Keywords: چگونه; ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph
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Keywords: چگونه; Mammary gland; Embryogenesis; Development; Endocrine signals; AR; androgen receptor; AP1; APETALA1; BMP4; bone morphogenetic protein 4; CEBPB; CCAAT/enhancer binding protein (C/EBP), beta; Dvl1; disheveled segment polarity protein 1; EDA-R; death receptor
Keywords: چگونه; AGRP; Agouti-related peptide; BBB; Blood-brain barrier; CART; Cocaine- and amphetamine-regulated transcript; CAD; Cardiovascular disease; FNDC; Fibronectin type III domain-containing protein; HAART; Highly active antiretroviral therapy; HIV; Human immun
Keywords: چگونه; leptin receptor; leptin resistance; obesity; diabetes; shedding; ADAM proteaseOB-R, leptin receptor; sOB-R, soluble leptin receptor; ADAM, a disintegrin and metalloprotease; GCSF, granulocyte-colony stimulating factor; LIF, leukemia inhibitory factor; JAK
Keywords: چگونه; EPOR; erythropoietin receptor; HIF; hypoxia-inducible factors; IGF-1; insulin growth factor-1; IGFBP3; insulin-like growth factor binding protein 3; IVNV; intravitreal neovascularization; JAK; Janus-activated kinase; OIR; oxygen-induced retinopathy; PRVD;
Keywords: چگونه; AKT; protein kinase B; ATM; ataxia-telangiectasia mutated; ELISA; enzyme-linked immunosorbent assay; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; GSK; glycogen synthase kinase; hSAEC; human small airway epithelial
Keywords: چگونه; ABCA1; ATP-binding cassette, subfamily A, member 1; ABCG5; ATP-binding cassette, subfamily G, member 5; ACD; anemia of chronic disease; AI; anemia of inflammation; Apo; apolipoprotein; Arg1; arginase-1; Bach1; Btb and Cnc Homology, basic leucine zipper tr
Keywords: چگونه; Corticosteroids; bronchodilator; cytokine; chemokine; IgE; kinase; p38 mitogen-activated protein kinase; bronchial thermoplasty; corticosteroid resistance; macrolide; ACOS; Asthma-chronic obstructive pulmonary disease overlap syndrome; COPD; Chronic obs
Keywords: چگونه; ABL; Abelson; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; BC; blast crisis; BCR; breakpoint cluster region; BMP; bone morphogenetic protein; CBP; CREB-binding protein; CDK; cyclin dependent kinase; CEBP
Keywords: چگونه; 4-AP; 4-aminopyridine; APC; antigen presenting cell; ApoE; apolipoprotein E; ATRA; all-trans-retinoic acid; BBB; blood brain barrier; BBI; Bowman-Birk inhibitor; CB1/2; cannabinoid receptor; CBD; cannabidiol; CNS; central nervous system; DC; dendritic c
Keywords: چگونه; BDNF; brain-derived neurotrophic factor; BNB; blood-nerve barrier; CCL2; chemokine C-C motif ligand 2; CCR2; chemokine C-C motif receptor 2; CGRP; calcitonin gene-related peptide; CL; conditioning lesion; CNS; central nervous system; CNTF; ciliary n
Keywords: چگونه; cIFN; consensus interferon; EDHS; Egyptian Demographic Health Survey; FDA; Food and Drug Administration; HBV; hepatitis B virus; HCV; hepatitis C virus; IFN; interferon; IFNAR; IFN-α/β receptor; IFNGR; IFN-γ receptor; IRF9; IFN-regulatory factor 9; ISG
Keywords: چگونه; AMPK; 5â²-adenosine monophosphate-activated protein kinase; BMI; body mass index; CHB; chronic hepatitis B; CHC; chronic hepatitis C; ChREBP; carbohydrate response element binding protein; Fox; forkhead box protein; HCC; hepatocellular carcinoma; HSCs;
Keywords: چگونه; PDGF-A; platelet-derived growth factor-A; CK2; casein kinase 2; Bcl-2; B-cell lymphoma-2; PARP; poly-(ADP-ribose) polymerase; IAP; inhibitor of apoptosis protein; XIAP; X-linked inhibitor of apoptosis protein; 8-tBid; caspase-8-cleaved Bid; CBF1; C-repeat
Keywords: چگونه; 2 DE; 2-dimensional electrophoresis; ABPP; activity-based protein profiling; BFGF; basic fibroblast growth factor; CML; chronic myeloid leukemia; CRC; colorectal cancer; DIGE; differential in gel electrophoresis; EGF(R); epidermal growth factor (receptor)
Keywords: چگونه; Astrocytes; Glial scar; Transcription factors; Brain pathology; IF; intermediate filament; GFAP; glial fibrillary acidic protein; AxD; Alexander disease; AD; Alzheimer disease; ECM; extracellular matrix; FAK; focal adhesion kinase; FA; focal adhesion; MMP
Keywords: چگونه; BMMCs; bone marrow-derived mast cells; FA; food allergy; JAK; Janus kinase; MCs; mast cells; MMCP; mouse mast cell protease; OVA; ovalbumin; PSA; passive systemic anaphylaxis; STAT; signal transducer and activator of transcription; Tr; regulatory T cell t
Keywords: چگونه; ECM; extracellular matrix; EGF; epidermal growth factor; EOC; epithelial ovarian cancer; G-CSF; granulocyte colony-stimulating factor; GP130; glycoprotein 130; IL; interleukin; JAK; Janus kinase; LIF; leukemia inhibitory factor; MAPK; mitogen-activated pr
Keywords: چگونه; Interleukin-6 (IL-6); Metabolic disease; IL-6; interleukin-6; MS; metabolic syndrome; ROS; reactive oxygen species; IFN; interferon; hIL-6; human interleukin-6; SHP-2; Src homology domain-containing protein tyrosine phosphatase-2; IR; insulin resistance;
Keywords: چگونه; 5-FU; 5-fluorouracil; AR; apoptotic resistance; ASK1; apoptosis signal-regulating kinase 1; BD,; bruceine D; COX-2; cyclooxygenase-2; EGCG,; epigallocatechin-3-gallate; EGFR,; epidermal growth factor receptor; EriB; eriocalyxin B; ERK,; extracellular sign
Keywords: چگونه; Aβ; β-amyloid; AGE; advanced glycation end product (here: proteins modified by AGEs); Atg; autophagy-related gene; CMA; chaperone-mediated-autophagy; 3-DG; 3-deoxyglucosone; FIP200; focal adhesion kinase family-interacting protein of 200 kDa; IP3; inos
Keywords: چگونه; Senolytic; an agent that targets senescent cells; ADME; absorption, distribution, metabolism, and excretion of a drug; SASP; senescence-associated secretory phenotype; mTOR; mammalian target of rapamycin; JAK; Janus-activated kinase; GLP; good laboratory
Keywords: چگونه; BMI; body mass index; CRP; C-reactive protein; db/db; diabetic; ER; endoplasmic reticulum; HSP; heat shock proteins; JAK; janus kinase; ob/ob; obese; LEPR; leptin receptor; MAPK; mitogen-activated protein kinase; mTOR; mammalian target of rapamycin; NK; n
Keywords: چگونه; IL; interleukin; IL-R; IL-receptor; IFN-γ; interferon-γ; TNF-α; tumor necrosis factor α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; JAK; Janus kinase; HEK; human embryonic kidney; MOG35-55; myelin oligodendro
Keywords: چگونه; ALS; amyotrophic lateral sclerosis; ASO; antisense oligonucleotide; BBB; blood brain barrier; CREB; cyclic AMP response element binding protein; FDA; Food and Drug Administration; GSK-3; glycogen synthase kinase 3; HDAC; histone deacetylase; hnRNP A1; het
Keywords: چگونه; Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
Keywords: چگونه; ACTRIIB; activin receptor type-2B; APC; adenomatosis polyposis coli; APPR; acute phase protein response; ARC; arcuate nucleus; ATP; adenosine-5â²-triphosphate; C-26; colon-26 adenocarcinoma mouse model; CHO; Chinese hamster ovary; COPD; chronic obstructi
Keywords: چگونه; AAV; adeno-associated viruses; Ad6; adenovirus serotype 6; ABCB5Â +; ATP-binding cassette sub-family B member 5; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; APCs; antigen presenting cells; B7.1; (CD80) cluster of differentiation 80; BCG; Ba
Rosmarinus officinalis essential oil: A review of its phytochemistry, anti-inflammatory activity, and mechanisms of action involved
Keywords: چگونه; AA; Arachidonic Acid; ABST; 2,2â²-Azino-Bis(3-ethylbenzothiazoline-6-Sulfonic Acid); COX; Cyclooxygenase; DAMP; Damage-Associated Molecular Pattern; DMSO; Dimethyl Sulfoxide; DPPH; 2,2-Diphenyl-1-Picryl-Hydrazyl-Hydrate; EORO; Essential oil of Rosmarinus
Balance of tofacitinib efficacy and disease flare in the treatment of alopecia universalis: A case report and review of the literature
Keywords: چگونه; alopecia universalis; Janus kinase inhibition; tofacitinib; AA; alopecia areata; AT; alopecia totalis; AU; alopecia universalis; JAK; Janus kinase; IFN; interferon;
GT-repeat extension in the IL11 promoter is associated with Hirschsprung's disease (HSCR)
Keywords: چگونه; AGT; angiotensinogen; ALDH2; dehydrogenase 2; APC; antigen-presenting cell; CD11c; cluster of differentiation 11c; CI; confidence interval; COPD; chronic obstructive pulmonary disease; CLL; chronic lymphocytic leukemia; DENND3; DENN domain containing prot
Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice
Keywords: چگونه; Interleukin 11; Proliferation; STAT3; CRISPR-Cas9; Knockout mice; CRISPR; Clustered regularly interspaced short palindromic repeats; STAT; Signal transducer and activator of transcription; AOM; Azoxymethane; DSS; dextran sulfate sodium; IL; Interleukin; J
PMA treated THP-1-derived-IL-6 promotes EMT of SW48 through STAT3/ERK-dependent activation of Wnt/β-catenin signaling pathway
Keywords: چگونه; Colon cancer; β-Catenin; IL-6; EMT; JAK; STAT3; ERK;
Deciphering the pathways that protect from IL-13-mediated potentiation of oxidative stress-induced dopaminergic nerve cell death
Keywords: چگونه; Parkinson's disease; mTOR; Jak; Akt; 4E-BP1; Oxidative stress; BSA; bovine serum albumin; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dichlorofluorescein diacetate; mTOR; mammalian target of rapamycin; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetr
Analysis of miRNA expression in patients with rheumatoid arthritis during remission and relapse after a 5-year trial of tofacitinib treatment
Keywords: چگونه; miRNA; Tofacitinib; JAK; STAT; Firefly Bioworks;
Leptin in autoimmune mechanisms of systemic rheumatic diseases
Keywords: چگونه; Leptin; Connective tissue diseases; Adipokines; Inflammatory arthritis; Vasculitis; WAT; white adipose tissue; IL; interleukin; BMI; body mass index; PPAR; peroxisome proliferator-activated receptor; JAK; janus kinases; STAT; signal transducers and activa
Enhanced perforin expression associated with dasatinib therapy in natural killer cells
Keywords: چگونه; Dasatinib; JAK; STAT; Perforin; Interferon-γ; IL-2;
Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases
Keywords: چگونه; aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd
T-cell-mediated immune response to pneumococcal conjugate vaccine (PCV-13) and tetanus toxoid vaccine in patients with moderate-to-severe psoriasis during tofacitinib treatment
Keywords: چگونه; immune response; Janus kinase inhibitor; pneumococcal vaccine; T cell; tetanus toxoid; tofacitinib; CI; confidence interval; ELISA; enzyme-linked immunosorbant assay; GMFR; geometric mean fold rise; JAK; Janus kinase; LTE; long-term extension; OPA; opsono
Hypoxia enhances H2O2-mediated upregulation of hepcidin: Evidence for NOX4-mediated iron regulation
Keywords: چگونه; β2mg; β2-microglobulin; BMP; Bone morphogenetic protein; CAT; Catalase; FPN1; ferroportin 1; GOX; Glucose Oxidase; HIF; Hypoxia inducible factor; IL-6; Interleukin 6; JAK; Janus kinase; NOX; NADPH oxidase; ODD; Oxygen-dependent degradation domain; PHD2;
GH directly stimulates UCP3 expression
Keywords: چگونه; aSTAT5B; constitutively active STAT5B; ANOVA; analysis of variance; BLAST; Basic Local Alignment Search Tool; DMEM; Dulbecco's Modified Eagle's Medium; GAS; interferon-gamma activated sequence; GH; growth hormone; GHR; growth hormone receptor; IGF-1; insu
Repression of interferon β-regulated cytokines by the JAK1/2 inhibitor ruxolitinib in inflammatory human macrophages
Keywords: چگونه; Ruxolitinib; JAK; Macrophage; Inflammation; Cytokine;
Monoclonal antibodies against interleukin 13 and interleukin 31RA in development for atopic dermatitis
Keywords: چگونه; atopic dermatitis; dipeptidyl peptidase-4; Eczema Area and Severity Index; interleukin; IL-31RA; Investigator's Global Assessment; Janus kinase; c-Jun N-terminal kinase; mitogen-activated protein kinase; oncostatin M receptor β; STAT signal transducer a
Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review
Keywords: چگونه; ERK; extracellular signal-regulated kinase; EtOAc; ethyl acetate; EtOH; ethyl alcohol; COX-2; cyclooxygenase-2; IL; interleukin; INF-γ; interferon γ; JAK; Janus kinases; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MIC; minimum inhib
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: چگونه; NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance
Keywords: چگونه; ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt
Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations
Keywords: چگونه; Signal transducer and activator of transcription 1, gain of function; natural killer cell deficiency; perforin; Janus kinase inhibition; ruxolitinib; natural killer cell maturation; ADCC; Antibody-dependent cellular cytotoxicity; CCD; Coiled-coil domain;
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: چگونه; Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
Regulation of granulocyte colony-stimulating factor receptor-mediated granulocytic differentiation by C-mannosylation
Keywords: چگونه; C-mannosylation; Glycosylation; Granulocyte colony-stimulating factor receptor (G-CSFR); Mass spectrometry; Myeloid differentiation; TSR; thrombospondin type 1 repeat; G-CSF; granulocyte colony-stimulating factor; G-CSFR; granulocyte colony-stimulating fa
Computational design and experimental characterization of a novel β-common receptor inhibitory peptide
Keywords: چگونه; EPO; erythropoietin; βCR; beta common receptor; IL; interleukin; GM-CSF; graulocyte macrophage colony stimulating factor; JAK; janus kinase; STAT; signal transducer and activator of transcription; MAPK; mitogen-activated protein kinase; PI3K; phosphatidy