Keywords: MPP +; Estrogen-related receptor α; APP/PS1 mice; Amyloidogenesis; Tau phosphorylation; Aβ; amyloid protein; AD; Alzheimer's disease; ADAM10; a disintegrin and metalloproteinase 10; AMPK; AMP-activated protein kinase; APP; β-amyloid precursor protein; APP/PS1
مقالات ISI MPP + (ترجمه نشده)
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Keywords: MPP +; 6-OHDA; 6-hydroxydopamine; L-DOPA; L-3,4-dihydroxyphenylalanine; MB; methylene blue; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; OD; optical density; p; probenecid; PD; Parkinson's disease; SNpc; substantia nig
Keywords: MPP +; AD; Alzheimer's disease; DA; dopamine; DAergic; dopaminergic; hMAO-A; human monoamine oxidase A; hMAO-B; human monoamine oxidase B; HRP; horseradish peroxidase; IC50; the half maximal inhibitory concentration; i.p.; intraperitoneal; Ki; inhibition const
Keywords: MPP +; AcH; acetaldehyde; CTIQs; catechol isoquinolines; DA; dopamine; DMDHIQ+; 1,2-dimethyl-6,7-dihydroxyisoquinolinium ion; ISOP; isoproterenol; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-Methyl-4-phenylpyridinium; N-Me-Sal; N-methyl-salsolino
Keywords: MPP +; OS; oxidative stress; ROS; reactive oxygen species; MG; methylglyoxal; glo 1; glyoxalase-1; glo 2; glyoxalase-2; AGEs; advanced glycation end products; ASD; autism spectrum disorder; GSH; reduced glutathione; cas-3; caspase-3; NeuN; neuronal specific nucl
Keywords: MPP +; Parkinson's disease; Substantia nigra; Mitochondria; MPP+; Dopamine; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; COX5β; cytochrome c oxidase subunit 5β; DDSA; dodecenylsuccinic anhydride; DMEM; high glucose Dulbecco's modified Eagle's medium; DMP; d
Keywords: MPP +; PC12 cells; Rat adrenal pheochromocytoma cells; SNCA; α-synuclein; pDNA; plasmid DNA; BBB; blood-brain barrier; GNP; gold nanoparticles; CTS; chitosan; DTPA; 3,3â²-dithiodipropionic acid; NHS; N-hydroxysuccinimide; DTSP; dithiobis-(succinimidyl propio
Keywords: MPP +; 3-HK; 3-hydroxykynurenine; 6-OHDA; 6-hydroxydopamine; A; Amygdala; ACMSD; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; AD; Alzheimer's disease; AD; Anterodorsal nucleus (Thalamus); α-syn; Alpha-synuclein; CCL2; Chemokine (CC motif) ligand 2;
Keywords: MPP +; DNP; 2/4-dinitrophenol; MPTP; 1-methyl-4-phenyl-1/2/3/6-tetrahydro-pyridine; PD; Parkinson's disease; MPP+; 1-methyl-4-phenylpyridine; TH; tyrosine hydroxylase; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium binding adaptor molecule-1; 1-
Keywords: MPP +; organic cation transporters (OCTs); renal clearance; hepatic transport; hepatocytes; elderly; AUC; area under the curve; CKD; chronic kidney disease; CVD; cardiovascular disease; FMO3; flavin-containing monooxigenase 3; HEK; human embryonic kidney; HK; h
Keywords: MPP +; Polyphenols; Antibiotics; Antioxidants; PACAP; Aβ; β-amyloid; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; CAT; catalase; CNS; central nervous system; COX-2; cyclooxyge
Keywords: MPP +; pulmonary; tissue partition; pharmacokinetics; pulmonary drug delivery; distribution; Cu,cell; intracellular unbound drug concentration; Cu,lungISF; unbound drug concentration in the lung interstitial fluid; fu,lung; fraction of unbound drug in diluted lu
Keywords: MPP +; DA; dopaminergic; MPP+; 1-methyl-4-phenylpyridinium; PD; Parkinson's disease; TH; tyrosine hydroxylase; Drosophila; Mitochondria; drp1; opa1; Parkinson;
Keywords: MPP +; 3-NPA; 3-nitropropionic acid; 6-OHDA; 6-hydroxy dopamine; AD; Alzheimer's disease; AIF; apoptosis inducing factor; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; AÃ; β-amyloid peptide; CA; trans-cinnamaldehyde; Cat; catalase; CBP;
Keywords: MPP +; 6-OHDA; 6-hydroxydopamine; ADTIQ; 1-acetyl-6, 7-dihydroxyl-1, 2, 3, 4-tetrahydroisoquinoline; AMPK; 5â²-AMP-activated protein kinase; ATF; activating transcription factor 6; ATM; ataxia telangiectasia mutated; CHOP; CCAAT/-enhancer-binding protein homolo
Keywords: MPP +; OS; oxidative stress; CNS; central nervous system; ROS; reactive oxygen species; SOD; superoxide dismutase; CAT; catalase; Cu; copper; Zn; zinc; Mn; manganese; Fe; iron; Ni; nickel; DA; dopamine; PHOX; NADPH oxidase; Nrf2; nuclear factor erythroid 2-relat
Keywords: MPP +; ANOVA; analysis of variance; BBB; blood-brain barrier; GDNF; glia-derived neurotrophic factor; GLP-1; glucagon-like peptide 1; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; TH; tyrosine
Keywords: MPP +; Autophagic flux; Nigericin; MPP+; Bak; Neurodegeneration
Keywords: MPP +; SGZ; subgranular zone; DG; dentate gyrus; SVZ; subventricular zone; CNS; central nervous system; NPCs; neural precursor cells; ROS; reactive oxygen species; LPS; lipopolysaccharide; Dox; doxycycline; MPP+; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; RNS
Keywords: MPP +; PD; Parkinson's disease; MPP+; 1-methyl-4-phenylpyridinium ion; DAT; dopamine transporter; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SNpc; substantia nigra pars compacta; DOPAC; 3,4-dihydroxyphenylacetate; HVA; homovanillic acid; ODEs; ordinary
Keywords: MPP +; Valproic acid; MPP+; Neural stem cells; Cell death; Cell survival; Epilepsy;
Keywords: MPP +; AC; adenylate cyclase; AD; Alzheimer's disease; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; AOAA; aminooxyacetate; cAMP; cyclic adenosine monophosphate; CBS; cystathionine β-synthase; CNS; central nervous system; CSE; cystathionine
Keywords: MPP +; PD; Parkinson's disease; ASYN; alpha-synuclein; CT cybrids; (control cybrids); sPD cybrids; (sporadic Parkinson's disease cybrids); mtDNA; mitochondrial DNA; MPP+; 1-methyl-4-phenylpyridinium; NAP; Mitochondria dynamics; Microtubule network;
Keywords: MPP +; PAs; pyrrolizidine alkaloids; MCT; monocrotaline; OCT1; organic cation transporter 1; MDCK; Madin-Darby canine kidney; MPP+; 1-methyl-4-phenylpyridinium; d-THP; d-tetrahydropalmatine; DHM; dehydromonocrotaline; CYP; cytochrome P450; ASP+; 4-(4-(dimethyl
Keywords: MPP +; ABC; ATP-binding cassette; ANPs; acyclic nucleoside phosphonates; BCRP/ABCG2; breast cancer resistance protein; CNTs; concentrative nucleoside transporters; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; hCNT2; human con
Keywords: MPP +; APC; apparent partition coefficient; BCRP; breast cancer resistance protein; CH; cholate; cLPM; canalicular liver plasma membrane; DC; deoxycholate; GC; glycocholate; GDC; glycodeoxycholate; HNAP; hydroxy-2-naphthoic acid; Mw; molecular weight; MATE; mult
Keywords: MPP +; SNc; substantia nigra pars compacta; PD; Parkinson disease; NMS; nonmotor symptoms; MAO-B; monoamine oxidase-B; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxy dopamine; GBA; glucocerebrosidase; STN
Keywords: MPP +; ABC; ATP-binding cassette transporter; ASK1; apoptosis signal-regulating kinase 1; BBB; blood-brain barrier; BSO; l-buthionine-(S,R)-sulfoximine; COMT; catechol-O-methyltransferase; DA; dopamine; DAT; dopamine transporter; DHBT-1; 7-(2-aminoethyl)-3,4-d
Keywords: MPP +; PD; Parkinson's disease; AD; Alzheimer's disease; HD; Huntington's Disease; ALS; Amyotrophic Lateral Sclerosis; TAR DNA; binding protein TDP-43; TCA; tricarboxylic acid cycle; ROS; reactive oxygen species; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrod
Blood-brain barrier permeability and neuroprotective effects of three main alkaloids from the fruits of Euodia rutaecarpa with MDCK-pHaMDR cell monolayer and PC12 cell line
Keywords: MPP +; EF; Euodiae Fructus; EDM; evodiamine; RCP; rutaecarpine; DEDM; dehydroevodiamine; Papp; apparent permeability coefficients; P-gp; P-glycoprotein; MPP+; 1-methyl-4-phenylpyridinium ion; H2O2; hydrogen peroxide; TCM; traditional Chinese medicine; BBB; blood
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway
Keywords: MPP +; Aβ; β-amyloid; CNS; central nervous system; CR3; complement receptor 3; DAMPs; damage associated molecular patterns; DEPs; diesel exhaust particles; DHE; dihydroethidium; Erk; extracellular regulated protein kinases; HMGB1; high-mobility group box 1; Ib
Inhibition of BDNF production by MPP+ through up-regulation of miR-210-3p contributes to dopaminergic neuron damage in MPTP model
Keywords: MPP +; BDNF; MPP+; miR-210-3p; Neuron damage; Parkinson's disease;
Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family
Keywords: MPP +; New psychoactive substances; Legal high; Phenmetrazine; Monoamine transporter; Amphetamine; 5-HT; 5-hydroxytryptamine; DA; dopamine; DAT; dopamine transporter; FPM; fluorophenmetrazine; HEK293Â cells; human embryonic kidney cells; KHB; Krebs-HEPES-buffer;
miR-494-3p modulates the progression of in vitro and in vivo Parkinson's disease models by targeting SIRT3
Keywords: MPP +; PD; Parkinson's disease; SOD; superoxide dismutase; LDH; lactate dehydrogenase; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; ROS; reactive oxygen species; SNpc; substantia nigra pars compacta; DA; dopaminergic; miRNAs; microRNAs; snRNA; sm
Simultaneous determination of six bioactive saponins from Rhizoma Panacis Japonici in rat plasma by UHPLC-MS/MS: Application to a pharmacokinetic study
Keywords: MPP +; RPJ; Rhizoma Panacis Japonici; tSRPJ; total saponins from Rhizoma Panacis Japonici; OA; oleanolic acid; PPD; 20(S)-protopanaxadiol; PPT; 20(S)-protopanaxatriol; CS; chikusetsusaponin; G; ginsenoside; He; hemsgiganoside; PK; pharmacokinetics; NF-κB; nucle
Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway
Keywords: MPP +; Agmatine; Akt; HT22; Ketamine; Neuroprotection; p70S6 kinase; PSD95; 4E-BPs; 4E binding proteins; ANOVA; analysis of variance; DMEM; Dulbecco's Modified Eagle Medium; ECT; electroconvulsive therapy; CUS; chronic unpredictable stress; FST; forced swim test
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: MPP +; Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease
Keywords: MPP +; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; BCL2; B-cell lymphoma 2; BDNF; brain-derived neurotrophic factor; DAVID; database annotation, visualization, and integrated discovery; DCF; 2â²,7â²-dichlorofluorescin; GAPDH; glyceraldehyde 3-
The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition
Keywords: MPP +; 4-PP; 4-phenylpyridine; DMSO; dimethylsulphoxide; DV; dependent variable; hNNMT; recombinant human NNMT; IV; independent variable; kcat/Km; catalytic efficiency; MeNH; 2N-methylnorharman; MMP; mitochondrial membrane potential; MPP+; 1-methyl-4-phenylpyrid
Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel
Keywords: MPP +; OCT1; Organic Cation Transporter 1; hOCT1; human OCT1; HEK; Human Embryonic Kidney; EV; empty vector; MPP+; 1-methyl-4-phenylpyridinium; TEA; tetraethylammonium; CCF; competitive counter flow; TMD; transmembrane domains; CHARMm; Chemistry at Harvard Macro
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease
Keywords: MPP +; Parkinson's disease; Ginsenoside Rb1; Glutamatergic transmission; Glutamate transporters; EAAC1; excitatory amino acid carrier-1; EAATs; excitatory amino acid transporters; GLAST; glutamate/aspartate transporter; GLT-1; glutamate transporter-1; mEPSCs; mi
Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153
Keywords: MPP +; α-SYN; alpha-synuclein; ROS; reactive oxygen species; 3â²-UTR; 3â²-untranslated region; DAT; dopamine transporter; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; α-synuclein; microRNA; 3â²-UTR; Mitochondria; Pa
MPP+ inhibits mGluR1/5-mediated long-term depression in mouse hippocampus by calpain activation
Keywords: MPP +; MPP+; Calpain; DHPG; Hippocampus; Long-term depression;
Signaling by growth/differentiation factor 5 through the bone morphogenetic protein receptor type IB protects neurons against kainic acid-induced neurodegeneration
Keywords: MPP +; MPP+; 1-methyl-4-pyridinium; 6-OHDA; 6-hydroxydopamine; BMPRII; bone morphogenetic protein type II receptor; BMPRIB; bone morphogenetic protein type IB receptor; BMPRIB-CA; constitutively active BMPRIB; GAPDH; glyceraldehyde phosphate dehydrogenase; GDF-5
SIRT3 deacetylated and increased citrate synthase activity in PD model
Keywords: MPP +; Parkinson disease; SIRT3; Deacetylation; Neuroprotection; Enzyme activity; Mitochondria; PD; Parkinson's disease; DA; dopaminergic; ATP; adenosine triphosphate; CS; citrate synthase; IDH2; isocitrate dehydrogenase 2; TCA; citric acid cycle; PDH; pyruvated
Redox signaling in acute oxygen sensing
Keywords: MPP +; AM; adrenal medulla; CB; carotid body; ETC; electron transport chain; H2O2; hydrogen peroxide; MCI; mitochondrial complex I; MCII; mitochondrial complex II; MCIII; mitochondrial complex III; MCIV; Mitochondrial complex IV; MPP+; 1-methyl-4-phenylpyridiniu
Neuroprotective effects of total flavonoid fraction of the Epimedium koreanum Nakai extract on dopaminergic neurons: In vivo and in vitro
Keywords: MPP +; DA; dopamine; ERE; estrogen response element; MES23.5; dopaminergic hybridoma cell line; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantial nigra; SNpc; substantia nigra pars
β-Estradiol-3-benzoate confers neuroprotection in Parkinson MPP+ rat model through inhibition of lipid peroxidation
Keywords: MPP +; MPP+; β-Estradiol-3-benzoate; Parkinson's disease; Antioxidants; PON2;
Interspecies comparison of the functional characteristics of plasma membrane monoamine transporter (PMAT) between human, rat and mouse
Keywords: MPP +; DA; dopamine; DAT; dopamine transporter; ENT; equilibrative nucleoside transporters; EPI; epinephrine; 5-HT; serotonin; MDCK; Madin-Darby canine kidney; MPP+; 1-methyl-4-phenylpyridinium; NE; norepinephrine; NBMPR; S-(4-nitrobenzyl)-6-thioinosine; NET; th
Phenolic amides with anti-Parkinson's disease (PD) effects from Nicandra physaloides
Keywords: MPP +; Nicandra physaloides; Phenolic amides; MPP+; SH-SY5Y; PD;