Keywords: Mitophagy; Mitochondrial quality; High-content analysis; Nanosafety assessment; Superparamagnetic iron oxide nanoparticles; Graphene oxide-quantum dots; Au; gold; [Ca2+]i; intracellular Ca2+; CdTe; cadmium telluride; CeO2; cerium dioxide; DAPI; 4',6-dia
مقالات ISI (ترجمه نشده)
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Keywords: MAPT; PARK2; GBA; PINK1; LRRK2;
Keywords: Mitochondrial dysfunction; Testosterone; Mitophagy; Hypogonadism; BNIP3; BCL2/adenovirus E1B 19â¯kDa protein-interacting protein 3; TA; tibialis anterior; ERK 1/2; extracellular signal-regulated kinase 1/2; AMPK; 5â² AMP-activated protein kinase; LC3;
Keywords: MAP1LC3; microtubule-associated protein 1 light chain 3; LAMP1; lysosomes associated membrane protein 1; ROS; reactive oxygen species; EGCG; epigallocatechin gallate; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; VDAC1; voltage-dependent anion-selective
Keywords: Parkinson's disease; Rodent models; Rodent behaviour; Animal models; Alpha-synuclein; LRRK2; GBA; 6-OHDA; Rotenone; MPTP; FBXO7; ATP13A2; VPS35; Parkin; PINK1; DJ-1;
Keywords: α-Syn; α-synuclein; AD; Alzheimer's disease; BP; Biological Process; CAMS; Chinese Academy of Medical Sciences; CAPS; calcium-dependent activator of secretion; CC; Cellular component; CCK; Cell counting kit; DA; dopamine; DAVID; Database for annotation,
Keywords: ÎΨ; Mitochondrial membrane potential; Aβ; Amyloid beta; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionate; ApoE/D; Apolipoproteins E/D; BBB; Blood brain barrier; GSH; glutathione; HD; Huntington's disease; H2O2; hydrogen
Keywords: Parkinson's disease; Ghrelin; Dementia; AHN; adult hippocampal neurogenesis; AD; Alzheimer's Disease; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; AMP-activated protein kinase; AB; amyloid-β; ATG; autophagy-related; BBB; blood brain
Keywords: AMPK; 5â² adenosine monophosphate-activated protein kinase; AT; adipose tissue; BECN1; beclin 1; Bcl-2; B-cell lymphoma 2; Bim; Bcl-2-like protein 11 (BCL2L11); BMI; body mass index; CAD; coronary artery disease; CCS; Canadian Cardiovascular Society; CHO
Keywords: PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; DAMP; danger-associated molecular pattern; NLRP3; NOD-, LRR- and pyrin domain-containing 3; TLR; toll-like receptor; CLR; C-type lectin receptor; NLR; NOD-like receptor; RIG-I
Keywords: Hypoxia; ROS; IDH; DJ-1; PINK1; Metabolism;
Keywords: pink1; early-onset parkinsonism; Parkinson disease; parkinsonism; dystonia; movement disorders;
Keywords: CCCP; Carbonyl cyanide 3-chlorophenylhydrazone; COX IV; Cytochrome c oxidase subunit IV; DAPI; 4â²,6-Diamidino-2-phenylindole dihydrochloride; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl sulfoxide; Drp-1; Dynamin-related protein 1; DNPH; 2,4-d
Keywords: AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CHOP; C/EBP homologous protein; DRP1; dynamin-related protein 1; FIS1; fission protein 1; GRP78; 78Â kDa glucose-regulat
Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; SNpc; substantia nigra pars compacta; MnSOD; manganese superoxide dismutase; CuSOD; copper superoxide dismutase; NO; nitric oxide; O2â; superoxide anion; ONOOâ; peroxy
Keywords: Autosomal recessive Parkinson's disease; Mitochondria; Oxidative stress; Protein degradation; Parkin; PINK1;
Keywords: ABIN; A20 binding and inhibitor of NF-κB; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; Atg; autophagy-related gene; C9ORF72; chromosome 9 open reading frame 72; CC; coiled-coil; cIAP; cellular inhibitor of apoptosis protein; CYLD; cylin
Keywords: Polyphenols; Antibiotics; Antioxidants; PACAP; Aβ; β-amyloid; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; CAT; catalase; CNS; central nervous system; COX-2; cyclooxyge
Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: sEH; soluble epoxide hydrolase; mEH; microsomal epoxide hydroxylases; EETs; Epoxyeicosatrienoic acids; PD; Parkinson's disease; SNCA; synuclein alpha; LRRK2; leucine-rich repeat kinase 2; PARK2; E3 ubiquitin-protein ligase parkin; PINK1; PTEN induced pu
Keywords: Dopamine; Ferroptosis; Receptor; Iron; Lipid peroxidation; CCK-8; Cell Counting Kit-8; DRD; dopamine receptor; GPX4; glutathione peroxidase 4; GSH; glutathione; HMGB1; high mobility group box 1; LDH; lactate dehydrogenase; MDA; malondialdehyde; NRF2; nucl
Keywords: PD; Parkinson's disease; SNpc; substantia nigra pars compacta; LB; Lewy bodies; αSyn; αSynuclein; ER; endoplasmic reticulum; ERAD; ER-Associated Degradation; PINK1; PTEN-induced putative kinase 1; ATP13A2; lysosomal P-type transport ATPase; LRRK2; leuci
Keywords: LS; Lynch syndrome; CRC; colorectal cancer; HNPCC; hereditary non-polyposis colon cancer; MMR; mismatch repair; FAP; familial adenomatous polyposis; CFS; cancer family syndrome; MSI; microsatellite instability; IDL; insertion/deletion loop; MSH2; human mu
Keywords: Parkin; PINK1; Mitophagy; Mitochondrial-derived vesicles; Mitochondrial quality control;
Keywords: PINK1; Parkin; Autophagy; Mitophagy; Parkinson's Disease; Drosophila; DUB;
Keywords: Ambra1; activating molecule in Beclin1-regulated autophagy 1; Atg; autophagy-related protein; BDNF; brain-derived neurotrophic factor; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CREB; cAMP response element-binding; DIC; dynein intermediate
Keywords: 6-OHDA; 6-hydroxydopamine; ADTIQ; 1-acetyl-6, 7-dihydroxyl-1, 2, 3, 4-tetrahydroisoquinoline; AMPK; 5â²-AMP-activated protein kinase; ATF; activating transcription factor 6; ATM; ataxia telangiectasia mutated; CHOP; CCAAT/-enhancer-binding protein homolo
Keywords: Îp; proton motive force established on inner mitochondrial membrane; ÎÏ; electrical membrane potential established on inner mitochondrial membrane; COX4.1; cytochrome c oxidase subunit 4 isoform 1; ERK; extracellular signal-regulated kinase; FA; fatty
Keywords: APAP; acetaminophen; ALD; alcoholic liver disease; BAG4; Bcl2-associated athanogene 4; CCCP; carbonyl-cyanide m-chlorophenyl hydrazine; Clec16a; c-type lectin domain family 16, member A; Dfcp1; double FYVE-containing protein 1; DUB; deubiquitinating enzym
Keywords: AIMP2; aminoacyl-tRNA synthetase complex-interacting multifunctional protein 2; CTX; cerebral cortex; Chow-SN; SN of chow-diet mice; DA; dopaminergic neurons; FBP1; far-upstream element (FUSE) binding protein 1; GO; gene ontology; HFD; high-fat diet; HRP;
Keywords: Energy homeostasis; Mitophagy; PINK1; Parkin; Neurodegenerative diseases; Stress response;
Keywords: Parkinson's disease; Autophagy; Macroautophagy; CMA; α-synuclein; LRRK2; VPS35; PINK1; Parkin; GBA; ATG13A2
Keywords: Parkinson's disease; Parkinsonism; Genetics; SNCA; LRRK2; VPS35; Parkin; PINK1; DJ-1; ATP13A2; PLA2G6; FBXO7; DNAJC6; SYNJ1
Keywords: Ageing; Autophagy; Mitochondria; Mitophagy; Parkin; PGC-1α; PINK1;
Keywords: AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: parkin; PINK1; mitochondria; mitophagy; ubiquitin; E3 ligases
Keywords: Mitochondria; Mitochondrial diseases; Neurodegenerative disorders; Pharmacological neuroprotection; Mitochondrie; Maladies mitochondriales; Maladies neurodégénératives; Neuroprotection pharmacologique; AD; Alzheimer's disease; AICAR; 5-aminoimidazole-4
Keywords: 6-OHDA; 6-hydroxydopamine; AMPK; AMP activated protein kinase; cAMP; cyclic adenosine monophosphate; CAT; catalase; CI; complex I; CII; complex II; CIV; complex IV; COX; cytochrome c oxidase; DMSO; dimethyl sulfoxide; DNP; dinitrophenol; DCF; dichlorodihy
Keywords: Rhomboid protease; Parl; PINK1; Opa1; Hax1; Mitophagy;
Keywords: Akt-GSK3β; Akt-Glycogen Synthase Kinase 3β; ALS; Amyotrophic Lateral Sclerosis; CCCP; Carbonyl cyanide m-chlorophenyl hydrazine; CMT; Charcot-Marie-Tooth; DA; Dopamine; DISC1; Disrupted In Schizophrenia 1; FEZ1; Fasciculation and Elongation Protein-
Keywords: SNc; substantia nigra pars compacta; PD; Parkinson disease; NMS; nonmotor symptoms; MAO-B; monoamine oxidase-B; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxy dopamine; GBA; glucocerebrosidase; STN
Hsp70 participates in PINK1-mediated mitophagy by regulating the stability of PINK1
Keywords: Parkinson's disease; Mitophagy; PINK1; Hsp70;
Skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy
Keywords: Drosophila; Parkinson's disease; PINK1; Mitophagy; Grape skin extract; Resveratrol;
Hepatitis B Virus X protein elevates Parkin-mediated mitophagy through Lon Peptidase in starvation
Keywords: HCC; Hepatocellular Carcinoma; HBV; Hepatitis B virus; HBx; Hepatitis B Virus X protein; PINK1; PTEN Induced Putative Kinase 1; UPRmt; Mitochondrial Unfolded-Protein Response; LONP1; Lon Peptidase 1; EBSS; Earle's balance salt solution; LC3; microtubule-a
PINK1 protects against oxidative stress induced senescence of human nucleus pulposus cells via regulating mitophagy
Keywords: PINK1; Oxidative stress; Senescence; Mitophagy; Intervertebral disc;
Silencing of PINK1 represses cell growth, migration and induces apoptosis of lung cancer cells
Keywords: PINK1; Lung cancer; Apoptosis; Migration; Invasion;
α-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson's disease
Keywords: Parkinson's disease; Neurodegeneration; α-synuclein; C. elegans; Genetics; Animal model; Parkin; PINK1; DJ-1; ATP13A2;
Ameliorating mitochondrial dysfunction restores carbon ion-induced cognitive deficits via co-activation of NRF2 and PINK1 signaling pathway
Keywords: Carbon ions; Cognitive deficits; NRF2; PINK1; Mitochondrial dysfunction; Mitochondrial homeostasis; Redox balance;
Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway
Keywords: PINK1; PTEN-induced kinase 1; i.p.; intraperitoneal; CCA; common carotid artery; ECA; external carotid artery; ICA; internal carotid artery; MCAO; middle cerebral artery occlusion; H&E; haematoxylin and eosin; LC3; Microtubule-associated protein 1 light c