دانلود مقالات ISI درباره Mtorc2 + ترجمه فارسی

Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014

Keywords: 3-MA; 3-methyaldenine; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; mTOR; mammalian target or rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; S6K; p70-S6 Kinase 1; LC3B; light chain 3B; Colorectal cancer; AZD-2014; mTOR complexes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Phenotypes associated with inherited and developmental somatic mutations in genes encoding mTOR pathway components

Keywords: mTOR; Mamalian target of rapamycin; PI3K; phosphoinositide 3-kinase related kinase; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; AMP; Adenosine monophosphate; ATP; Adenosine triphosphate; S6K; ribosomal S6 Kinase; 4E-BP1; eukaryotic initiation factor 4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways

Keywords: EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; mTOR; mammalian target of rapamycin; mTORC2; mTOR complex 2; RMAECs; rat mesenteric arterial endothelial cells; rTERT; rat telomerase reverse transcriptase; SA-β-gal; senescence-as

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Keywords: Akt1; v-akt murine thymoma viral oncogene homolog 1; AMBRA; Autophagy/Beclin-1 regulator 1; AMPK; AMP-dependent protein kinase; ATG; autophagy-related; BECN1; beclin 1; DEPTOR; DEP domain containing mTOR-interacting protein; EGFR; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

mTORC2 in the center of cancer metabolic reprogramming

Keywords: mTORC2; c-Myc; metabolic reprogramming; epigenetics; drug resistance; glioblastoma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production

Keywords: ABCG1; ATP binding cassette transporter G1; BP-C; Bodipy-cholesterol; BP-CE; Bodipy-cholesteryl oleate; CETP; cholesteryl ester transfer protein; DAF-2 DA; 4,5-diaminofluorescein diacetate; DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Influence of mTOR in energy and metabolic homeostasis

Keywords: mTORC1; mTORC2; Hypothalamus; Energy balance; Leptin; Hormone

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

Keywords: Skeletal muscle; Metabolism; Glucose uptake; mTORC2; Rictor; Glycolysis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Growing knowledge of the mTOR signaling network

Keywords: mTOR; mTORC1; mTORC2; Insulin; Amino acids; Energy;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis

Keywords: Rictor; mTORC2; CNS insulin; POMC neurons; AgRP neurons; Energy balance; Food intake; Obesity

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR signaling in tumorigenesis

Keywords: mTOR; the mechanistic target of rapamycin or the mammalian target of rapamycin; PIKK; phosphoinositide 3-kinase related protein kinase; ATM; ataxia-telangiectasia mutated; ATR; ataxia-telangiectasia and rad3-related; DNAPK; DNA-dependent protein kinase; R

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

Keywords: ATF-4; activating transcription factor 4; CB1; cannabinoid type-1 receptor; CB2; cannabinoid type-2 receptor; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; MEF; mouse embryonic fibroblast; mTORC1; mammalian target of rapamycin complex 1; mTOR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

β-Arrestin signal complex plays a critical role in adipose differentiation

Keywords: GHSR1a; growth hormone secretagogue receptor type 1a; PPARγ; peroxisome proliferator-activated receptor; C/EBPα; CCAAT/enhancer-binding protein α; C/EBPβ; CCAAT/enhancer-binding protein β; C/EBPδ; CCAAT/enhancer-binding protein δ; PI3K; phosphatidy

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2013 سفارش ترجمه

Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress

Keywords: Protor-2; Tristetraprolin; mTORC2; mRNA stability; Stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling

Keywords: mTORC1; mTORC2; endoplasmic reticulum stress; unfolded protein response; anabolism; apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Keywords: BCA; bicinchoninic acid protein; ECL; enhanced chemiluminescence; IR; insulin receptor; mTOR; mammalian target of rapamycin; mTORC1; mammalian target of rapamycin complex 1; mTORC2; mammalian target of rapamycin complex 2; NODAT; new onset diabetes after

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin

Keywords: Cortical development; mTOR; mTORC1; mTORC2; Neural progenitor cell; Radial glia;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Estrogen receptor potentiates mTORC2 signaling in breast cancer cells by upregulating superoxide anions

Keywords: ER; estrogen receptor; ROS; reactive oxygen species; O2•−; superoxide anion; mTORC2; mammalian target of rapamycin complex 2; NAC; N-acetyl-l-cysteine; MnTBAP; Mn(III) tetrakis-(4-benzoic acid) porphyrin; E2; 17-β-estradiol; DHE; dihydroethidium; FBS

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor

Keywords: EGCG; (−)-epigallocatechin-3-gallate; PI3K; phosphoinositide-3-kinase; mTOR; mammalian target of rapamycin; PI(3,4,5)P3; phosphatidylinositol-3,4,5-triphosphate; ATP; adenosine 5′-triphosphate; mTORC2; mammalian target of rapamycin complex 2; FRAP1; F

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells

Keywords: PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex1; mTORC2; mTOR complex2; S6K1; p70 S6 kinase1; S6; ribosomal protein S6; 4E-BP1; eIF4E1 binding protein1; eIF2α; eukaryotic initiation factor 2α; PKR; ds RNA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Imidazo[1,5-a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2

Keywords: mTOR; mTORC1; mTORC2; Imidazo[1,5-a]pyrazine; Oral inhibitor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity

Keywords: cAMP; mTORC1; mTORC2; TSC2; PKA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Keywords: 4E-BP1; 4E binding protein 1; 5′UTR; 5′ untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5′-AMP-activated protein kinase; AMPK α1−/−; AMPK α1 subunit knockout; AMPKα1−/−α2−/−; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Energy metabolism in adult neural stem cell fate

Keywords: ACC; adenylate cyclase complex; AICAR; aminoimidazole carboxamide ribonucleotide; AMPK; AMP-activated protein kinase; Aspm; abnormal spindle-like microcephaly-associated; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; bHLH;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2011 سفارش ترجمه

Developmentally spliced PKCβII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport

Keywords: PKCβII; GLUT4; Akt; mTORC2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Hsp70 associates with Rictor and is required for mTORC2 formation and activity

Keywords: Hsp70; Rictor; mTORC2; Kinase activity; Heat shock

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway

Keywords: MHC; HLA class I; ERK; mTORC2; siRNA; Endothelial cells; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Raptor-rictor axis in TGFβ-induced protein synthesis

Keywords: mTORC1; mTORC2; Tuberin; 4EBP-1; eIF4E; S6 kinase; Akt

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه