Keywords: انسولین گیرنده زیربخش 1; CREB; cAMP response element binding protein; AMPK; adenosine monophosphate-activated protein kinase; SCN; suprachiasmatic nucleus; TTFL; transcriptional-translational feedback loop; CR; constant routine; FD; forced desynchrony; CA/M; circadian alignment/m
مقالات ISI انسولین گیرنده زیربخش 1 (ترجمه نشده)
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Keywords: انسولین گیرنده زیربخش 1; AC; anthocyanidins; GIP; gastric inhibitory polypeptide; GLP-1; glucagon-like peptide-1; GTT; glucose tolerance test; HFD; high fat diet; 4-HNE; 4-hydroxynonenal; IKK; IκB kinase; IRS1; insulin receptor substrate-1; ITT; insulin tolerance test; JNK; c-ju
Keywords: انسولین گیرنده زیربخش 1; Cardiomyocytes swelling; Glucose uptake; Insulin receptor substrate-1; Losartan; Secreted Angiotensin II;
Keywords: انسولین گیرنده زیربخش 1; Chromium toxicity; Glucose homeostasis; Insulin receptor; Glucose transporters; CrVI; Hexavalent chromium; CrIII; Trivalent chromium; IR; Insulin receptor; IRS-1; Insulin receptor substrate-1; GLUT 2/4; Glucose transporters 2/4; ppm; parts per million; GT
Keywords: انسولین گیرنده زیربخش 1; β-AR; β-adrenergic receptor; 4-HNE; 4-hydroxynonenal; ACC; acetyl-coA carboxylase; ALT; alanine aminotransferase; AMPK; adenosine monophosphate-activated protein kinase; ANOVA; analysis of variance; AST; aspartate transaminase; ATGL; adipose triglycerid
Keywords: انسولین گیرنده زیربخش 1; Aβ; amyloid-β; AβO; Aβ oligomers; βAPP; β-amyloid precursor protein; BDNF; brain-derived neurotrophic factor; CaMKII; calcium/calmodulin-dependent protein kinase II; Cer; cerebellum; ChAT; choline acetyltransferase; Cx; cortex; CxFr; cortex frontal;
Keywords: انسولین گیرنده زیربخش 1; GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: انسولین گیرنده زیربخش 1; CAT; catalase; C; control; CYP 2A6; cytochrome P450 2A6; FAS; fatty acid synthase; GPx; glutathione peroxidase; 4HNE; 4-hydroxy-2-nonenal; IRS1; insulin receptor substrate-1; MDA; malondialdehyde; NADPH; nicotinamide adenine dinucleotide phosphate-oxidase
Keywords: انسولین گیرنده زیربخش 1; α-TOS; α-tocopheryl succinate; BAP1; BRCA1 associated protein-1; BRCA1; breast cancer susceptibility gene 1; CDK4; cyclin-dependent kinase 4; CEA; carcinoembryonic antigen; CSC(s); cancer stem(-like) cell(s); CTGF; connective tissue growth factor (CCN2)
Keywords: انسولین گیرنده زیربخش 1; 5-aza-CdR; 5-aza-2â²-deoxycytidine; AML; acute myeloid leukemia; ANRIL; antisense non-coding RNA in the INK4 locus; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A; CoREST; co-repressor for element-1-silencing transcription factor
Keywords: انسولین گیرنده زیربخش 1; IL-6; Interleukin-6; DXA; dual energy x-ray absorptiometry; BMI; body mass index; HDL; high-density lipoprotein; PPARγ; the nuclear hormone receptor peroxisome proliferator-activated receptor γ; CEBP; CCAAT/enhancer binding protein; PLIN; perilipin; GLU
Keywords: انسولین گیرنده زیربخش 1; ADAM; (a disintegrin and metalloprotease) metallopeptidase; ALPs; alkyl-lysophospholipids; CD24; signal transducer CD24 (glycosylphosphatidylinositol-anchored receptor); CD44; CD44 antigen (receptor for hyaluronic acid); CXCR4; chemokine receptor type 4;
Keywords: انسولین گیرنده زیربخش 1; Alzheimer's disease; Glucagon-like peptide-1; Inflammation; Insulin receptor; Insulin receptor substrate-1; Insulin signaling; Hippocampus; Liraglutide; Streptozotocin; Type 3 diabetes;
Keywords: انسولین گیرنده زیربخش 1; IR; insulin receptor; IRS1; insulin receptor substrate-1; IGF-R; insulin growth factor receptor; EGF; epidermal growth factor; MMP; matrix metalloproteinase; RTK; receptor tyrosine kinase; NGF; nerve growth factor; Neu1; mammalian neuraminidase-1; 4-MUNAN
Keywords: انسولین گیرنده زیربخش 1; 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f
Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance
Keywords: انسولین گیرنده زیربخش 1; aPKC; atypical protein kinase C; ACC; acetyl-CoA carboxylase; ACPD; 2-acetyl-cyclopentane-1,3-dione; AMPK; AMP-activated protein kinase; Akt; protein kinase B; FAS; fatty acid synthase; FoxO1; forkhead homeobox class O1 protein; G6Pase; glucose-6-phosphat
Pharmacological effects and potential therapeutic targets of DT-13
Keywords: انسولین گیرنده زیربخش 1; ADP; adenosine diphosphate; Akt; protein kinsase B; ALT; alanine transaminase; APD; action potential duration; AST; aspartate transaminase; Atg; autophagocytosis associated protein; CCR5; C, C chemokine receptor type 5; CXCR4; C-X-C chemokine receptor typ
Biased G protein-coupled receptor agonism mediates Neu1 sialidase and matrix metalloproteinase-9 crosstalk to induce transactivation of insulin receptor signaling
Keywords: انسولین گیرنده زیربخش 1; GPCR; G-protein coupled receptor; 4MUNANA or 4-MU; 2â²-(4-methylumbelliferyl)-α-D-N-acetylneuraminic acid; OP; oseltamivir phosphate; MMP; matrix metalloproteinase; NMBR; neuromedin B receptor; BR2; bradykinin receptor; AT2R or AngIIR1; angiotensin II r
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Keywords: انسولین گیرنده زیربخش 1; 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell
Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3,4,5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Keywords: انسولین گیرنده زیربخش 1; C1-Ten/Tensin2; Src-homology 2 domain; Insulin receptor substrate-1; Phosphatidylinositol-3,4,5-triphosphate binding; Protein tyrosine phosphatase; PTP; protein tyrosine phosphatase; IRS-1; insulin receptor substrate-1; PI3K; phosphoinositide 3-kinase; C1
A new hypoglycemic mechanism of catalpol revealed by enhancing MyoD/MyoG-mediated myogenesis
Keywords: انسولین گیرنده زیربخش 1; CON; control non-treated mice; STZ; streptozotocin; PI3K; phosphatidylinositolâ3âKinase; AKT; protein kinase B; GLUT4; glucose transporter protein 4; IRS-1; insulin receptor substrate-1; HG; high glucose; GAPDH; glyceraldehyde 3âphosphate dehydrogen
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway
Keywords: انسولین گیرنده زیربخش 1; HFD; high fat-diet; STZ; streptozotocin; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; PEPCK; phosphoenolpyruvate carboxykinase; G6pase; glucose 6-phosphatase; FOXO1; forkhead box O1; GSK3β; glycogen synthase kinase-3β; GS; g
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
Keywords: انسولین گیرنده زیربخش 1; Vascular smooth muscle; Vasoproliferative disease; Vascular smooth muscle cell; Phenotype switching; Signalling pathways; AJ; adherens junction; ApoE; apolipoprotein E; BMP; bone morphogenetic protein; CAD; coronary artery diseases; CADASIL; cerebral auto
Oncogenic mutations of PIK3CA and HRAS in carcinoma of cervix in South Indian women
Keywords: انسولین گیرنده زیربخش 1; Oncogenic mutations; Cervical cancer; Peripheral blood; PCR-CTPP method; PIK3CA; Phosphatidylinositol-4,5-Bisphosphate; 3-Kinase Catalytic Subunit Alpha; HRAS; Harvey rat sarcoma viral oncogene homolog; EGF; Epidermal Growth Factor; PDGF; Platelet Derived
Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways
Keywords: انسولین گیرنده زیربخش 1; Icariin; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Phosphatidylinositol 3-kinase; Mitogen-activated protein kinase kinase; Dopamine; Parkinson's disease; DA; dopamine; IGF-1R; insulin-like growth factor-1 receptor; IRS-1; insulin receptor substrate-1;
Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats
Keywords: انسولین گیرنده زیربخش 1; Paeoniflorin; Diabetes; Cognitive dysfunction; SOCS2/IRS-1; Tau phosphorylation; Akt; protein kinase B; DE; diabetic encephalopathy; DM; diabetes mellitus; GSK-3β; glycogen synthase kinase-3β; IL-1β; interleukin-1β; IRS-1; insulin receptor substrate-1
The roles of extracellular related-kinases 1 and 2 signaling in CNS myelination
Keywords: انسولین گیرنده زیربخش 1; Erk; Akt; Fyn; BDNF; Oligodendrocyte; Myelin; Erk1/2; extracellular related-kinase 1 and 2; BDNF; brain-derived neurotrophic factor; NGF; nerve growth factor; NT-3; neurotrophin 3; CNS; central nervous system; PNS; peripheral nervous system; p75NTR; p75 n
Thyroid-stimulating hormone improves insulin sensitivity in skeletal muscle cells via cAMP/PKA/CREB pathway-dependent upregulation of insulin receptor substrate-1 expression
Keywords: انسولین گیرنده زیربخش 1; Thyroid-stimulating hormone; Insulin sensitivity; Skeletal muscle; Insulin receptor substrate-1;
Elucidation of hypoglycemic action and toxicity studies of insulin-like protein from Costus igneus
Keywords: انسولین گیرنده زیربخش 1; BCA; bicinchoninic acid; ILP; insulin-like protein from Costus igneus; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; GLUT-4; glucose transporter-4; IR; insulin receptor; IRS-1; insulin receptor substrate-1; 2-NBDG; [2-{N-(7-nitrob
N â 3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells
Keywords: انسولین گیرنده زیربخش 1; 2-NBDG; fluorescent glucose analog; ALA; alpha-linolenic acid; AMPK; AMP-activated protein kinase; AS160; AKT substrate of 160Â kDa; cpt1; carnitine palmitoyltransferase 1; DMEM; Dulbecco's modified eagle medium; DHA; docosahexaenoic acid; DPH; diphenyl-h
Oral administration of SR-110, a peroxynitrite decomposing catalyst, enhances glucose homeostasis, insulin signaling, and islet architecture in B6D2F1 mice fed a high fat diet
Keywords: انسولین گیرنده زیربخش 1; Diabetes; Peroxynitrite; Glucose homeostasis; Islet architecture; Insulin content; Nitrotyrosine; Insulin signaling; HFD; high fat diet; IPGTT; intra-peritoneal glucose tolerance test; mAB; monoclonal antibody; SR-135; Mn(III) complex of 3,5-bis(hydroxyph
Intrathecal administration of rapamycin inhibits the phosphorylation of DRG Nav1.8 and attenuates STZ-induced painful diabetic neuropathy in rats
Keywords: انسولین گیرنده زیربخش 1; STZ; streptozotocin; PDN; painful diabetic neuropathy; DRG; dorsal root ganglion; mTOR; mammalian target of rapamycin; S6K; ribosomal protein S6 kinase; 4E-BP; eukaryotic initiation factor 4E (eIF4E) binding protein; IR; insulin receptor; IRS-1; insulin r
Entada phaseoloides extract suppresses hepatic gluconeogenesis via activation of the AMPK signaling pathway
Keywords: انسولین گیرنده زیربخش 1; ACC; acetyl coenzyme A carboxylase; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; CCK-8; cell counting kit-8; Dex/cAMP; dexamethasone/cAMP; Entada phaseoloides; Entada phaseoloides (L.) Merr.; G6pase; glu
Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors
Keywords: انسولین گیرنده زیربخش 1; Lipolysis; Type 2 diabetes; Adipose tissue; Metabolism; Lipid storage; ADRA2A; adrenoreceptor alpha 2 A; AT; Adipose tissue; FABP4; Fatty acid binding protein 4; FASN; Fatty acid synthase; IRS1; Insulin receptor substrate-1; GLUT4 and SLC2A4; Glucose tran
Synergistic induction of insulin resistance by endothelin-1 and cAMP in 3T3-L1 adipocytes
Keywords: انسولین گیرنده زیربخش 1; Endothelin-1; cAMP; Insulin resistance; Insulin receptor substrate-1; Insulin receptor substrate-2; Adipocytes; β-Adrenergic agonists
A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development
Keywords: انسولین گیرنده زیربخش 1; N-acetyl-l-cysteine (NAC) (PubChem CID: 12035); AKT; protein kinase B; AP-1; activator protein 1; CCL2; chemokine (C-C motif) ligand 2; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; FFA; free fatty acid; GLUT; gluc
Nymphayol increases glucose-stimulated insulin secretion by RIN-5F cells and GLUT4-mediated insulin sensitization in type 2 diabetic rat liver
Keywords: انسولین گیرنده زیربخش 1; DM; diabetes mellitus; STZ; streptozotocin; NA; nicotinamide; NSFCExt; Nymphaea stellata flower chloroform extract; XRD; X-ray crystallography; IRS1; insulin receptor substrate-1; GLUT4; glucose transporter-4; G6PDH; glucose-6-phosphate dehydrogenase; G6P
Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade
Keywords: انسولین گیرنده زیربخش 1; IR; insulin receptor; IGFR; insulin-like growth factor receptor; IRS-1; insulin receptor substrate-1; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of rapamycin; Grb2; growth factor receptor-bound protein 2; FGF2; fibroblast growth factor 2; DTP
Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: The relationship to AMPK activation
Keywords: انسولین گیرنده زیربخش 1; Triterpenoids; Cyclocarya paliurus; Inflammation; Insulin resistance; Glucose uptake; AMPK; Cyclocaric acid B (CAS No. 182315-46-4); Cyclocarioside H (CAS No. 1403937-87-0); Akt; Protein kinase B; AMPK; AMP-activated protein kinase; AUC; Area under the cu
Molecular and cellular pharmacologyAegeline from Aegle marmelos stimulates glucose transport via Akt and Rac1 signaling, and contributes to a cytoskeletal rearrangement through PI3K/Rac1
Keywords: انسولین گیرنده زیربخش 1; IRS-1; Insulin receptor substrate-1; PI-3-K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; AS160; Akt substrate of 160Â kDa; SE; Standard error; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HG-DMEM; High glucose-Dulbecco's Modifi
NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells
Keywords: انسولین گیرنده زیربخش 1; DCF-DA; 2â²,7â²-dichlorofluorescin diacetate; DPI; diphenyliodonium; IRS-1; insulin receptor substrate-1; MDP; muramyl dipeptide; NAC; N-acetylcysteine; NOD; nucleotide binding oligomerization domain protein; OCR; oxygen consumption rates; PRR; pattern
Laboratory StudiesArg972 insulin receptor substrate-1 polymorphism and risk and severity of Alzheimer's disease
Keywords: انسولین گیرنده زیربخش 1; Alzheimer's disease; Case-control study; Cognitive impairment; Gene polymorphism; Insulin receptor substrate-1; Mini-Mental State Examination;
The glucagon-like peptide 1 receptor agonist enhances intrinsic peroxisome proliferator-activated receptor γ activity in endothelial cells
Keywords: انسولین گیرنده زیربخش 1; GLP-1; glucagon-like peptide-1; HUVECs; human umbilical vein endothelial cells; PKA; protein kinase A; IRS-1; insulin receptor substrate-1; JNK; c-Jun N-terminal kinase; NF-κB; nuclear factor-kappa B; TNFα; tumor necrosis factor α; ICAM-1; intercellula
Saturated fatty acid-induced miR-195 impairs insulin signaling and glycogen metabolism in HepG2 cells
Keywords: انسولین گیرنده زیربخش 1; MicroRNA; MiR-195; Saturated fatty acid; Palmitate; Insulin resistance; Insulin receptor; Insulin receptor substrate-1;
Aganirsen Antisense Oligonucleotide Eye Drops Inhibit Keratitis-Induced Corneal Neovascularization and Reduce Need for Transplantation: The I-CAN Study
Keywords: انسولین گیرنده زیربخش 1; ANCOVA; analysis of covariance; CI; confidence interval; IRS-1; insulin receptor substrate-1; ITT; intention-to-treat; I-CAN; Inhibition of CorneAl Neovascularization; PP; per protocol; QoL; quality of life; SAE; serious adverse event; TEAE; treatment-eme
Regulation of contractile signaling and matrix remodeling by T-cadherin in vascular smooth muscle cells: Constitutive and insulin-dependent effects
Keywords: انسولین گیرنده زیربخش 1; E; empty vector control transductant; EC; endothelial cell; ECM; extracellular matrix; ED; endothelial dysfunction; Ins; insulin; IRS-1; insulin receptor substrate-1; MLC20; myosin light chain 20; MLCK; myosin light chain kinase; MLCP; myosin light chain
Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: Focus on the role and impact of proteoglycans
Keywords: انسولین گیرنده زیربخش 1; ER; estrogen receptor; PgR; progesterone receptor; HER2/erbB2; human epidermal growth factor receptor-2; E2; estradiol; RTK; receptor tyrosine kinase; IGF-IR; insulin-like growth factor I receptor; EGFR; epidermal growth factor receptor; MAPK; mitogen act
MicroRNAs as regulators of mitochondrial function: Role in cancer suppression
Keywords: انسولین گیرنده زیربخش 1; ACL; ATP citrate lyase; AGO; Argonaut; ARL2; ADP-ribosylation factor-like 2; BH3; Bcl-2 homology-3; CAT; catalase; COX IV; cytochrome c oxidase IV; CI; complex I; CII; complex II; CIV; complex IV; CPT; camptothecin; DGCR8; DiGeorge syndrome critical regio
Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance
Keywords: انسولین گیرنده زیربخش 1; ABAF; anti-bacterial, anti-fungal; ANOVA; analysis of variance; AS160; Akt substrate of 160Â kDa; BSA; bovine serum albumin; CM; conditioned medium; CXCL2; Chemokine (C-X-C motif) ligand 2; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulphox
Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum
Keywords: انسولین گیرنده زیربخش 1; AMPK; AMP-activated protein kinase; STAT; activator of transcription; AGE; advanced glycation end products; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β peptide; ACE; angiotensin converting enzyme; Ang I; angiotensin I; AR-II;