Keywords: C-NAC; chitosan-N-acetylcysteine; HCjE; human conjunctival epithelial; TEER; Transepithelial electrical resistance; BAB; boric acid buffer; FITC; fluorescein-isothiocyanate; LDH; lactate dehydrogenase; DAPI; 4â²,6-Diamidin-2-phenylindole; PBS; phosphate
مقالات ISI (ترجمه نشده)
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Keywords: ALI; air-liquid interface; ARDS; acute respiratory distress syndrome; COPD; chronic obstructive pulmonary disease; DCF; dichlorofluorescin; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; ELISA; enzyme-linked immuno assay; FBS; foetal bovine serum; H2O2
Keywords: POM; pomegranate; ALD; alcoholic liver disease; TJ; tight junction; AJ; adherent junction; CYP2E1; ethanol-inducible cytochrome P450-2E1; iNOS; inducible nitric oxide synthase; nitroxidative stress; oxidative and nitrative stress; KI mice; knock-in mice;
Keywords: STY; Salmonella Typhi; STM; Salmonella Typhimurium; M cells; Microfold cells; CFU; colony forming units; LB; Luria Burtoni broth; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered saline; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic
Keywords: Epithelial Barrier; Serine Proteases; Gut Microbiota; Inflammatory Bowel Diseases; ABx; antibiotics; AEBSF; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; cecal-sup; cecal-supernatants; ctr; control; DSS; dextran sulfate sodium; GF; germ-free; I
Keywords: Enniatin A; Enniatin A1; Enniatin B; Enniatin B1; Beauvericin; Emerging; IPEC-J2; Apoptosis; Necrosis; Flow cytometry; Annexin-V-FITC; Annexin-V-fluorescein isothiocyanate; BEA; beauvericin; BrdU; 5-bromo-2-deoxyuridine; Caco-2; human colon adenocarcinoma
Keywords: Corneal epithelial barrier function; Cytotoxicity; Heavy metals; TEER; Human eyes; ZO-1 proteins;
Keywords: A; area of Transwell insert; AIC; air-interface culture; ANOVA; analysis of variance; ATP; adenosine triphosphate; BCA; bicinchoninic assay; CF; cystic fibrosis; CPFX; ciprofloxacin in solution; dM/dt; steady-state linear slope of the transport vs. time p
Keywords: Mucus; Cell-based models; Mucosal model; Epithelium model; Permeation; Absorption; 2D; two-dimension; 3D; three-dimension; ALI; air-liquid culture; BCS; biopharmaceutics classification system; CV; cervicovaginal; CVM; cervicovaginal mucus; DDS; drug deliv
Keywords: l-Arginine; Heat stress; Inducible nitric oxide synthase; Nitric oxide; Intestinal barrier integrity; E-cadherin; AJ; adherens junctions; ANOVA; analysis of variance; Caco-2; epithelial colorectal adenocarcinoma; DMEM; Dulbecco modified Eagle minimum esse
Keywords: BA; bioavailability; C7; sodium enanthate; C9; sodium pelargonate; C10; sodium caprate; C11:1; sodium undecylenate; C12; sodium laurate; C12E8; polyoxyethylene-8 lauryl ether; CCh; carbachol; ER; enhancement ratio; ÎISC; change in short circuit current;
Keywords: Polymers; Ocular drug delivery; Nanoparticles; Microparticles; Gels; Ocular bioavailability; ABC; ATP-binding cassette superfamily; ANDA; Abbreviated new drug application; AUC; Area-under-the-curve; BSA; Bovine serum albumin; DDS; Drug delivery system; EP
Keywords: AJ; adherent junctions; CFTR; cystic fibrosis conductance regulator; ECGF; endothelial cell growth factor; EMV; endothelial microvesicles; eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endothelial cells; PAEC; pulmonary artery endot
Keywords: CFU; colony forming units; EPS; extracellular polysaccharide; GIT; gastrointestinal tract; GM-CSF; granulocyte macrophage colony-stimulating factor; ETEC; enterotoxigenic E. coli; FOS; fructo-oligosaccharide; GOS; galacto-oligosaccharide; HSP; heat shock
Keywords: AA; amino acids; ANF; anti-nutritional factors; ADFI; average daily feed intake; ADG; average daily gain; C. perfringens; Clostridium perfringens; DON; deoxynibalenon; E. coli; Escherichia coli; FCR; feed conversion ratio; FB-1; fumonisin B1; GIT; gastroi
Keywords: barrier function; endothelial permeability; endothelium; GC; glucocorticosteroid; HC; hydrocortisone; HLMVEC; human lung microvascular endothelial cell; IL; interleukin; LPS; lipopolysaccharide; MLC2; myosin light chain 2; PBS; phosphate-buffered saline;
Keywords: BBB; blood-brain barrier; CNS; central nervous system; hPSCs; human pluripotent stem cells; BMECs; brain microvascular endothelial cells; P-gp; P-glycoprotein; RA; retinoic acid; UM; unconditioned medium; EC; endothelial cell; ECÂ +Â RA medium; EC mediu
Keywords: Corneal endothelium; Barrier function; Actomyosin; Rho GTPase; RhoA; Rho kinase; Thrombin; HCEC; human corneal endothelial cell; GTPase; guanosine triphosphatase; GTP; guanosine triphosphate; ROCK; Rho kinase; MRCK; myotonic dystrophy kinase-related Cdc42
Keywords: AGE; Advanced Glycation End Products; ddPCR; droplet digital PCR; DHA; docosahexaenoic acid; EC; endothelial cells; eNOS; endothelial Nitric Oxide Synthase; GLUT; glucose transporter; HAoEC; Human Aortic Endothelial Cells; HDMEC; Human Dermal Microendothe
Keywords: BCA; bicinchoninic acid; CFSE; carboxyfluorescein diacetate succinimidyl ester; DAPI; (4â²,6-diamidino-2-phenylindole, dihydrochloride); DMEM; Dulbecco's Modified Eagle's Medium; DPBS; Dulbecco's phosphate-buffered saline; EDC; N-(3-dimethylaminopropyl)-
Keywords: BBB; Blood-brain barrier; DMSO; dimethyl sulfoxide; DPN; 2,3-bis(4-hydroxy-phenyl)-propionitrile; ERK1/2; extracellular signal-regulated kinase1/2; E2; 17β-estradiol 3-benzoate; ERs; estrogen receptors; HIF-1α; hypoxia-inducible factor 1α; FITC; fluo
Keywords: BLG; (bovine) beta-lactoglobulin; CBLG; cationic beta-lactoglobulins. These include C-EDA and C-P600 in this study; EDA; ethylenediamine; PEI; (branched) polyethyleneimine; EDC; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; C-EDA; ethylene-derived cation
Keywords: TJs; tight junctions; ZO; zonula occludens; LDH; lactate dehydrogenase; TEER; transepithelial electrical resistance; MALT; mucosa-associated lymphoid tissue; EL; extracellular loop, mmu - milli-mass unit; Actinidin; Cysteine protease; Intestinal permeab
Keywords: 4-MP; 4-methylpyrazole; ADH; alcohol dehydrogenase; ALD; alcoholic liver disease; BHMT; betaine-homocysteine methyltransferase; CYP 2E1; cytochrome P 450 2E1; DMG; dimethylglycine; SAH; S-adenosylhomocysteine; TEER; transepithelial electric resistance; TJ
Keywords: AF660; Alexa Fluor 660; BBB; blood brain barrier; CNS; central nervous system; DLS; dynamic light scattering; ECM; endothelial cell medium; Enf; enfuvirtide; Epf; epifluorescence; FI; fluorescence intensity; FD40; FITC-Dextran 40; FITC; fluoresceinamine;
Keywords: Hyperglycemia & methylglyoxal; Carbonyl stress & endothelial GSH; Occludin glycation & brain endothelial barrier function; Diabetic brain microvascular dysfunction; Streptozotocin & diabetes; N-acetylcysteine & endothelial barrier function; AGEs; advanced
Keywords: NPs; nanoparticles; CME; clathrin-mediated endocytosis; BBB; blood-brain barrier; FBS; fetal bovine serum; TEER; transepithelial electrical resistance; Papp; apparent permeability coefficient; ALP; alkaline phosphatase; LacCer; lactosylceramide; PBS; ph
Keywords: BCS; Biopharmaceutics Classification System; ConA; concanavalin A; GI; gastrointestinal; IBD; inflammatory bowel disease; IBS; irritable bowel syndrome; MEMS; microelectromechanical systems; MIMIC; micromolding in capillaries; MIPs; molecularly imprinted
Keywords: ABC; ATP binding cassette; AD; Alzheimer's disease; ApoE; Apolipoprotein E; AQP; Aquaporin; Aβ; Amyloid-β; AβPP; Aβ precursor protein; BACE-1; β-site AβPP cleaving enzyme 1; BBB; Blood-brain barrier; CBF; Cerebral blood flow; CSF; Cerebrospinal fl
Keywords: CA; citric acid; Cit; citrate; DOC; sodium deoxycholate; EDTA; ethylenediaminetetraacetic acid; ISE; ion selective electrode; KH; Krebs-Henseleit; LCC; lauroyl carnitine chloride; sCT; salmon calcitonin; TDC; taurodeoxycholate; TEER; transepithelial ele
Keywords: DDS; drug delivery system; PDI; polydispersity index; TEM; transmission electron microscopy; FaSSGF; fasted-state simulated gastric fluids; FeSSGF; fed-state simulated gastric fluids; FaSSIF; fasted-state simulated intestinal fluids; FeSSIF; fed-state sim
Keywords: Hg(II); divalent inorganic mercury; CH3Hg; methylmercury; ROS; reactive oxygen species; RNS; reactive nitrogen species; DMEM; Dulbecco's modified eagle medium; DMEMc; supplemented DMEM; MEM; minimum essential medium; DCF; dichlorofluorescein; SSA; 5-sulfo
Keywords: AJC; apical junction complex; MLC; myosin light chain; IBD; inflammatory bowel diseases; DSS; dextran sulfate sodium; TEER; trans-epithelial electric resistance; AJ; adherens junction; TJ; tight junction; NMIIA; non-muscle myosin II A; Apical junctional c
The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers
Keywords: AD; Decoction of processed aconite root; ALD; Decoction of processed aconite root and honey-processed liquorice; AP; Apical; BCRP; Breast cancer resistance protein; BL; Basolateral; DDAs; Diester-diterpenoid alkaloids; EIC; Extracted ion chromatogram; ER;
Development of a label-free FcRn-mediated transcytosis assay for in vitro characterization of FcRn interactions with therapeutic antibodies and Fc-fusion proteins
Keywords: mAb; monoclonal antibody; IgG; immunoglobulin G; FcRn; neonatal Fc receptor; MHC; major histocompatibility complex; B2M; β2 microglobulin; TEER; trans-epithelial electrical resistance; MDCK; Madin-Darby Canine Kidney; FACS; florescence-activated cell sor
Blood-brain barrier permeability and neuroprotective effects of three main alkaloids from the fruits of Euodia rutaecarpa with MDCK-pHaMDR cell monolayer and PC12 cell line
Keywords: EF; Euodiae Fructus; EDM; evodiamine; RCP; rutaecarpine; DEDM; dehydroevodiamine; Papp; apparent permeability coefficients; P-gp; P-glycoprotein; MPP+; 1-methyl-4-phenylpyridinium ion; H2O2; hydrogen peroxide; TCM; traditional Chinese medicine; BBB; blood
In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein
Keywords: BBB; blood-brain barrier; BCRP; Breast Cancer Resistance Protein; BSA; bovine serum albumin; DAD; diode-array detection; DBH; dopamine β-hydroxylase; DDIs; drug-drug interactions; DMSO; dimethyl sulfoxide; EMA; European Medicines Agency; HBSS; Hanks bala
Monocultures of primary porcine brain capillary endothelial cells: Still a functional in vitro model for the blood-brain-barrier
Keywords: Blood brain barrier; In vitro models; Drug delivery; Nanoparticles; Enzyme replacement therapy; Impedance spectroscopy; ABC; ATP binding casette; ASA; Arylsulfatase A; ATP; Adenosintriphosphate; Apo-E; Apolipoprotein E; AuNP; Gold nanoparticle; PBCA-NP; p
Changes in antioxidant activity of Alcalase-hydrolyzed soybean hydrolysate under simulated gastrointestinal digestion and transepithelial transport
Keywords: SPH; soybean protein hydrolysate; SPH-G; gastric-digested soybean protein hydrolysate; SPH-GI; gastrointestinal-digested soybean protein hydrolysate; ROS; reactive oxygen species; GI; gastrointestinal; SF; skim fraction; DPPH; 1,1-diphenyl-2-picrylhydrazy
Behavior of three hypocholesterolemic peptides from soy protein in an intestinal model based on differentiated Caco-2 cell
Keywords: Hypocholesterolemic peptides; Caco-2 cells; DPP-IV; HMGCoAR; In silico docking; Intestinal absorption; LC-MRM; Mass spectrometry; Soy protein; ACN; acetonitrile; AP; apical; BL; basolateral; CV; coefficient of variance; DMEM; Dulbecco's Modified Eagle M
Temperature-treated gluten proteins in Gluten-Friendly⢠bread increase mucus production and gut-barrier function in human intestinal goblet cells
Keywords: Gluten-Friendly bread; HT29 cell line; Intestinal permeability; Mucus production; Trans-epithelial electrical resistance; CD; coeliac disease; CB; control bread; GFB; Gluten-Friendly⢠bread; GFD; Gluten-free diet; PAS; Periodic Acid-Schiff; AB; Alcian B
Protective effect of bioaccessible fractions of citrus fruit pulps against H2O2-induced oxidative stress in Caco-2 cells
Keywords: N; Navel orange; CC; Cara Cara orange; M; mandarin freshly harvested; M12; mandarin refrigerated stored; BF; bioaccesible fractions; ROS; reactive oxygen species; t-BuOOH; tert-Butyl hydroperoxide; ABTSâ¢+;  2,2â²-azino-bis [3 ethylbenzothiazoline-6-su
Butyrate ameliorated-NLRC3 protects the intestinal barrier in a GPR43-dependent manner
Keywords: T2DM; type 2 diabetes; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NOD; nucleotide-binding oligomerization domain; NLRs; nucleotide-binding oligomerization domain (NOD)-like receptors; MAMPs; microbe-associated molecular patterns; NLRP
Integration of Sensors in Gastrointestinal Organoid Culture for Biological Analysis
Keywords: GI Organoids; Bioengineered Sensor; Organoid Microenvironment; FITC; fluorescein isothiocyanate; FITC-Dex; fluorescein isothiocyanate-dextran; GI; gastrointestinal; HIO; human intestinal organoid; NO; nitric oxide; RT-PCR; reverse-transcription polymerase
Assessing the impact of benzo[a]pyrene with the in vitro fish gut model: An integrated approach for eco-genotoxicological studies
Keywords: NF; naphthoflavone; 3Rs; Replace, Reduce, Refine; ADME; Adsorption, Distribution, Metabolism and Excretion; AHR; Aryl hydrocarbon receptor; AOP; Adverse Outcome Pathway; APH; Acid phosphatase; B[a]P; Benzo[a]pyrene; DMSO; Dimethyl sulfoxide; ECVAM; Europe
Influence of PLA-PEG nanoparticles manufacturing process on intestinal transporter PepT1 targeting and oxytocin transport
Keywords: Polymeric nanoparticles; PepT1 transporter; Nanoprecipitation; Emulsion; Intestinal targeting; Oxytocin; ACN; acetonitrile; ATFA; trifluoroacetic acid; BSA; bovine serum albumin; DCM; dichloromethane; DMF; N,N-dimethylformamide; DL; drug load; DLS; dynami
Probiotics in IBD: Combining in vitro and in vivo models for selecting strains with both anti-inflammatory potential as well as a capacity to restore the gut epithelial barrier
Keywords: Probiotics; Inflammatory bowel disease; Colitis; Intestinal permeability; CD; Crohn's disease; PBMC; Peripheral blood mononuclear cells; TEER; Trans-epithelial Electrical Resistance; UC; ulcerative colitis; TNBS; Trinitrobenzene sulfonic acid; MRS; de Man
Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke
Keywords: 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;
Human Fetal-Derived Enterospheres Provide Insights on Intestinal Development and a Novel Model to Study Necrotizing Enterocolitis (NEC)
Keywords: Necrotizing Enterocolitis; Fetal Organoids; Enteroids; AD; adult duodenal; AEnS; adult-derived enterospheres; CLDN; claudin; ÎÎCT; relative threshold cycle; CXCL; chemokine (C-X-C motif) ligand; DMEM; Dulbecco's modified Eagle medium; EGF; epidermal gro
Labrasol® and Salts of Medium-Chain Fatty Acids Can Be Combined in Low Concentrations to Increase the Permeability of a Macromolecule Marker Across Isolated Rat Intestinal Mucosae
Keywords: permeation enhancer; macromolecular drug delivery; epithelial delivery/permeability; peptide delivery; oral drug delivery; BA; bioavailability; BCS; Biopharmaceutics Classification System; C10; sodium caprate; C11:1; sodium undecylenate; C12; sodium laura