کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6070047 1587507 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewEnd points in dermatologic clinical trials: A review for clinicians
ترجمه فارسی عنوان
نقد و بررسی نقاط در آزمایشات پوستی: بررسی برای پزشکان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
چکیده انگلیسی

Clinical trials are critical for the development of new therapies in dermatology, and their results help determine US Food and Drug Administration (FDA) approval and guide care. Of special relevance is the clinical trial efficacy end point, the metric from which statistically significant outcome is derived. Clinicians' understanding of a clinical trial's end point is necessary for critical analysis of the trial results and for applying those results to daily practice. This review provides practical knowledge and critical evaluation of end points used in treatment approvals by the FDA. The end points for actinic keratosis, acne vulgaris, atopic dermatitis, onychomycosis, and cutaneous ulcer serve as examples.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 75, Issue 1, July 2016, Pages 203-209
نویسندگان
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