Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53
Keywords: Autoantibody; Lupus; Apoptosis; mAb; monoclonal antibody;
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A new format of bispecific antibody: highly efficient heterodimerization, expression and tumor cell lysis
Keywords: BsAb; bispecific antibody; CH2 and CH3; constant region 2 and 3 of immunoglobulin heavy chain; DHFR; dihydrofolate reductase; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; Fv; variable fragment of antib
Fractalkine gene therapy for neuroblastoma is more effective in combination with targeted IL-2
Keywords: Fractalkine; GD2; Ch14.18-IL-2; Neuroblastoma; Gene therapy; Immunotherapy; mFKN; murine fractalkine; IL; interleukin; GD2; disialoganglioside GD2; mAb; monoclonal antibody; NB; neuroblastoma; s.c.; subcutaneous; i.v.; intravenous; NK; natural killer;
Treatment of Ischemic Limbs Based on Local Recruitment of Vascular Endothelial Growth Factor-Producing Inflammatory Cells With Ultrasonic Microbubble Destruction
Keywords: mAb; monoclonal antibody; T-PBS; phosphate-buffered saline with 0.2% Tween; US/MB; ultrasonic destruction of microbubbles; VEGF; vascular endothelial growth factor; VGF(s); vascular growth factor(s);
Non-enzymatic hinge region fragmentation of antibodies in solution
Keywords: MAb; monoclonal antibody; SEC; size-exclusion chromatography; HC; heavy chain; LC; light chain; CHOP; Chinese hamster ovary cell protein; LC-ESI/MS; liquid chromatography-electrospray mass spectrometry; HPLC; high performance liquid chromatography; Da; Da
Senile seminal vesicle amyloid is derived from semenogelin I
Keywords: ABTS; 2,2â²-azino-di-3-ethyl-benzthiazoline sulfonic acid; AEC; 3-amino-9-ethyl-carbozol; HPLC; high-performance liquid chromatography; mAb; monoclonal antibody; MS-MS; tandem mass spectrometry; PAP; peroxidase-antiperoxidase; SDS/PAGE; sodium dodecyl su
Sensing cell stress and transformation through Vγ9Vδ2 T cell-mediated recognition of the isoprenoid pathway metabolites
Keywords: Immunology; T lymphocytes; Gamma/delta T cell receptor; Isoprenoid biosynthesis; ABP; aminobiphosphonate; Ag; antigen; ApoA1; apolipoprotein A1; AS; ATP synthase; DC; dendritic cell; DMAPP; dimethylallyl pyrophosphate; DOXP; 1-deoxy-d-xylulose-5-phosphate
Soluble chemokine CCR5 receptor is present in human plasma
Keywords: sCCR5; soluble chemokine receptor CCR5; HIV; human immunodeficiency virus; mAb; monoclonal antibody; ECL; extracellular loop; PBMC; peripheral blood mononuclear cells; RT-PCR; reverse trascriptase-polymerase chain reaction; M-MLV RT; moloney murine leukem
Biological inactivation and impaired detection of IL-10 by suramin
Keywords: DTT; dithiothreitol; ELISA; enzyme-linked immunosorbent assay; IL-10; interleukin-10; IL-12p40; interleukin-12p40; LPS; lipopolysaccharide; MAB; monoclonal antibodies; PDGF; platelet derived growth factor; rhIL-10; recombinant human IL-10; TNF-alpha; tumo
Liposomes targeted via two different antibodies: Assay, B-cell binding and cytotoxicity
Keywords: DXR; doxorubicin; mAb; monoclonal antibody; SL; non-targeted long-circulating (Stealth®) liposomes; SIL; long-circulating antibody-targeted liposomes (Stealth® immunoliposomes); αCD19; anti-CD19 mAb; αCD20; anti-CD20 mAb (Rituxan); HSPC; hydrogenated
Enumeration and detection of aerosolized Aspergillus fumigatus and Penicillium chrysogenum conidia and hyphae using a novel double immunostaining technique
Keywords: HIA; halogen immunoassay; IgE; immunoglobulin E; mAb; monoclonal antibody; SPT; skin prick test; MCE; mixed cellulose ester; BSA; bovine serum albumin; PBS; phosphate-buffered saline; HRP; horseradish peroxidase; Allergen; Conidia; Fungi; Germination; Imm
The role of tissue factor and P-selectin in the procoagulant response that occurs in the first month after on-pump and off-pump coronary artery bypass grafting
Keywords: ADP; adenosine diphosphate; ANOVA; analysis of variance; CABG; on-pump coronary artery bypass grafting; FITC; fluorescein isothiocyanate; GLM; general linear model; mAb; monoclonal antibody; MFI; mean fluorescence intensity; OPCAB; off-pump coronary arter
Cell-binding properties of the envelope proteins of porcine endogenous retroviruses
Keywords: Porcine endogenous retroviruses; Receptors; Xenotransplantation; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; FeLV; feline leukemia virus; GaLV; gibbon ape leukemia virus; HEK; human embryonic kidney; MAb; monoclonal antibody; MLV; mur
Identification and expression of a new type II transmembrane protein in human mast cells
Keywords: MCEMP1; mast cell-expressed membrane protein 1; CBMC; cord blood-derived mast cell; mAb; monoclonal antibody; RT-PCR; reverse transcriptase-polymerase chain reaction; Mast cell; Transmembrane protein; Expression; Lung, Cellular marker;
Inhibition of brain damage by edaravone, a free radical scavenger, can be monitored by plasma biomarkers that detect oxidative and astrocyte damage in patients with acute cerebral infarction
Keywords: OxLDL; oxidized low-density lipoprotein; NIHSS; NIH Stroke Scale; mAb; monoclonal antibody; SOD; superoxide dismutase; DWI; diffusion-weighted imaging; PWI; perfusion-weighted imaging; FLAIR; flow-sensitive alternating inversion recovery; IR; inversion-re
Protein-protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
Keywords: 2-D electrophoresis; two-dimension electrophoresis; cDNA; DNA complementary to RNA; Ig; immunoglobulin(s); kDa; kilodalton(s); mAb; monoclonal Ab; ONPG; o-nitrophenyl β-d-galactopyranoside; ORF; open reading frame; PAGE; polyacrylamide gel electrophoresi
Biological activity of recombinant chicken interleukin-6 in chicken hybridoma cells
Keywords: FBS; fetal bovine serum; GST; glutathione S-transferase; IL-6; interleukin-6; IMDM; Iscove's modified Dulbecco's medium; Ig; Immunoglobulin; Jak; Janus kinase; mAb; monoclonal antibody; PrP; prion protein; rchIL-6; recombinant chicken IL-6; SDS-PAGE; sodi
Binding affinity and capacity of putative adaptor-mediated sorting of a Type I membrane protein in Leishmania mexicana
Keywords: AP; adaptor; GPI; glycosylphosphatidylinositol; mAb; monoclonal antibody; MBAP; membrane bound acid phosphatase; MVT; multivesicular tubule; PM; plasma membrane; Type I membrane protein; Membrane protein sorting; Membrane flow; Adaptor complex; Leishmania
Development of an assay for the quantification of type I collagen synthesis in the guinea pig
Keywords: PICP; procollagen type I C-terminal propeptide; SPR; Surface plasmon resonance; ELISA; enzyme-linked immunosorbent assay; mAb; monoclonal antibody; GPSX; guinea pig skin extract; RU; response units; SDS; sodium dodecyl sulphate; CV; column volumes; mIgG;
Retinoic acid blocks pro-inflammatory cytokine-induced matrix metalloproteinase production by down-regulating JNK-AP-1 signaling in human chondrocytes
Keywords: AP-1; activator protein-1; EMSA; electrophoresis mobility shift assay; ERK; extracellular signal-regulated protein kinase; 4-HPR; N-(4-hydroxyphenyl)retinamide; IκBα; I kappa B alpha; IL; interleukin; JNK; c-jun N-terminal kinase; mAb; monoclonal antibo
CD39-associated high ATPase activity contribute to the loss of P2X7-mediated calcium response in LCL cells
Keywords: ALL; acute lymphoblastic leukemia; AML; acute myelogenous leukemia; ATP; adenosine-5â²-triphosphate; BSA; bovine serum albumin; βγMeATP; β,γ-methylene ATP; BzATP; 2â²,3â²-O-(4-benzoylbenzoyl)-ATP; CML; chronic myelogenous leukemia; DEPC; diethylpyr
Engineering dihydropteroate synthase (DHPS) for efficient expression on M13 phage
Keywords: DHPS; Dihydropteroate synthetase; Mab; Monoclonal antibody; WT; Wild type; Dihydropteroate synthase; Phage display; Protein expression; Protein engineering; Cysteine residue;
Flow cytometric assessment of Leishmania spp metacyclic differentiation: Validation by morphological features and specific markers
Keywords: Trypanosomatid parasitic protozoa; Metacyclic promastigotes; Metacyclogenesis; LPG; lipophosphoglycan; PNA; peanut agglutinin; BPL; Bauhinia purpurea lectin; FCM; flow cytometry; FSC; forward-angle light scatter; SSC; side-angle light scatter; mAb; monocl
Microdermabrasion: A molecular analysis following a single treatment
Keywords: AP; activator protein; ATF; activating transcription factor; ERK; extracellular signal-regulated kinase; HMG CoA; 3-hydroxy-3-methylglutaryl coenzyme A; IL; interleukin; JNK; C-jun NH terminal kinase; MAB; monoclonal antibody; MAP; mitogen activated prote
Inorganic arsenite alters macrophage generation from human peripheral blood monocytes
Keywords: APL; acute promyelocytic leukemia; As-Mp; arsenite-induced macrophages from peripheral blood monocytes; BHT; 2,6-di-tert-butyl-4-methylphenol; CSF; colony stimulating factor; DCFH-DA; 2â²7â²-dichlorofluorescein diacetate; DMPO; 5,5-Dimethyl-1-pyrroline
Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration
Keywords: Aggrecanase; Matrix metalloproteinases; Cartilage catabolism; MMP; matrix metalloproteinase; IL-1; interleukin-1; OSM; oncostatin M; GAG; glycosaminoglycan; IGD; interglobular domain of the aggrecan core protein; DMMB; dimethylmethylene blue; MAb; monoclo
1α,25-Dihydroxyvitamin D3 restores thymocyte apoptosis sensitivity in non-obese diabetic (NOD) mice through dendritic cells
Keywords: Type 1 diabetes; Apoptosis; NOD mice; Thymus; Vitamin D; NOD; non-obese diabetic; NOR; non-obese diabetes-resistant; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; DC; dendritic cell; APC; antigen-presenting cell; mAb; monoclonal antibody; TUNEL; terminal deo
Investigation of active form of catalytic antibody light chain 41S-2-L
Keywords: mAb; monoclonal antibody; PB; phosphate buffer; PBS; phosphate-buffered saline; KLH; keyhole limpet haemocyanine; env gp41; envelope glycoprotein of HIV-1gp41; BSA; bovine serum albumin; Catalytic antibody; Serine protease; Catalytic triad; Fluorescence;
Identification of HLA-A*0111N: A Synonymous Substitution, Introducing an Alternative Splice Site in Exon 3, Silenced the Expression of an HLA-A Allele
Keywords: HLA-A*0111N; null allele; SBT; alternative splicing; EBV; Epstein-Barr virus; FCM; flow-cytometric; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HLA; human leukocyte antigen; 1D-IEF; one-dimensional isoelectric focusing; mAb; monoclonal antibody; MUD;
Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite
Keywords: DARC; Duffy antigen receptor for chemokines; EDTA; ethylenediaminetetraacetic acid; GPA; glycophorin A; mAb; monoclonal antibody; PBS; phosphate buffered saline; Erythrocyte; GPI anchor; Invasion; Malaria; Plasmodium yoelii;
Antisense-Mediated Suppression of Heparanase Gene Inhibits Melanoma Cell Invasion
Keywords: Malignant melanoma; heparanase; heparan sulfate; invasion and metastasis; anti-sense gene delivery; BCA; bicinchoninic acid; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; EDTA; ethylenediaminetetraacetic a
Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors
Keywords: HCV; hepatitis C virus; NS; nonstructural protein; MAPK/ERK; mitogen-activated protein kinase/extracellular signal-regulated kinase; LDLR; low density lipoprotein receptor; mAb; monoclonal antibody; MTT; dimethyl thiozolyl-2â², 5â²-diphenylo-2-H-tetrazo
Human neuroblastoma GOTO cells express CD44 and localize it into lipid rafts upon differentiation into Schwannian cells
Keywords: Monoclonal antibody; Bromodeoxyuridine; Serum depletion; Sphingolipids; Alternative splicing; BrdU; 5-bromo-2â²-deoxyuridine; CD44H; CD44 of hemopoietic form; mAb; monoclonal antibody; FACS; fluorescence-activated cell sorter; FITC; fluorescein isothiocy
Probing leukocyte traffic in lymph from oro-nasal mucosae by cervical catheterization in a sheep model
Keywords: DC; Dendritic cells; PA; Pseudo-afferent; mAb; Monoclonal antibody; S.D.; Standard deviation; Cell traffic; Lymph; Sheep; Oro-nasal mucosae;
The apolipoprotein(a) component of lipoprotein(a) mediates binding to laminin: contribution to selective retention of lipoprotein(a) in atherosclerotic lesions
Keywords: Lp(a); lipoprotein(a); LDL; low density lipoprotein; apo(a); apolipoprotein(a); apoB-100; apolipoprotein B-100; ECM; extracellular matrix components; KIV; kringle IV; KV; kringle V; LBS; lysine binding site(s); mAb; monoclonal antibody; ε-ACA; ε-aminoca
Monoclonal antibody-based competitive assay for the sensitive detection of coeliac disease toxic prolamins
Keywords: ELISA; enzyme-linked immunosorbent assay; CD; coeliac disease; PWG; Prolamin Working Group; ALP; alkaline phosphatase; pNPP; p-nitrophenyl phosphate; HRP; horse radish peroxidase; TMB; tetramethyl benzidine; SATA; N-succinimidyl-S-acetylthioacetate; PBS;
Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats
Keywords: head injury; myelin inhibitors; tract-tracing; cognition; hippocampus; ANOVA; analysis of variance; BDA; biotinylated dextran amine; CNS; central nervous system; CST; corticospinal tract; DAB; 3,3-diaminobenzidine; FP; fluid percussion; GAP; growth-associ
Antenatal glucocorticoids blunt the functioning of the hypothalamic-pituitary-adrenal axis of neonates and disturb some behaviors in juveniles
Keywords: pregnancy; CRH expression; AVP expression; behavioral tests; development; ACTH; adrenocorticotrophin; AVP; arginine vasopressin; BW; body weight; CRH; corticotropin releasing hormone; DEX; dexamethasone; GD; gestational day; GR; glucorticoid receptor; HPA
Enveloped particles in the serum of chronic hepatitis C patients
Keywords: HCV; hepatitis C virus; ORF; open reading frame; NC; non-coding; C; core; E1; envelope 1; E2; envelope 2; HVR1; hyper variable region; HCV-sp; HCV-serum particles; EDTA; ethylene diamine tetraacetic acid; mAb; monoclonal antibody; SDS; sodium dodecyl sulp
Desensitization of mast cells' secretory response to an immuno-receptor stimulus
Keywords: ATCC; american type culture colection; BSA; bovine serum albumine; DCCM; defined cell culture medium; DMEM; dulbecco's mod eagle medium; DMSO; dimethyl sulphoxide; DNP; dinitro phenyl; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked immunosorb
Natural Variation in Toxicity of Wheat: Potential for Selection of Nontoxic Varieties for Celiac Disease Patients
Keywords: CD; celiac disease; HMW; high molecular weight; IFN-γ; interferon-γ; LMW; low molecular weight; mAb; monoclonal antibody;
Conformational changes in the antibody constant domains upon hapten-binding
Keywords: Ab; antibody; mAb; monoclonal antibody; Ag; antigen; BCR; B cell receptor; BSA; bovine serum albumin; ITC; isothermal titration calorimetry; NP; (4-hydroxy-3-nitrophenyl)acetyl; NP-Cap; É-NP-aminocaproic acid; PBS; phosphate buffered saline; SpA; staphyl
PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites
Keywords: DV; digestive vacuole; IEM; immunoelectron microscopy; MAb; monoclonal antibody; PfALD; Plasmodium falciparum aldolase; PfCRT; Plasmodium falciparum chloroquine resistance transporter; PfEXP-1 or -2; Plasmodium falciparum exported protein 1 or 2; PfSERP;
Immunotherapy for the treatment of drug abuse
Keywords: Clinical trials; Vaccine; Drug dependence; Cocaine; Methamphetamine; Nicotine; mAb; monoclonal antibody; PCP; phencyclidine; RSV; respiratory syncytial virus;
Characterisation of lesional infiltrates of dendritic cells and T cell subtypes during primary infestation of sheep with Psoroptes ovis, the sheep scab mite
Keywords: CI; confidence interval; DAB; 3,3â²-diaminobenzidine; mAb; monoclonal antibody; RT; room temperature; TBS; Tris buffered saline; ZSF; zinc salts fixative; Sheep; Psoroptes ovis; Immunhistochemistry; Dendritic cells; T cells; Lymphocyte subpopulations;
Complexes between C1q and C3 or C4: Novel and specific markers for classical complement pathway activation
Keywords: AHG; aggregated human IgG; AU; arbitrary units; C3b/c; C3b/bi/c; C4b/c; C4b/bi/c; CPB; cardiopulmonary bypass; CRP; C-reactive protein; EDTA; ethylene diamine tetraacetic acid; kDa; kilodalton; mAb; monoclonal antibody; MASP; MBL-associated serine proteas
E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor
Keywords: Abi-1; Abl-interactor-1; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; GAP; GTPase-activating protein; GEFs; guanine nucleotide exchange factors; GST; glutathione-S-transferase; mAb; monoclonal antibody; pAb; polyclonal antibody; P
Evaluation of two anti-gp91phox antibodies as immunoprobes for Nox family proteins: mAb 54.1 recognizes recombinant full-length Nox2, Nox3 and the C-terminal domains of Nox1-4 and cross-reacts with GRP 58
Keywords: 2-DE; two dimensional electrophoresis; ASB-14; amidosulfobetaine-14; ATP; adenosine 5â²-triphosphate; BCIP/NBT; 5-bromo-4-chloro-3-indolyl phosphate/nitro blue tetrazolium; CHAPS; (3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; CGD; chronic g
Kinetics of charge translocation in the passive downhill uptake mode of the Na+/H+ antiporter NhaA of Escherichia coli
Keywords: DDM; dodecyl-β-d-maltoside; mAb; monoclonal antibody; SSM; solid supported membrane; His-NhaA; His-tagged NhaA Na+/H+ exchanger; IC50; half maximum inhibitory concentration; RSO; right side out; CholineCl; C5H14NOCl; LPR; lipid to protein ratio; NhaA; So
Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS
Keywords: APC; adenomatous polyposis coli; CKI; casein kinase I; GSK-3β; glycogen synthase kinase-3β; ICAT; inhibitor of β-catenin; Mab; monoclonal antibody; LiCl; lithium chloride; IF; immunofluorescence; MT; microtubule; AGS cells; Wnt signaling; Giant cell fo