
Benzimidazole inhibitors of the protein kinase CHK2: Clarification of the binding mode by flexible side chain docking and protein-ligand crystallography
Keywords: ADP; adenosine diphosphate; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; CHK2; checkpoint kinase 2; GOLD; genetic optimisation for ligand docking; GST; glutathione S-transferase; KD; kinase domain; MOE; molecular operating environment;