کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3198607 1201895 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of asthma exacerbations on health care costs among asthmatic patients with moderate and severe persistent asthma
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Effect of asthma exacerbations on health care costs among asthmatic patients with moderate and severe persistent asthma
چکیده انگلیسی

BackgroundHealth care costs increase in patients with more severe asthma, but the effect of asthma exacerbations on costs among patients with more severe asthma has not been quantified.ObjectiveThis study compared direct health care costs between patients with moderate/severe persistent asthma with and without exacerbations.MethodsPatients who had an asthma diagnosis (International Classification of Diseases–ninth revision–Clinical Modification code 493.x), were 12 to 64 years old, and were receiving controller therapy were identified from a large administrative claims database. Patients were categorized as having moderate/severe persistent asthma and were further evaluated for exacerbations during a 12-month exacerbation identification period. Patients with 1 or more exacerbations (asthma-related inpatient or emergency department visit or corticosteroid prescription) were matched to patients without exacerbations on demographic characteristics and asthma severity. Total and asthma-related health care costs during the 1-year study period after the exacerbation index date were calculated.ResultsPatients with exacerbations had significantly higher total health care costs ($9223 vs $5011, P < .0001) and asthma-related costs ($1740 vs $847, P < .0001). The cost differences remained significant after controlling for patient differences by using multivariate models. Patients with exacerbations (n = 3830) had higher rates of sinusitis, allergy-related diagnoses or medications, pneumonia, and mental disorders and higher average Charlson Comorbidity Index scores at baseline. Patients with exacerbations filled their prescriptions for controllers more often and had higher asthma-related drug costs.ConclusionsPatients with moderate/severe persistent asthma who had exacerbations had higher total and asthma-related health care costs than those without exacerbations. Moreover, controller medication use was higher in patients with exacerbations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 129, Issue 5, May 2012, Pages 1229–1235
نویسندگان
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