatography; DPPH; 2,2-diphenyl-1-picrylhydrazyl; ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid); M

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative and systems pharmacology 2. In silico polypharmacology of G protein-coupled receptor ligands via network-based approaches

Keywords: GPCR; G protein-coupled receptor; EP4; prostaglandin E2 receptor EP4 subtype; LPAR; lysophosphatidic acid receptor; DTI; drug-target interaction; ADE; adverse drug event; MoA; mechanism of action; Ki; inhibition constant; Kd; dissociation constant; IC50;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii

Keywords: Toxoplasma gondii; ROP8; Bioinformatics analysis; Vaccine; 3D; three-dimensional; ACC; auto cross covariance; ANN; artificial neural network; CD; cluster of differentiation; CI; confidence interval; CTL; cytotoxic T lymphocyte; GOR; Garnier-Osguthorpe-Rob

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Cytotoxic effect of Kalanchoe flammea and induction of intrinsic mitochondrial apoptotic signaling in prostate cancer cells

Keywords: 2AA; 2-aminoanthracene; 4NQO; 4-nitroquinoline; BCA; bicinchoninic acid; Bcl-2; B-cell lymphoma 2; CA; coumaric acid; CAD; caspase-activated dnase; DAPI; 4',6-diamidino-2-phenylIndole; DCF; oxidize 2'-7'-dichlorodihydrofluorescein; DCFH; reduced 2â€

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Tricarbonylrhenium(I) complexes with the N-methylpyridine-2-carbothioamide ligand - Synthesis, characterization and cytotoxicity studies

Keywords: Tricarbonylrhenium(I) complexes; N-methylpyridine-2-carbothioamide; Crystal structure; DFT calculations; Cytotoxicity; IC50;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway

Keywords: Δψm; mitochondrial transmembrane potential; t-BHP; tert-butyl hydroperoxide; COX-2; cyclooxygenase-2; DCFDA; 2′,7′-dichlorofluorescein diacetate; DHE; dihydroethidium; GI50; dose of drug causing 50% inhibition of cell growth by MTT assay; G + M + S;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

β-Lapachone and its iodine derivatives cause cell cycle arrest at G2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells

Keywords: ctDNA; Calf thymus DNA; CTL; Negative control; DAF-FM diacetate; 4-amino-5-methylamino-2'-,7'-difluofluorescein diacetate; DCF-DA; 2',7'-dichlorodihydrofluorescein diacetate; DMSO; Dimethyl sulfoxide; DOX; Doxorubicin; FBS; Fetal bovine serum; FSC; Fo

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Optimized Camellia sinensis var. sinensis, Ilex paraguariensis, and Aspalathus linearis blend presents high antioxidant and antiproliferative activities in a beverage model

Keywords: Phenolic compounds; Antimicrobials; Response surface methodology; Cell viability; IC50; Reactive oxygen species; Desirability function;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils

Keywords: Eosinophil; Siglec-8; β2-integrin; apoptosis; phosphoproteomics; reduced nicotinamide adenine dinucleotide phosphate oxidase (NADPH); p38; c-Jun N-terminal kinase (JNK); Akt; DAPI; 4′-6-Diamidino-2-pheynlindole dihydrochloride; DAVID; Database for Anno

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway

Keywords: ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; LEG; lycopene-rich extract from red guava; ESI; electrospray ion; ATR-FTIR; Attenuated total reflectance-fourier transform infrared spectroscopy; DFT; density functional theory; PI; pro

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects

Keywords: B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Tithonia diversifolia (Hemsl.) A. Gray as a medicinal plant: A comprehensive review of its ethnopharmacology, phytochemistry, pharmacotoxicology and clinical relevance

Keywords: ABTS; 2,2′-Azinobis (3-ethylbenzothiazoline-6-sulphonate); Ach; acetyl choline; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; Aspartate transaminase; CAs; chlorogenic acids; CC5

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review

Keywords: AD; Alzheimer's disease; AcOEt; Ethyl acetate; AOE; Ethanolic extract of the fruit of A. oxyphylla; AOF; Alpinia oxyphylla fruit; BBB; Blood-brain barrier; CAT; Catalase; CCl4; Carbon tetrachloride; CKD; Chronic kidney disease; EA portion; Ethyl acetate-s

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review

Keywords: AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3′,4′-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation a

Keywords: ABAH; 4-aminobenzoic acid hydrazide; ANOVA; analysis of variance; CL-luc; lucigenin-enhanced chemiluminescence; CL-lum; luminol-enhanced chemiluminescence; CR; complement receptor; DAPI; 4',6-diamidino-2-phenylindole dihydrochloride; DMSO; dimethyl sulfox

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer

Keywords: CIL-102 derivatives; CR PCa; Docetaxel-resistant cancer; Anti-microtubule agents; Selectivity; Androgen deprivation therapy; ADT; Androgen-independent; AI; Androgen receptor; AR; Androgen-sensitive; AS; Castration-Resistant Prostate Cancer; CRPC; dichloro

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه