دانلود مقالات ISI درباره Woe + ترجمه فارسی

حرکت از طریق میدان معدن چارچوب های خواندن: دیدگاه تفسیری

Navigating through the minefield of read-across frameworks: A commentary perspective

Keywords: ADME; Absorption, Distribution, Metabolism, Excretion; AOPs; adverse outcome pathways; AUC; Area under the Curve; AEs; assessment elements; AOs; assessment options; BMDL; benchmark dose lower bound; CAAT; Center for Alternatives to Animal Testing; Cefic-L

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

استنتاج عقلانی در ارزیابی ریسک تجمعی: نقشهای نمودارهای تصادفی هدایت شده

Causal inference in cumulative risk assessment: The roles of directed acyclic graphs

Keywords: CRA; cumulative risk assessment; DAG; directed acyclic graphs; CAFO; concentrated animal feeding operation; SES; socioeconomic status; MOA; mode of action; AOP; adverse outcome pathway; WOE; weight of evidence; NRC; National Research Council; USEPA; U.S.

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

ارزیابی سیستماتیک اثرات بالقوه تری کلروتیلن بر روی رشد قلب

A systematic evaluation of the potential effects of trichloroethylene exposure on cardiac development

Keywords: AOP; adverse outcome pathway; BMD; benchmark dose; BMDS; Benchmark Dose Software; BMDL; 95% lower confidence limit on the benchmark dose; BMR; benchmark response; CHD; congenital heart defects; CI; confidence interval; DCA; dichloroacetic acid; IRIS; Inte

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

تجزیه و تحلیل تطبیقی ​​دو روش شناخت وزن برای سنجش کیفیت رسوب یکپارچه

Comparative analysis of two weight-of-evidence methodologies for integrated sediment quality assessment

Keywords: Sediment; Dredged material; Toxicity; Elutriate; WOE; Integrated assessment;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

رویکرد وزن به شواهد در ارزیابی خطرات زیست توده سمی خاک اسید سولفات در رودخانه های رودخانه دریای بالتیک

Weight-of-evidence approach in assessment of ecotoxicological risks of acid sulphate soils in the Baltic Sea river estuaries

Keywords: Acid sulphate soil; Baltic Sea; Metal; Risk assessment; WoE;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

ارزیابی خطر مونومر باقی مانده مهاجرت از پلیمرهای اکریلیک و ایجاد درماتیت تماس با آلرژیک در هنگام دستکاری و استفاده معمول

Risk Assessment of residual monomer migrating from acrylic polymers and causing Allergic Contact Dermatitis during normal handling and use

Keywords: ACD; Allergic Contact Dermatitis; AEL; Acceptable Exposure Level; AF; assessment factor; AOO; acetone-olive oil; CEE; categorical exposure estimate; CEL; Consumer Exposure Level; CES; carboxylesterases; CSAF; Chemical-Specific Adjustment Factors; DDEF; Da

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

رویکردها و ملاحظات برای ارزیابی ایمنی مسکن برای مواد شیمیایی محیطی: خلاصه کارگاه

Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: A workshop summary

Keywords: 2,4-D; 2,4-dichlorophenoxyacetic acid; ACD; allergic contact dermatitis; ACSA; agricultural chemical safety assessment; AFC; antibody forming cell; CP; cyclophosphamide; CT; carbon tetrachloride; DART; developmental and reproductive toxicology; DIT; devel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

ارزیابی وزن مبتنی بر شواهد اثرات بویایی متیل متاکریلات در انسان و ایجاد یک سطح مواجهه شغلی

Hypothesis-based weight-of-evidence evaluation of methyl methacrylate olfactory effects in humans and derivation of an occupational exposure level

Keywords: Methyl methacrylate; Olfactory effects; Human relevance; Occupational levels; Physiologically based pharmacokinetic (PBPK) model; Dosimetric adjustment factors; 2-EH; 2-ethyl Hexanol; AA; acrylic acid; ACGIH; American Conference of Governmental Industrial

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats

Keywords: Propaquizafop; Carcinogenicity; Rodent hepatocarcinogenesis; PPARα; Liver; Peroxisome proliferators; Mode of action; Human relevance framework; Enzyme induction; Rats; ACO; Acyl-CoA oxidase; bw; body weight; BrdU; bromodeoxyuridine; CAT; catalase; CYP; c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Regulatory identification of BPA as an endocrine disruptor: Context and methodology

Keywords: Bisphenol A; Endocrine disruption; ED; SVHC; Substance of very high concern; REACh; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail (French Agency for Food, Environmental and Occupational Health & Sa

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Evidence-based adverse outcome pathway approach for the identification of BPA as en endocrine disruptor in relation to its effect on the estrous cycle

Keywords: Bisphenol A; Endocrine disruption; Female reproduction; Estrogen; ↑; increase; ↓; decrease; 2G; 2-generation study; 3G; 3-generation study; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail, (French Ag

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum

Keywords: Physiologically-based kinetic (PBK) modelling; Hazard and risk assessment; Weight-of-evidence (WoE); Threshold of toxicological concern (TTC); In vitro to in vivo extrapolation (IVIVE); Integrated approach for testing and assessment (IATA); Absorption; Di

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

AOPs in hazard characterization for human health

Keywords: Mode of action; Adverse outcome pathways; Key event; Key event relationship; Weight of evidence; Quantitation; AO; adverse outcome; AOP; adverse outcome pathway; AOP-KB; adverse outcome pathway knowledge base; B/H; Bradford-Hill; EAGMST; OECD Extended Adv

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook

Keywords: Omics; Transcriptomics; Weight-of-evidence; Registration, Evaluation, Authorisation, and Restriction (REACH); Plant protection products; Regulatory toxicology; Hazard assessment; Test method validation; Test method standardisation; AOP; Adverse outcome pa

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references

Keywords: Ac; Acylating agents; ACD; Allergic Contact Dermatitis; AOP; Adverse Outcome Pathway; ARE; Antioxidant Response Element; DC; dendritic cell; DMSO; dimethyl sulfoxide; DNCB; dinitrochlorobenzene; DPRA; Direct Peptide Reactivity Assay; ECVAM; European Centr

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Integrated in silico strategy for PBT assessment and prioritization under REACH

Keywords: REACH; Registration, Evaluation, Authorisation and Restriction of Chemicals; (Q)SAR; (quantitative) structure-activity relationship; ECHA; European Chemicals Agency; UBA; Umweltbundesamt; MCDM; multi-criteria decision making; WoE; weight of evidence; AD;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic™ Reconstructed Human Epidermis

Keywords: ECVAM; European Center for the Validation of Alternative Methods; ESAC; ECVAM Scientific Advisory Committee; EU; European Union; EU CLP; European Union System of Classification of Chemicals implemented in the EU Classification, Labelling and Packaging Reg

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Choice of population database for forensic DNA profile analysis

Keywords: WoE; Weight of Evidence; Q; Queried contributor; X; Alternate contributor that replaces Q in defence hypothesis; K; Contributor to the CSP whose reference profile is available; U; Unprofiled contributor to the CSP; Population database; DNA mixtures; Likel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction

Keywords: PPD; p-phenylenediamine; PTD; p-toluylenediamine; ME-PPD; 2-methoxymethyl-p-phenylenediamine; LLNA; local lymph node assay; QRA; quantitative risk assessment; SCCS; Scientific Committee on Consumer Safety; HE-PPD; hydroxyethyl-PPD; WoE; weight-of-evidence

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Optimizing the aquatic toxicity assessment under REACH through an integrated testing strategy (ITS)

Keywords: ACR; acute-to-chronic ratios; AF; assessment factor; BCF; bioconcentration factor; BOD5; 5-days biochemical oxygen demand; C&L; classification and labeling; CLP; classification, labeling and packaging; COD; chemical oxygen demand; CSA; chemical safety ass

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The OSIRIS Weight of Evidence approach: ITS for skin sensitisation

Keywords: Integrated Testing Strategy; ITS; REACH; Weight-of-Evidence; WoE; Bayesian inference;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Quantitative risk assessment for skin sensitisation: Consideration of a simplified approach for hair dye ingredients

Keywords: AEL; acceptable exposure level; AOO; acetone olive oil; CEL; consumer exposure level; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EC3; effective concentration of the test substance required to produce a three-fold increase in the stimulation index co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: Skin sensitisation

Keywords: ACD; allergic contact dermatitis; AEL; acceptable exposure level; APC; antigen presenting cells; CEL; consumer exposure level; CIR; cosmetic ingredient review; COLIPA; the European Cosmetics Association; DC; dendritic cells; DPRA; direct peptide reactivit

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Current and future use of genomics data in toxicology: Opportunities and challenges for regulatory applications

Keywords: BMD; benchmark dose; CAR; constitutive activated receptor; CFSAN; FDA center for food safety and applied nutrition; CTD; Comparative Toxicogenomics Database; DBP; dibutyl phthalate; eGOn; explore gene ontology; EPA; Environmental Protection Agency; EST; e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Exposure-driven risk assessment: Applying exposure-based waiving of toxicity tests under REACH

Keywords: AF; assessment factor; AI; active ingredient; BW; body weight; CoNTC; concentration of no toxicological concern; CSA; chemical safety assessment; CSR; chemical safety report; DNEL; derived no-effect level; DMEL; derived minimal effect level; EBW; exposure

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Integrated risk assessment of a hydroxyapatite-protein-composite for use in oral care products: A weight-of-evidence case study

Keywords: ANOVA; analysis of variance; ECETOC; European Centre for Ecotoxicology and Toxicology of Chemicals; ECVAM; European Center on the Validation of Alternative Methods; EPR; electron paramagnetic resonance; GCP; Good Clinical Practice; gd; glycerol/water disp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

An Integrated Assessment Scheme for assessing the adequacy of (eco)toxicological data under REACH

Keywords: OECD principles; Klimisch; (Q)SARs; WoE; ITS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

A weight of evidence approach for quality assessment of sediments impacted by an oil spill: The role of a set of biomarkers as a line of evidence

Keywords: PAHs; Contamination; Toxicity; Sublethal; WOE; Bioassay; Clam; Crab

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Using a classical weight-of-evidence approach for 4-years' monitoring of the impact of an accidental oil spill on sediment quality

Keywords: PAHs; Contamination; Toxicity; WOE; Sediment Quality Triad

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه