Keywords: تداخل کوچک RNA; EU; European Union; FDA; Food and Drug Administration; EMA; European Medicines agency; HEK; human embryonic kidney; shRNA; short hairpin RNA; siRNA; small interference RNA; α-gal; galactose-α1,3-galactose; Neu5Gc; N-glycolylneuraminic acid; IgG; Immunog
مقالات ISI تداخل کوچک RNA (ترجمه نشده)
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Keywords: تداخل کوچک RNA; ABCB5; ATP-binding cassette member B5; dFb; dermal fibroblasts; GM-CSF; colony-stimulating factor granulocyte macrophage; MSC; mesenchymal stromal cell; PGD2; prostaglandin-D2; PGE2; prostaglandin-E2; siRNA; small interference RNA; SN; supernatant; TG; th
Keywords: تداخل کوچک RNA; H3K4me3; tri-methylations at histone H3 Lysine 4; ChIP-seq; chromatin immunoprecipitation and sequencing; siRNA; small interference RNA; Chromatin remodeling; Chromatin modifications; Epigenomics; Computational analysis;
Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis
Keywords: تداخل کوچک RNA; HCC; hepatocellular carcinoma; TRIM31; tripartite motif 31; AMPK; AMP-activated protein kinase; RPMI; Roswell Park Memorial Institute; DMEM; Dulbecco's modified Eagle's medium; Poly-HEMA; poly-(2-hydrocyethyl methacrylate); PBS; phosphate-buffered saline;
Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A
Keywords: تداخل کوچک RNA; CDSN; corneodesmosin; PSS; peeling skin syndrome; siRNA; small interference RNA;
MiR-767 promoted cell proliferation in human melanoma by suppressing CYLD expression
Keywords: تداخل کوچک RNA; miRNA; microRNA; siRNA; small interference RNA; CYLD; cylindromatosis; MiR-767-in; miR-767 inhibitor; PEM; Primary Human Epidermal Melanocytes; FBS; fetal bovine serum; DMSO; dimethyl sulphoxide; PBS; phosphate-buffered saline; PVDF; polyvinylidene difluo
Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages
Keywords: تداخل کوچک RNA; LXR; liver X receptor; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SREBP1c; sterol response element binding protein 1c; AMPK; AMP-activated protein kinase; PMA; phorbol myristate acetate; fMLP; formyl-Met-Leu-Ph
Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells
Keywords: تداخل کوچک RNA; Gastric cancer; saRNA; VEZT; Invasion; Migration; dsControl; double stranded control; dsRNA; double stranded RNA; GC; gastric cancer; VEZT; vezatin; RNAa; RNA activation; RNAi; RNA interference; saRNA; small activating RNA; siRNA; small interference RNA;
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells
Keywords: تداخل کوچک RNA; ABC; ATP-binding cassette; ABCC; The ABC subfamily C; ABCC1; ATP-binding cassette subfamily C member 1; AHR; aryl hydrocarbon receptor; AKR1C1; aldo-keto reductase family 1 member C1; AREs; antioxidant-responsive elements; B-Raf; B-Raf proto-oncogene, ser
Modulating angiogenesis with integrin-targeted nanomedicines
Keywords: تداخل کوچک RNA; (RGD)m; RGD mimetics; 4-NQO; 4-nitroquinoline 1-oxide; AAA; Abdominal Aortic Aneurysms; ADA; 8-Amino-3,6-Dioxaoctonoic Acid; AH-GDM; Aminohexyl-Geldanamycin; ami; Amide; AP-2α; Activating Protein 2α; ARMS; Alveolar Rhabdomyosarcoma; ATO; Arsenic Trioxid
Functional relevance of miRNAs in premature ageing
Keywords: تداخل کوچک RNA; CRP; C-reactive protein; DDR; DNA damage response; DSB; double-strand breaks; HATs; histone acetyltransferases; HDACs; histone deacetylases; hMSCs; human mesenchymal stem cells; HRR; homologous recombination repair; MEFs; mouse embryonic fibroblast; ROS;
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase
Keywords: تداخل کوچک RNA; ApoEÂ â/â; Â ApoE deficient; EBM-2; endothelial basal medium-2; EC; endothelial cells; EDN; endothelial human Nox4DN transgenic mice; EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; FBS; fetal bovine serum; HAEC; human aortic
Akt phosphorylates myc-associated zinc finger protein (MAZ), releases P-MAZ from the p53 promoter, and activates p53 transcription
Keywords: تداخل کوچک RNA; p53; Arf; Mdm2; Akt; MAZ; Phosphorylation; ChIP; chromatin immunoprecipitation; Dox; doxycycline; EMSA; electrophoretic mobility shift assay; IB; immunoblotting; IP; immunoprecipitation; Myr-Akt; myristoylatedAkt; siRNA; small interference RNA; WB; Wester
Heme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunction
Keywords: تداخل کوچک RNA; PI; protease inhibitors; ROS; reactive oxygen species; HO-1; heme oxygenase-1; CO; carbon monoxide; CORM2; carbon monoxide releasing molecule-2; iCORM2; inactivated carbon monoxide releasing molecule-2; CM-H2DCFDA; 5-(and-6)-chloromethyl-2,7-dichlorodihyd
Reversal of chemoresistance with small interference RNA (siRNA) in etoposide resistant acute myeloid leukemia cells (HL-60)
Keywords: تداخل کوچک RNA; ABCB1 gene; Etoposide; Chemosensitivity; Drug resistance; HL-60 cell; Small interference RNA
Research paperHuman cytomegalovirus microRNA miR-US25-1-5p inhibits viral replication by targeting multiple cellular genes during infection
Keywords: تداخل کوچک RNA; miRNAs; microRNAs; HCMV; human cytomegalovirus; siRNA; small interference RNA; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; MEM; minimal essential medium; MOI; multiplicity of infection; hpi; hours post infection; RT; reverse transcr
Commitment of Annexin A2 in recruitment of microRNAs into extracellular vesicles
Keywords: تداخل کوچک RNA; miRNA; microRNA; EV; extracellular vesicle; qRT-PCR; quantitative RT-PCR; siRNA; small interference RNA; RNase; âribonuclease; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; ANXA1; Annexin A1; ANXA2; Annexin A2; ANXA5; Annexin A5; ANXA6; Annexin A6; E
Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation
Keywords: تداخل کوچک RNA; 3-Methyladenine (Pubmed CID 1673); Camptothecin (Pubmed CID 24360); Etoposide (Pubmed CID 36462); 7-Bromoindirubin-3-oxime (Pubmed CID 11846148); Necrostatin-1 (Pubmed CID 282833); Q-VD-OPh (Pubmed CID 11237609); 2-Phenylethynesulfonamide (Pubmed CID 3276
Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway
Keywords: تداخل کوچک RNA; 6-OHDA; 6-hydroxydopamine; ARE; antioxidant response element; BSA; bovine serum albumin; Cyt C; cytochrome c; DA; dopamine; DAPI; 4â²,6-diamidino-2-phenylindole; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; DOPAC; dih
Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons
Keywords: تداخل کوچک RNA; BH domain; Bcl-2 homology domain; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; CHX; cycloheximide; CREB; cAMP-response element-binding protein; DIV; days-in-vitro; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FC
CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells
Keywords: تداخل کوچک RNA; bHLH; basic helix-loop-helix; csh; control shRNA; csi; control siRNA; FAS1; fasciclin I; CD26/10Chi; stable transfectant of MPM cell line, MSTO-211H with CD26-CD10 chimeric receptor; CD26WT; stable transfectant of MPM cell line, MSTO-211H with a full-le
Orphan nuclear receptor Nur77 is a novel negative regulator of endothelin-1 expression in vascular endothelial cells
Keywords: تداخل کوچک RNA; ET-1; endothelin-1; qRT-PCR; quantitative real-time PCR; HUVEC; human umbilical vein endothelial cell; EMSA; electrophoretic mobility shift assay; siRNA; small interference RNA; NBRE; Nur77-binding response element; 6-MP; 6 mercaptopurine; ELISA; enzyme-l
Mature miR-183, negatively regulated by transcription factor GATA3, promotes 3T3-L1 adipogenesis through inhibition of the canonical Wnt/β-catenin signaling pathway by targeting LRP6
Keywords: تداخل کوچک RNA; C/EBPα, β, δ; CCAAT/enhancer binding protein α, β, δ; PPARγ; peroxisome proliferator-activated receptor γ; FAS; fatty acid synthase; ap2; adipocyte fatty acid binding protein; LRP5/6; low-density lipoprotein receptor-related protein 5/6; GSK3β; g
Far-infrared radiation acutely increases nitric oxide production by increasing Ca2+ mobilization and Ca2+/calmodulin-dependent protein kinase II-mediated phosphorylation of endothelial nitric oxide synthase at serine 1179
Keywords: تداخل کوچک RNA; FIR; far-infrared; eNOS; endothelial nitric oxide synthase; eNOS-Ser1179; eNOS at serine 1179; EC; endothelial cell(s); NO; nitric oxide; AMPK; AMP-activated protein kinase; CaMKII; Ca2+/calmodulin-dependent protein kinase II; PKA; protein kinase A; BAEC;
B56α subunit of protein phosphatase 2A mediates retinoic acid-induced decreases in phosphorylation of endothelial nitric oxide synthase at serine 1179 and nitric oxide production in bovine aortic endothelial cells
Keywords: تداخل کوچک RNA; eNOS; endothelial nitric oxide synthase; EC; endothelial cell(s); NO; nitric oxide; AMPK; AMP-activated protein kinase; CaMKII; calmodulin-dependent kinase II; PKA; protein kinase A; atRA; all-trans retinoic acid; PP; protein phosphatase; PP2A Cα; cataly
Hepatitis B virus X protein protects hepatoma and hepatic cells from complement-dependent cytotoxicity by up-regulation of CD46
Keywords: تداخل کوچک RNA; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; mCRPs; membrane-bound complement regulatory proteins; CDC; complement-dependent cytotoxicity; COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; CREB; cAMP response element-binding protein; RN
Knockdown of TIGAR by RNA interference induces apoptosis and autophagy in HepG2 hepatocellular carcinoma cells
Keywords: تداخل کوچک RNA; siRNA; small interference RNA; RNAi; RNA interference; HCC; hepatocellular carcinoma; ROS; reactive oxygen species; TIGAR; TP53-induced glycolysis and apoptosis regulator; siTIGAR; siRNA for TIGAR; TIGAR; Apoptosis; Autophagy; Hepatocellular carcinoma; RN
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway
Keywords: تداخل کوچک RNA; AGE; Advanced glycation end product; AP-1; Activator protein 1; BUN; Blood urea nitrogen; Cr; Serum creatinine; Cur; Curcumin; DN; Diabetic nephropathy; ECM; Extracellular matrix; FBG; Fasting blood glucose; FN; Fibronectin; GBM; Glomerular basement membr
Lipid raft regulates the initial spreading of melanoma A375 cells by modulating β1 integrin clustering
Keywords: تداخل کوچک RNA; ECM; extracellular matrix; MβCD; methyl-β-cyclodextrin; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; MES; 4-morpholineethanesulfonic acid; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; CTXB; cholera toxin subun
The Orosomucoid 1 protein is involved in the vitamin D - mediated macrophage de-activation process
Keywords: تداخل کوچک RNA; AF2; Activation function domain 2; AGP-A; Alpha 1 acid glycoprotein A; AKNA1; AT-Hook Transcription Factor 1; CAMP; Cathelicidin Antimicrobial Peptide; CB; Cord Blood; COL27A1; Collagen, Type XXVII, alpha-1; MMP9; Matrix Metalloproteinase 9; MRC1; Mannose
RNAi: antiviral therapy against dengue virus
Keywords: تداخل کوچک RNA; Dengue virus; Dengue haemorrhagic fever; RNA interference; Small interference RNA;
Serotonin 5-HT2A receptor-mediated hypertrophy is negatively regulated by caveolin-3 in cardiomyoblasts and neonatal cardiomyocytes
Keywords: تداخل کوچک RNA; 5-HT; Serotonin; NFAT; nuclear factor of activated T cells; p42/p44 MAPK; p42/p44 mitogen activated protein kinases; siRNA; small interference RNA; ANF; atrial natriuretic factor; β-MHC; β-myosin heavy chain; GPCR; G-protein coupled receptor; TRPC1; tra
Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo
Keywords: تداخل کوچک RNA; Lung cancer; Insulin-like growth factor 1 receptor; Small interference RNA; Liposomal magnetofection; Magnetic lipoplexes
Downregulation of nuclear factor-κB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer
Keywords: تداخل کوچک RNA; Pancreatic cancer; Nuclear factor-κB; Gemcitabine; Small interference RNA
The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity
Keywords: تداخل کوچک RNA; CPU; caudate putamen; DA; Dopamine; GFP; green fluorescent protein; HEK293T; human embryonic kidney 293T cells; NAc; nucleus accumbens; qRT-PCR; quantitative real-time polymerase chain reaction; shRNA; short hairpin RNA; siRNA; small interference RNA; VTA
Up-regulation of Krüppel-Like Factor 8 Promotes Tumor Invasion and Indicates Poor Prognosis for Hepatocellular Carcinoma
Keywords: تداخل کوچک RNA; Small Interfering RNA; siRNA; Liver Cancer; Metastatic Liver Cancer; Tumor Microenvironment; AFP; α-fetoprotein; ALT; alanine aminotransferase; BCLC; Barcelona Clinic Liver Cancer; cDNA; complementary DNA; ChIP; chromatin immunoprecipitation; EMT; epithe
Toxoplasma gondii: siRNA can mediate the suppression of adenosine kinase expression
Keywords: تداخل کوچک RNA; Apicomplexa; Adenosine kinase (EC 2.7.1.20); Toxoplasma; Small interference RNA; AK, adenosine kinase; dsRNA, double-stranded RNA; HFF, human foreskin fibroblasts; HXGPRT, hypoxanthine–guanine–xanthine phosphoribosyltransferase; RNAi, RNA interference; RT
Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells
Keywords: تداخل کوچک RNA; Sugar cataract; Aldose reductase; Rat lens epithelial cell; Small interference RNA; Aldose reductase inhibitor
Hydrocortisone Modulates Cholera Toxin Endocytosis by Regulating Immature Enterocyte Plasma Membrane Phospholipids
Keywords: تداخل کوچک RNA; CT; cholera toxin; DIGs; detergent insoluble glycolipids/rafts; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; H4; a primary human fetal crypt small intestinal cell line; HC; hydrocortisone succinate; hIEC; freshly isolated human small intestinal epithe
Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme
Keywords: تداخل کوچک RNA; Allergic asthma; GATA-3; DNAzymes; TH2 cells; antisense DNA; small interference RNA; AHR; Airway hyperresponsiveness; asDNA; Antisense DNA; BAL; Bronchoalveolar lavage; BDNF; Brain-derived neurotrophic factor; FACS; Fluorescence-activated cell sorting; HE
Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma
Keywords: تداخل کوچک RNA; Alb-Cre; albumin promoter-driven Cre-recombinase; AR; androgen receptor; BrdU; 5'-bromo-2'-deoxyuridine; DEN; N'-N'-diethylnitrosamine; DHT; 5α-dihydrotestosterone; L-AR-/y; conditional knockout AR mouse lacking only the hepatic AR; MTT; 3-(4,5-dimethy
Cooperative activation of lipocalin-type prostaglandin D synthase gene expression by activator protein-2β in proximal promoter and upstream stimulatory factor 1 within intron 4 in human brain-derived TE671 cells
Keywords: تداخل کوچک RNA; PG; prostaglandin; L-PGDS; lipocalin-type PGD synthase; AP; activator protein; USF; upstream stimulatory factor; UTR; untranslated region; EMSA; electrophoretic mobility shift assay; ChIP; chromatin immunoprecipitation; siRNA; small interference RNA; N.C.
Smad3 mediates TGF-β1-induced collagen gel contraction by human lung fibroblasts
Keywords: تداخل کوچک RNA; Small interference RNA; Smad3; Transforming growth factor-β1; Fibroblast
Kinectin participates in microtubule-dependent hormone secretion in pancreatic islet β-cells
Keywords: تداخل کوچک RNA; Kinectin; Intracellular transport; Amylin; Hormone secretion; Islet β-cells; ER; endoplasmic reticulum; KHC; kinesin heavy chain; KNT; kinectin; RNAi; RNA interference; siRNA; small interference RNA;
Smad3 mediates TGF-β1 induction of VEGF production in lung fibroblasts
Keywords: تداخل کوچک RNA; Small interference RNA; Smad2; Smad3; Transforming growth factor-β1; Vascular endothelial growth factor;
Microfibril-associated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro
Keywords: تداخل کوچک RNA; GAPDH; glyceroaldehyde-3-phosphate dehydrogenase; HGF; human gingival fibroblasts; MAGP; microfibril-associated glycoprotein; MEM; minimum essential medium; siRNA; small interference RNA; Elastin deposition; Elastogenesis; Fibrillin; MAGP; Tropoelastin;
The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells
Keywords: تداخل کوچک RNA; hRR; human ribonucleotide reductase; hRRM1; human ribonucleotide reductase large subunit M1; hRRM2; human ribonucleotide reductase small subunit M2; M2B; a p53-dependent human ribonucleotide reductase small subunit M2B, it also called p53R2; RNR; yeast ri
Novel Experimental Therapeutic Approaches for Prostate Cancer
Keywords: تداخل کوچک RNA; AR; androgen receptor; ASO; antisense oligodeoxynucleotide; HRPC; hormone refractory prostate cancer; siRNA; small interference RNA; RISC; RNA inducing silencing complex; Prostate cancer; Androgen receptor; Antisense; siRNA; Apoptosis; Prodrug; Chimeric a
17β-estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuropro
Keywords: تداخل کوچک RNA; neuroprotective mechanisms; gonadal-steroids; calcium-channels; signaling-cascades; estrogen membrane receptor; AgTx IVA; Ï-agatoxin IVA; Akt; protein kinase B; [Ca2+]i; intracellular Ca2+ concentration; CaMKII; calcium-calmodulin kinase II; CgTx GVIA;