کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3090611 1190281 2007 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Principes et intérêts pour l'étude des maladies neurologiques et technologie des puces ADN
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Principes et intérêts pour l'étude des maladies neurologiques et technologie des puces ADN
چکیده انگلیسی
In Neurooncology DNA microarrays should help to establish a more accurate classification of brain tumors and recent studies have shown how gene expression profiling of brain tumors allows to uncover previously unrecognized patient subsets that differ in their survival. The applications of microarrays for the study of neurological diseases, like multiple sclerosis, Alzheimer disease or neuromuscular diseases are also promising both for generating new pathophysiological hypotheses and for enabling new molecular classifications. DNA microarray genotyping is a powerful technology that should help to discover genetic factors associated with multifactorial neurological disorders and help to diagnose complex neurogenetic diseases. This technology should also facilitate the realization of pharmacogenomic studies in neurological diseases.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue Neurologique - Volume 163, Issue 4, April 2007, Pages 409-420
نویسندگان
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