Keywords: پروتئین تیروزین کیناز; Apo; apolipoprotein; BPsys; systolic blood pressure; CS; chondroitin sulfate; CVD; cardiovascular disease; DS; dermatan sulfate; EDTA; ethylene diamine tetraacetic acid; GAG; glycosaminoglycan; HS; heparan sulfate; HSBGF; heparan sulfate-binding growth fa
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Keywords: پروتئین تیروزین کیناز; Cancer; Phytochemical; Radiotherapy; Radioprotection; Side effects; AP-1; activator protein-1; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CAPE; caffeic acid phenylethylester; CAT; chloramphenicol acetyltransferase; CBMN; cytokinesis block
Keywords: پروتئین تیروزین کیناز; α2-MG; α2-macroglobulin; AD; Alzheimer's disease; ERα; estrogen receptor alpha; FASP; filter-aided sample preparation; GHR; growth hormone receptor; GLUT4; glucose transporter 4; GO; gene ontology; LIFR; leukemia inhibitory factor receptor; KEGG; Kyo
Keywords: پروتئین تیروزین کیناز; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CLL; B-cell chronic lymphocytic leukemia; CML; chronic myelogenous leukemia; ERK; extracellular signal-regulated kinase; FN3; fibronectin type-III (domain); GBM; glioblastoma multiforme; JMML
Keywords: پروتئین تیروزین کیناز; PTP; protein tyrosine phosphatase; PTK; protein tyrosine kinase; LMW-PTP; low molecular weight protein tyrosine phosphatase; LMW-AP; low molecular weight acid phosphatase; ACP1; gene coding for human LMW-PTP; PTP1B; tyrosine-protein phosphatase non-recept
Keywords: پروتئین تیروزین کیناز; Cys-loop receptor; Pentameric ligand-gated ion channel; Phosphorylation; Conformational changes; Drug discovery; 5-HT3R; 5-hydroxytryptamine type-3 receptor; CamKII; Ca2+/calmodulin-dependent protein kinase; GABAAR; GABA type-A receptor; GlyR; glycine rec
Keywords: پروتئین تیروزین کیناز; ALI; acute lung injury; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; LPS; lipopolysaccharide; MMP; matrix metalloproteinase; NRTK; nonreceptor tyrosine kinase; PDGF; platelet-derived growth factor; PDGFR; platelet-derived growth fact
A strategy to analyse activity-based profiling of tyrosine kinase substrates in OCT-embedded lung cancer tissue
Keywords: پروتئین تیروزین کیناز; Protein tyrosine kinase; Optimal cutting temperature medium; Lung adenocarcinoma; Protein activity microarrays; Methodology for proteomics;
Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer
Keywords: پروتئین تیروزین کیناز; ADC; adenocarcinoma; ALK; anaplastic lymphoma kinase; CT; computed tomography; HGF; hepatocyte growth factor; IHC; immunohistochemical; KIF5B; kinesin family member 5b; MET; MET proto-oncogene, receptor tyrosine kinase; NSCLC; non-small cell lung cancer;
Targeting phosphatases of regenerating liver (PRLs) in cancer
Keywords: پروتئین تیروزین کیناز; Protein tyrosine phosphatase; Metastasis; Theinopyridone; Structure; CBS; cystathionine-beta-synthase; CHO; Chinese hamster ovary; CNNM; magnesium transporters of cyclin M; EMT; epithelial-mesenchymal transition; HMVEC; human microvascular endothelial c
The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes
Keywords: پروتئین تیروزین کیناز; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt
A change in structural integrity of c-Kit mutant D816V causes constitutive signaling
Keywords: پروتئین تیروزین کیناز; JAK; Janus kinase; JM region; juxtamembrane region; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MD; molecular dynamics; MIHC; Myb-immortalized haemopoietic cells; WT; wild-type c-Kit; WTp; wild-type phosphorylated c-Kit; MT_D816V
The linear structure of β-glucan from baker's yeast and its activation of macrophage-like RAW264.7 cells
Keywords: پروتئین تیروزین کیناز; Yeast β-glucan; Chemical structure; Receptor; Interaction; Activation of microphage-like cells; TNF-α; tumor necrosis factor-α; MIP-2; macrophage inflammatory protein-2; IL; interleukin; MCP-1; monocyte chemotactic protein-1; NF-κB; nuclear factor kap
Candesartan ameliorates arsenic-induced hypertensive vascular remodeling by regularizing angiotensin II and TGF-beta signaling in rats
Keywords: پروتئین تیروزین کیناز; AngII; angiotensin II; ARB; angiotensin receptor blocker; AT1R; AT1 receptor; AT2R; AT2 receptor; CVD; cardiovascular disease; DBP; diastolic blood pressure; CMC; carboxymethyl cellulose; CTGF; connective tissue growth factor; ECM; extracellular matrix; e
Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells
Keywords: پروتئین تیروزین کیناز; Marijuana; Cannabidiol; CYP1A1; Induction; AhR; Protein tyrosine kinase
Cytotoxic activity of T lymphocytes is induced upon stimulation with IL-3 plus GM-CSF in animal leukemia model
Keywords: پروتئین تیروزین کیناز; ENU; N-ethyl-Nâ²-nitrosourea; rmIL-3; recombinant mouse interleukin-3; rmGM-CSF; recombinant mouse granulocyte-macrophage colony-stimulating factor; RT-PCR; real time polymerase chain reaction; PTK; protein tyrosine kinase; IFN-γ; interferon gamma; Leuk
Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium
Keywords: پروتئین تیروزین کیناز; β-AR; beta adrenergic receptor; DCM; dilated cardiomyopathy; ERK; extracellular receptor kinase; PDE4D; 5â²3â² cyclic AMP phosphodiesterase 4D; PKA-C; protein kinase A catalytic subunit; Pln; phospholamaban; Rb; retinoblastoma gene product (pocket prot
Ca2+ signaling in taste bud cells and spontaneous preference for fat: Unresolved roles of CD36 and GPR120
Keywords: پروتئین تیروزین کیناز; Lipids; Taste receptor cells; CD36; GPR120; Stim1; Ca2+ influx factor; Fatty acids; AA; arachidonic acid; [Ca2+]i; free intracellular calcium concentration; CaM; calmodulin; CIF; calcium influx factor; cPLA2; cytosolic phospholipase A2; GL; glossopharynge
A putative role of p53 pathway against impulse noise induced damage as demonstrated by protection with pifithrin-alpha and a Src inhibitor
Keywords: پروتئین تیروزین کیناز; ABR; auditory brainstem response; ANOVA; analysis of variance; DMSO; dimethyl sulfoxide; ECM; extra-cellular matrix; FAK; focal adhesion kinase; OHC; outer hair cell; PBS; phosphate buffered saline; PFT; pifithrin alpha; PI; propidium iodide; PTK; protein
Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity
Keywords: پروتئین تیروزین کیناز; Synthesis; Quinoxalines; Antitumor activity; Cyclooxygenase-2; Docking; Protein tyrosine kinase
Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor
Keywords: پروتئین تیروزین کیناز; AcP; acid phosphatase; AI; androgen-independent; AS; androgen-sensitive; cPAcP; cellular prostatic acid phosphatase; CR PCa; castration-resistant prostate cancer; DSP; dual specificity phosphatase; EGFR; epidermal growth factor receptor; HER-2/ErbB-2/neu;
Modulation of low-voltage-activated T-type Ca2Â + channels
Keywords: پروتئین تیروزین کیناز; LVA; low-voltage-activated; HVA; high-voltage-activated; T-type channels; T-type Ca2Â + channels; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PTK; protein tyrosine kinase; HEK293; human embryo
Differential role of Dok1 and Dok2 in TLR2-induced inflammatory signaling in glia
Keywords: پروتئین تیروزین کیناز; AD; Alzheimer's disease; CNS; central nervous system; DAMPs; damage-associated molecular patterns; Dok; downstream of kinase; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; GM-CSF; granulocyte macrophage colony sti
Molecular identification and expression of Lyn tyrosine kinase isoforms in marsupials
Keywords: پروتئین تیروزین کیناز; Immune signalling; Lyn; Marsupial; Protein tyrosine kinase; Wallaby
Bafetinib inhibits functional responses of human eosinophils in vitro
Keywords: پروتئین تیروزین کیناز; Bafetinib; Eosinophils; Protein tyrosine kinase; Inflammation
Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor
Keywords: پروتئین تیروزین کیناز; Synthesis; Quinoxalines; Epstein–Barr virus; Cancer chemopreventive activity; Docking; Protein tyrosine kinase
Healing the diabetic heart: Does myocardial preconditioning work?
Keywords: پروتئین تیروزین کیناز; I/R; Ischemia-reperfusion; TNF-α; Tumor necrosis factor-alpha; IPC; Ischemic preconditioning; FWOP; First window of protection; SWOP; Second window of protection; TWOP; Third window of protection; eNOS; Endothelial nitric oxide synthase; NO; Nitric oxi
Human ether-Ã -go-go gene potassium channels are regulated by EGFR tyrosine kinase
Keywords: پروتئین تیروزین کیناز; Ion channel modulation; Signal transduction; Protein tyrosine phosphorylation; Protein tyrosine kinase; EGFR kinase;
Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: Suppression of serine/threonine and tyrosine kinases
Keywords: پروتئین تیروزین کیناز; AP-1; activator protein 1; C3-toxin; Clostridium botulinum C3 transferase; CE; cytoplasmic extracts; Cox2; cyclooxygenase 2; ICAM; intercellular adhesion molecule; NF-κB; nuclear transcription factor kappaB; IL; interleukin; IκB; inhibitory subunit of N
Ecdysone receptor and ultraspiracle proteins are tyrosine phosphorylated during adult development of silkmoths
Keywords: پروتئین تیروزین کیناز; Ecdysone; Ecdysone receptor; Ultraspiracle; Protein tyrosine phosphorylation; Protein tyrosine kinase; SilkmothsEcdysone and 20E, 20-hydroxy ecdysone; ecdysteroid, molecules with ecdysone agonist action; EcR, ecdysone receptor; USP, ultraspiracle; TK, tyr
Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch
Keywords: پروتئین تیروزین کیناز; ATTC; American type culture collection; AMAM; anilino-monoindolylmaleimide; CB1; cannabinoid receptor type-1; CB2; cannabinoid receptor type-2; CDx; cluster of differentiation x; CHO; Chinese hamster ovary-K1; CM; cell membrane; CNR1; CB1 receptor gene; C
Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics
Keywords: پروتئین تیروزین کیناز; Akt; protein kinase B; EGFR; epidermal growth factor receptor; ERK; extracellular-regulated kinase; FasL; Fas ligand; JNK; c-Jun N-terminal kinase; MAPK; mitogen activated protein kinase; NF-κB; nuclear factor kappa B; PCD; programmed cell death; PI3K; p
Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity
Keywords: پروتئین تیروزین کیناز; Click chemistry; Triazoles; Src kinase; Protein tyrosine kinase; Structure-activity relationship;
Protein tyrosine kinases in neutrophil activation and recruitment
Keywords: پروتئین تیروزین کیناز; Leukocyte recruitment; Protein tyrosine kinase; Signaling; Integrin
Syk kinase is phosphorylated in specific areas of the developing nervous system
Keywords: پروتئین تیروزین کیناز; ITAM, immunoreceptor tyrosine-based activation motif; DIV, day in vitro; PTK, protein tyrosine kinase; IPL, inner plexiform layer; OB, olfactory bulb; ROS, reactive oxygen speciesSyk; ZAP-70; Protein tyrosine kinase; Brain development; Neuron; Immunorecep
Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics
Keywords: پروتئین تیروزین کیناز; IL-2; interleukin-2; SILAC; stable isotope labeling of amino acids in cell culture; IP; immunoprecipitation; pTyr; phosphotyrosine; PTK; protein tyrosine kinase; JAK; Janus Kinase; MAPK; mitogen-activated protein kinase, SHP-2, SH2-containing phosphatase;
Oxazolone-induced over-expression of focal adhesion kinase in colonic epithelial cells of colitis mouse model
Keywords: پروتئین تیروزین کیناز; IBD, inflammatory bowel disease; PTK, protein tyrosine kinase; FAK, focal adhesion kinaseInflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Protein tyrosine kinase; Focal adhesion kinase
Genistein directly inhibits native and recombinant NMDA receptors
Keywords: پروتئین تیروزین کیناز; Protein tyrosine kinase; Daidzein; Lavendustin; Patch clamp; Hippocampus; HEK293 cells;
Addiction to protein kinase CK2: A common denominator of diverse cancer cells?
Keywords: پروتئین تیروزین کیناز; ALCL; anaplastic large cell lymphoma; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CML; chronic myeloid leukemia; MDR; multi-drug resistance; MM; multiple myeloma; NF-kB; nuclear factor-kB; PDK1; 3â²-phosphoinositide-dependent kinase-1
Electrochemical detection of tyrosine derivatives and protein tyrosine kinase activity using boron-doped diamond electrodes
Keywords: پروتئین تیروزین کیناز; Protein; Boron-doped diamond electrodes; Protein tyrosine kinase; Phosphorylation
Development of the procedures for high-yield expression and rapid purification of active recombinant Csk-homologous kinase (CHK): Comparison of the catalytic activities of CHK and CSK
Keywords: پروتئین تیروزین کیناز; CSK; Protein tyrosine kinase; Src-family kinases; Inhibitor; Tumour suppressor
Synthesis, antitumor activity and molecular docking study of novel Sulfonamide-Schiff's bases, thiazolidinones, benzothiazinones and their C-nucleoside derivatives
Keywords: پروتئین تیروزین کیناز; Sugar-Schiff's base; Thiazolidin-4-one; Benzothiazin-4-one; Antitumor activity; Autodock; Protein tyrosine kinase
A Protein Tyrosine Kinase Inhibitor, Imatinib Mesylate (Gleevec), Improves Erectile and Vascular Function Secondary to a Reduction of Hyperglycemia in Diabetic Rats
Keywords: پروتئین تیروزین کیناز; Diabetic Rat; Erectile Function; Imatinib Mesylate; Platelet-Derived Growth Factor; Protein Tyrosine Kinase; Hyperglycemia; Bcr-Abl;
Protein kinase Cδ and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-κB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro
Keywords: پروتئین تیروزین کیناز; PGN, peptidoglycan; NO, nitric oxide; iNOS, inducible nitric oxide synthase; PKCδ, protein kinase C delta; NF-κB, nuclear factor-κB; LPS, lipopolysaccharide; MΦ, macrophagesPeptidoglycan; iNOS; Protein tyrosine kinase; Protein kinase Cδ; Nuclear factor-κB
Disubstituted pyrimidines as Lck inhibitors
Keywords: پروتئین تیروزین کیناز; Lck; Src; Protein tyrosine kinase; Autoimmune disease; Rheumatoid arthritis; Pyrimidine
Electrochemical detection of protein tyrosine kinase-catalysed phosphorylation using gold nanoparticles
Keywords: پروتئین تیروزین کیناز; Electrochemical biosensor; Colloidal gold nanoparticles; Phosphorylation; Protein tyrosine kinase; Abl-T315I; Staurosporine
The effect of tyrosine kinase inhibitor genistein on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells
Keywords: پروتئین تیروزین کیناز; Genistein; Protein tyrosine kinase; Voltage-dependent K+ channel; Coronary arterial smooth muscle cells
Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist
Keywords: پروتئین تیروزین کیناز; P2X7 receptor; P2Z receptor; ATP; Protein tyrosine kinase; Lymphocyte; Erythrocyte; Human; Canine
A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates
Keywords: پروتئین تیروزین کیناز; Kinase assay; Imatinib mesylate (IM); Peptide substrate; Protein tyrosine kinase
Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosis
Keywords: پروتئین تیروزین کیناز; FAK; focal adhesion kinase; ROS; reactive oxygen species; NAC; N-acetyl-l-cysteine; TM; thimerosal; TSA; thiosalicylic acid; Genis; genistein; Herbim; herbimycin A; HCE; human corneal epithelial; PTK; protein tyrosine kinase; Oxidative stress; Thimerosal;