کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10962606 1102643 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vaccines against respiratory syncytial virus: The time has finally come
ترجمه فارسی عنوان
واکسنهای ضد ویروس تنفسی سونسیتیال: زمان به پایان رسیده است
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی
Respiratory syncytial virus causes a significant public health burden, particularly in very young infants and the frail elderly. The legacy of enhanced RSV disease (ERD) from a whole formalin-inactivated RSV vaccine, and the complex biology of the virus and the neonate have delayed the development of effective vaccines. However, new insights into factors associated with ERD and breakthroughs in understanding the antigenic structure of the fusion (F) glycoprotein have increased optimism that vaccine development is possible. This has led to investment of time and resources by industry, regulatory authorities, governments, and nonprofit organizations to develop the infrastructure needed to make the advanced clinical development of RSV vaccine candidates a reality.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 34, Issue 30, 24 June 2016, Pages 3535-3541
نویسندگان
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