کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6068948 | 1587133 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Clinical History-Driven Diagnosis of Allergic Diseases: Utilizing in vitro IgE Testing
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کلمات کلیدی
PPVMolecular allergensTotal IgE - IgE کلFood allergy - آلرژی غذاییAeroallergens - آلودگی هواIgE antibody - آنتیبادی IgEpositive predictive value - ارزش پیش بینی مثبتAllergic disease - بیماری آلرژیکClinical history - تاریخچه بالینیDrug Allergy - حساسیت به داروHymenoptera venom - زهر HymenopteraComponent - مولفه
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This case illustrates the importance of a thorough clinical history in providing an interpretation of previously collected IgE antibody serology as part of a workup for allergic disease. Although a yellow-jacket sting was the allergenic insult that led the patient to the emergency department, nonindicated IgE antibody serology tests were ordered that subsequently required interpretation. This report systematically evaluates the relative significance of previously measured IgE antibody serology responses to 4 major allergen groups (inhalants [aeroallergens], foods, venoms, and drugs) within the context of the patient's history. An algorithm that takes into account the pretest likelihood of disease and diagnostic sensitivity and specificity of the available IgE antibody tests is proposed for decisions about further IgE testing. This case study concludes that selection of testing methods, extract and molecular allergen specificities, and the final interpretation of the results from tests of sensitization such as serological (in vitro) IgE antibody assays requires knowledge of test parameters and clinical judgments based largely on a carefully collected clinical history and physical examination.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 3, Issue 6, NovemberâDecember 2015, Pages 871-876
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 3, Issue 6, NovemberâDecember 2015, Pages 871-876
نویسندگان
N. Franklin MD, Robert G. PhD,