VEGF- and LPA-induced telomerase in human ovarian cancer cells is Sp1-dependent
Keywords: Telomerase; VEGF; LPA; MAPK; Ovarian cancer; Sp1; hTERT
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MAP1B coordinates microtubule and actin filament remodeling in adult mouse Schwann cell tips and DRG neuron growth cones
Keywords: Microtubule-associated protein 1B; Retraction; Migration; Actin–myosin; LPA; Rho/ROCK signalization; Motility
The Lysophosphatidic Acid Type 2 Receptor Is Required for Protection Against Radiation-Induced Intestinal Injury
Keywords: BrdU; bromodeoxyuridine; BSA; bovine serum albumin; CHX; cycloheximide; EDG; endothelial differentiation gene; ERK; extracellular signal-regulated kinase; KO; knockout; LPA; lysophosphatidic acid; LPP; lipid phosphate phosphatase; MEK; mitogen-activated
Hypothesis: VPAC G protein-coupled receptors for vasoactive intestinal peptide constitute a dynamic system for signaling T cells from plasma membrane and nuclear membrane complexes
Keywords: VIP; vasoactive intestinal peptide; GPCR; G protein-coupled receptor; VPAC1; type 1 VIP receptor; VPAC2; type 2 VIP receptor; T cell; T lymphocyte; LPA; lysophosphatidic acid; S1P; sphingosine 1-phosphate; LPA1; type 1 LPA receptor; iNOS; inducible nitric
K-shell ionization of low Z elements in ion-solid collisions and applicability of local plasma approximation
Keywords: Inner shell ionization; ECPSSR; LPA;
Lysophosphatidic acid stimulates inflammatory cascade in airway epithelial cells
Keywords: CHES; chronic hyperplastic eosinophilic sinusitis; EGF; epidermal growth factor; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; granulocyte macrophage-colony stimulating factor;
Lysophosphatidic Acid (LPA)-Induced Vascular Endothelial Growth Factor (VEGF) by Mesothelial Cells and Quantification of Host-Derived VEGF in Malignant Ascites
Keywords: mesothelial cell; LPA; VEGF; host-derived; ascites
Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands
Keywords: LPA; Phosphatidic acid; Autotaxin
S1P regulation of ovarian carcinoma invasiveness
Keywords: S1P; LPA; Ovarian cancer; Invasion; S1P receptors; LPA receptors
Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts
Keywords: Cardiac fibroblasts; LPA; Proliferation; Apoptosis; Receptor; Caspase-3; Cell viability; Mitochondrial dysfunction
Ligand density and integrin repertoire regulate cellular response to LPA
Keywords: Fibronectin; Integrin; LPA; Rho
Purification and characterization of lysophospholipase D from rat brain
Keywords: ATX; autotaxin; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]propanesulfonic acid; DTT; Dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EDG; endothelial differentiation genes; GPC; glycerophosphorylcholine; GP; glycerophosphate; LPA; lysophosphatid
Impaired Power Output and Cardiac Index With Hypoplastic Left Heart Syndrome: A Magnetic Resonance Imaging Study
Keywords: AL; anterior left; AR; anterior right; BSA; body surface area; CHOA; Children's Healthcare of Atlanta; CHOP; Children's Hospital of Philadelphia; HLHS; hypoplastic left heart syndrome; LPA; left pulmonary artery; PC MRI; phase contrast magnetic resona
Serine phosphorylation differentially affects RhoA binding to effectors: Implications to NGF-induced neurite outgrowth
Keywords: Rho; Differentiation; Phosphorylation; PC12; LPA;
Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells
Keywords: DMSO; dimethyl sulphoxide; EYFP; enhanced yellow fluorescent protein; FBS; fetal bovine serum; GPCR; G-protein coupled receptor; GST; glutathione-s-transferase; HA3; triple hemagglutinin epitope tag; IBMX; 3-isobutyl-1-methylxanthine; InsP3; inositol-1,4,
Lipids and lipid metabolism in eukaryotic algae
Keywords: AA; arachidonic acid (C20:4n-6); APCI-MS; atmospheric pressure chemical ionization mass spectrometry; ASQD; 2â²-O-acyl-sulfoquinovosyldiacylglycerol; BTA1Cr; betaine lipid synthase (from Chlamydomonas reinhardtii); DAG; diacylglycerol; DGCC; diacylglycer
Simultaneous management of congenital tracheal stenosis and cardiac anomalies in infants
Keywords: 15; 20; 25; ASD; atrial septal defect; AVSD; atrioventricular septal defect; CPB; cardiopulmonary bypass; CTS; congenital tracheal stenosis; LPA; left pulmonary artery; PA; pulmonary artery; VSD; ventricular septal defect;
Lysophospholipids in the nervous system
Keywords: Lysophosphatidic acid; Lysophosphatidylcholine; Sphingosine 1-phosphate; Neuroscience; G protein-coupled receptor; LPA; S1P;
Lysophosphatidic acid increases phosphatidic acid formation, phospholipase D activity and degranulation by human neutrophils
Keywords: Lysophosphatidic acid; Phosphatidic acid; Phospholipase D; Degranulation; Neutrophils (human); LPA; lysophosphatidic acid; PA; phosphatidic acid; PLD; phospholipase D; PLC; phospholipase C; PIP2; phosphatidylinositol 4,5-bisphosphate; PC; phosphatidylchol
Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells
Keywords: BrdU; 5-bromo-2â²-deoxy-uridine; DMEM; Dulbecco's modified Eagle medium; EDTA; ethylenediaminetetraacetate; EGCG; epigallocatechin-3-gallate; FAK; focal adhesion kinase; FCS; fetal-calf serum; GDP; guanosine diphosphate; GTP; guanosine triphosphate; HS
Application of matrix-assisted laser desorption and ionization time-of-flight mass spectrometry for the characterization of the substrate specificity of neutrophil phospholipase A2
Keywords: DHB-2,5; Dihydroxybenzoic acid; ESI; Electrospray ionisation; FAB; Fast-atom bombardment; FFA; Free fatty acid; fMLP; N-formyl-l-methionyl-l-leucyl-l-phenylalanine; HBSS; Hank's balanced salt solution; LPA; Lysophosphatidic acid; LPC; Lysophosphatidylchol
Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development
Keywords: CP; cortical plate; DCP; dense cortical plate; DT; dorsal thalamus; ET; epithalamus; IZ; intermediate zone; LPA; lysophosphatidic acid; LPPs; lipid phosphate phosphohydrolases; MGN; medial geniculate nucleus; MZ; marginal zone; PA; phosphatidic acid; PCR;
A novel oligodendrocyte cell line OLP6 shows the successive stages of oligodendrocyte development: Late progenitor, immature and mature stages
Keywords: Edg-2/LPA1; lysophosphatidic acid; myelination; oligodendrocyte cell line; survival; temperature-sensitive simian virus 40 T-antigen; CNPase; 2â²-3â²-cyclic-nucleotide 3â²-phosphodiesterase; Edg-2/LPA1; endothelial differentiation gene receptor-2; FBS;
Comparison of three assays for the evaluation of specific cellular immunity to Leishmania infantum in dogs
Keywords: IFNB; IFN-γ cytopathic effect inhibition bioassay; LPA; lymphocyte proliferation assay; LSA; Leishmania infantum soluble antigen; LST; leishmanin skin test; Dog; Leishmania infantum; Cellular immune response; Lymphocyte proliferation; Interferon-γ; Leis
Lysophosphatidic acid mediates pleiotropic responses in skeletal muscle cells
Keywords: Skeletal muscle cells; LPA; MAP kinase; Caspase 3; Cell viability;
Active p21-Activated Kinase 1 Rescues MCF10A Breast Epithelial Cells from Undergoing Anoikis
Keywords: Breast carcinoma; apoptosis; cell survival; caspase activation; protein kinases; EGF; epidermal growth factor; ECM; extracellular matrix; GPCR; G proteincoupled receptor; HA; hemagglutinin; LPA; lysophosphatidic acid; PAK; p21-activated kinase; PARP; poly
A Gβγ inhibitor reduces intimal hyperplasia in aortocoronary saphenous vein grafts
Keywords: Ad; adenovirus; AdGFP; adenoviruses containing the coding sequence for the green fluorescent protein; ANOVA; analysis of variance; βARK1; β-adrenergic receptor kinase 1; CABG; coronary artery bypass grafting; DNA; deoxyribonucleic acid; EGF; epidermal g
Reduced LPA expression after peroxisome proliferator-activated receptor alpha (PPARα) activation in LPA-YAC transgenic mice
Keywords: LPA; Apo(a); Transgenic mice; Fibrates;
Evidence for a different metabolism of PC and PE in shoots and roots
Keywords: Roots; Shoots; Lipid acylation; Phosphatidylcholine; Phosphatidylethanolamine; AAPT; amino-alcohol phosphotransferase; CCT; choline citidylyltransferase; CDP; cytidine diphosphate; CHO; choline; CK; choline kinase; CoA; coenzyme A; DAG; diacylglycerol; DM
Investigating serum factors promoting erythrocytic growth of Plasmodium falciparum
Keywords: ALB; albumin; ANOVA; multifactorial analysis of variance; BSAF; NEFA-free ALB from bovine; C16:0; hexadecanoic acid; C16:1; cis-9-hexadecenoic acid; C18:0; octadecanoic acid; C18:1; cis-9-octadecenoic acid; C18:2; cis,cis-9,12-octadecadienoic acid; C18:3;
The importance of standardisation of laboratory evaluations in HIV vaccine trials
Keywords: Standardisation; Assay; Immunological response; Vaccine; APC; antigen presenting cell; AVIP; AIDS Vaccine Integrated Project; CAF; CD8 anti-viral factor; CASA; CD8 anti-HIV suppressor activity; CBA; cytometric bead array; CFSE; carboxyfluorescein diacetat
LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA1/Egr-1 axis
Keywords: LPA; EGF receptor; Egr-1; Bone; Periostin; MAPK;
A DNA HIV-1 vaccine based on a fusion gene expressing non-structural and structural genes of consensus sequence of the A-C subtypes and the ancestor sequence of the F-H subtypes. Preclinical and clinical studies
Keywords: HIV vaccine; MultiHIV; BPV; bovine papilloma virus; CMV; cytomegalovirus; CTL; cytotoxic T lymphocyte; EP; electroporation; g.g.; gene gun; GTU®; Gene Transport Unit; HAART; highly active anti-retroviral therapy; i.d.; intradermal; IFN-γ; interferon-gam
Idiopathic intracranial hypertension, polycystic-ovary syndrome, and thrombophilia
Keywords: ACLA; anticardiolipin antibody; APTT; activated partial thromboplastin time; BMI; body-mass index (kilograms per square meter); CSF; cerebrospinal fluid; DHEAS; dehydroepiandrosterone sulfate; DRVVT; dilute Russel's viper venom time; EDTA; ethylenediami
Sphingosylphosphorylcholine generates reactive oxygen species through calcium-, protein kinase Cδ- and phospholipase D-dependent pathways
Keywords: SPC; sphingosylphosphorylcholine; GPCRs; G protein-coupled receptors; PLC; phospholipase C; PIP2; phosphatidylinositol 4, 5-bisphosphate; [Ca2+]i; intracellular Ca2+; PLD; phospholipase D; LPA; lysophosphatidic acid; PKC; protein kinase C; ARF; ADP-ribosy
Evidences that β1 integrin and Rac1 are involved in the overriding effect of laminin on myelin-associated glycoprotein inhibitory activity on neuronal cells
Keywords: MAG; myelin-associated glycoprotein; PLL; poly-l-lysine; NGF; neuronal growth factor; ECM; extracellular matrix; LPA; lysophosphatidic acid;
Rhythms of glycerophospholipid synthesis in retinal inner nuclear layer cells
Keywords: DD; constant darkness; LL; constant light; LD; light-dark; DAG; diacylglycerol; DGL; diacylglycerol lipase; INL; inner nuclear layer; LPA; lysophosphatidic acid; IPL; inner plexiform layer; LPC; lysophosphatidylcholine; LPE; lysophosphatidylethanolamine
Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway
Keywords: BCECF; 2â²,7â²-bis-(carboxyethyl)-5-(and-6)-carboxyfluorescein; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; KI-MEK1; kinase inactive MAP kinase/ERK kinase 1; LPA; lysophosphatidic acid; NHE1; sodium hydrogen exchanger
p85 β-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase
Keywords: LPA; lysophosphatidic acid; PAK; p21 activated kinase; PID; PAK inhibitory domain; PIX; PAK-interacting exchange factor; GIT1; G-protein-coupled receptor kinase interacting targets; bFGF; basic fibroblast growth factor; FAK; focal adhesion kinase; LysoPLD
c-Src is involved in regulating signal transmission from PDGFβ receptor-GPCR(s) complexes in mammalian cells
Keywords: ASM; airway smooth muscle; CHO; Chinese hamster ovary; Con A; concanavalin A; Gi; inhibitory G protein; Giα; alpha sub-unit of Gi; Gab1; Grb-2 associated binder-1; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; Grb-2; growth fa
The duration of in vitro stimulation with recall antigens determines the subset distribution of interferon-γ-producing lymphoid cells: A kinetic analysis using the Interferon-γ Secretion Assayâ¢
Keywords: BC; buffy coat; CTL; cytotoxic T lymphocyte; Elisa; enzyme-linked immunosorbent assay; Elispot; enzyme-linked immunospot; FACS; fluorescence activated cell sorter; HBsAg; hepatitis B surface antigen; IC; intracellular cytokine staining; IFNγ; interferon-
PKB mediates c-erbB2-induced epithelial β1 integrin conformational inactivation through Rho-independent F-actin rearrangements
Keywords: ca; constitutively active; dn; dominant-negative; ERK; extracellular signal-regulated kinase; GFP; green fluorescent protein; GST; glutathione-S-transferase; ILK; integrin-linked kinase; LPA; lysophosphatidic acid; LTB; latrunculin B; mDia; mammalian ho
Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing
Keywords: AEA; anandamide; DNBS; dinitrobenzene sulphonic acid; ERK; extracellular-regulated kinase; FAAH; fatty acid amide hydrolase; GSK; glycogen synthase kinase; LPA; lysophosphatidic acid; MAPK; mitogen-activated protein kinase; NE; noladin ether; PI3K; phosph
Potential oncogenic action of tenascin-C in tumorigenesis
Keywords: ALK; anaplastic lymphoma kinase; Bardl; BRCA1-associated ring finger domain protein; KDdissociation constant; CASK; calmodulin-associated serine/threonine kinase; cdk; cyclin dependent kinase; CHAF1; chromatin assembly factor 1; CKI; cdk inhibitor; DKK1;