دانلود مقالات ISI درباره Ptm + ترجمه فارسی

SRp20: An overview of its role in human diseases

Keywords: AS; alternative splicing; PTM; post-translational modifications; RBDs; RNA-binding domains; RRM; RNA recognition motif; RS domain; domain rich in arginine and serine; snRNA; small nuclear RNA; snRNP; small nuclear RiboNucleoProtein; SR-proteins; serine/ar

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

Keywords: HIV-1; human immunodeficiency virus type 1; LTR; long terminal repeats; PTM; post-translational modification; SIRT1; sirtuin 1; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; DMEM; Dulbecco's modified Eagle's mediu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines

Keywords: TNF; Citrullination; Cytokine; IL-1β; Posttranslational modification; Arg; arginine; CHX; cycloheximide; Cit; citrulline; [Cit]TNF-α; citrullinated TNF-α; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immunosorbent assay; E/S; enzy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Quantification of histone modifications using 15N metabolic labeling

Keywords: Ac; acetylation; Pr; propionylation; CV; coefficient of variation; WT; wild-type; KO; knockout; PTM; post-translational modification; HMT; histone methyltransferase; AUC; peak area under the curve; XIC; extracted ion chromatography; Histone; Post-translat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleTGFβ overrides HNF4α tumor suppressing activity through GSK3β inactivation: implication for hepatocellular carcinoma gene therapy

Keywords: TGFβ; transforming growth factor β; EMT; epithelial-to-mesenchymal transition; HCC; hepatocellular carcinoma; HNF4α; hepatocyte nuclear factor 4 alpha; PTM; post-translational modification; GSK3β; glycogen synthase kinase-3 beta; BIO; GSK3β-inhibitor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Constrained selected reaction monitoring: Quantification of selected post-translational modifications and protein isoforms

Keywords: PTM; post-translational modification; MS; mass spectrometry; Erk 1; extracellular-signal-regulated kinase 1; NRGR; neurogranin; TGF-β; transforming growth factor beta; S/N; signal-to-noise ratio; IP; immunoprecipitation; Quantification; Selected reaction

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Formation, signaling functions, and metabolisms of nitrated cyclic nucleotide

Keywords: cGMP; guanosine 3′,5′-cyclic monophosphate; GTP; guanosine 5′-triphosphate; pGC; particulate-type guanylyl cyclase; sGC; soluble-type guanylyl cyclase; 8-Nitro-cGMP; 8-nitroguanosine 3′,5′-cyclic monophosphate; PTM; post-translational modificati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Subunit-specific mass spectrometry method identifies haptoglobin subunit alpha as a diagnostic marker in non-small cell lung cancer

Keywords: Hp; haptoglobin; SID-MRM-MS; stable isotope dilution-multiple reaction monitoring mass spectrometry; CEA; carcinoembryonic antigen; CYFRA 21-1; cytokeratin fragment 19; NSE; neuron specific enolase; ProGRP; pro-gastrin-releasing peptide; NSCLC; non-sm

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP

Keywords: CAD; collisionally activated dissociation; CHO; Chinese hamster ovary; GPI; glycosylphosphatidylinositol; MS; mass spectrometry; MS/MS; tandem mass spectrometry; PRNP; the gene encoding the prion protein; PrPC; cellular prion protein; PrPSc; scrapie isofo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Posttranslational modifications of cardiac troponin T: An overview

Keywords: AMI; acute myocardial infarction; ASK1; apoptosis signal-regulating kinase 1; CaMK II; Ca2 +/calmodulin-dependent protein kinase II; cTnT/I/C; cardiac troponin T, I, C; ESRD; end-stage renal disease; GFC; gel filtration chromatography; HF; heart failure;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Exploring the accessible conformations of N-terminal acetylated α-synuclein

Keywords: αsyn; α-synuclein; Ac-αsyn; acetylated α-synuclein; BOG; beta-octyl glucopyranoside; GST; glutathione S-transferase; CD; circular dichroism; CN-PAGE; clear native PAGE; ESI-MS; electrospray ionization-mass spectrometry; ESI-IMS-MS; electrospray ioni

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Characterisation of the post-translational modifications of a novel, human cell line-derived recombinant human factor VIII

Keywords: α-Gal; Galα1-3Galβ1-GlcNAc-R; Asn/N; asparagine; BHK; baby hamster kidney; CHO; Chinese hamster ovary; EIC; extracted ion chromatogram; FVIII; factor VIII; HA; Haemophilia A; HEK; human embryonic kidney; HexNAcHexNAc; hexosamine-hexosamine; HPAEC-PAD;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes

Keywords: CBS; C/EBPα binding site; C/EBPs; CCAAT/enhancer binding proteins; ChIP; chromatin immunoprecipitation assay; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7α-hydroxylase; FAS; fatty acid synthase; HDAC; histone deacetylase; HFD-MetS; high-fat-diet

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics

Keywords: 2DE; two-dimensional gel electrophoresis; AcK; acetyl-lysine; IEF; isoelectric focusing electrophoresis; LC-MS/MS; liquid chromatography and tandem mass spectrometry; LysAc; lysine acetylation; MALDI-TOF; matrix-assisted laser desorption/ionization- time-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS

Keywords: HPLC-MS/MS; high pressure liquid chromatography-tandem mass spectrometry; ACN; acetonitrile; PEG; polyethylene glycol; BSA; bovine serum albumin; PTM; post translation modification; MS; mass spectrometry; MRM; multiple reaction monitoring; SRM; selective

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

SIR-nucleosome interactions: Structure-function relationships in yeast silent chromatin

Keywords: aa; amino acid; bp; base pairs; ChIP; chromatin immunoprecipitation; EM; electron microscopy; HAT; histone acetyl transferase; HM; homothallic mating-type loci; HMT; histone methyl-transferase; MALS; multi-angle light scattering; NAD; Nicotinamide Adenine

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Functional proteomics approaches for the identification of transnitrosylase and denitrosylase targets

Keywords: 2DE; Two-dimensional gel electrophoresis; ACN; Acetonitrile; BB; Binding buffer; BCA; Bicinchoninic acid; Biotin-HPDP; N-[6-(Biotinamido)hexyl]-3′-(2′-pyridyldithio)-propionamide; BST; Biotin-switch technique; CID; Collision-induced dissociation; DDA;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Volumetric properties underlying ligand binding in a monomeric hemoglobin: A high-pressure NMR study

Keywords: Ce Hb; Chlamydomonas eugametos hemoglobin; cyanomet; ferric protein with cyanide bound; HP; high pressure; MD; molecular dynamics; NMR; nuclear magnetic resonance; GlbN; Synechococcus sp. PCC 7002 hemoglobin; − CN; cyanomet complex; − His; ferric bi

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2013 سفارش ترجمه

Two anti-microtubular drugs for two differential responses: A rice cell line resistant to EPC remains susceptible to oryzalin

Keywords: Carbamates; Dinitroanilines; Herbicides; Cell anisotropy; Microtubules; Rice; Tubulin; EPC; ethyl-N-phenylcarbamate (phenyl urethane); ER31; EPC-resistant mutant 31; ER31d; a rice cell line derived from the ER31 mutant; MAP; microtubule associated protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Signaling pathways that control mRNA turnover

Keywords: PTM; posttranslational modification; ARE; AU-rich elements; UTR; untranslated region; ARE-BP; ARE binding protein; IRE; Iron-responsive element; JRE; Jun-kinase response element; TTP; Tristetraprolin; KSRP; K-homology splicing regulator protein; RISC; RNA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile-The pharmacological importance of post-translational modifications

Keywords: αα; amino acid; CH3CN; acetonitrile; Acm; acetamidomethyl; API; atmospheric pressure ionization; DHB; dihydroxybenzoic acid; cDNA; complimentary DNA; CHCA; α-Cyano-4-hydroxycinnamic acid; CID; collision induced dissociation; DCM; dichloromethane; DIEA;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Advances in purification and separation of posttranslationally modified proteins

Keywords: Posttranslational modification; PTM; Protein enrichment; PTM detection; Proteome; Top-down proteomics

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2013 سفارش ترجمه

Atmospheric pressure photoionization study of post-translational modifications: The case of palmitoylation

Keywords: Photoionization; Mass spectrometry; Palmitoylation; PTM; Tetraspanin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging

Keywords: ALDH2; aldehyde dehydrogenase 2; AMPK; adenosine monophosphate kinase; CREB; cyclic AMP response element binding protein; GNAT; Gcn5-related N-acetyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; LCAD; long chain acetyl-CoA dehydr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers

Keywords: APE1; Apurinic/apyrimidinic endonuclease1; PTM; post-translational modification; nCaRE; negative calcium response elements; BER; base excision repair; TNBC; triple negative breast cancer; PARP; Poly(ADP-ribose) Polymerase; MMS; methyl-methanesulphonate; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of sphingosine kinase 1 regulates cell growth and cell-cycle progression

Keywords: Acetylation; Cell growth; Cell-cycle progression; Sphingosine kinase 1; acetyl-CoA; acetyl coenzyme A; Ad; adenovirus; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; EGFP; enhanced green fluorescent protein; FBS; fetal bovine seru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The UniProtKB/Swiss-Prot Tox-Prot program: A central hub of integrated venom protein data

Keywords: UniProtKB/Swiss-Prot Tox-Prot program; Database; Curation; Venom protein; Animal toxin; Bioinformatics; HGNC; HUGO Gene Nomenclature Committee; INSDC; International Nucleotide Sequence Database Collaboration; IUPHAR; International Union of Basic and Clini

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The PWAPA cassette: Intimate association of a PHD-like finger and a winged-helix domain in proteins included in histone-modifying complexes

Keywords: Sequence analysis; Protein domain; Histone post-translational modifications; PcG; TrxG; ATAC; ASH2; Absent, small or homeotic discs-like 2; ATAC2; ADA2-containing complex; DSB; double strand break; EH; Extended Homology; HAT; histone acetyltransferase; HC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Ventricular restraint therapy for heart failure: A review, summary of state of the art, and future directions

Keywords: 17.1; 22; 38.2; CHF; congestive heart failure; EDD; end-diastolic dimension; EDP; end-diastolic pressure; EDV; end-diastolic volume; EF; ejection fraction; ESV; end-systolic volume; FMR; functional mitral regurgitation; LV; left ventricular, left ventricl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition

Keywords: CDK; Cyclin dependent kinase; CHX; Cycloheximide; CK; Cytokeratin; hnRNP; Heterogeneous nuclear ribonucleoprotein; HU; Hydroxyurea; MCM; Minichromosome maintenance; O-GlcNAc; O-linked beta-N-acetylglucosaminylation; OGA; O-GlcNAcase or beta-N-acetylglucos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Investigation of local primary structure effects on peroxynitrite-mediated tyrosine nitration using targeted mass spectrometry

Keywords: Nitration; Nitrosative stress; Oxidative stress; Tandem mass spectrometry; PTM; MRM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

Keywords: AF1; activation function 1; ANIT; α-naphthylisothiocyanate; AR; androgen receptor; BA; bile acids; BDL; bile duct ligation; ChIP-seq; chromatin immunoprecipitation-sequencing; DBD; DNA binding domain; DR; direct repeat; ER; estrogen receptor; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The application of modular protein domains in proteomics

Keywords: pTyr; phosphotyrosine; PTM; post-translational modification; MS; mass spectrometry; PSSM; position specific scoring matrix; SH2; Src homology 2; SH3; Src homology 3; WW; tryptophan tryptophan; PDZ; post synaptic density protein 95-disks large protein 4-zo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Cone snail milked venom dynamics - A quantitative study of Conus purpurascens

Keywords: Cone snail; Toxins; Conus purpurascens; Envenomation; Conotoxins; Conopeptides; Mass spectrometry; Milked venom; Peptide quantification; Amino acid analysis; Radula harpoon; aq.; aqueous; aq. TFA; Aqueous Trifluroacetic acid; Calc. MH+; Calculated Monoiso

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of the glycated human cerebrospinal fluid proteome

Keywords: AD; Alzheimer's disease; AGEs; Advanced glycation end products; ALS; Amyotrophic lateral sclerosis; BAC; Boronate affinity chromatography; β2M; Beta-2 microglobulin; CID; Collision-induced dissociation; CJD; Creutzfeld-Jakob disease; CML; Nε-(carboxym

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Putting proteins in their place: Palmitoylation in Huntington disease and other neuropsychiatric diseases

Keywords: AD; Alzheimer disease; HD; Huntington disease; PAT; palmitoylacyltransferase; PTM; post-translational modification; TMD; transmembrane domain; PM; plasma membrane; ER; endoplasmic reticulum; Palmitoylation; Huntington disease; HIP14; HIP14L; Palmitoyl acy

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Toward a standardized saliva proteome analysis methodology

Keywords: Whole saliva; LC-MS/MS; Peptidomic; PTM; Proteomics;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

Multiple post-translational modifications in hepatocyte nuclear factor 4α

Keywords: PTM; post-translational modification; HNF4α; hepatocyte nuclear factor 4α; MODY-1; maturity onset diabetes of young 1; DR; direct repeat; ApoCIII; apolipoprotein CIII; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; CID; collisi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Comparison of extraction methods for peptidomics analysis of mouse brain tissue

Keywords: PTM; posttranslational modification; MB; 2-methyl-butane; LN; liquid nitrogen; MW; microwave; TFA; trifluor acetic acid; LC; liquid chromatography; MS; mass spectrometry; Neuropeptide; Mass spectrometry; C57Bl/6J; Sample preparation; Peptide extraction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Investigating a macromolecular complex: The toolkit of methods

Keywords: AUC; analytical ultracentrifugation; ChIP; chromatin immunoprecipitation; co-IP; co-immunoprecipitation; cryoEM; cryoelectron microscopy; cryoET; cryoEM tomography; DSC; differential scanning calorimetry; EPR; electron paramagnetic resonance; FAIM; fluore

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Renewable energy policies and initiatives for a sustainable energy future in Malaysia

Keywords: RE; renewable energy; SREP; small renewable energy power programme; 8MP; Eighth Malaysia Plan; BioGen; biomass generation and demonstration project; GoM; Government of Malaysia; 9MP; Ninth Malaysia Plan; MBIPV; Malaysia building integrated photovoltaic; C

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner

Keywords: BRCT; BRCA1 C-terminus; DDR; DNA damage response; DSB; DNA double-strand break; DUB; deubiquitinase; FHA; forkhead associated; GST; glutathione S-transferase; a.a.; amino acids; NCS; neocarzinostatin; IP; immunoprecipitate; IR; ionizing radiation; PTM; po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Computational approaches to selecting and optimising targets for structural biology

Keywords: MSA; Multiple Sequence Alignment; PTM; Post Translational Modification; SSPF; Scottish Structural Proteomics Facility; MCC; Matthew's correlation coefficient; AROC; Area Under the Receiver Operator Characteristic curve; Target selection; Crystallisation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history

Keywords: Conotoxins; C. californicus; Feeding diversity; cDNA library; RT-PCR; Signal peptides; Cys; cysteine; HPLC; high performance liquid chromatography; MALDI; matrix-assisted laser desorption/ionization; MS; mass spectrometry; PTM; posttranslational modificat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications

Keywords: AEN; aminoethyl nitrate; ALDH; aldehyde dehydrogenase; ALDH1A1; cytosolic aldehyde dehydrogenase; ALDH2; mitochondrial low-Km aldehyde dehydrogenase 2; CYP2E1; ethanol-inducible cytochrome P450 2E1 isozyme; DIGE; fluorescence 2-D difference in gel electro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of novel signaling components in genistein-regulated signaling pathways by quantitative phosphoproteomics

Keywords: SILAC; stable isotope labeling by amino acids in cell culture; PTM; post-translational modification; SCX; strong-cation exchange chromatography; RSD; relative standard deviation; RTKs; receptor tyrosine kinases; GPCRs; G-protein-coupled receptors; BCLAF1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Rapid LC-MS screening for IgG Fc modifications and allelic variants in blood

Keywords: ADCC; antibody dependent cellular cytotoxicity; CV; coefficient of variation; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; Fuc; fucose; GlcNac; N-acetylglucosamine; HC; heavy chain; LC; light chain; mAb; monoclonal antibody; PQA; product qu

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Data processing pipelines for comprehensive profiling of proteomics samples by label-free LC-MS for biomarker discovery

Keywords: 2D-LC-MS; two dimensional liquid chromatography coupled to mass spectrometry; AMT; accurate mass and retention time tag; APEX; absolute protein expression; APML; annotated putative peptide markup language; Cap-LC-MS; LC-MS system equipped with capil

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Multiple γ-glutamylation: A novel type of post-translational modification in a diapausing Artemia cyst protein

Keywords: PSP; phenol soluble protein; PTM; post-translational modification; LEA; late embryogenesis abundant; MALDI-TOF-MS; matrix-associated laser-desorption-ionization time-of-flight mass spectrometry; PTH; phenylthiohydantoin; RACE; rapid amplification of cDNA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

PerspectiveBromodomain Histone Readers and Cancer

Keywords: PTM; post-translational modification; HAT; histone acetyltransferase; HDAC; histone deacetylase; BET; bromodomain and extra-terminal; BRD; bromodomain-containing protein; BRDT; Bromodomain testis associated; NUT; nuclear protein in testis; PROTAC; proteol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه