دانلود مقالات ISI درباره Sirt1 + ترجمه فارسی

2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside ameliorates vascular senescence and improves blood flow involving a mechanism of p53 deacetylation

Keywords: Stilbene glucoside; Vascular senescence; Sirt1; eNOS; Blood flow;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity

Keywords: SIRT1; Resveratrol; Inducible nitric oxide synthase; Nuclear factor-κB; Articular chondrocytes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Metabolic actions of hypothalamic SIRT1

Keywords: Hypothalamus; SIRT1; aging; metabolism; obesity; diabetes; insulin; skeletal muscle

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells

Keywords: Hematopoietic stem cells (HSCs); SIRT1; FOXO3a; p53; Reactive oxygen species (ROS)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of AMPK–Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects

Keywords: Adipocyte; Adiponectin; AMP-activated protein kinase; Obesity; Peroxisome proliferator-activated receptor-γ; Sirt1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms

Keywords: Resveratrol; SIRT1; NADPH oxidase; Vascular cell senescence

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights

Keywords: SIRT1; FOXO3a; p47phox; Oxidative stress; Resveratrol and diabetes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

MiR-217 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation by down-regulation of SIRT1

Keywords: miR-217; SIRT1; AMPK; NF-κB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression

Keywords: Obesity; Memory; Insulin resistance; Object location memory; SIRT1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewPerspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence

Keywords: SIRT1; Inflammation; Cellular senescence; Telomere attrition; Senescence associated secretory phenotype; DNA damage and repair;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

MicroRNAs in the growth plate are responsive to nutritional cues: association between miR-140 and SIRT1

Keywords: microRNA; Growth plate; Catch-up growth; miR-140; SIRT1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of resveratrol on HepG2 cells as revealed by 1H-NMR based metabolic profiling

Keywords: Resveratrol; HepG2; Sirt1; Metabolic profiling; NMR spectroscopy; Metabolomics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SirT1 in muscle mitochondrial turnover

Keywords: SirT1; AMPK; Nampt; Mitochondrial biogenesis; Autophagy; Circadian rhythm;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Cardiovascular effects and molecular targets of resveratrol

Keywords: 4-HNE; 4-hydroxy-2-nonenal; ADMA; asymmetric dimethylarginine; AMPK; AMP-activated protein kinase; ApoE; apolipoprotein E; ARE; antioxidant response element; BH4; tetrahydrobiopterin; Cav-1; caveolin-1; COX-1; cyclooxygenase 1; CREB; cAMP response element

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1 regulates TNF-α-induced expression of CD40 in 3T3-L1 adipocytes via NF-κB pathway

Keywords: SIRT1; CD40; NF-κB; 3T3-L1 adipocytes; Inflammation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Combined treatment with capsaicin and resveratrol enhances neuroprotection against glutamate-induced toxicity in mouse cerebral cortical neurons

Keywords: ROS; reactive oxygen species; SOD1; copper/zinc superoxide dismutase; SOD2; manganese SOD; GPx1; cytoplasmic glutathione peroxidase; CNS; central nervous system; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor-α; SIRT1; silent mating type informat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Herbal medicines for the prevention of alcoholic liver disease: A review

Keywords: ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; CAT; catalase; COX-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Amurensin G, a novel SIRT1 inhibitor, sensitizes TRAIL-resistant human leukemic K562 cells to TRAIL-induced apoptosis

Keywords: TRAIL; Amurensin G; SIRT1; c-Myc; K562 cells;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Region-specific changes in the immunoreactivity of SIRT1 expression in the central nervous system of SOD1G93A transgenic mice as an in vivo model of amyotrophic lateral sclerosis

Keywords: Amyotrophic lateral sclerosis (ALS); SOD1G93A transgenic mice; SIRT1; Cerebral cortex; Hippocampus; Thalamus

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The protective effect of resveratrol on islet insulin secretion and morphology in mice on a high-fat diet

Keywords: Resveratrol; High fat diet; Diabetes; Islet beta cell; SIRT1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol as a calorie restriction mimetic: therapeutic implications

Keywords: resveratrol; PDE; AMPK; Sirt1; calorie restriction; diabetes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis

Keywords: AdipoR; adiponectin receptor; AMPK; 5′-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo

Keywords: SIRT1; ERK; Salermide; Traumatic brain injury; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Porphyromonas gingivalis lipopolysaccharide regulates interleukin (IL)-17 and IL-23 expression via SIRT1 modulation in human periodontal ligament cells

Keywords: P. gingivalis; LPS; IL-17; IL-23; SIRT1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The role of sirtuins in modulating redox stressors

Keywords: SIRT1; SIRT3; Sirtuins; Mitochondria; Redox stress; Resveratrol; Metabolism; Free radicals

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction

Keywords: FFA; free fatty acid; PDX1; pancreatic and duodenal homeobox 1; GSIS; glucose-stimulated insulin secretion; JNK; Jun N-terminal kinase; SIRT1; sirtuin 1; PGC-1; peroxisome proliferator-activated receptor gamma coactivator 1; NeuroD; neurogenic differentia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death

Keywords: Resveratrol; SIRT1; Prion disease; PrP (106–126); Neuronal apoptosis; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

Keywords: Metabolic syndrome; Berberine; Mitochondria; SIRT1; AMPK; NAMPT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart

Keywords: Sirt1; Dilated cardiomyopathy; Mitochondrial dysfunction; Mef2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast

Keywords: Osteoblast; Differentiation; Insulin; Akt; Adipocytes; Sirt1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Tumor suppressor genes and ROS: complex networks of interactions

Keywords: ATM; ataxia telangiectasia mutated protein; BRCA; breast cancer susceptibility gene; CAT; catalase; CDK; cyclin-dependent kinase; FoxO; class O forkhead box transcription factors; GLS2; glutaminase; GPX; glutathione peroxidase; GSH; glutathione; JNK; Jun

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

Keywords: Aging; Autophagy; AMPK; Longevity; NF-κB; SIRT1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Proteases involved in cartilage matrix degradation in osteoarthritis

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; APC; activated protein C; CITED2; cAMP-responsive element-binding protein/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; ECM; extracellular matrix; ERK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis

Keywords: Akt/PKB; acutely transforming retrovirus AKT8 in rodent T cell lymphoma/protein kinase B; AMPK; AMP-activated protein kinase; CBP; CREB-binding protein; C/EBP; CCAAT enhancer binding protein; CNS; central nervous system; CREB; cAMP-responsive binding prot

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence

Keywords: mTOR; SIRT1; Mesangial cells; Senescence; High glucose

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacological targets in the renal peritubular microenvironment: Implications for therapy for sepsis-induced acute kidney injury

Keywords: AKI; acute kidney injury; RBF; renal blood flow; MAP; mean arterial pressure; GFR; glomerular filtration rate; LPS; lipopolysaccharide; CLP; cecal ligation and puncture; MMP; matrix metalloproteinase; S1P; sphingosine-1-phosphate; S1PR; sphingosine-1-phos

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury

Keywords: aldosterone; mitochondrial dysfunction; podocytes; SIRT1

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy

Keywords: SIRT1; Cardiac hypertrophy; HDACs; Resveratrol

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells

Keywords: Sirt1; Human embryonic stem cell; Motoneuron differentiation; Motoneuron disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

The role of microRNAs in modulating sirtuin 1 expression

Keywords: MicroRNA; p53; SIRT1; Sirtuin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Upregulation of SIRT1 deacetylase in phenylephrine-treated cardiomyoblasts

Keywords: SIRT1; AMP-activated Protein Kinase (AMPK); Cardiac hypertrophy; Phenylephrine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

Keywords: SIRT1; Type 2 diabetes; Insulin secretion; Genetic associations;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats

Keywords: Insulin secretion; SIRT1; SIRT4; Caloric restriction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

Keywords: Aging; Longevity; SIRT1; NAMPT; NAD biosynthesis; NAD World

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis

Keywords: ALS; amyotrophic lateral sclerosis; VSC 4.1; ventral spinal cord 4.1 cells; hSOD1; human superoxide dismutase 1; wt; wild type; SIRT1; silent mating type information regulation 2 homolog 1; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Insulin downregulates SIRT1 and AMPK activation and is associated with changes in liver fat, but not in inflammation and mitochondrial oxidative capacity, in streptozotocin-diabetic rat

Keywords: Insulin; Liver; Diabetes; SIRT1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Post-translational modification of pregnane x receptor

Keywords: PXR; pregnane x receptor; NR; nuclear receptor; PCN; pregnenalone 16α-carbonitrile; Rif; rifampicin; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenolpyruvate carboxykinase; CYP3A; cytochrome P450 3A; CREs; cyclic AMP response elements; PKA; cyclic AMP-d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1

Keywords: EVI1; SIRT1; PCAF; Deacetylation; CML

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Food restriction improves glucose and lipid metabolism through Sirt1 expression: A study using a new rat model with obesity and severe hypertension

Keywords: Obesity; Food restriction; Sirt1; PPAR; Adipocytokine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه