Hypothalamic Kiss1 and RFRP gene expressions are changed by a high dose of lipopolysaccharide in female rats
Keywords: Stress; LPS; Kisspeptin; Kiss1; RFRP; GPR147; GnRH;
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Blockade of PDE4B limits lung vascular permeability and lung inflammation in LPS-induced acute lung injury
Keywords: PDE4B; Acute lung injury; LPS; Vascular barrier dysfunction;
The effects of LPS on adhesion and migration of human dental pulp stem cells in vitro
Keywords: LPS; hDPSCs; Adhesion; Migration; NF-κB; MAPK;
Toll like receptors in self-recovering hepatitis E patients with or without pregnancy
Keywords: ANC; Antenatal care (pregnancy); HEV; hepatitis E virus; TLR; Toll like receptors; IRAK; interleukin-1 receptor-associated kinase; IkBα; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; NFkB; nuclear factor kappa-light
p38 Mitogen-Activated Protein Kinase in beryllium-induced dendritic cell activation
Keywords: DCs; CBD; Lymphocyte proliferation; p38MAPK; NF-κB; APCs; antigen presenting cells; Be; beryllium; BeLPT; Be lymphocyte proliferation test; BeS; Be sensitized; CBD; chronic beryllium disease; DCs; dendritic cells; iDCs; Immature Dendritic cells; ERKs; ex
Research ReportBrain capillary pericytes contribute to the immune defense in response to cytokines or LPS in vitro
Keywords: Pericytes; Cytokines; Inflammation; LPS; Macrophage-like phenotype;
Research reportOverexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: Modulation by NOS inhibitors
Keywords: Alzheimer; Nitric oxide; NMDAR; NOS inhibitors; Diflunisal; LPS;
Research ReportProstaglandin E2 induces apoptosis in cultured rat microglia
Keywords: AMP; adenosine monophosphate; ATP; adenosine triphosphate; DNA; deoxyribonucleic acid; EDTA; 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; LDH; lactate dehydrogenase; LPS; lipopolys
Research ArticleGenetic variation in TNFA predicts protection from severe bacterial infections in patients with end-stage liver disease awaiting liver transplantation
Keywords: SBI; severe bacterial infections; ESLD; end-stage liver disease; OLT; orthotopic liver transplantation; TLR; toll-like receptors; TLR4; toll-like receptor 4; LPS; lipopolysaccharide; SNP; single nucleotide polymorphism; TNF-α; tumour necrosis factor-alph
Research ArticleNod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids
Keywords: NASH; non-alcoholic steatohepatitis; Nod; nucleotide oligomerization domain; MDP; muramyl dipeptide; IL; interleukin; BDL; bile duct ligation; ALT; alanine aminotransferase; ALP; alkaline phosphatase; TNF; tumor necrosis factor; LPS; lipopolysaccharide; C
β2-glycoprotein I, lipopolysaccharide and endothelial TLR4: Three players in the two hit theory for anti-phospholipid-mediated thrombosis
Keywords: β2-Glycoprotein I; Anti-β2-glycoprotein I antibodies; Toll-like receptor 4; Endothelial cells; LPS; Innate immunity;
Degraded λ-carrageenan activates NF-κB and AP-1 pathways in macrophages and enhances LPS-induced TNF-α secretion through AP-1
Keywords: CGN, Carrageenan; λ-dCGN, Degraded λ-carrageenan; JECFA, Joint FAO/EHO Expert Committee on Food Additives; NOSB, National Organic Standards Board; CCTCC, China Center for Type Culture CollectionDegraded λ-carrageenan (λ-dCGN); LPS; TLR4; NF-κB; AP-1
Research reportEffects of chemokine receptor signalling on cognition-like, emotion-like and sociability behaviours of CCR6 and CCR7 knockout mice
Keywords: EAE; autoimmune encephalomyelitis; 3ÃTg AD; triple transgenic Alzheimer's disease; LPS; lipopolysaccharide; KO; knockout; NORT; novel object recognition test; EZM; Elevated Zero Maze; FST; forced swim test; PFC; prefrontal cortex; CCR6; CCR7; Cognition;
Frequency of regulatory T-cell and hepatitis C viral antigen-specific immune response in recurrent hepatitis C after liver transplantation
Keywords: ALT; alanine aminotransferase; CHC; chronic hepatitis C; DC; dendritic cell; ELISPOT; enzyme-linked immunosorbent spot; FITC; fluorescein isothiocyanate; FOXP3; forkhead box P3; HCV; hepatitis C virus; IL; interleukin; IFN; interferon; LPS; lipopolysaccha
Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells
Keywords: ASA; acetylsalicylic acid; DMEM; Dulbecco's modified Eagle medium; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked immunosorbent assay; ERK1/2; extracellular-regulated kinase 1/2; FBS; fetal bovine serum; FLX; fluoxetine; IDO; indoleamine 2,
Circadian cycle-dependent EEG biomarkers of pathogenicity in adult mice following prenatal exposure to in utero inflammation
Keywords: ADHD; attention-deficit hyperactivity disorder; EEG; electroencephalogram; EMG; electromyogram; LPS; lipopolysaccharide; NREM; non-rapid eye movement; PBS; phosphate-buffered saline; PND; postnatal day; qEEG; quantitative electroencephalogram; TNFα; tumo
UHPLC profiling and effects on LPS-stimulated J774A.1 macrophages of flavonoids from bergamot (Citrus bergamia) juice, an underestimated waste product with high anti-inflammatory potential
Keywords: Bergamot; Flavonoids; UHPLC; LPS; Inflammation;
Inhibitory effects of Pleurotus tuber-regium mycelia and bioactive constituents on LPS-treated RAW 264.7 cells
Keywords: cDNA; complementary DNA; COX2; cyclooxygenase 2; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immunosorbent assay; EtOAc; ethyl acetate; FBS; fetal bovine serum; IL; interleukin; iNOS; inducible NOS; LPS; lipopolysaccharide; MTT; 3-(
Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages
Keywords: AP-1; activator protein-1; HMGB1; high-mobility-group box 1; IKK; IκB kinase; iNOS; inducible nitric oxide synthase; IL-1β; interleukin-1β; IL-6; interleukin-6; LPS; lipopolysaccharide; NF-κB; nuclear factor-κB; O2â; superoxide anion; OA; osteoarth
Subcutaneous inverse vaccination with PLGA particles loaded with a MOG peptide and IL-10 decreases the severity of experimental autoimmune encephalomyelitis
Keywords: BCA; bicinchoninic acid; CHOs; Chinese hamster ovary cells; CNS; central nervous system; CTL; cytotoxic T lymphocytes; DCM; dichloromethane; DLS; dynamic light scattering; EAE; experimental autoimmune encephalomyelitis; FDA; food and drug administration;
Reciprocal interaction between the suprachiasmatic nucleus and the immune system tunes down the inflammatory response to lipopolysaccharide
Keywords: BBB; blood brain barrier; COX2; cyclooxygenase 2; CVOs; circumventricular organs; CRH; corticotropin releasing hormone; IFNγ; interferon γ; IL-6; interleukin 6; iv; intravenous; LD; light-dark; LPS; lipopolysaccharide; PVN; paraventricular nucleus; TL
Isotetrandrine protects against lipopolysaccharide-induced acute lung injury by suppression of mitogen-activated protein kinase and nuclear factor-kappa B
Keywords: Isotetrandrine (ITD); LPS; Inflammation; ALI
FLLL31, a derivative of curcumin, attenuates airway inflammation in a multi-allergen challenged mouse model
Keywords: STAT; signal transducer and activator of transcription; JAK; Janus kinase; LPS; lipopolysaccharide; Con A; concanavalin A; HDM; house dust mite; PBS; phosphate-buffered saline; NO; nitric oxide; Dex; dexamethasone; TNF-α; tumor necrosis factor α; IL; in
The total alkaloids of Aconitum tanguticum protect against lipopolysaccharide-induced acute lung injury in rats
Keywords: TAA; total alkaloids of Aconitum tanguticum; AC; aconitine; HDTAA; high dose of TAA; LDTAA; low dose of TAA; ALI; acute lung injury; LPS; lipopolysaccharide; H-E; hematoxylin-eosin; BALF; bronchoalveolar lavage fluid; TNF-α; tumor necrosis factor-alp
Toll-like receptor 4-mediated ROS signaling pathway involved in Ganoderma atrum polysaccharide-induced tumor necrosis factor-α secretion during macrophage activation
Keywords: ATCC; American Type Culture Collection; CM-DCFH; carboxyl-DCFH; CR3; complement receptor 3; FBS; fetal bovine serum; HRP; horseradish peroxidase; IKK; IκB kinase; IRAK; interleukin-1 receptor associated kinase; LPS; lipopolysaccharide; MAPKs; mitogen-act
Gomisin A inhibits lipopolysaccharide-induced inflammatory responses in N9 microglia via blocking the NF-κB/MAPKs pathway
Keywords: Gomisin A; Microglia; LPS; NF-κB; MAPKs; ROS;
Possible hepatocellular toxicity of EGCG under the influence of an inflammagen
Keywords: Green tea; EGCG; LPS; Inflammation; Hepatotoxicity
Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1
Keywords: E. coli; Escherichia coli; G-CSF; granulocyte-colony stimulating factor; JAK2; janus kinase 2; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinases; MDDC; monocyte-derived dendritic cells; NLRP3; NLR-family, pyrin containing 3; PAMPs; pathogen
Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway
Keywords: AP; action potential; APD; action potential duration; DAD; delayed after depolarization; IRAK1/4; interleukin-1 receptor-associated kinase 4; IRF3; interferon regulatory factor 3; Ito; transient outward potassium current; KChIP2; Kv channel-interacting pr
Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4
Keywords: S1P; sphingosine 1-phosphate; GPCR; G-protein-coupled receptor; S1P1; sphingosine 1-phosphate receptor type 1 (EDG1); LPS; lipopolysaccharide; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase 2; NF-κB; nuclear factor kappa B; STAT6; signal tr
2-Arachidonoylglycerol modulates human endothelial cell/leukocyte interactions by controlling selectin expression through CB1 and CB2 receptors
Keywords: Endocannabinoids; Endothelium/leucocyte interaction; TNF-α; Kinases; Selectins; ABHD6; α/β-hydrolase domain 6; APC; allophycocyanin; 2-AG; 2-Arachidonoylglycerol; DAPI; 4â²,6-diamidino-2-phenylindole; CB1; type-1 cannabinoid receptor; CB2; type-2 cann
LL-37 attenuates inflammatory impairment via mTOR signaling-dependent mitochondrial protection
Keywords: EGFP; enhanced green fluorescent protein; qRT-PCR; quantitative reverse transcription PCR; LPS; lipopolysaccharides; NC-siRNA; negative control small interfering RNA; PGC-1α; PPAR-γ co-activator-1α; PPAR; peroxisome proliferator-activated receptor; ERK
The phospholipase D pathway mediates the inflammatory response of the retinal pigment epithelium
Keywords: ARPE-19 cells; Retinal pigment epithelium (RPE); Inflammation; Phospholipase D (PLD); Cyclooxygenase-2; AA; arachidonic acid; AMD; age-related macular degeneration; COX; cyclooxygenase; DAG; diacylglycerol; DR; diabetic retinopathy; EGFP; enhanced green f
Lipopolysaccharide induces the interactions of breast cancer and endothelial cells via activated monocytes
Keywords: Breast cancer; Metastasis; LPS; Histamine; Monocyte;
MafB is a downstream target of the IL-10/STAT3 signaling pathway, involved in the regulation of macrophage de-activation
Keywords: EMSA; electrophoretic mobility shift assay; HSCs; hematopoietic stem cells; IL-7R; Interleukine 7 Receptor; LPS; lipopolysaccharides; MARE; Maf responsive element; MMP9; Matrix Metalloproteinase 9; PMA; phorbol 12-myristate 13-acetate; QRT-PCR; quantitati
Glutathione transferase Omega 1 is required for the lipopolysaccharide-stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages
Keywords: GCL; glutamate-cysteine ligase; GSH; glutathione; GPx3; glutathione peroxidase 3; GR; glutathione reductase; GST; glutathione transferase; IκκB; inhibitor of nuclear factor κB kinase; LPS; lipopolysaccharide; MyD88; myeloid differentiation primary re
Chronic social instability stress enhances vulnerability of BDNF response to LPS in the limbic structures of female rats: A protective role of antidepressants
Keywords: BDNF; brain derived neurotrophic factor; CAM-L1; cell adhesion molecule-L1; CNS; central nervous system; CREB; cAMP response element-binding protein; CSIS; chronic social instability stress; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GR; glucocortic
Immobilizing live Escherichia coli for AFM studies of surface dynamics
Keywords: AFM; Atomic Force Microscopy; OMVs; outer membrane vesicles; PLL; α-Poly-l-lysine; LB; Luria Bertani; MM; minimal media; MM+; minimal media with 0.05% protein hydrolysate amicase; PBS-S; supplemented PBS; LPS; lipopolysaccharide; Atomic Force Microscopy
Arylnitroalkenes as scavengers of macrophage-generated oxidants
Keywords: Nitroalkenes; Peroxynitrite; Nitric oxide; Nitrogen dioxide; Scavengers; Antioxidants; RS; reactive species; NO2-FA; nitro-fatty acids; LPS; lipopolysaccharide; Fe2+-Cyt c; Fe2+-cytochrome c; Fe3+-Cyt c; Fe3+-cytochrome c; DHR; dihydrorhodamine; RH; rhoda
Prenatal lipopolysaccharide disrupts maternal behavior, reduces nest odor preference in pups, and induces anxiety: Studies of F1 and F2 generations
Keywords: Prenatal inflammation; LPS; Maternal care; Maternal aggressive behavior;
Brain protein expression changes in WAG/Rij rats, a genetic rat model of absence epilepsy after peripheral lipopolysaccharide treatment
Keywords: Brain proteomics; Epilepsy; Inflammation; LPS; NFkB; Sleep-wake cycle;
Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1
Keywords: Ms-EE; ethanolic extract of Myrsine seguinii; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; (TNF)-α; tumour necrosis factor; ERK; extracellular signal-related kinase; TLR; toll-like receptors (TLR); MAPK; mit
The neuroprotective effect of modified “Shengyu” decoction is mediated through an anti-inflammatory mechanism in the rat after traumatic brain injury
Keywords: GFAP; glial fibrillary acidic protein; Iba1; ionized calcium binding adapter molecule-1; IL-6; interleukin-6; IL-10; interleukin-10; IL-1β; interleukin-1β; LPS; lipopolysaccharide; MSD; modified “Shengyu” decoction; No; nitric oxide; RAGE; receptor
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages
Keywords: RAW264.7 mouse macrophage cell line; Suppressors of cytokine signaling1 (SOCS1); Hypermethylation; DNA methyltransferase1 (DNMT1); Pro-inflammatory cytokines; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin 6; SOCS; suppressor
Cigarette-smoke-induced priming of neutrophils from smokers and non-smokers for increased oxidative burst response is mediated by TNF-α
Keywords: ANOVA; analysis of variance; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; FCS; fetal calf serum; fMLP; N-formyl-methionyl-leucyl-phenylalanine; GM-CSF; granulocyte-macrophage colony-stimulating factor; IL; interleukin; LPS; lipopolysa
Early events in Sjögren's Syndrome pathogenesis: The importance of innate immunity in disease initiation
Keywords: ANA; anti-nuclear autoantibodies; BAFF; B cell activating factor; DAMP; danger associated molecular pattern; ECM; extracellular matrix; FLS; focal lymphocytic sialoadenitis; HS; heparan sulfate; HSPG; heparan sulfate-proteoglycan; LPS; lipopolysaccharide;
Galleria mellonella native and analogue peptides Gm1 and ÎGm1. I) Biophysical characterization of the interaction mechanisms with bacterial model membranes
Keywords: AMPs; Antimicrobial peptides; Gm; Galleria mellonella; DMPG; dimyristoylphosphatidylglycerol; DMPE; dimyristoylphosphatidylethanolamine; FTIR; Fourier-transform infrared spectroscopy; FRET; Förster resonance energy transfer spectroscopy; DSC; differentia
Resveratrol enhances TNF-α production in human monocytes upon bacterial stimulation
Keywords: FLA; flagellin; GAPDH; glyceraldehyde 3 phosphate dehydrogenase; IL; interleukin; LPS; lipolysaccharide; MAPK; mitogen activated protein kinase; NF-κB; nuclear factor 'kappa-light-chain-enhancer' of activated B-cells; PBMC; peripheral blood mononucle
Regular ArticleA pivotal role of nonmuscle myosin II during microglial activation
Keywords: ELC; essential light chain; LPS; lipoplysaccharide; MLCK; myosin light chain kinase; NM II; nonmuscle myosin II; NO; nitric oxide; RLC; regulatory light chain; ROCK; Rho kinase; TNFα; tumor necrosis factor α; Neuroinflammation; Microglial response; Cyto
Original ResearchFull Report: Basic and Translational-Alimentary TractEndotoxicity of Lipopolysaccharide as a Determinant of T-CellâMediated Colitis Induction in Mice
Keywords: Mouse Model; IBD; Prevention; Bacteria; clp; colonic lamina propria; DC; dendritic cell; DSS; dextran sodium sulfate; IBD; inflammatory bowel disease; IL; interleukin; LPS; lipopolysaccharide; MHC; major histocompatibility complex; MUT; mutant; rDNA; ribo