Keywords: شاخص تحریک; Anaphylaxis; Basophil activation test; Drug allergy; Platinum compounds; Rapid drug desensitization; BAT; Basophil activation test; BTR; Breakthrough reaction; DHR; Drug hypersensitivity reaction; gMFI; Geometric mean fluorescence intensity; RDD; Rapid dr
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Keywords: شاخص تحریک; Con A; Concanavalin A; MADRS; Montgomery-Ã
sberg Depression Rating Scale; MDCS; Myeloid-Derived Suppressor Cell; MDD; Major Depressive Disorder; Pha; Phytohaemagglutinin; PKW; Pokeweed Mitogen; SAD; Seasonal Affective Disorder; SI; Stimulation Index;
Keywords: شاخص تحریک; Metal sensitization; Nickel; Cobalt; Chromium: Bone cement; Methacrylates; Patch testing; Joint replacements; Orthopedic implants; LPT; lymphocyte proliferation test; MMA; methyl methacrylate; PMMA; polymethyl methacrylate; SI; stimulation index; TLR4; To
Keywords: شاخص تحریک; Chronic granulomatous disease; dihydrorhodamine-1,2,3 assay; CYBB; CYBA; NCF1; NCF2; nicotinamide dinucleotide phosphate reduced oxidase; mean fluorescence intensity; stimulation index; AR; Autosomal recessive; A22R; A22 CGD with residual oxidase activity
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates
Keywords: شاخص تحریک; EndoC-βH1; Pseudoislets; Glucose stimulated insulin secretion; Somatostatin signaling; Proliferation; BB; Bombesin; PACAP; Pituitary Adenylate Cyclase-Activating Polypeptides; SST; Somatostatin; Bxv1; B10 xenotropic virus 1; GLP1R; GLP1 receptor; GSIS; G
Procedures for leukocytes isolation from lymphoid tissues and consequences on immune endpoints used to evaluate fish immune status: A case study on roach (Rutilus rutilus)
Keywords: شاخص تحریک; Fish; Leukocytes; Cell isolation; Density gradient; Erythrocytes lysis; Immunity; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; DG; density gradient; FCS; foetal calf serum; HL; hypotonic lysis; P/S; Penicillin/Streptomycin; PBS; Phosphate Buffer Salin
Evaluation of 4-methylcyclohexanemethanol (MCHM) in a combined irritancy and Local Lymph Node Assay (LLNA) in mice
Keywords: شاخص تحریک; 4-Methylcyclohexanemethanol; Local Lymph Node Assay (LLNA); Allergic contact; Dermatitis (ACD); Dermal hypersensitivity; Dermal irritancy; Elk River spill; ACD; allergic contact dermatitis; AOO; acetone:olive oil (4:1, v/v); CDC; Centers for Disease Contr
Oral administration of synthetic selenium nanoparticles induced robust Th1 cytokine pattern after HBs antigen vaccination in mouse model
Keywords: شاخص تحریک; HBV; hepatitis B virus; HBsAg; hepatitis B surface antigen; SeNPs; selenium nanoparticles; ELISA; enzyme-linked immunosorbent assay; PBS; phosphate buffered saline; CHB; chronic hepatitis B; LC; liver cirrhosis; HCC; hepatocellular carcinoma; HEPES; 4-2-h
Comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references
Keywords: شاخص تحریک; Ac; Acylating agents; ACD; Allergic Contact Dermatitis; AOP; Adverse Outcome Pathway; ARE; Antioxidant Response Element; DC; dendritic cell; DMSO; dimethyl sulfoxide; DNCB; dinitrochlorobenzene; DPRA; Direct Peptide Reactivity Assay; ECVAM; European Centr
In vitro safety and efficacy evaluations of a complex botanical mixture of Eugenia dysenterica DC. (Myrtaceae): Prospects for developing a new dermocosmetic product
Keywords: شاخص تحریک; AAAPVN; N-succinyl-ala-ala-ala-p-nitroanilide; BCOP; Bovine Corneal Opacity and Permeability; CBPI; cytokinesis-block proliferation index; CV80; non-cytotoxic concentration of test substance that maintain cell viability â¥Â 80%; DNCB; 1-chloro-2,4-dinitr
Assessment of lymphocyte proliferation for diagnostic purpose: Comparison of CFSE staining, Ki-67 expression and 3H-thymidine incorporation
Keywords: شاخص تحریک; PHA; phytohemagglutinin; PBMC; peripheral blood mononuclear cells; CFSE; carboxy fluorescein succinimidyl ester; BrdU; 5-bromo-2-deoxyuridine; CPM; counts per minute; SI; stimulation index; FASCIA; Flow-cytometric assay for specific cell-mediated immune-r
Analysis of the Local Lymph Node Assay (LLNA) variability for assessing the prediction of skin sensitisation potential and potency of chemicals with non-animal approaches
Keywords: شاخص تحریک; ACE; acetone; AOO; acetone:olive oil (4:1 by volume); DMF; dimethylformamide; EC3; effective concentration inducing a stimulation index of 3; ETOH/DEP; Ethanol/diethylphthalate; EXT; extreme (ECETOC classification); IDR; Insufficient Dose Response; MOD; m
A suicidal DNA vaccine expressing the fusion protein of peste des petits ruminants virus induces both humoral and cell-mediated immune responses in mice
Keywords: شاخص تحریک; BHK-21 cell; baby hamster kidney; CPE; cytopathic effect; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; DIVA; differentiating infected from vaccinated animals; DMEM; Dulbecco's modified Eagle's medium; F protein; fusion protein; GMT; geometric mean tit
Phlebotomus papatasi exposure cross-protects mice against Leishmania major co-inoculated with Phlebotomus duboscqi salivary gland homogenate
Keywords: شاخص تحریک; DUB; Phlebotomus duboscqi; EXP; exposed; L.; Leishmania; Lu.; Lutzomyia; NB; nitrocellulose membrane; nEXP; non-exposed; P.; Phlebotomus; p.i.; post infection; PAP; Phlebotomus papatasi; PMΦ; peritoneal macrophages; SGH; salivary gland homogenate; SI; st
Mannan-conjugated myelin peptides prime non-pathogenic Th1 and Th17 cells and ameliorate experimental autoimmune encephalomyelitis
Keywords: شاخص تحریک; APC; antigen-presenting cells; APL; altered peptide ligands; CFA; complete Freund's adjuvant; CFSE; 5-(and 6-) carboxyfluorescein diacetate, succinimidyl ester; CNS; central nervous system; cpm; counts per minute; DC; dendritic cells; DLN; draining lymph
Characterization of human memory CD4+ T-cell responses to the dog allergen Can f 4
Keywords: شاخص تحریک; Memory T cells; TH1/TH2; T-cell epitope; HLA class II; Can f 4; lipocalin allergen; peptide; allergy; immunotherapy; APC; Antigen-presenting cell; EC50; Half-maximal effective concentration; IC50; Half-maximal inhibitory concentration; PIT; Peptide-based
Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction
Keywords: شاخص تحریک; PPD; p-phenylenediamine; PTD; p-toluylenediamine; ME-PPD; 2-methoxymethyl-p-phenylenediamine; LLNA; local lymph node assay; QRA; quantitative risk assessment; SCCS; Scientific Committee on Consumer Safety; HE-PPD; hydroxyethyl-PPD; WoE; weight-of-evidence
Cellular immunogenicity of a multi-epitope peptide vaccine candidate based on hepatitis C virus NS5A, NS4B and core proteins in HHD-2 mice
Keywords: شاخص تحریک; ALT; alanine aminotransferase; DMSO; dimethyl sulfoxide; ELISPOT; enzyme-linked immunospot; HCV; hepatitis C virus; IFA; incomplete Freund's adjuvant; CFA; complete Freund's adjuvant; IFN-α; interferon-α; IFN-γ; interferon-γ; OD; optical density; LDH;
Evaluation of the safety of ancient strains of wheat in coeliac disease reveals heterogeneous small intestinal T cell responses suggestive of coeliac toxicity
Keywords: شاخص تحریک; Coeliac disease; Ancient strains of wheat; Small intestinal gluten-sensitive T-cell lines; Proliferation assays; Heterogenous T-cell responses; CD; coeliac disease; GFD; gluten-free diet; TCL; T-cell line; tTG; tissue transglutaminase; Tmp_AA; Triticum mo
HLA-DR specific monoclonal antibodies block lymphoproliferative response to measles vaccine in vitro: A pilot study
Keywords: شاخص تحریک; MVV; measles virus vaccine; LPA; lymphoproliferation assays; MoAb; monoclonal antibodies; SI; stimulation index; MMR; measles-mumps-rubella; PBMC; peripheral blood mononuclear cells; PFU; plaque forming units; CTL; cytotoxic T lymphocytes; Cell-mediat
Quantitative risk assessment for skin sensitisation: Consideration of a simplified approach for hair dye ingredients
Keywords: شاخص تحریک; AEL; acceptable exposure level; AOO; acetone olive oil; CEL; consumer exposure level; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EC3; effective concentration of the test substance required to produce a three-fold increase in the stimulation index co
Vaccination with Leishmania histone H1-pulsed dendritic cells confers protection in murine visceral leishmaniasis
Keywords: شاخص تحریک; Ab; antibody; mAb; monoclonal antibody; FACS; fluorescence acquisition and cell sorting; SI; stimulation index; Murine visceral leishmaniasis; Histone H1; DCs-based vaccine; CpG ODNs; IFNγ; IL-10; IL-12;
Human leukocyte antigen associations with humoral and cellular immunity following a second dose of measles-containing vaccine: Persistence, dampening, and extinction of associations found after a first dose
Keywords: شاخص تحریک; 3H; tritiated hydrogen; anti-HBs; hepatitis B surface antigen antibody; Ci; Curie; CPM; counts per minute; EIA; enzyme immunoassay; HLA; human leukocyte antigen; IgG; immunoglobulin G; IQR; interquartile range; IU; international units; mL; milliliters; MM
ImMucin: A novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors
Keywords: شاخص تحریک; CTL; cytotoxic T lymphocytes; DC; dendritic cells; mAb; monoclonal antibody; SI; stimulation index; SP; signal peptide; TAA; tumor-associated antigen; TRA; tandem repeat array; VCs; vaccine candidates; MUC1; Cancer vaccine; MHC class I; MHC class II; Sign
Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4+ T cells against the swine-origin H1N1 influenza virus
Keywords: شاخص تحریک; S-OIV; swine-origin influenza A virus; TIV; seasonal trivalent vaccine; DCs; dendritic cells; iTEM; individualized T cell epitope measure; HA; hemagglutinin; SI; stimulation index; Influenza; Pandemic; H1N1; Informatics; Human; T cells; Cross-reactive;
Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis
Keywords: شاخص تحریک; Human; T cells; drug hypersensitivity; drug metabolism; cystic fibrosis; APC; Antigen-presenting cell; cpm; Counts per minute; DRESS; Drug rash with eosinophilia and systemic symptoms; SI; Stimulation index; SMX-NO; Nitroso sulfamethoxazole; UK; United Ki
Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis
Keywords: شاخص تحریک; Ab; antibody; mAb; monoclonal antibody; FACS; fluorescence acquisition & cell sorting; SI; stimulation index; PBMC; peripheral blood mononuclear cells; Murine visceral leishmaniasis; DCs-based vaccine; CpG ODNs; KMP-11; IFNγ; IL-10; IL-12; IL-17; TGF-β;
Ara h 2 peptides containing dominant CD4+ T-cell epitopes: Candidates for a peanut allergy therapeutic
Keywords: شاخص تحریک; Peanut allergy; Ara h 2; T-cell epitope; peptide; immunotherapy; aa; Amino acid; CFSE; 5,6-Carboxyfluorescein diacetate succinimidylester; CPE; Crude peanut extract; cpm; Counts per minute; EBV-B cells; EBV-transformed B cells; HLA-II; HLA class II; nAra
A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS
Keywords: شاخص تحریک; Recombinant allergen; cat allergy; Fel d 1; peptide; hypoallergenic vaccine; immunotherapy; HBV; Hepatitis B virus; HRP; Horseradish peroxidase; RBL; Rat basophil leukemia; SI; Stimulation index; SIT; Allergen-specific immunotherapy;
Reshaping the Bet v 1 fold modulates TH polarization
Keywords: شاخص تحریک; Protein remodeling; tree pollen allergens; Bet v 1 family; TH-cell polarization; IgE reactivity; allergenicity; antigen uptake; lysosomal degradation; ALUM; Aluminum hydroxide; ANS; 8-Anilino-1-naphtalene sulfonic acid; APC; Allophycocyanin; BMDC; Bone ma
T-cell responses at baseline and during therapy with peginterferon-α and ribavirin are not associated with outcome in chronic hepatitis C infected patients
Keywords: شاخص تحریک; aa; amino acid; CD; code of differentiation; DMSO; dimethylsulphoxide; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence activated cell sorting; HCV; hepatitis C virus; HIV; human immunodeficiency virus; IFN-γ; interferon-γ; IL-2; interleukin
Considerations for optimization and validation of an in vitro PBMC derived T cell assay for immunogenicity prediction of biotherapeutics
Keywords: شاخص تحریک; ATA or ADA; anti-therapeutic/drug antibody; ELISPOT; enzyme-linked immunosorbent spot; FPX; fusion protein; PBMC; peripheral blood mono-nuclear cells; SFC; spot forming cells; SI; stimulation index; PBMC; ELISPOT; Immunogenicity prediction; Memory T cells
Naturally processed T cell-activating peptides of the major birch pollen allergen
Keywords: شاخص تحریک; Birch pollen allergy; Bet v 1; antigen processing; antigen presentation; dendritic cells; T cells; T-cell epitopes; aa; Amino acid; APC; Antigen-presenting cell; cpm; Counts per minute; DC; Dendritic cell; SI; Stimulation index; TCC; T-cell clone; TCL; T-
Autoimmune spread to myelin is associated with experimental autoimmune encephalomyelitis induced by a neuronal protein, β-Synuclein
Keywords: شاخص تحریک; EAE; experimental autoimmune encephalomyelitis; MS; multiple sclerosis; βSync; beta synuclein; IPTG; isopropyl-{beta}-d-thiogalactopyranoside; SI; stimulation index; NFL; neurofilament; LNC; lymph node cells; CP; cyclophosphamide; TMB; tetramethylbenzidi
Exercise enhances vaccine-induced antigen-specific T cell responses
Keywords: شاخص تحریک; AL; consumed food ad libitum; ALÂ +Â EX; consumed food ad libitum plus given access to voluntary running wheels; APC; antigen-presenting cell; Con A; concanavalin A; DTH; delayed type hypersensitivity; HSV-1; herpes simplex virus-1; IL; interleukin; KLH;
Expansion of hepatitis C-specific CD4+CD25+ regulatory T cells after viral clearance: A mechanism to limit collateral damage?
Keywords: شاخص تحریک; Hepatitis C infection; regulatory T cells; autoimmunity; viral clearance; viral persistence; HCV; Hepatitis C virus; SI; Stimulation index; TCR; T-cell receptor; Treg; CD4+CD25+ regulatory T; UK; United Kingdom;
Therapeutic Vaccination of Chronic Hepatitis C Nonresponder Patients With the Peptide Vaccine IC41
Keywords: شاخص تحریک; CTLs; cytotoxic T lymphocytes; IFN; interferon; PBMC; peripheral blood mononuclear cells; SI; stimulation index; Tc1; cytotoxic T cell; Th; T helper cell;
Impairment of T-regulatory cells in cord blood of atopic mothers
Keywords: شاخص تحریک; Adaptive; cord blood; cytokines; innate; IL; regulatory T cells; TH17 cells; Toll-like receptor; CBMC; Cord blood mononuclear cell; cpm; Counts per minute; CT; Threshold cycle; CTLA4; Cytotoxic T-lymphocyte-associated protein 4; D+L; Dermatophagoides pt
HCV-Specific T-Cell Response in Relation to Viral Kinetics and Treatment Outcome (DITTO-HCV Project)
Keywords: شاخص تحریک; CTL; cytotoxic T lymphocytes; IDV; individualized treatment regimen; IFN; interferon; PBMCs; peripheral blood mononuclear cells; RVR; rapid viral responder; SI; stimulation index; STD; control group; SVR; sustained virologic response;
Identification of minimal CD8+ and CD4+ T cell epitopes in the Plasmodium yoelii hepatocyte erythrocyte protein 17Â kDa
Keywords: شاخص تحریک; ID; intradermaly; ICS; intracellular cytokine staining; IFA; incomplete freund's adjuvant; IFAT; indirect fluorescent antibody test; IM; intramuscularly; LPA; lymphoproliferation assay; mAb; monoclonal antibody; NYLS3; Navy yoelii liver stage 3; P. falcip
The presence of donor-reactive CD4 T cells in early-phase liver-induced tolerance in rats: Analysis using donor passenger leukocytes from the recipient
Keywords: شاخص تحریک; ALT; alanine aminotransferase; CTL; cytotoxic T lymphocyte; LEW; Lewis; PLs; passenger leukocytes; PVG; Piebald virol Glaxo; SI; stimulation index; WF; Wistar Furth; Rat liver transplantation; Donor passenger leukocytes; CD4 T-cell response; Tolerance ind
A rodent model for allergic dermatitis induced by flea antigens
Keywords: شاخص تحریک; RT-PCR; reverse transcriptase PCR; HPRT; hypoxanthine phosphoribosyl transferase; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium; PMS; phenazine methosulfate; PBST; phosphate buffer saline plus Tween 20; BSA;
Flow cytometric characterisation of antigen presenting dendritic cells after in vitro exposure to diesel exhaust particles
Keywords: شاخص تحریک; DEP; diesel exhaust particles; Mo-DC; monocyte-derived dendritic cells; LPS; lipopolysaccharide; SI; stimulation index;
Frequency of beryllium-specific, TH1-type cytokine-expressing CD4+ T cells in patients with beryllium-induced disease
Keywords: شاخص تحریک; Human; lung; CD4-positive T lymphocyte; beryllium; autoimmunity; BAL; Bronchoalveolar lavage; BeLPT; Beryllium lymphocyte proliferation test; BeS; Beryllium-sensitized; CBD; Chronic beryllium disease; ROC; Receiver operator characteristic; SFU; Spot-formi
Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A
Keywords: شاخص تحریک; Astilbin; immunosuppressant; contact hypersensitivity; picryl chloride; IL-10; TNF-α; IFN-γ; DTH; Delayed-type hypersensitivity; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SI; Stimulation index; SOCS; Suppressor of cytokine signa
Infant home endotoxin is associated with reduced allergen-stimulated lymphocyte proliferation and IL-13 production in childhood
Keywords: شاخص تحریک; Endotoxin; lymphocyte proliferation; cytokine; childhood; allergy; EU; Endotoxin units; OR; Odds ratio; SI; Stimulation index; TLR4; Toll-like receptor 4;
The importance of standardisation of laboratory evaluations in HIV vaccine trials
Keywords: شاخص تحریک; Standardisation; Assay; Immunological response; Vaccine; APC; antigen presenting cell; AVIP; AIDS Vaccine Integrated Project; CAF; CD8 anti-viral factor; CASA; CD8 anti-HIV suppressor activity; CBA; cytometric bead array; CFSE; carboxyfluorescein diacetat
Leishmania infantum: soluble proteins released by the parasite exert differential effects on host immune response
Keywords: شاخص تحریک; cDNA; complementary deoxyribonucleic acid; cpm; counts per minute; Ag; crude Leishmania antigen; DNA; deoxyribonucleic acid; ELISA; enzyme-linked immunosorbent assay; ECM; extracellular matrix; FCS; foetal calf serum; HPRT; hypoxanthine guanine phosphorib
Antibodies and PMBC from EIAV infected carrier horses recognize gp45 and p26 synthetic peptides
Keywords: شاخص تحریک; aa; amino acids; AGID; agar gel immunodiffusion; BrdU; Bromo d-Uridine; CTL; Cytotoxic T Lymphocyte; EIAV; equine infectious anemia virus; FCA; Freund's Complete Adjuvant; Fmoc; 9-fluorenylmethoxycarbonyl; gp45; glycoprotein 45; PBMC; peripheral blood mon
Effects of environmental stressors on lymphocyte proliferation in Florida manatees, Trichechus manatus latirostris
Keywords: شاخص تحریک; MML; Mote Marine Laboratory; FMRI; Florida Marine Research Institute; USGS; United States Geological Survey; SI; stimulation index; BrdU; bromodeoxyuridine; PbTx; Ptychodiscus brevis toxin; ANOVA; analysis of variance; Manatee; Lymphocyte proliferation; I