Keywords: MAP1LC3; microtubule-associated protein 1 light chain 3; LAMP1; lysosomes associated membrane protein 1; ROS; reactive oxygen species; EGCG; epigallocatechin gallate; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; VDAC1; voltage-dependent anion-selective
مقالات ISI (ترجمه نشده)
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Keywords: SCA21; spinocerebellar ataxia type 21; TMEM240; transmembrane protein 240; LAMP2A; lysosome-associated membrane protein 2a; TSG101; tumor susceptibility gene 101; Iba1; ionized calcium-binding adapter molecule 1; GFAP; glial fibrillary acidic protein; LC3
Keywords: APC; antigen-presenting cell; ATG; autophagy-related gene; ATP; adenosine triphosphate; ANXA1; annexin A1; BECN1; beclin-1; CD; cluster of differentiation; CRT; calreticulin; CTL; cytotoxic T lymphocyte; (CTLA)-4; CTL associated protein-4; DAMP; danger-as
Keywords: LAMP1; lysosomal associated membrane protein 1; ESCC; esophageal squamous cell carcinoma; IHC; immunohistochemistry; TMAs; tissue microarrays; Lysosomal associated membrane protein 1; Histological differentiation; Immunohistochemistry; Esophageal tumor;
Keywords: AraC; cytosine arabinoside; αSyn; α-synuclein; BSA; bovine serum albumin; Con; control; CQ; chloroquine; DIV; days in vitro; DMSO; dimethyl sulfoxide; E. coli; Escherichia coli; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; G
Keywords: ACP2; lysosomal acid phosphatase; ACP5; tartrate-resistant lysosomal acid phosphatase; ATF6; activating transcription factor 6; Canx; calnexin; CHO-7; Chinese hamster ovary cells; DAPI; 4â²,6â²-diamidino-2-phenylindol; DMAP; DNA methyltransferase-associ
Keywords: Mitophagy; Keima; Lamp1;
Keywords: Lamp1; Lysosomal-associated membrane protein 1; ConA; Concanamycin A; LC; Lactacystin. DTT, Dithiothreitol; LC3; Microtubule-associated protein 1A/1B-light chain 3; mTOR; mammalian target of rapamycin; ATGs; Autophagy-related proteins; ALP; Autophagy-Lyso
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ANOVA; Analysis of variance; Aβ; amyloid β; bHLH; basic Helix-Loop-Helix; C4; complement C4; CLEAR; coordinated lysosomal expression and regulation; Cyba; cytochrome b-245 light chain; DW; d
A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome
Keywords: AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Arf6; ADP-ribosylation factor 6; ARNO; ADP-ribosylation factor nucleotide site opener; AP-1; Chinese hamster ovary (CHO) cells deficient in the Na+/H+ exchanger 1 isoform; CANX; calnex
6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells
Keywords: PD; Parkinson's disease; iPSC; induced pluripotent stem cells; 6-OHDA; 6-hydroxydopamine; DAT; dopamine transporter; ROS; reactive oxygen species; TUNEL; terminal deoxynucelotidyl transferase-mediated deoxyuridine triphosphate nick end labeling; CCK-8;
The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation
Keywords: Trafficking; Endotubin; Rab; Tight Junction; Endosomes; AEC; apical endocytic complex; AP; alkaline phosphatase; CRISPR/Cas9; clustered regularly interspaced short palindromic repeats/cas9 endonuclease; EDTB; endotubin; EEA1; early endosomal antigen 1; G;
STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB
Keywords: STAT3; signal transducers and activators of transcription 3; RD-N; Riccardin D-N; CTSB; cathepsin B; LMP; lysosomal membrane permeabilization; LAMP1; lysosome associated membrane protein 1; LM-PCD; lysosomal-mediated programme of cell death; AO; acridine
Late diagnosis of mucopolysaccharidosis type IVB and successful aortic valve replacement in a 60-year-old female patient
Keywords: MPS IVB; mucopolysaccharidosis type IVB; GAGs; glycosaminoglycans; β-gal; acid β-galactosidase; LAMP1; lysosomal-associated membrane protein 1; SMA; smooth muscle actin; AVAi; aortic valve area index; PG; pressure gradient; VICs; valvular interstitial c
Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology
Keywords: AMPK; 5â²AMP-activated protein kinase; LRRK2; Leucine rich repeat kinase; LAMP1; Lysosomal associated membrane protein 1; iPD; idiopathic PD; mTOR; mammalian target of rapamycin; LC3; microtubule-associated protein1A/1B light chain 3; PD; Parkinson's d
Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice
Keywords: Fatty Liver; Gene Regulation; Hepatic Protection; Mouse Model; Ad; adenovirus; AH; alcoholic hepatitis; ALD; alcoholic liver disease; ALT; alanine aminotransferase; ATP6V0E1; ATPase H+ transporting V0 subunit E1; ATP6V1D; ATPase H+ transporting V1 subunit
Artesunate-induced mitophagy alters cellular redox status
Keywords: ACADVL; very long-chain specific acyl-CoA dehydrogenase; ACC; acetyl-CoA carboxylase 1; ATP; adenosine triphosphate, vacuolar-type H+-ATPase (V-ATPase); COX â
£; cytochrome c oxidase IV; CPS; carbamoyl-phosphate synthase; CQ; chloroquine; GSH; glutathione
Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation
Keywords: CHX; cycloheximide; EEA1; early endosome antigen 1; GA; geldanamycin; LAMP1; lysosomal-associated membrane protein 1; PMA; phorbol 12-myristate 13-acetate; RTK; receptor tyrosine kinase; ErbB2; Protein kinase C (PKC); Endocytosis; Endosomal sorting; Hsp90
Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease
Keywords: ATF4; activating transcription factor 4; BSA; bovine serum albumin; CHX; cycloheximide; CQ; hydroxychloroquine; HD; Huntington's disease; HDAC6; histone deacetylase 6; Htt; huntingtin; mHtt; mutant huntingtin; Lamp1; lysosomal associated membrane protein
Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview
Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C
Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state
Keywords: FFAs; free fatty acids; ROS; reactive oxygen species; MMP; mitochondrial membrane potential; GSH; glutathione; C/EBPα; CCAAT/enhancer binding protein α; PPARγ; peroxisome proliferator-activated receptor protein γ; SREBP-1c; sterol regulatory element-b
PCSK9-related LDL-C value is correlated to Rab5 isoform expression level
Keywords: CVD; cardiovascular diseases; TGN; trans-Golgi network; MPRs; mannose 6-phosphate receptors; PCSK9; proprotein convertase subtilisin/kexin type 9; LDLR; LDL receptor; LAMP1; lysosomal associated membrane protein 1; LAMP2; lysosomal associated membrane pro
Regulation of expression and trafficking of perforin-2 by LPS and TNF-α
Keywords: EEA1; early endosome antigen 1; ER; endoplasmic reticulum; LAMP1; lysosomal-associated membrane protein 1; MACPF; membrane-attack complex/perforin; PRF2a; perforin-2a; PRF2b; perforin-2b; TM; transmembrane; Mpeg1; MACPF domain; Transmembrane domain; Macro
ABCB1 2677G>T/A variant enhances chemosensitivity to anti-cancer agents acting on microtubule dynamics through LAMP1 inhibition
Keywords: ABCB1; Variant; Chemosensitivity; LAMP1;
The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition
Keywords: Cg; congenic; DMT1; divalent metal transporter 1; GFAP; glial fibrillary acidic protein; iba-1; ionized calcium-binding adapter molecule 1; LAMP1; lysosomal-associated membrane protein-1; Nramp1; natural resistance-associated macrophage protein-1; PD; Par
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Keywords: CHC; clathrin heavy chain; CHX; cycloheximide; DN; dominant negative; EEA1; early endosome antigen 1; ERAD; ER-associated degradation; ESCRT; endosomal sorting complex required for transport; Hrg; heregulin; ILVs; intra luminal vesicles; LAMP1; lysosome-a
Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
Keywords: AD; Alzheimer's Disease;; AGEs; advanced glycation endproducts; ALP; autophagy-lysosome pathway; ARF; alternate reading frame; ATGs; autophagy-related proteins; BAG3; Bcl2-associated athanogene 3; Bcl-2; B-cell lymphoma 2; BrdU; 5-bromodeoxyuridine;; CMA;
LAMP1 expression is associated with malignant behaviours and predicts unfavourable prognosis in laryngeal squamous cell carcinoma
Keywords: LAMP1; LSCC; qPCR; IHC; prognosis;
Biphasic effects of l-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells
Keywords: l-ascorbate; Non-thermal plasma (NTP); Reactive oxygen species (ROS); Autophagy; Mesothelioma; ANOVA; analysis of variance; DAPI; 4â²,6-diamidino-2-phenylindole; DFO; deferoxamine mesylate salt; EM; epithelioid mesothelioma; HBSS; Hanks' balanced salt
Riccardin D-N induces lysosomal membrane permeabilization by inhibiting acid sphingomyelinase and interfering with sphingomyelin metabolism in vivo
Keywords: RD-N; Riccardin D-N; LMP; lysosomal membrane permeabilization; ASM; acid sphingomyelinase; SM; sphingomyelin; CADs; cationic amphiphilic drugs; LAMP1; lysosome associated membrane protein 1; PARP; poly (ADP-ribose) polymerase; LDH; lactate dehydrogenase;
Exosomes and nanotubes: Control of immune cell communication
Keywords: APC; Antigen presenting cell; Cdc42; Cell division control protein 42; DC; Dendritic cell; EBV; Epstein-Barr virus; ESCRT; Endosomal sorting complex required for transport; HIV; Human immunodeficiency virus; ICAM-1; Intercellular adhesion molecule 1; IgA;
Ptaquiloside from bracken (Pteridium spp.) inhibits tumour-infiltrating CD8+ T cells in HPV-16 transgenic mice
Keywords: Ptaquiloside; Human papillomavirus; Cancer; Bracken; CD8+ T cells; BPV; Bovine Papillomavirus; CTL; Cytotoxic T Lymphocytes; FASL; FAS Ligand; FcγR; Fragment crystallisable gamma Receptor; H&E; Haematoxylin & Eosin; HPV; Human Papillomavirus; HSQC; Heter
CSF-1 receptor signalling is governed by pre-requisite EHD1 mediated receptor display on the macrophage cell surface
Keywords: CSF1R; colony stimulating factor 1 receptor; CSF1; colony stimulating factor-1; BMDM; bone marrow derived macrophage; EHD1; Eps-15 homology domain-containing protein 1; EHD1-KO; EHD1-knockout (4-hydroxytamoxifen induced deletion); RTK; receptor tyrosine k
The small GTPase Rab33A participates in regulation of amylase release from parotid acinar cells
Keywords: Rab33A; Parotid; Intracellular distribution; Amylase release; β-stimulation; APM; apical plasma membrane; BLM; basolateral plasma membrane; Cyto; cytosol; DAPI; 6-diamidino-2-phenylindole; EGTA; ethylene glycol-bis (β-aminoethyl ether)-N,N,Nâ²,Nâ²-tet
All-trans-retinoic acid and CD38 ligation differentially regulate CD1d expression and α-galactosylceramide-induced immune responses
Keywords: α-Galactosylceramide; CD1d; CD38; Retinoic acid; NKT cell; IL-4 production; IFNγ production; APC; antigen-presenting cell; αGalCer; α-galactosylceramide; DC; dendritic cell; LAMP1; lysosomal-associated membrane protein 1; NKT; natural killer T cell;
Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR
Keywords: mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo
T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice
Keywords: Cancer Immunotherapy; Tumor-Associated Antigens; Liver Cancer; Immune Response; E:T; effector to target cell ratio; GPC3; glypican-3; HCC; hepatocellular carcinoma; HLA; human leukocyte antigen; hTCM; human T-cell medium; IFN; interferon; IL; interleukin;
Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes
Keywords: microRNA-373; Non-small cell lung cancer; Histone deacetylase; Tumor suppressor; IRAK2; LAMP1
Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease
Keywords: β-gal; β-galactosidase; CtsD; cathepsin D; CD68; cluster of differentiation 68; GFAP; glial fibrillary acidic protein; Lamp1; lysosome-associated membrane protein 1; Lamp2; lysosome-associated membrane protein 2; MFSD8; major facilitator superfamily dom
Involvement of Ran in the regulation of phagocytosis against virus infection in S2 cells
Keywords: Ran; Ras related nuclear protein; Rab; Ras gene from rat brain; Rho; Ras homology; Arf; ADP-ribosylation factor; S2; Schneider line 2; PCR; polymerase chain reaction; DCV; Drosophila C virus; PMSF; phenylmethylsulfonyl fluoride; FITC; fluorescein isothioc
Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons
Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; EGCG; (â)-epigallocatechin-3-gallate; BAG2; BCL2-associated athanogene 2; LAMP1; lysosomal-associated membrane protein 1; NFTs; neurofibillary tangles; BACE1; beta-site APP cleaving enzyme-1; APP; amyloid prec
Lipopolysaccharide induces multinuclear cell from RAW264.7 line with increased phagocytosis activity
Keywords: LPS; lipopolysaccharide; iNOS; inducible nitric oxide synthase; TLR4; Toll-like receptor-4; RANKL; receptor activator of nuclear factor κB ligand; M-CSF; macrophage colony-stimulating factor; RANK; receptor activator of nuclear factor κB; FBGC; foreign
Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts
Keywords: ATG/Atg; autophagy-related gene; ATP6V0A1; encoding gene of isoform a1 of vacuolar H+-ATase V0 domain; H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; LAMP1; lysosomal-associated membrane protein 1; LC3; microtubule-associated-protein-light-chain
Mobility of late endosomal and lysosomal markers on phagosomes analyzed by fluorescence recovery after photobleaching
Keywords: Fluorescence recovery after photobleaching; IFN-γ; LAMP1; Mycobacterium bovis BCG; Phagosome; Rab7;
Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: A key role for hRFT-2 in intestinal riboflavin uptake
Keywords: LAMP1; lysosome associated membrane protein1; Transport; Intestine; Epithelia; Polarity; Targeting;
Mammalian ER stress sensor IRE1β specifically down-regulates the synthesis of secretory pathway proteins
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; hIRE1; human inositol-requiring enzyme 1; hPERK; human PKR-like endoplasmic reticulum kinase; FBLN1; fibulin 1; B2M; beta-2-microglobulin; FBN1; fibrillin 1; CD59; CD59 molecule, complement regula
Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
Keywords: ANOVA; analysis of variance; mTOR; mammalian target of rapamycin; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; ER; endoplasmic reticulum; GFP; green fluorescent protein; LC3; microtubule-associated protein light chain 3; LT
Differential, Type I Interferon-Mediated Autophagic Trafficking of Hepatitis C Virus Proteins in Mouse Liver
Keywords: Autophagy; TLR3; Liver Disease; RIG-I; AdLacZ; recombinant adenovirus LacZ; ER; endoplasmic reticulum; HCV; hepatitis C virus; IFN; interferon; IRF-3; IFN regulatory factor-3; ISG; IFN-stimulated gene; LAMP1; lysosome-associated membrane protein 1; LC3B;
A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis
Keywords: TPD52; Tumor protein D52; VAMP 8; vesicle associated membrane protein 8; SNARE; soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor; LAMP1; lysosome associated membrane protein; HA; hemagglutinin; pfu; plaque forming units; Tumor
Brefeldin A inhibits vesicular MHC class I processing in resting but not in CpG- and disruption-activated DC
Keywords: DC, dendritic cells; VP, vesicular MHC class I processing; BFA, Brefeldin A; OVA, ovalbumin; Cat S, cathepsin S; LAMP1, lysosomal-associated membrane protein 1DC; Vesicular MHC-I processing; TLR; Cat S; LAMP1