Apolipoprotein E ɛ4 Genotype and Gender: Effects on Memory

The results demonstrate that recognition memory for olfactory stimuli may be particularly impaired in healthy older men with the ɛ4 allele. In patients with AD, odor memory impairments may be less severe in women who are negative for the ɛ4 allele. The results offer new insight into how recognition memory is affected by gender, the ɛ4 allele, and the modality of the stimulus to be remembered in healthy older adults and patients with AD.