کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6068677 | 1587134 | 2015 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Allergy to Surgical Implants
ترجمه فارسی عنوان
آلرژی به ایمپلنت های جراحی
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کلمات کلیدی
WBCMMATLR4LPTOrthopedic implants - ایمپلنت ارتوپدیLymphocyte proliferation test - تست تکثیر لنفوسیتPatch testing - تست پچJoint replacements - جایگزین های مشترکstimulation index - شاخص تحریکMethacrylates - متاکریلاتMethyl methacrylate - متیل متاکریلاتNickel - نیکلPMMA - پلی (متیل متاکریلات) polymethyl methacrylate - پلی متیل متاکریلاتCobalt - کبالتwhite blood cell - گلبول سفید خونToll-like receptor 4 - گیرنده تله مانند 4
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Surgical implants have a wide array of therapeutic uses, most commonly in joint replacements, but also in repair of pes excavatum and spinal disorders, in cardiac devices (stents, patches, pacers, valves), in gynecological implants, and in dentistry. Many of the metals used are immunologically active, as are the methacrylates and epoxies used in conjunction with several of these devices. Allergic responses to surgical components can present atypically as failure of the device, with nonspecific symptoms of localized pain, swelling, warmth, loosening, instability, itching, or burning; localized rash is infrequent. Identification of the specific metal and cement components used in a particular implant can be difficult, but is crucial to guide testing and interpretation of results. Nickel, cobalt, and chromium remain the most common metals implicated in implant failure due to metal sensitization; methacrylate-based cements are also important contributors. This review will provide a guide on how to assess and interpret the clinical history, identify the components used in surgery, test for sensitization, and provide advice on possible solutions. Data on the pathways of metal-induced immune stimulation are included. In this setting, the allergist, the dermatologist, or both have the potential to significantly improve surgical outcomes and patient care.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 3, Issue 5, SeptemberâOctober 2015, Pages 683-695
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 3, Issue 5, SeptemberâOctober 2015, Pages 683-695
نویسندگان
Karin A. MD, MSPH,