دانلود مقالات ISI درباره Wes + ترجمه فارسی

اثربخشی نسبی ژنومی نسل بعد برای تشخیص بیماری: طراحی یک کارآزمایی کنترل شده تصادفی در بیماران مبتلا به سندرم های سرطان کولورکتال / پولیپوز

Comparative effectiveness of next generation genomic sequencing for disease diagnosis: Design of a randomized controlled trial in patients with colorectal cancer/polyposis syndromes

Keywords: CER; comparative effectiveness research; PCOR; patient-centered outcomes research; WES; whole exome sequencing; IFs; incidental findings; CRCP; colorectal cancer and polyposis syndromes; MMR; mismatch repair; RCT; randomized controlled trial; PRO; patient

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

تحقیق مقاله تحلیل نمونه گیری فردی در تشخیص و مدیریت نارسایی کبد کودکان از علل نامشخص

Research ArticleIndividual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology

Keywords: WES; whole exome sequencing; PALF; paediatric acute liver failure; US; United States; MDS; mitochondrial DNA depletion syndrome; WD; Wilson disease; EASL; European Association for the Study of the Liver; CT; computerized tomography; MRI; magnetic resonanc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

کاربرد بالینی آزمایش ژنتیک در صرع مقاوم به داروهای کودکان: یک مطالعه آزمایشی

Clinical utility of genetic testing in pediatric drug-resistant epilepsy: A pilot study

Keywords: AR; autosomal recessive; PDRE; pediatric drug-resistant epilepsy; DRE; drug-resistant epilepsy; EE; epileptic encephalopathy; WES; whole exome sequencing; VUS; variant of unknown significance; AED; antiepileptic drug; IGE; idiopathic generalized epilepsy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

نمونه های خالی از نقطه خالی خشک شده نوزادان آرشیو شده می تواند برای تعیین دقیق ژنوم کامل و توالی بعدی نسل آینده مورد استفاده قرار گیرد

Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing

Keywords: DBSS; dried blood spot samples; gDNA; genomic DNA; wgaDNA; whole-genome amplified DNA; DNSB; Danish Newborn Screening Biobank; NGS; next generation sequencing; WGS; whole-genome sequencing; WES; whole exome sequencing; SNV; single nucleotide variation; SN

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

پیشرفت و برجسته شدن در کمبود های اولیه ایمنی در سال 2017

Advances and highlights in primary immunodeficiencies in 2017

Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

TDRD6 is associated with oligoasthenoteratozoospermia by sequencing the patient from a consanguineous family

Keywords: OAT; oligoasthenoteratozoospermia; WES; whole-exome sequencing; ICSI; intracytoplasmic sperm injection; IVF; in vitro fertilization; ExAC; Exome Aggregation Consortium; gnomAD; genome Aggregation Database; dbSNP; Short Genetic Variations database; 1000G;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Utilization of Genomics and Functional Genomics to Inform Clinical Decisions in IR

Keywords: lncRNA; long noncoding RNA; LRT; locoregional therapy; miRNA; microRNA; RNA-Seq; RNA sequencing; WES; whole-exome sequencing; WGS; whole-genome sequencing;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Genetic contribution of SUN5 mutations to acephalic spermatozoa in Fujian China

Keywords: WES; whole-exome sequencing; ODF1; outer dense fiber 1; ExAC; Exome Aggregation Consortium; SNP; single nucleotide polymorphism; WB; western blot; IF; immunofluorescence; Acephalic spermatozoa; SUN5; Whole-exome sequencing; ODF1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Whole exome sequencing identifies a novel mutation (c.333 + 2T > C) of TNNI3K in a Chinese family with dilated cardiomyopathy and cardiac conduction disease

Keywords: DCM; Dilated Cardiomyopathy; SCD; Sudden cardiac death; CCD; Cardiac conduction disease; TNNI3K; TNNI3 Interacting Kinase; cTnI; cardiac tropnin I; ECG; 12-lead echocardiogram; WES; Whole exome sequencing; PCR; Polymerase chain reaction; LV; Left ventricu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Whole exome sequencing identifies a pathogenic mutation in WFS1 in two large Chinese families with autosomal dominant all-frequency hearing loss and prenatal counseling

Keywords: WFS1; All-frequency sensorineural hearing loss; Prenatal diagnosis; Autosomal dominant; WES;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

What do genetic studies tell us about the heritable basis of common epilepsy? Polygenic or complex epilepsy?

Keywords: Common epilepsy; Genetic architecture; Polygenic; GWAS; WES;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Research Techniques Made Simple: Genome-Wide Homozygosity/Autozygosity Mapping Is a Powerful Tool for Identifying Candidate Genes in Autosomal Recessive Genetic Diseases

Keywords: AR; autosomal recessive; EB; epidermolysis bullosa; GATK; Genome Analysis Toolkit; HM; homozygosity mapping; Mb; mega base pair; NGS; next-generation sequencing; ROH; region of homozygosity; SNP; single nucleotide polymorphism; WES; whole-exome sequencing

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Mutations in AIFM1 cause an X-linked childhood cerebellar ataxia partially responsive to riboflavin

Keywords: Cerebellar atrophy; Auditory neuropathy; Axonal neuropathy; Myoclonus; Riboflavin; WES; whole exome sequencing; OXPHOS; oxidative phosphorylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Nonsyndromic Retinitis Pigmentosa in the Ashkenazi Jewish Population

Keywords: AD; autosomal dominant; AJ; Ashkenazi Jewish; AR; autosomal recessive; BCVA; best-corrected visual acuity; BSP; bone spicule; EOG; electro-oculography; ERG; electroretinography; FA; fluorescein angiography; FAF; fundus autofluorescence; FC; finger countin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

SPG11 mutations cause widespread white matter and basal ganglia abnormalities, but restricted cortical damage

Keywords: ACE-R; Addenbrooke's Cognitive Examination Revised; ALS; amyotrophic lateral sclerosis; CA; cord area; CE; cord eccentricity; CMAP; compound muscle action potential; CST; corticospinal tract; DTI; diffusion tensor imaging; FA; fractional anisotropy; GM; g

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Cardiac Genetic Predisposition in Sudden Infant Death Syndrome

Keywords: genetic heart diseases; molecular autopsy; sudden infant death syndrome; whole exome sequencing; GHD; genetic heart disease; gnomAD; Genome Aggregation Database; LQTS; long QT syndrome; MAF; minor allele frequency; NSV; nonsynonymous variant; PCA; princip

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Mutational Intratumor Heterogeneity is a Complex and Early Event in the Development of Adult T-cell Leukemia/Lymphoma

Keywords: ATL; Adult T-cell Leukemia/Lymphoma; HTLV-1; Human T-cell Leukemia Virus Type-1; PVL; Proviral Load; NGS; Next Generation Sequencing Technology; WES; Whole Exome Sequencing; SNV; Single Nucleotide Variation; CNA; Copy Number Alteration; VAF; Variant Allel

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Instantaneous direct voltage and frequency control in DC grid tied DFIG based wind energy system

Keywords: DC-DFIG; Instantaneous direct voltage and frequency control; WES; RSC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane

Keywords: AMD; age-related macular degeneration; ARMS2; Age-Related Maculopathy Susceptibility 2; ANNOVAR; Annotate Variation; CADD; Combined Annotation Dependent Depletion; CFH; complement factor H; CFI; complement factor I; CMC; Combined Multivariate and Collaps

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Review of the phenotype of early-onset generalised progressive dystonia due to mutations in KMT2B

Keywords: KTM2B; Dystonia; Microdeletions; Genetic and inherited disorders; CNV; Copy number variants; GPI-DBS; Globus pallidus interna-deep brain stimulation; ID; Intellectual disability; MLPA; Multiplex ligation-dependent probe amplification; MRI; Magnetic resona

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Two novel homozygous missense mutations identified in the BSND gene in Moroccan patients with Bartter's syndrome

Keywords: Deafness; BSND; Bartter syndrome type IV; WES; Moroccan family;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

A novel mutation in HAUS7 results in severe oligozoospermia in two brothers

Keywords: SO; severe oligozoospermia; WES; whole-exome sequencing; IVF; in vitro fertilization; ICSI; intracytoplasmic sperm injection; NOA; non-obstructive azoospermia; FSH; follicle-stimulating hormone; LH; luteinizing hormone; T; testosterone; PRL; prolactin; E2

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Whole exome sequencing identifies a novel 5 Mb deletion at 14q12 region in a patient with global developmental delay, microcephaly and seizures

Keywords: RTT; Rett syndrome; MECP2; Methyl-CpG-Binding Protein 2; CDKL5; Cyclin Dependent Kinase Like 5; FOXG1; Forkhead Box G1; OMIM; Online Mendelian Inheritance in Man; PRKD1; Protein Kinase D1; NOVA1; Neurooncologic Ventral Antigen 1; c14orf23; Chromosome 14 O

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Deficiency in GnRH receptor trafficking due to a novel homozygous mutation causes idiopathic hypogonadotropic hypogonadism in three prepubertal siblings

Keywords: CDGP; constitutional delay of growth and puberty; CHO; Chinese hamster ovary; E2; estradiol; ER; endoplasmic reticulum; FSH; follicle-stimulating hormone; GnRH; gonadotropin-releasing hormone; HEK; human embryonic kidney; H-P-G axis; hypothalamic-pituit

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Novel founder intronic variant in SLC39A14 in two families causing Manganism and potential treatment strategies

Keywords: Congenital manganism; SLC39A14; Manganese toxicity; BID; twice daily; CaNa2EDTA; edetate calcium disodium; CBC; complete blood count; cDNA; complementary DNA; dCT; delta cycle threshold; ddCT; double delta cycle threshold; DMSA; dimercaptosuccinic acid; M

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function

Keywords: ALS; TBK1; FTD; WES; Familial ALS;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema

Keywords: Hereditary angioedema; angiopoietin-1; gene; mutation; multimers; tunica interna endothelial cell kinase 2 receptor; ANGPT1; Angiopoietin-1; ANGPT2; Angiopoietin-2; C1-INH; C1 inhibitor; C1-INH-HAE; Hereditary angioedema caused by C1 inhibitor deficiency;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Subclonal Evolution of Cancer-Related Gene Mutations in p53 Immunopositive Patches in Human Skin

Keywords: AK; actinic keratosis; BD; Bowen's disease; COSMIC; Catalogue of Somatic Mutations in Cancer; cSCC; cutaneous squamous cell carcinoma; PIP; p53 immunopositive patch; VAF; variant allele frequency; WES; whole exome sequencing;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Pediatric-onset Evans syndrome: Heterogeneous presentation and high frequency of monogenic disorders including LRBA and CTLA4 mutations

Keywords: Autoimmune cytopenias; Immune checkpoint deficiencies; Extensive genetic screening; LRBA and CTLA-4 deficiencies; ES; Evans syndrome; AIHA; Autoimmune hemolytic anemia; ITP; Immune thrombocytopenia; ALPS; Autoimmune lymphoproliferative syndrome; CTLA-4; C

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer

Keywords: Colon Cancer; Familial Colorectal Cancer; Protein Translation; Mechanism; CRC; colorectal cancer; LOH; loss of heterozygosity; MAF; minor allele frequency; miRNA; microRNA; MMR; DNA mismatch repair; PBS; phosphate-buffered saline; PCR; polymerase chain re

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Gain-of-function KCNJ6 Mutation in a Severe Hyperkinetic Movement Disorder Phenotype

Keywords: GIRK; G protein-gated inwardly rectifying K+; KIR; inwardly rectifying potassium; SNc; substantia nigra compacta; WES; whole-exome sequencing; KCNJ6; weaver mouse; movement disorder; channelopathy; inward rectifier; KIR3;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Circulating tumor DNA - Current state of play and future perspectives

Keywords: BEAMing; beads, emultion, amplification, magnetics; bp; base pairs; cfDNA; circulating cell-free DNA; CNS; central nervous system; CRC; colorectal cancer; CSF; cerebrospinal fluid; CTC; circulating tumor Cell; ctDNA; circulating tumor DNA; ddPCR; droplet

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Whole Exome Sequencing allows the identification of two novel groups of Xeroderma pigmentosum in Tunisia, XP-D and XP-E: Impact on molecular diagnosis

Keywords: XP-E; XP-D; Founder mutations; WES; ROH;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The genotypic and phenotypic spectrum of MTO1 deficiency

Keywords: GDD; global developmental delay; HCM; hypertrophic cardiomyopathy; ID; intellectual disability; MRI; magnetic resonance imaging; MTO1; Mitochondrial tRNA Translation Optimization 1; OXPHOS; oxidative phosphorylation; Q-TOF; quadrupole time-of-flight; WES;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Combined immunodeficiency and atopy caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11)

Keywords: Caspase activation and recruitment domain family member 11; combined immunodeficiency; hypogammaglobulinemia; nuclear factor κB; cytokine secretion; T-cell repertoire; T-cell mitogen and antigen responses; autoimmunity; asthma; eczema and food allergies;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular genetics ‎characterization and homology modeling of the CHM gene mutation: A study on its association with choroideremia

Keywords: CHM; choroideremia; RPE; retinal pigment epithelium; REP-1; Rab escort protein-1; VA; visual acuity; OCT; optical coherence tomography; GGTase; geranylgeranyltransferase; ONL; outer nuclear layer; INL; inner nuclear layer; LCHADD; long-chain 3-hydroxyacyl

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

The Molecular Revolution in Cutaneous Biology: Era of Next-Generation Sequencing

Keywords: NGS; next-generation sequencing; WES; whole-exome sequencing;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Quantitation of CRM197 using imaged capillary isoelectric focusing with fluorescence detection and capillary Western

Keywords: Maurice; Imaged capillary IEF; Fluorescent detection; CRM197; Wes; Western blot;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Enzymatic testing sensitivity, variability and practical diagnostic algorithm for pyruvate dehydrogenase complex (PDC) deficiency

Keywords: PDC; pyruvate dehydrogenase complex; CI; confidence interval; TGP; targeted gene panel; TAT; turn-around-time; RR; reference range; WES; whole exome sequencing; WGS; whole genome sequencing; Biochemical testing; Sensitivity; Variability; Diagnostic algori

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Lethal neonatal case and review of primary short-chain enoyl-CoA hydratase (SCEH) deficiency associated with secondary lymphocyte pyruvate dehydrogenase complex (PDC) deficiency

Keywords: SCEH; short-chain enoyl-CoA hydratase; PDC; pyruvate dehydrogenase complex; KDC; α-ketoglutarate dehydrogenase complex; MDHB; 2-methyl-2,3-dihydroxybutyric acid; WES; whole exome sequencing; RR; reference range; DOL; day-of-life; Short-chain enoyl-CoA hy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

TMEM230 in Parkinson's disease

Keywords: Parkinson; TMEM230; GWAS; WES;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations

Keywords: Acute lymphoblastic leukemia; autoimmune disease; B-cell deficiency; common lymphoid progenitor; DNA binding; dysgammaglobulinemia; germline mutation; Ikaros; IKZF1; nuclear localization; BCP-ALL; B-cell precursor acute lymphoblastic leukemia; CLP; Common

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The case of an APDS patient: Defects in maturation and function and decreased in vitro anti-mycobacterial activity in the myeloid compartment

Keywords: APDS; activated PI3-kinase delta syndrome; WES; whole exome sequencing; BCG; Mycobacterium bovis bacillus Calmette Guèrin; PBMC; peripheral blood mononuclear cells; CFSE; carboxyfluorescein succinimidyl ester; IVIg; intravenous immunoglobulin; PB; periph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Succinyl-CoA synthetase (SUCLA2) deficiency in two siblings with impaired activity of other mitochondrial oxidative enzymes in skeletal muscle without mitochondrial DNA depletion

Keywords: SUCL; succinyl-CoA ligase; A-SCS; succinyl-CoA synthetase (ADP-forming); SM; skeletal muscle; PDC; pyruvate dehydrogenase complex; KDC; α-ketoglutarate dehydrogenase complex; PEPCK; phosphoenolpyruvate carboxykinase; ETC; electron transport chain; WES; w

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Association of a synonymous SCN1B variant affecting splicing efficiency with Benign Familial Infantile Epilepsy (BFIE)

Keywords: Benign Familial Infantile Epilepsy (BFIE); SCN1B; PRRT2; Splice variant; Minigene reporter assay; BIS; Benign Infantile Seizures; BFIC/BFIS; Benign Familial Infantile Convulsions/Seizures; BFIE; Benign Familial Infantile Epilepsy; WES; Whole Exome Sequenc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original articleExome sequencing in children of women with skewed X-inactivation identifies atypical cases and complex phenotypes

Keywords: Whole exome sequencing; WES; Skewed X-inactivation; ATRX; DMD; RPS6KA3; MECP2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Immune defects caused by mutations in the ubiquitin system

Keywords: Ubiquitin; nuclear factor κB; immunodeficiency; CVID; Common variable immunodeficiency; DUB; Deubiquitinating enzyme; EDA-ID; Ectodermal dysplasia with immunodeficiency; HECT; Homologous to EGAP C-terminus; HOIL-1; Heme-oxidase iron responsive element bi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Whole-Exome Sequencing Identifies Biallelic IDH3A Variants as a Cause of Retinitis Pigmentosa Accompanied by Pseudocoloboma

Keywords: arRP; autosomal recessive retinitis pigmentosa; CME; cystoid macular edema; IRD; inherited retinal disease; LCA; Leber congenital amaurosis; NAD; nicotinamide adenine dinucleotide; OCT; optical coherence tomography; RP; retinitis pigmentosa; RPE; retinal

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Neurology Individualized Medicine: When to Use Next-Generation Sequencing Panels

Keywords: ACMG; American College of Medical Genetics and Genomics; bp; base pair; CNV; copy number variation; HGMD; Human Gene Mutation Database; NGS; next-generation sequencing; OMIM; Online Mendelian Inheritance in Man; WES; whole-exome sequencing; WGS; whole-gen

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of two novel SH3PXD2B gene mutations in Frank-Ter Haar syndrome by exome sequencing: Case report and review of the literature

Keywords: PMSA; Protein multiple sequence alignments; FTHS; Frank-Ter Haar syndrome; WES; Whole Exome Sequencing; SH3; Src homology3; Frank-Ter Haar syndrome; SH3PXD2B; Whole exome sequencing;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه