دانلود مقالات ISI درباره Nmd + ترجمه فارسی

The identification of a novel isoform of EphA4 and ITS expression in SOD1G93A mice

Keywords: ALS; amyotrophic lateral sclerosis; BCA; bicinchoninic acid; CHO; Chinese hamster ovary; DAPI; 4′,6-diamidino-2-phenylindole; EphA; ephrin type-A receptor; EphA4-FL; full-length EphA4; EphB; ephrin type-B receptor; ESTs; expressed sequence tag sequences

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The histone lysine methyltransferase Ezh2 is required for maintenance of the intestine integrity and for caudal fin regeneration in zebrafish

Keywords: bp; base pair; dpf; days post fertilization; dpa; days post amputation; ezh2; enhancer of zeste homolog 2 (polycomb repressive complex 2 subunit); hpf; hours post fertilization; gcga; glucagon a; ins; insulin; NMD; nonsense-mediated decay; nt; nucleotide;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Experimental assessment of novel PAX6 splicing mutations in two Chinese families with aniridia

Keywords: PAX6; paired box gene 6; bp; base pair(s); del; delete; ins; insert; WAGR; Wilms tumor, aniridia, genitourinary anomalies and mental retardation; PD; paired domain; HD; homeodomain; PST; proline/serine/threonine-rich; PCR; polymerase chain reaction; NCBI;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa

Keywords: DEJ; dermal-epidermal junction; EB; epidermolysis bullosa; NMD; nonsense mediated mRNA decay; PTC; premature termination codon; RDEB; recessive dystrophic epidermolysis bullosa;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

E-selectin and sICAM-1, biomarkers of endothelial function, predict recurrence of venous thromboembolism

Keywords: AUC; area under the curve; ADMA; asymmetric dimethylarginine; APE; acute pulmonary embolism; CTEPH; chronic thromboembolic pulmonary hypertension; CD62E; cluster of differentiation 62 E, E-selectin; CRP; C-reactive protein; DVT; deep vein thrombosis; ED;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Polycistronic trypanosome mRNAs are a target for the exosome

Keywords: Trypanosoma brucei; Exosome; NMD; Polycistronic mRNA; trans-splicing; Trypanosomes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

MiR-128 and miR-125 regulate expression of coagulation Factor IX gene with nonsense mutation by repressing nonsense-mediated mRNA decay

Keywords: MicroRNA; Hemophilia; Factor IX; Nonsense mutation; NMD

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Adenosine Receptor Activation in the “Trigger” Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s)

Keywords: adenosine; endothelium; ischemia; pre-conditioning; Ach; acetylcholine; ANOVA; analysis of variance; FMD; flow-mediated dilation; GTN; glyceryltrinitrate; IR; ischemia-reperfusion; LV; left ventricular; NMD; nitrate-mediated dilation; rIPC; remote ischemi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The prevalent deep intronic c. 639 + 919 G > A GLA mutation causes pseudoexon activation and Fabry disease by abolishing the binding of hnRNPA1 and hnRNP A2/B1 to a splicing silencer

Keywords: α-Gal A; α-galactosidase A enzyme; ESE; exonic splicing enhancer; ESS; exonic splicing silencer; FGB; fibrinogen β gene; GLA; α-galactosidase A gene; hnRNP A1, A2/B1, F, and H; heterogeneous ribonucleoprotein A1, A2/B1, F, and H; NMD; nonsense-mediate

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewFibrate therapy and flow-mediated dilation: A systematic review and meta-analysis of randomized placebo-controlled trials

Keywords: RCTs; Randomised placebo-controlled trials; FMD; Flow-mediated dilation; NMD; Nitrate mediated dilation; NO; nitric oxide; PPARs; Peroxisome proliferatorâ¿¿activated receptorshs-CRP high-sensitivity C-reactive protein; SD; standard deviation; WMD; weighte

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Validity of transcutaneous PCO2 in monitoring chronic hypoventilation treated with non-invasive ventilation

Keywords: ABG; Arterial blood gas; CRF; Chronic hypercapnic respiratory failure; NIV; Non-invasive ventilation; NMD; Neuro muscular diseases; OHS; Obesity hypoventilation syndrome; PaCO2; Arterial CO2; PtcCO2; Transcutaneous PCO2; RTD; Restrictive thoracic disorder

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Targeted next generation sequencing of a panel of autism-related genes identifies an EHMT1 mutation in a Kleefstra syndrome patient with autism and normal intellectual performance

Keywords: ACMG; American College of Medical Genetics and Genomics; ADI-R; Autism Diagnostic Interview-Revised; ADOS; Autism Diagnostic Observation Schedule; ANK; ankyrin repeat; ASD; autism spectrum disorder; BDNF; brain derived neurotrophic factor; BWA; Burrows-Wh

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Insulin Signaling Augments eIF4E-Dependent Nonsense-Mediated mRNA Decay in Mammalian Cells

Keywords: PI3K/AKT/mTOR; Insulin; NMD; Translation; Processing body;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Bulbar impairment score predicts noninvasive volume-cycled ventilation failure during an acute lower respiratory tract infection in ALS

Keywords: AB; acute bronchitis; ALS; amyotrophic lateral sclerosis; ALSFRS-R; revised amyotrophic lateral sclerosis functional rating scale; APACHE II; Acute Physiology and Chronic Health Evaluation; ARF; acute respiratory failure; AUC; area under the curve; CAP; c

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Selenocysteine incorporation: A trump card in the game of mRNA decay

Keywords: Selenocysteine; NMD; mRNA decay;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of one novel CHD7 mutation in a patient from China with atypical CHARGE syndrome

Keywords: CHD; chromodomain helicase DNA-binding; PGM; personal genome machine; HGMD; Human Gene Mutation Database; PTC; premature termination codon; NMD; nonsense mediated decay; CHARGE syndrome; CHD7; Novel mutation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Late-onset spastic paraplegia: Aberrant SPG11 transcripts generated by a novel splice site donor mutation

Keywords: HSP; hereditary spastic paraplegia; SPG11; spastic paraplegia type 11; MRI; magnetic resonance imaging; NGS; next-generation sequencing; SSD; splice site donor; WES; whole exome sequencing; NMD; nonsense-mediated mRNA decay; Spastic paraplegia; SPG11; Who

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Phenotypic variability in a seven-generation Swedish family segregating autosomal dominant hearing impairment due to a novel EYA4 frameshift mutation

Keywords: ADNSHI; autosomal dominant nonsyndromic hearing impairment; HI; hearing impairment; HL; hearing loss; NMD; non-sense mediated mRNA decay; PTA; pure tone average; Autosomal dominant; Hearing impairment; Genome-wide linkage; DFNA10; EYA4; Mutation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Probenecid protects against cerebral ischemia/reperfusion injury by inhibiting lysosomal and inflammatory damage in rats

Keywords: 4-VO; four-vessel occlusion; CCAs; common carotid arteries; GFAP; glial fibrillary acidic protein; I/R; ischemia/reperfusion; Iba-1; ionized calcium-binding adaptor molecule-1; IOD; integrated optical density; ip; intraperitoneally; iv; intravenously; NMD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency

Keywords: DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Non-coding functions of alternative pre-mRNA splicing in development

Keywords: A3E; alternative 3′ terminal exon; APA; alternative cleavage and polyadenylation; ARE; AU-rich element; AS; alternative splicing; IR; intron retention; NMD; nonsense-mediated decay; NMTR; nonsense-mediated translational repression; NRE; nuclear retentio

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a novel MYOC mutation, p.(Trp373*), in a family with open angle glaucoma

Keywords: ANZRAG; Australian and New Zealand Registry of Advanced Glaucoma; BCVA; best corrected visual acuity; IOP; intraocular pressure; LE; left eye; mRNA; messenger RNA; MYOC; myocilin; NATA; National Association of Testing Authorities; NMD; nonsense mediated d

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Nonsense-mediated mRNA decay due to a CACNA1C splicing mutation in a patient with Brugada syndrome

Keywords: BrS; Brugada syndrome; cDNA; complementary DNA; ECG; electrocardiogram; HEK; human embryo kidney; hERG; human ether-à-go-go-related gene; ICa; calcium current; ICD; implantable cardioverter-defibrillator; mRNA; messenger RNA; NMD; nonsense-mediated mRN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Unusual splice site mutations disrupt FANCA exon 8 definition

Keywords: NMD; nonsense-mediated mRNA decay; PTC; premature termination codon; FA; Fanconi anemia; ExSpeU1; exon specific U1; U2AF; U2 auxiliary factor; HSF; human splicing finder; Nonsense codon; Fanconi anemia; Nonsense mediated mRNA decay; U1 small nuclear ribon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Defective pre-mRNA splicing in PKD1 due to presumed missense and synonymous mutations causing autosomal dominant polycystic disease

Keywords: ADPKD; autosomal dominant polycystic kidney disease; bp; base pairs; cDNA; DNA complementary to RNA; DMEM; Dulbecco's Modified Eagle's Medium; dNTP; deoxyribonucleoside triphosphate; ESE; exonic splicing enhancers; ESS; exonic splicing silencers; ISE; int

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

False start: Cotranslational protein ubiquitination and cytosolic protein quality control

Keywords: CHIP; C-terminus of Hsc70-interacting protein; DRiP; defective ribosomal product; ER; endoplasmic reticulum; ERAD; ER-associated protein degradation; NAC; nascent polypeptide-associated complex; NEF; nucleotide exchange factor; NGD; no-go decay; NMD; nons

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

First functional analysis of a novel splicing mutation in the B3GALTL gene by an ex vivo approach in Tunisian patients with typical Peters plus syndrome

Keywords: B3GALTL; beta-1,3-glucosyltransferase; cDNA; DNA complementary to RNA; PTC; premature translation stop codon; mRNA; messenger ribonucleic acid; NMD; nonsense-mediated mRNA decay; PPS; Peters plus syndrome; DNA; deoxyribonucleic acid; B3GTL; beta3-glycosyl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of a novel CCM2 gene mutation in an Italian family with multiple cerebral cavernous malformations and epilepsy: A causative mutation?

Keywords: CCM; cerebral cavernous malformation; KRIT1; K-Rev interaction trapped 1; PDCD10; Programmed Cell Death 10; NMD; Nonsense-mediated decay; MRI; Magnetic Resonance Imaging; MLPA; Multiplex ligation-dependent probe amplification; PCR; Polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Homozygous SALL1 Mutation Causes a Novel Multiple Congenital Anomaly-Mental Retardation Syndrome

Keywords: cDNA; Complementary DNA; CNS; central nervous system; CNS-TBS; Central nervous system-Townes-Brocks syndrome; mRNA; messenger RNA; MCA-MR; Multiple congenital anomaly-mental retardation; NMD; Nonsense-mediated mRNA decay; TBS; Townes-Brocks syndrome; TO

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A novel familial case of diffuse leukodystrophy related to NDUFV1 compound heterozygous mutations

Keywords: MD; mitochondrial respiratory chain disorders; CI; complex I; NMD; nonsense-mediated decay; Mitochondrial disease; Diffuse leukodystrophy; NDUFV1 mutations; Genetics;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Bis(12)-hupyridone, a novel acetylcholinesterase inhibitor, protects against glutamate-induced neuronal excitotoxicity via activating α7 nicotinic acetylcholine receptor/phosphoinositide 3-kinase/Akt cascade

Keywords: AChE; acetylcholinesterase; AD; Alzheimer's disease; B12H; bis(12)-hupyridone; CGNs; cerebellar granule neurons; DHβE; dihydro-β-erythroidine; GSK3β; glycogen synthase kinase 3β; mAChR; muscarinic acetylcholine receptor; MLA; methyllycaconitine; NMD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells

Keywords: miRNA; microRNA; DDX6; DEAD-box RNA helicase 6; NCR143/145; microRNA-143/145 host non-coding RNA gene; P-bodies; processing bodies; pri-miRNAs; primary microRNA transcripts; pre-miRNAs; microRNA precursors; DDX5; DEAD-box RNA helicase 5; DDX17; DEAD-box R

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability

Keywords: NMD; UPF1; SMG1; TEL2 phosphorylation; CK2; mRNP remodeling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of nonsense-mediated mRNA decay: Implications for physiology and disease

Keywords: NMD; microRNA; miR-128; Cancer; eIF2α; ATF4;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication

Keywords: HTLV-1; HTLV-1 Rex; NMD; Retroviral genomic RNA; Host-pathogen interaction;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA 125 represses nonsense-mediated mRNA decay by regulating SMG1 expression

Keywords: NMD; miRNA-125; SMG1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Analysis of aberrant splicing and nonsense-mediated decay of the stop codon mutations c.109G>T and c.504_505delCT in 7 patients with HMG-CoA lyase deficiency

Keywords: HMGCL; HMG-CoA lyase deficiency; NMD; NAS; Alternative splicing

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Signaling pathways that control mRNA turnover

Keywords: PTM; posttranslational modification; ARE; AU-rich elements; UTR; untranslated region; ARE-BP; ARE binding protein; IRE; Iron-responsive element; JRE; Jun-kinase response element; TTP; Tristetraprolin; KSRP; K-homology splicing regulator protein; RISC; RNA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA or NMD: Why Have Two RNA Silencing Systems?

Keywords: NMD; miRNA; Gene regulation; RNA degradation; Evolution

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Physiotherapy management in late-onset Pompe disease: Clinical practice in 88 patients

Keywords: ERT; enzyme replacement therapy; NMD; neuromuscular disorders; ADL; activities of daily living; MSE; muscle strengthening exercises; AET; aerobic exercise therapy; HEP; home exercise program; Pompe disease; Physical therapy management; Exercise therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Exploring Employment in Consultation Reports of Patients With Neuromuscular Diseases

Keywords: Employment; Muscular diseases; Occupations; Referral and consultation; Rehabilitation; Rehabilitation, vocational; Work; NMD; neuromuscular disease; OT; occupational therapy; PT; physical therapy; ST; speech therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Tomato paste supplementation improves endothelial dynamics and reduces plasma total oxidative status in healthy subjects

Keywords: ANOVA; analysis of variance; CVD; cardiovascular disease; FMD; flow-mediated dilatation; HDL; high-density lipoprotein; LDL; low-density lipoprotein; NMD; nitroglycerin-mediated dilatation; TOS; total oxidative status; Endothelial function; Lycopene; Caro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The upstream open reading frame of cyclin-dependent kinase inhibitor 1A mRNA negatively regulates translation of the downstream main open reading frame

Keywords: NMD; CDKN1A/p21/WAF1; uORF; CBP80; CBP20

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Altered N-methyl-d-aspartate receptor function in reelin heterozygous mice: Male–female differences and comparison with dopaminergic activity

Keywords: ANOVA, analysis of variance; CN, caudate nucleus; Het, heterozygous mice; ISI, inter-stimulus interval; IP, intra-peritoneal; NAc, nucleus accumbens core; NAsh, nucleus accumbens shell; NHMRC, National Health and Medical Research Council of Australia; NMD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

A new function of ROD1 in nonsense-mediated mRNA decay

Keywords: NMD; ROD1; UPF1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Research ReportCharacterization of the RNA-binding protein Musashi1 in zebrafish

Keywords: Msi1; Musashi1; Msi2; Musashi2; PNS; peripheral nervous system; SOP; sensory organ precursor; NS/PC; neural stem/progenitor cell; RRMs; RNA recognition motifs; CNS; central nervous system; KD; knock down; hpf; hours post-fertilization; NMD; nonsense-media

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Dramatically different levels of cacna1a gene expression between pre-weaning wild type and leaner mice

Keywords: CACNA1A; gene encoding P/Q type α1A subunit voltage-dependent calcium channel; CaV2.1; α1A subunit of P/Q voltage-dependent calcium channel; EA2; Episodic Ataxia type 2; tg; tottering; tg-la; leaner; rkr; rocker; rolling-nagoya; tg-rol; PTC; premature t

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2

Keywords: Ago2; MicroRNA; NMD; CBP80/20; eIF4E

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

FBN1 isoform expression varies in a tissue and development-specific fashion

Keywords: RT-PCR; real-time PCR; HEK; human embryonic kidney; NMD; nonsense mediated decay; Marfan syndrome; Fibrillin; Alternative splicing; Isoforms;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

A naturally-occurring carboxyl-terminally truncated α-scorpion toxin is a blocker of sodium channels

Keywords: 3′-UTR; 3′-untranslational region; CD; circular dichroism; DRG; dorsal root ganglia; IC50; 50% inhibitory concentration; VGPC; voltage-gated potassium channel; MALDI-TOF MS; matrix-assisted laser desorption ionization time-of-flight mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه