Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4 Fulltext Access 6 Pages 2006
Fas ligand in bull ejaculated spermatozoa:A quantitative immunocytochemical study Fulltext Access 6 Pages 2006
Immunocytochemical study of cytoskeletal proteins in centronuclear myopathies Fulltext Access 6 Pages 2006
Stromal differences in salivary gland tumors of a common histopathogenesis but with different biological behavior: A study with picrosirius red and polarizing microscopy Fulltext Access 6 Pages 2006
Design and semisynthesis of novel fredericamycin A derivatives with an improved antitumor profile Fulltext Access 6 Pages 2006
Flexible synthesis and biological evaluation of novel 5-deoxyadenophorine analogues Fulltext Access 6 Pages 2006
Identification of novel PPARα ligands by the structural modification of a PPARγ ligand Fulltext Access 6 Pages 2006
Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands Fulltext Access 6 Pages 2006
Synthesis of pyrazoles and isoxazoles as potent αvβ3 receptor antagonists Fulltext Access 6 Pages 2006
Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity Fulltext Access 6 Pages 2006
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors Fulltext Access 6 Pages 2006
Carboxy derivatized glucosamine is a potent inhibitor of matrix metalloproteinase-9 in HT1080 cells Fulltext Access 6 Pages 2006
A possible role of Fas antigen in ejaculated spermatozoa of fertile bulls: an immunocytochemical quantitative approach Fulltext Access 6 Pages 2006
The discovery of tetrahydrofluorenones as a new class of estrogen receptor β-subtype selective ligands Fulltext Access 6 Pages 2006
DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B) Fulltext Access 6 Pages 2006
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity Fulltext Access 6 Pages 2006
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors Fulltext Access 6 Pages 2006
Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers Fulltext Access 6 Pages 2006
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of N,N′-bis[2-oxo-2H-benzopyran]-3-carboxamides Fulltext Access 6 Pages 2006
Identification of metabolites of the tryptase inhibitor CRA-9249: Observation of a metabolite derived from an unexpected hydroxylation pathway Fulltext Access 6 Pages 2006
Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors Fulltext Access 6 Pages 2006
P2–P4 Macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease Fulltext Access 6 Pages 2006
N-Acylated sulfonamide sodium salt: A prodrug of choice for the bifunctional 2-hydroxymethyl-4-(5-phenyl-3-trifluoromethyl-pyrazol-1-yl) benzenesulfonamide class of COX-2 inhibitors Fulltext Access 6 Pages 2006
Blood supply of colorectal polyps correlates with risk of bleeding after colonoscopic polypectomy Fulltext Access 6 Pages 2006
Yield of tissue sampling for subepithelial lesions evaluated by EUS: a comparison between forceps biopsies and endoscopic submucosal resection Fulltext Access 6 Pages 2006
Unsedated ultrathin EGD by using a 5.2-mm-diameter videoscope: evaluation of acceptability and diagnostic accuracy Fulltext Access 6 Pages 2006
The yield of wireless capsule endoscopy in the detection of neuroendocrine tumors in comparison with CT enteroclysis Fulltext Access 6 Pages 2006
Complete endoscopic closure of gastric perforation induced by endoscopic resection of early gastric cancer using endoclips can prevent surgery (with video) Fulltext Access 6 Pages 2006
Evaluation of a new technique for endoscopic nasojejunal feeding-tube placement Fulltext Access 6 Pages 2006
Colorectal neoplasia in veterans is associated with Barrett's esophagus but not with proton-pump inhibitor or aspirin/NSAID use Fulltext Access 6 Pages 2006
Successful endoscopic en bloc resection of a large laterally spreading tumor in the rectosigmoid junction by endoscopic submucosal dissection Fulltext Access 6 Pages 2006
Double-balloon enteroscopy in the diagnosis and the management of small-bowel diseases: an initial experience in 40 patients Fulltext Access 6 Pages 2006
Histologic results of EMR for esophageal lesions diagnosed as high-grade intraepithelial squamous neoplasia by endoscopic biopsy Fulltext Access 6 Pages 2006
Estrogen receptor β-subtype selective tetrahydrofluorenones: Use of a fused pyrazole as a phenol bioisostere Fulltext Access 6 Pages 2006
EUS-guided fiducial placement for CyberKnife radiotherapy of mediastinal and abdominal malignancies Fulltext Access 6 Pages 2006
Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance Fulltext Access 6 Pages 2006
Human growth hormone and interleukin-6 are upregulated in endometriosis and endometrioid adenocarcinoma Fulltext Access 6 Pages 2006
Localization of group-1 allergen Zea m 1 in the coat and wall of maize pollen Fulltext Access 6 Pages 2006
Sensitivity and specificity of Congo red staining according to Romhányi. Comparison with Puchtler's or Bennhold's methods Fulltext Access 6 Pages 2006
Identification of an indole series of prostaglandin D2 receptor antagonists Fulltext Access 6 Pages 2006
Neuraminidase pharmacophore model derived from diverse classes of inhibitors Fulltext Access 6 Pages 2006
Design, synthesis, and preliminary biological evaluation of 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine derivatives Fulltext Access 6 Pages 2006
Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors Fulltext Access 6 Pages 2006
Structure–activity relationships of novel antibacterial translation inhibitors: 3,5-Diamino-piperidinyl triazines Fulltext Access 6 Pages 2006
Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity Fulltext Access 6 Pages 2006
Synthesis and biological evaluation of heterocycle containing adamantane 11β-HSD1 inhibitors Fulltext Access 6 Pages 2006
Synthesis and structural activity relationship of 11β-HSD1 inhibitors with novel adamantane replacements Fulltext Access 6 Pages 2006
Synthesis and structure–activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents Fulltext Access 6 Pages 2006
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine Fulltext Access 6 Pages 2006
Electrochemiluminescence determination of pipemidic acid using sulfite as energy transfer mediator Fulltext Access 6 Pages 2006
Ureas with histamine H3-antagonist receptor activity—A new scaffold discovered by lead-hopping from cinnamic acid amides Fulltext Access 6 Pages 2006
Design, synthesis, and preliminary biological evaluation of novel ethyl 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carboxylate Fulltext Access 6 Pages 2006
Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands Fulltext Access 6 Pages 2006
Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations Fulltext Access 6 Pages 2006
Improved 3D-QSAR CoMFA of the dopamine transporter blockers with multiple conformations using the genetic algorithm Fulltext Access 6 Pages 2006
Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers Fulltext Access 6 Pages 2006
Total synthesis and biological evaluation of viscolin, a 1,3-diphenylpropane as a novel potent anti-inflammatory agent Fulltext Access 6 Pages 2006
First dual M3 antagonists-PDE4 inhibitors: Synthesis and SAR of 4,6-diaminopyrimidine derivatives Fulltext Access 6 Pages 2006
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors Fulltext Access 6 Pages 2006
Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes Fulltext Access 6 Pages 2006
Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties Fulltext Access 6 Pages 2006
Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors Fulltext Access 6 Pages 2006
Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors Fulltext Access 6 Pages 2006
Arylmethoxypyridines as novel, potent and orally active mGlu5 receptor antagonists Fulltext Access 6 Pages 2006
Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors Fulltext Access 6 Pages 2006
Potent blockers of the monocarboxylate transporter MCT1: Novel immunomodulatory compounds Fulltext Access 6 Pages 2006
Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (−)-dysiherbaine Fulltext Access 6 Pages 2006
Matrix compare analysis discriminates subtle structural differences in a family of novel antiproliferative agents, diaryl-3-hydroxy-2,3,3a,10a-tetrahydrobenzo[b]cycylopenta[e]azepine-4,10(1H,5H)-diones Fulltext Access 6 Pages 2006
Inhibitors of human mitotic kinesin Eg5: Characterization of the 4-phenyl-tetrahydroisoquinoline lead series Fulltext Access 6 Pages 2006
Synthesis and structure–activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor Fulltext Access 6 Pages 2006