کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3197852 | 1201874 | 2013 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report
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کلمات کلیدی
TLRTregAITSLITSCITAllergen immunotherapy - ایمنوتراپی آلرژنallergy immunotherapy - ایمونوتراپی آلرژیoral immunotherapy - ایمونوتراپی دهانsubcutaneous immunotherapy - ایمونوتراپی زیر جلدیSublingual immunotherapy - ایمونوتراپی زیر زبانیAtopic disease - بیماری اتوپیکimmune tolerance - تحمل ایمنی، تحمل ایمونولوژیکToll-like receptor - تیالآرOIT - سازمان بین المللی کارRegulatory T - مقررات T
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Allergy immunotherapy (AIT) is an effective treatment for allergic asthma and rhinitis, as well as venom-induced anaphylaxis. In addition to reducing symptoms, AIT can change the course of allergic disease and induce allergen-specific immune tolerance. In current clinical practice immunotherapy is delivered either subcutaneously or sublingually; some allergens, such as grass pollen, can be delivered through either route, whereas others, such as venoms, are only delivered subcutaneously. Both subcutaneous and sublingual immunotherapy appear to have a duration of efficacy of up to 12 years, and both can prevent the development of asthma and new allergen sensitivities. In spite of the advances with AIT, safer and more effective AIT strategies are needed, especially for patients with asthma, atopic dermatitis, or food allergy. Novel approaches to improve AIT include use of adjuvants or recombinant allergens and alternate routes of administration. As part of the PRACTALL initiatives, the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology nominated an expert team to develop a comprehensive consensus report on the mechanisms of AIT and its use in clinical practice, as well as unmet needs and ongoing developments in AIT. This resulting report is endorsed by both academies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 131, Issue 5, May 2013, Pages 1288-1296.e3
Journal: Journal of Allergy and Clinical Immunology - Volume 131, Issue 5, May 2013, Pages 1288-1296.e3
نویسندگان
A. Wesley MD, Moises A. MD, PhD, Thomas MD, Linda MD, Pascal MD, PhD, Marek MD, Harold MD, Cezmi A. MD,