دانلود مقالات ISI درباره سخت + ترجمه فارسی

Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain

Keywords: سخت; ecstasy; 5-HT; oxidative stress; neurodegeneration; mitochondrial DNA; ALC; acetyl-l-carnitine; ANOVA; analysis of variance; bp; base pairs; BSA; bovine serum albumin; CoA; acetyl-coenzyme A; COXI; cytochrome c oxidase; DNPH; 2,4-dinitrophenylhydrazine; E

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models

Keywords: سخت; ketamine; plus-maze; swim test; anxiety; depression; hippocampal theta; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; ANOVA; analysis of variance; CNS; central nervous system; DAT; dopamine transporter; ECT; electroconvulsive shock therapy; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness

Keywords: سخت; serotonin (5-HT); MWM; locomotor activity; startle; marble burying; CWM; Cincinnati water maze; 5,7-DHT; 5, 7 dihydroxytryptamine; MA; methamphetamine; MWM; morris water maze; P; postnatal day; PCA; p-chloroamphetamine; PCPA; p-chlorophenylalanine; Pet-1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Target site occupancy: Emerging generalizations from clinical and preclinical studies

Keywords: سخت; Target site occupancy; Receptor reserve; Positron Emission Tomography; Single Photon Emission Computed Tomography; G protein-coupled receptor; Target biomarker; BZD; benzodiazepine; CNS; central nervous system; DAT; dopamine transporter; EEDQ; N-ethoxycar

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and serotonin transporter activity of sulphur-substituted α-alkyl phenethylamines as a new class of anticancer agents

Keywords: سخت; SERT; 4-MTA; Antiproliferative activity; Apoptosis; α-Alkylphenethylamine4-MTA, 4-methylthioamphetamine; 5-HT, 5-hydroxytryptamine; ALEPH-2, 1-(2,5-dimethoxy-4-ethylthiophenyl)-2-aminopropane; AMPH, amphetamine; BBB, blood–brain barrier; BCB, blood–cerebr

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2009 سفارش ترجمه

Midbrain serotonin and striatum dopamine transporter binding in double depression: A one-year follow-up study

Keywords: سخت; DAT; Double depression; Dysthymia; Psychotherapy; SERT; SPECT;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Quantitative structure–activity relationship of phenoxyphenyl-methanamine compounds with 5HT2A, SERT, and hERG activities

Keywords: سخت; QSAR; Depression; 5HT2A; SERT; HERG; Conformation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging

Keywords: سخت; SERT; Diphenylsulfide derivatives; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Vulnerability to lasting anxiogenic effects of brief exposure to predator stimuli: Sex, serotonin and other factors—Relevance to PTSD

Keywords: سخت; Amygdala; Anxiety; Cat exposure; Cat odor exposure; Elevated plus maze; Lasting effects; 5-HTT knockout mice; Limbic neuroplasticity; mPFC; Mice; 5-HT1A; 5-HT2A; PTSD; Startle; SERT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Selective serotonin reuptake inhibitors and raft inhibitors shorten the period of Period1-driven circadian bioluminescence rhythms in rat-1 fibroblasts

Keywords: سخت; SSRI; SERT; Lipid raft; Methyl-β-cyclodextrin; Xylazine; Real-time circadian bioluminescence monitoring; Fibroblasts; Mouse suprachiasmatic nucleus;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function

Keywords: سخت; 5-HT; Serotonin; 5-HTT; SERT; 5-HT2A; Genetic variation; Transgenic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Marked decrease of LSD-induced stimulus control in serotonin transporter knockout mice

Keywords: سخت; Lysergic acid diethylamide (LSD); Pentobarbital; Drug discrimination; Mouse; Serotonin transporter; SERT; Knockout

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Serotonin transporter binding and acquired obesity — An imaging study of monozygotic twin pairs

Keywords: سخت; SPECT5; 5-HT; SERT; 5-HTTLPR; radioligand; [123I]nor-β-CIT; twin study; BMI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Validation of a fluorescence-based high-throughput assay for the measurement of neurotransmitter transporter uptake activity

Keywords: سخت; Neurotransmitter; Uptake; DAT; NET; SERT; High-throughput screening; Fluorescence assay

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Estrogen receptor beta in the brain: From form to function

Keywords: سخت; 3β-diol; 5α-androstane-3β,17β-diol; αERKO; estrogen receptor alpha knockout; βERKO; estrogen receptor beta knockout; AA; amino acid; ACTH; adrenocorticotropin hormone; AP-1; activator protein complex-1; AR; androgen receptor; AVP; arginine vasopress

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and characterization of a pegylated derivative of 3-(1,2,3,6-tetrahydro-pyridin-4yl)-1H-indole (IDT199): A high affinity SERT ligand for conjugation to quantum dots

Keywords: سخت; Quantum dots; SERT; Antagonist

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Dual serotonin transporter inhibitor/histamine H3 antagonists: Development of rigidified H3 pharmacophores

Keywords: سخت; Serotonin; Histamine H3; SERT; Tetrahydroisoquinoline

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Acceleration of serotonin transporter transport-associated current by 3,4-methylenedioxymethanphetamine (MDMA) under acidic conditions

Keywords: سخت; MDMA; SERT; Acidic condition; Xenopus oocytes

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET

Keywords: سخت; SERT; PET; Diphenylsulfides; Affinity; Selectivity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Biological evaluation on 125I-ADAM as serotonin transporter ligand

Keywords: سخت; Depression; SERT; ADAM; Imaging agent; Radionuclide imaging; Biodistribution; R817; R749.4;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activity

Keywords: سخت; Histamine; H3; Serotonin; Transporter; SERT; SSRI; Depression; Anti-depressant

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Serotonin Synthesis and Uptake in Symptomatic Patients With Crohn's Disease in Remission

Keywords: سخت; CD; Crohn's disease; CDAI; Crohn's Disease Activity Index; CDEIS; Crohn's Disease Endoscopic Index of Severity; EC; enterochromaffin; GI; gastrointestinal; 5-HT; serotonin; IBD; inflammatory bowel disease; IBS; irritable bowel syndrome; PCR; polymer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain

Keywords: سخت; DAT; dopamine transporter; SERT; 5-HT transporter; NET; norepinephrine transporter; WF-23; 2-β-propanoyl-3-β-(2-naphthyl)tropane; HD-205: 2-β-propanoyl-3-β-(2-naphthyl)-8-[(4-isothiocyanato)benzyl]nortropane; HD-206; 2-β-propanoyl-3-β-(2-naphthyl)-8

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Serotonin transporter density and anxiolytic-like effects of antidepressants in mice

Keywords: سخت; Anxiety; Duloxetine; Fluoxetine; Mouse; NET; Paroxetine; SERT; SNRI; SSRI; Venlafaxine; Zero-maze

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Restoration of 3,4-methylenedioxymethamphetamine-induced 5-HT depletion by the administration of l-5-hydroxytryptophan

Keywords: سخت; amphetamine; ecstasy; 5-HT transporter; RTI-55; binding; DA; dopamine; HPLC-ECD; high pressure liquid chromatography with electrochemical detection; MDMA; (±)-3,4-methylenedioxymethamphetamine; PBS; phosphate-buffered saline; SERT; 5-HT transporter; TP-2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Characterization of a serotonin transporter in the parasitic flatworm, Schistosoma mansoni: Cloning, expression and functional analysis

Keywords: سخت; Serotonin; Transporter; SERT; Biogenic amines; Neurotransmitter; Schistosoma mansoni

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

High Mucosal Serotonin Availability in Neonatal Guinea Pig Ileum Is Associated With Low Serotonin Transporter Expression

Keywords: سخت; EC; enterochromaffin; ENS; enteric nervous system; 5-HIAA; 5-hydroxyindole acetic acid; HPLC; high-performance liquid chromatography; 5-HT; 5-hydroxytryptamine; ir; immunoreactivity; SERT; serotonin transporter; TTX; tetrodotoxin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Population pharmacokinetic model of fluvoxamine in rats: Utility for application in animal behavioral studies

Keywords: سخت; 5-HT; 5-hydroxytryptamine; AUC; area under the curve; BW; bodyweight; CI; confidence interval; CL; systemic clearance; CV; coefficient of variation; CYP; cytochrome P450; DMSO; dimethylsulfoxide; EC50; concentration at the effect site at 50% of the maximu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Architectonic distribution of the serotonin transporter within the orbitofrontal cortex of the vervet monkey

Keywords: سخت; anatomy; cytoarchitecture; serotonergic; ventromedial prefrontal cortex; AChE; acetylcholinesterase; DAB; 3,3′diaminobenzidine; HPLC; high performance liquid chromatography; OFC; orbitofrontal cortex; PFC; prefrontal cortex; ROI; region of interest; SER

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Movement disorders and neurochemical changes in zebrafish larvae after bath exposure to fluoxetine (PROZAC)

Keywords: سخت; Fluoxetine; Zebrafish; Serotonin; SERT; 5-HT1A; Spontaneous swimming

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Expression and immunolocalization of the plasma membrane monoamine transporter in the brain

Keywords: سخت; uptake2; ENT4; brain localization; in situ hybridization; 5-HT; dopamine; CA; field of the hippocampus; DA; dopamine; DAT; dopamine transporter; DIG; digoxigenin; FBS; fetal bovine serum; GFAP; glial fibrillary acidic protein; hPMAT; human plasma membrane

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands

Keywords: سخت; SERT; Diphenylsulfide derivatives; MADAM derivatives; Monoamine transporters

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis and monoamine transporter affinity of 2β-carbomethoxy-3β-(4′-p-substituted phenyl)-piperidine analogs of cocaine

Keywords: سخت; SERT; Monoamine transporter; SPECT; Cocaine; Imaging

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of escitalopram on ethanol withdrawal syndrome in rats

Keywords: سخت; SSRIs; selective serotonin reuptake inhibitors; SERT; 5-HT transporter.; Escitalopram; Ethanol dependence; Ethanol withdrawal syndrome; Rat(s); Selective serotonin reuptake inhibitors (SSRIs);

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Serotonin Transporter Residual Availability During Long-Term Antidepressant Therapy Does Not Differentiate Responder and Nonresponder Unipolar Patients

Keywords: سخت; Depression; beta-CIT; response; antidepressants; SERT; SPECT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

The serotonin transporter in rhesus monkey brain: comparison of DASB and citalopram binding sites

Keywords: سخت; DASB; Citalopram; SSRI; SERT; Autoradiography; Rhesus monkey

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('ecstasy') administration on the dynorphinergic system in the rat brain

Keywords: سخت; opioids; dynorphin A; gene expression; abuse; amphetamine; CP; caudate putamen; CPP; conditioned place preference; CREB; c-AMP responsive element binding protein; DA; dopamine; DAT; dopamine transporter; DYN; dynorphin; HPA; hypothalamic-pituitary-adr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

3-Aza-6,8-dioxabicyclo[3.2.1]octanes as new enantiopure heteroatom-rich tropane-like ligands of human dopamine transporter

Keywords: سخت; DAT; SERT; Tropane; Scaffold

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice

Keywords: سخت; serotonin transporter; 5-HTT; SERT; knockout; behavior; emotionES, embryonic stem; FST, forced swim test; β-gal, β-galactosidase; IRES, internal ribosomal entry site; LTR, long-terminal repeat sequences; NET, norepinephrine transporter; NIH, National Inst

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Alkaloids from Boophane disticha with affinity to the serotonin transporter in rat brain

Keywords: سخت; DPAT; dipropylaminotetralin; SERT; serotonin transporter; SSRI; selective serotonin reuptake inhibitor; Boophane disticha; Buphanamine; Buphanidrine; [3H]-Citalopram; Depression; Radioligand binding assay; Serotonin transporter; 5HT1A;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Screening of traditionally used Lebanese herbs for neurological activities

Keywords: سخت; AChE; acetylcholinesterase; AD; Alzheimer's disease; ATCI; acetylthiocholineiodide; DTNB; 5,5′-dithiobis[2-nitrobenzoic acid; GABA; γ-aminobuturic acid; SERT; serotonin transporter; Acetylcholineseterase; GABA receptor; Lebanese traditional medicine; S

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Mass effect of injected dose in small rodent imaging by SPECT and PET

Keywords: سخت; ADAM; (SERT ligand) 2-[(2-amino-4-iodophenyl)thio]-N,N-dimethyl-benzenemethanamine, [305352-10-7]; CFT; (DAT ligand) 3-[4-(fluoro-18F)phenyl]-8-methyl-, 8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester, (1R,2S,3S,5S)-(WIN35428) [178693-47-5]; DAT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder

Keywords: سخت; ADHD; attention deficit hyperactivity disorder; CREB; cAMP response element binding protein; DA; dopamine; DAT; dopamine transporter; MRI; magnetic resonance imaging; NE; noradrenaline; NET; noradrenaline transporter; SERT; serotonin reuptake transporter;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Psychostimulants and monoamine transporters: upsetting the balance

Keywords: سخت; ADHD; attention deficit hyperactivity disorder; AMPH; amphetamine; CPP; conditioned place preference; DAT; dopamine transporter; KO; knockout; METH; methamphetamine; MDMA; 3,4-methylenedioxymethamphetamine; NET; norepinephrine transporter; PKC; protein ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain

Keywords: سخت; AON; Anterior olfactory nucleus; DASB; 3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile; 5-HT; 5-hydroxytryptamine; NE; norepinephrine; NET; norepinephrine transporter; REM; rapid eye movement; SD; sleep deprivation; SERT; serotonin transport

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome

Keywords: سخت; AUC; area under the curve; C-IBS; constipation-predominant irritable bowel syndrome; D-IBS; diarrhea-predominant irritable bowel syndrome; EC; enterochromaffin cells; 5-HIAA; 5-hydroxindoleacetic acid; 5-HT; 5-hydroxytryptamine; IBS; irritable bowel syndr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Structure-activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor

Keywords: سخت; Trihexyphenidyl; Dopamine; Cocaine; n-methylscopolamine; Transporter; Uptake; Binding; CFT; carboxyfluorotropane; CHO; Chinese hamster ovary; DAT; dopamine transporter; NET; norepinephrine transporter; NMS; n-methylscopolamine; SERT; serotonin transporter

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The influence of Serotonin Transporter Promoter Polymorphism (SERTPR) and other polymorphisms of the serotonin pathway on the efficacy of antidepressant treatments

Keywords: سخت; AD; antidepressant drug; GNB3; G beta3 subunit; HAMD; Hamilton Rating Scale for Depression; AADC; l-Aromatic amino-acid decarboxylase; MAOA; monoamine oxydase A; MAOI; MAO inhibitors; MDE; N-ethyl-3,4-methylenedioxyamphetamine; SD; sleep deprivation; SSRI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Rat brain serotonin neurones that express neuronal nitric oxide synthase have increased sensitivity to the substituted amphetamine serotonin toxins 3,4-methylenedioxymethamphetamine and p-chloroamphetamine

Keywords: سخت; 5-hydroxytryptamine; nitric oxide synthase; ecstasy; 5,7-DHT; serotonin transporter; DRd; dorsomedial subdivision of the dorsal raphé nucleus; DRl; lateral subdivision of the dorsal raphé nucleus; DRv; ventromedial subdivision of the dorsal raphé nucle

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

The Corticotropin-Releasing Factor (CRF)-system and monoaminergic afferents in the central amygdala: Investigations in different mouse strains and comparison with the rat

Keywords: سخت; stress; fear; species differences; in situ hybridization; immunohistochemistry; AP; alkaline phosphate; AStr; amygdalostriatal transition area; BL; basolateral amygdaloid nucleus; Ce; central amygdaloid nucleus; CeL; lateral central amygdaloid nucleus; Ce

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه