Keywords: تمرین خوب آزمایشگاهی; FTIH; first time in human; PP-HOP; pleural pressure-head out plethysmography; WBP; whole body plethysmography; i.t.; intra tracheal; VT; tidal volume; Bpm; breaths per minute; MV; minute volume; ICH; The International Council for Harmonisation of Technica
مقالات ISI تمرین خوب آزمایشگاهی (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: تمرین خوب آزمایشگاهی; CIGAA; consortium for the investigation of genotoxicity of aromatic amines; GLP; good laboratory practice; KNIME; the Konstanz Information Miner; pAAs; primary aromatic amines; (Q)SAR; quantitative structure-activity relationship; SMARTS; SMiles ARbitrary
Keywords: تمرین خوب آزمایشگاهی; Safety; Preclinical; Rodent; Salicylamine; γ-Ketoaldehydes; 2-HOBA; 2-hydroxybenzylamine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BUN; blood urea nitrogen; BW; body weight; FDA; Food and Drug Administration; GLP; good laboratory p
Keywords: تمرین خوب آزمایشگاهی; CV; coefficient of variation; CS; calibration standard; DMSO; dimethylsulfoxide; EMA; European Medicine Agency; FDA; Food and Drug Administration; GCP; Good Clinical Practice; GLP; Good Laboratory Practice; IS; internal standard; K3EDTA; tripotassium ethy
Keywords: تمرین خوب آزمایشگاهی; Mulberry leaf extract; Rat; Subacute toxicity; Genotoxicity; Ames assay; Micronucleus; Sperm abnormality; Safety assessment; 1,8-DHAQ; 1,8-dihydroxyanthraquinone; 2-AF; 2-aminofluorene; 4-NO; 4-nitro-O-phenylenediamine; ALB; albumin; ALP; alkalinephosphat
Keywords: تمرین خوب آزمایشگاهی; Genotoxicity; Isoquercitrin; Enzymatically-modified isoquercitrin; Flavonol; DNA damage; Food additive; AGIQ; alpha-glycosyl isoquercitrin; CGTase; cyclodextrin glucanotransferase; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EFSA; Eur
Keywords: تمرین خوب آزمایشگاهی; Hydrogen peroxide; Photolysis; Hydroxyl radicals; Periodontal therapy; Oral mucosa irritation; Hamster; GLP; good laboratory practice; ISO; International Organization for Standardization;
Keywords: تمرین خوب آزمایشگاهی; Hollow micro-needle; Resistance pressure; Drug delivery; eb; evans blue; Di; deionization; Km; kunming; Asp; ammonium persulfate; Temed; n,n,n',n'-tetramethylethylenediamine; SDS-PAGE; Sodium dodecyl sulfate polyacrylamide gel electrophoresis; GLP; Good l
Keywords: تمرین خوب آزمایشگاهی; AT; ataxia telangiectasia; DSP; dexamethasone sodium phosphate; EDS; EryDex system; EDS-EP; EDS end product; GLP; good laboratory practice; GMP; good manufacturing practice; HCT; hematocrit; HD; healthy donor; HGB; hemoglobin; HPLC; high-performance liqui
Keywords: تمرین خوب آزمایشگاهی; ventricular assist device (VAD); continuous-flow device; pediatrics; mechanical circulatory support (MCS); pediatrics heart transplantation; ACT; activated clotting time; FDA; Food and Drug Administration; GLP; good laboratory practice; IDE; Investigation
Keywords: تمرین خوب آزمایشگاهی; Graphene-based nanomaterials; Graphene; Graphene oxide; Reduced graphene oxide; Graphene quantum dots; Toxicity; Inflammation; Biodistribution; In vivo; Ach; acetylcholine; ADD; aerodynamic diameter; AgD; agglomerate density; AgS; Agglomerate size; ApD;
Keywords: تمرین خوب آزمایشگاهی; Thiophene; Flavoring ingredients; FEMA GRAS; bw; body weight; CYP; cytochrome P450; DNA; deoxyribonucleic acid; DT; decision tree; F; female; FEMA; the Flavor and Extract Manufacturers Association; GLP; good laboratory practice; GRAS; generally recognized
Keywords: تمرین خوب آزمایشگاهی; TB; tuberculosis; MTB; Mycobacterium tuberculosis; MDR-TB; multi-drug resistant tuberculosis; XDR-TB; extensively drug resistant tuberculosis; TDR-TB; totally drug resistant tuberculosis; INH; isoniazid; WHO; World Health Organization; RIF; rifampicin; PZ
Keywords: تمرین خوب آزمایشگاهی; ISO 15189; Molecular diagnostics; Infectious diseases; Oncology; Inherited diseases; Pharmacogenomics; Molecular requisition; Informed consent; Specimen integrity; Molecular pathology; Standardization; Good laboratory practice; Pre-analytic; Pre-examinati
Keywords: تمرین خوب آزمایشگاهی; ACC; American College of Cardiology; acLDL; acetylated-low density lipoprotein; AHA; American Heart Association; ALL; acute lymphoblastic leukemia; ANG1; angiopoietin 1; ATMP; Advanced Therapy Medicinal Product; BM; bone marrow; BMSC; bone marrow-derived
Keywords: تمرین خوب آزمایشگاهی; Honokiol microemulsion; Cerebral ischemia protection; Embryo-fetal development toxicity; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; GD; gestation day; GLP; Good Laboratory Practice; ICH; International Conference on Har
Keywords: تمرین خوب آزمایشگاهی; Aspartame; Genotoxicity in vitro; Genotoxicity in vivo; CA; chromosomal aberrations; CBPI; cytokinesis-block proliferation index; EFSA; European Food Safety Authority; GLP; Good Laboratory Practice; ICH; International Conference on Harmonization of Tech
Keywords: تمرین خوب آزمایشگاهی; GLP; good laboratory practice; M:E ratio; myeloid:erythroid ratio; NOS; no otherwise specified; Background findings; Bone marrow; Mice; Rats; Rodents;
Keywords: تمرین خوب آزمایشگاهی; 2-AA; 2-aminoanthracene; 2-NF; 2-nitrofluorene; 9-AA; 9-aminoacridine; ARA; arachidonic acid; bw; body weight; CBPI; cytokinesis-blocked proliferation index; DHA; docosahexaenoic acid; DMSO; dimethyl sulfoxide; F1; first generation; FOB; functional observ
Keywords: تمرین خوب آزمایشگاهی; α-GST; alpha-glutathione S-transferase; B2M; beta-2 microglobulin; BUN; blood urea nitrogen; CROs; contract research organisations; Cr; creatinine; CysC; cystatin C; DIKI; drug-induced kidney-injury; EFPIA; European Federation of Pharmaceutical Industrie
Keywords: تمرین خوب آزمایشگاهی; Genotoxicity; Cobalt compounds; Overall assessment; 2-AA; 2-aminoanthracene; 2NF; 2-nitrofluorene; 4-NOPD; nitro-o-phenylenediamine; 6Â TG; 6-thioguanine; 8-OH-dG; 8-hydroxy-2-deoxyguanosine; 9AA; 9-aminoacridine; AAF; artificial alveolar fluid; B[a]P; be
Keywords: تمرین خوب آزمایشگاهی; 3T3 NRU PT; 3T3 neutral red uptake phototoxicity test; 8-MOP; 8-methoxypsoralen; CV; coefficient of variation; ECVAM; Europe Center for the Validation of Alternative Methods; GLP; Good Laboratory Practice; ICCVAM; Interagency Coordinating Committee on the
Keywords: تمرین خوب آزمایشگاهی; Microalgae; Fermentation; Oleic-rich oil; Genotoxic; Mutagenic; Subchronic toxicity; 2-AA; 2-aminoanthracene; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care International; ANOVA; Analysis of Variance; AOAC; Association of A
Keywords: تمرین خوب آزمایشگاهی; ADC; antibody-drug conjugate; ADME; absorption, distribution, metabolism and elimination; EFD; embryofetal development; ELISA; enzyme-linked immunosorbent assay; FIH; first-in-human; GLP; Good Laboratory Practice; hERG; human ether-Ã -go-go related gene;
Keywords: تمرین خوب آزمایشگاهی; 3Rs; replacement, refinement and reduction of animals in research; ACSA; Agricultural Chemicals Safety Assessment; ADA; anti-drug antibody; CNS; central nervous system; DBS; dried blood spot; DART; developmental and reproductive toxicity; DRF; dose range
28-day inhalation toxicity of 3-methoxybutyl chloroformate in rats
Keywords: تمرین خوب آزمایشگاهی; ANOVA; analysis of variance; CT; computed tomography; EDTA; ethylenediamine tetraacetic acid; GHS; Globally Harmonized System of Classification and Labelling of Chemicals; GLP; Good Laboratory Practice; HCT; hematocrit; HGB; hemoglobin concentration; MCH;
Assessing the safety of an Ephedrae Herba aqueous extract in rats: A repeat dose toxicity study
Keywords: تمرین خوب آزمایشگاهی; Repeated dose toxicity; Safety assessment; Ephedrae Herba; F344 rats; NOAEL; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; bw; body weight; BUN; blood urea nitrogen; CREA; creatinine; GLU; glucose; LUC; large u
Extractability-mediated stability bias and hematocrit impact: High extraction recovery is critical to feasibility of volumetric adsorptive microsampling (VAMS) in regulated bioanalysis
Keywords: تمرین خوب آزمایشگاهی; VAMS; volumetric absorptive microsampling; Ht; hematocrit; LLE; liquid-liquid extraction; GLP; good laboratory practice; LC-MS/MS; liquid chromatography coupled with triple quadrupole mass spectrometry; LLOQ; lower limit of quantification; ULOQ; upper
Microdialysis combined with RRLC-MS/MS for the pharmacokinetics of two major alkaloids of Bi qi capsule and the potential roles of P-gp and BCRP on their penetration
Keywords: تمرین خوب آزمایشگاهی; BQC; Bi qi capsule; BBB; blood-brain barrier; RRLC-MS/MS; rapid resolution liquid chromatography -tandem mass spectrometry; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; CNS; central nervous system; CSF; cerebrospinal fluid; LLOQ; lower li
Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin
Keywords: تمرین خوب آزمایشگاهی; Genotoxicity; Gardenia blue; Genipin; DNA damage; Food colorant; DNA crosslinking; DMSO; (dimethyl sulfoxide); EFSA; European Food Safety Authority; (EMS); ethyl methanesulfonate; FDA; US Food and Drug Administration; GLP; Good Laboratory Practice; MN; mi
Quantitative evaluation of the matrix effect in bioanalytical methods based on LC-MS: A comparison of two approaches
Keywords: تمرین خوب آزمایشگاهی; AAPS; American Association of Pharmaceutical Scientists; CV(%); coefficient of variation; EMA; European Medicines Agency; FDA; U.S. Food and Drug Administration; GLP; good laboratory practice; IS; internal standard; IS-norm; internal standard normalized;
In vitro secondary pharmacological profiling: An IQ-DruSafe industry survey on current practices
Keywords: تمرین خوب آزمایشگاهی; AUC; Area Under the Curve; CRO; Contract Research Organization; CTA; Clinical Trial Authorization; GLP; Good Laboratory Practice; hERG; human ether-a-go-go-related gene; ICH; International Conference on Harmonization; IND; Investigational New Drug; IQ; In
Bile salt enhancers for inhalation: Correlation between in vitro and in vivo lung effects
Keywords: تمرین خوب آزمایشگاهی; ADSA; axisymmetric drop shape analysis; ATP; adenosine triphosphate; APIs; active pharmaceutical ingredients; BPM; breaths per minute; bw; body weight; CDS; constrained drop surfactometer; CMC; critical micelle concentration; DMSO; dimethylsulfoxid; GLP;
A 14-day repeated-dose oral toxicological evaluation of an isothiocyanate-enriched hydro-alcoholic extract from Moringa oleifera Lam. seeds in rats
Keywords: تمرین خوب آزمایشگاهی; ANOVA; analysis of variance; GLP; good laboratory practice; ITC; isothiocyanate; MIC-1; moringa isothiocyanate-1; MICs; moringa isothiocyanates; MSE; moringa seed extract; NF-κB; nuclear factor kappa B; NO; nitric oxide; NOAEL; no observed adverse effect
In vitro and in vivo safety studies of cinnamon extract (Cinnamomum cassia) on general and genetic toxicology
Keywords: تمرین خوب آزمایشگاهی; Cinnamomum cassia; Cinnamon; Toxicity; Subchronic; Genotoxicity; GLP; Good Laboratory Practice; OECD; Organization for Economic Co-operation and Development; WBC; white blood cell; RBC; red blood cell; HGB; hemoglobin; HCT; hematocrit; PLT; platelet; MCV;
CON4EI: EpiOcular⢠Eye Irritation Test (EpiOcular⢠EIT) for hazard identification and labelling of eye irritating chemicals
Keywords: تمرین خوب آزمایشگاهی; DBALM; Database of Alternative Methods at the European Commission's Joint Research Centre; Cat 1; UN GHS/EU CLP classification for chemicals causing irreversible effects on the eye/serious damage to the eye; Cat 2; UN GHS/EU CLP classification for chemica
Safety evaluation of a mixture of the human-identical milk oligosaccharides 2â²-fucosyllactose and difucosyllactose
Keywords: تمرین خوب آزمایشگاهی; 2â²-fucosyllactose; Difucosyllactose; Lactodifucotetraose; Human-identical milk oligosaccharide; Infant formula; Safety; 2-AA; 2-aminoanthracene; 2â²-FL; 2â²-fucosyllactose; 2â²-FL/DFL; 2â²-fucosyllactose/difucosyllactose mixture; 2-NF; 2-nitroflouri
Magnesium stearate, a widely-used food additive, exhibits a lack of in vitro and in vivo genotoxic potential
Keywords: تمرین خوب آزمایشگاهی; 2AA; 2-aminoanthracene; 9AA; 9-aminoacridine hydrochloride monohydrate; ADI; acceptable daily intake; AF-2; 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide; DMSO; dimethyl sulfoxide; EFSA; European Food Safety Authority; FAO; Food and Agriculture Organization
Identification of appropriate QTc formula in beagle dogs for nonclinical safety assessment
Keywords: تمرین خوب آزمایشگاهی; Beagle dogs; Electrocardiogram; Heart rate; QT correction formula; Preclinical assessment; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; ECG; Electrocardiogram; GLP; Good Laboratory Practice; HR; Heart Rate; ICH; Internat
Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine
Keywords: تمرین خوب آزمایشگاهی; ACN; acetonitrile; BER; base excision repair; C.V.; coefficient of variation; DMSO; dimethylsulfoxide; DSB; double strand break; EMA; European Medicine Agency; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; HRR; homologous recombination
Absence of subchronic oral toxicity and genotoxicity of rice koji with Aspergillus terreus
Keywords: تمرین خوب آزمایشگاهی; Aspergillus terreus; Koji; Fermented food; Functional food; Toxicity; Subchronic; Genotoxicity; NOAEL; no-observed-adverse-effect level; OECD; Organization for Economic Co-operation and Development; GLP; Good Laboratory Practice; WBC; white blood cell; RB
An FDA oncology analysis of CD3 bispecific constructs and first-in-human dose selection
Keywords: تمرین خوب آزمایشگاهی; CD3 bispecific; MABEL; First-in-human dose; Oncology drug development; FIH; first-in-human; CRA; cytokine release assay; CRS; cytokine release syndrome; GLP; good laboratory practice; HHD; highest human dose; HNSTD; highest non-severely toxic dose; IB; In
Framework for the quality assurance of 'omics technologies considering GLP requirements
Keywords: تمرین خوب آزمایشگاهی; Good laboratory practice (GLP); Standard operating procedure; Independent quality assurance; Documentation; Data storage; Reproducibility; Raw data definition; Software validation; Quality assurance inspection; ECETOC; European Centre for Ecotoxicology an
Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
Keywords: تمرین خوب آزمایشگاهی; Furan; Tumorigenicity; Cholangiocarcinoma; Cholangiofibrosis; Rats; Bioassay; BMD; benchmark dose; BMDL; lower limit of benchmark dose; BW; body weight; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; MOE; margin of exposure; NCTR; Natio
The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook
Keywords: تمرین خوب آزمایشگاهی; Omics; Transcriptomics; Weight-of-evidence; Registration, Evaluation, Authorisation, and Restriction (REACH); Plant protection products; Regulatory toxicology; Hazard assessment; Test method validation; Test method standardisation; AOP; Adverse outcome pa
A 90-day oral toxicity study of glycolipids from Dacryopinax spathularia in CD® rats
Keywords: تمرین خوب آزمایشگاهی; Oral; Subchronic toxicity; Rat; Jelly mushroom glycolipids; Natural preservative; Absorption, distribution, metabolism, and excretion; (ADME); activated partial thromboplastin time; (aPTT); alanine amino-transferase; (ALAT); alkaline phosphatase; (AP); as
Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys
Keywords: تمرین خوب آزمایشگاهی; AKI; acute kidney injury; ALB; albumin; α1M; alpha 1 microglobulin; αGST; alpha glutathione S-transferase; β2M; beta 2 microglobulin; BUN; blood urea nitrogen; CALB; calbindin D28k; CLU; clusterin; Cr; creatinine; CYS C; cystatin C; DIKI; drug-induced
Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop
Keywords: تمرین خوب آزمایشگاهی; Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse
Detection of ECG effects of (2R,4R)-monatin, a sweet flavored isomer of a component first identified in the root bark of the Sclerochitin ilicifolius plant
Keywords: تمرین خوب آزمایشگاهی; (2R,4R)-Monatin; QT prolongation; QTc; TQT study; Food ingredient; ADME; absorption, distribution, metabolism, and elimination; AE; adverse event; Ae; amounts excreted; AUC0-inf; area under the plasma concentration-time curve to infinite time; AUC0-t; a
High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells
Keywords: تمرین خوب آزمایشگاهی; DILI; drug-induced liver injury; GLP; good laboratory practice; HCA; high content analysis; ROS; reactive oxygen species; GSH; glutathione; MMP; mitochondrial membrane potential; MP; membrane permeability; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dich