Keywords: عامل هسته ای هپاتوسیت; Resistin-like molecule; Macrophage; Helminth infection; T helper type 2; Toll-like Receptor 4; ABC; ATP-binding cassette transporter; ADD1; adipocyte determination and differentiation dependent factor 1; ADSF; adipocyte secreted factor; Akt (aka PKB); pro
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Keywords: عامل هسته ای هپاتوسیت; 11βHSD; 11β-Hydroxysteroid dehydrogenase; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; BCRP; breast cancer resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P45
Keywords: عامل هسته ای هپاتوسیت; Hepatocyte nuclear factor; Liver; Transcription; Regulatory network; Development; MODY; Disease;
Keywords: عامل هسته ای هپاتوسیت; BMP; Bone Morphogenic Protein; Cdx2; caudal type homeobox 2; C/EBP; CCAAT/Enhancer Binding Protein; ES; embryonic stem; FGF; Fibroblast Growth Factor; FoxA; Forkhead box factor A; GRN; gene regulatory network; Grg3; groucho-related gene 3; HNF; Hepatocyte
Keywords: عامل هسته ای هپاتوسیت; ALS; acid-labile subunit; CIS; cytokine-inducible SH2-containing protein; E2; estradiol; ER; endoplasmic reticulum; ERK; extracelular regulated kinase; ESPE; European Society for Pediatric Endocrinology; GH; growth hormone; GHBP; growth hormone binding pr
Keywords: عامل هسته ای هپاتوسیت; 2210010C04Rik; RIKEN cDNA 2210010C04 gene; 5330417C22Rik; RIKEN cDNA 5330417C22 gene; A1AT; alpha1-antitrypsin; Ago1; argonaute RISC catalytic component 1; Amy2a5; amylase 2a5; Amy2b; amylase, alpha 2B; AP1/JUN; jun proto-oncogene; Bmp; bone morphogenetic
Keywords: عامل هسته ای هپاتوسیت; Extracellular matrix; Human embryonic stem cell; Human induced pluripotent stem cell; Hepatic differentiation; Laminin-511; Laminin-521; ACM; acellular matrix; Act A; Activin A; AAT; alpha-1 antitrypsin; AFP; alpha fetoprotein; ALB; albumin; AhR; aryl hyd
Keywords: عامل هسته ای هپاتوسیت; ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Keywords: عامل هسته ای هپاتوسیت; Cholesterol metabolism; Lipoproteins; Liver; Transcription; Dyslipidemia; ABCA1; ATP-binding cassette transporter A1; ACAT2; acyl-Coenzyme A:cholesterol acyltransferase 2; apo; apolipoprotein; CYP7A1; cholesterol 7α-hydroxylase; HMGCR; 3-hydroxy-3-methyl
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Keywords: عامل هسته ای هپاتوسیت; Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon
Differentiation in stem/progenitor cells along fetal or adult hepatic stages requires transcriptional regulators independently of oscillations in microRNA expression
Keywords: عامل هسته ای هپاتوسیت; AH; adult hepatocyte; Alb; albumin; AFP; alpha-fetoprotein; CK; cytokeratin; DDPIV; dipeptidylpeptidase IV; ELD; expression level dominance; EpCAM; epithelial cell adhesion molecule; FH; fetal hepatocyte; GDF; growth differentiation factor; GGT; gamma-glu
Collagenase-1 (-1607 1G/2G), Gelatinase-A (-1306 C/T), Stromelysin-1 (-1171 5A/6A) functional promoter polymorphisms in risk prediction of type 2 diabetic nephropathy
Keywords: عامل هسته ای هپاتوسیت; C/EBP; CCAAT-enhancer-binding protein; DN; Diabetic Nephropathy; ECM; Extracellular matrix; ELK; Extracellular signal like kinase; GBM; Glomerular basement membrane; GFR; Glomerular filtration rate; HNF; Hepatocyte Nuclear Factor; LD; Linkage Disequilibri
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
Keywords: عامل هسته ای هپاتوسیت; Posttranscriptional regulation; Transcription Factor; NAFLD; NASH; antagomiR; an inhibitor of miR; β-HB; β-hydroxybutyrate; BODIPY; boron-dipyrromethene; CL; CL316243; FFA; free fatty acid; HCC; hepatocellular carcinoma; HFD; high-fat diet; HNF; hepatoc
Baicalin benefits the anti-HBV therapy via inhibiting HBV viral RNAs
Keywords: عامل هسته ای هپاتوسیت; Baicalin; Anti-HBV; Nucleoside analog; HBV RNAs; Hepatocyte nuclear factors; BA; baicalin; HBV; hepatitis B virus; NAs; nucleoside analogs; ETV; entecavir; HNF; hepatocyte nuclear factor; qPCR; quantitative real-time PCR; pgRNA; pre-genomic RNA; DHBV; duc
SP and KLF Transcription Factors in Digestive Physiology and Diseases
Keywords: عامل هسته ای هپاتوسیت; Specificity Protein; Krüppel-Like Factor; Digestive System; Cancer; Stem Cells; Proliferation; Differentiation; Development; Apoptosis; Cell Cycle; APC; adenomatous polyposis coli; BAX; B-cell lymphoma 2-like protein 4; BCL2; B-cell lymphoma 2; COX2; c
ReviewAlpha-foetoprotein (AFP): A multi-purpose marker in hepatocellular carcinoma
Keywords: عامل هسته ای هپاتوسیت; AFP; alpha-foetoprotein; C/EBP; CCAAT/enhancer binding protein; CTC; circulating tumour cells; eIF-2α; eukaryotic translation initiation factor-2α; HCC; hepatocellular carcinoma; HNF; Hepatocyte Nuclear Factor; IRE-1α; Inositol-Requiring Enzyme-1α; mi
Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction
Keywords: عامل هسته ای هپاتوسیت; Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA
Searching for Maturity-Onset Diabetes of the Young (MODY): When and What for?
Keywords: عامل هسته ای هپاتوسیت; deletion; glucokinase; hepatocyte nuclear factor; maturity-onset diabetes of the young (MODY); monogenic diabetes; potassium channel; délétion; glucokinase; facteur nucléaire des hépatocytes; diabète de la maturité chez le sujet jeune (MODY); diabè
Research ArticleStage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes
Keywords: عامل هسته ای هپاتوسیت; HPSCs; human pluripotent stem cells; GI; gastrointestinal; FGF4; fibroblast growth factor 4; WNT; wingless-type MMTV integration site family; PFG; posterior foregut; HNF; hepatocyte nuclear factor; HHEX; hematopoietically-expressed homeobox protein; AFP;
Insights into CYP2B6-mediated drug-drug interactions
Keywords: عامل هسته ای هپاتوسیت; CAR; constitutive androstane receptor; C/EBP; CCAAT/enhancer-binding protein; CHOP; cyclophosphamide-doxorubicin-vincristine-prednisone; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime); COUP-TF; chic
Phenobarbital reduces blood glucose and gluconeogenesis through down-regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression in rats
Keywords: عامل هسته ای هپاتوسیت; PEPCK; Phenobarbital; Blood glucose; Pyruvate challenge; Diabetes; Hepatocyte; apo; apolipoprotein; AUC; area under the curve; CAR; constitutive androstane receptor; CAT; chloramphenicol acetyltransferase; CREB; cAMP response element binding protein; CYP;
Alginate oligosaccharide enhances LDL uptake via regulation of LDLR and PCSK9 expression
Keywords: عامل هسته ای هپاتوسیت; AOS; alginate oligosaccharide; CVD; cardiovascular disease; FH; familial hypercholesterolemia; GSK3β; glycogen synthase kinase 3β; HINFP; histone nuclear factor P; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; HNF; hepatocyte nuclear factor; Insig; in
Liver maturation deficiency in p57Kip2â/â mice occurs in a hepatocytic p57Kip2 expression-independent manner
Keywords: عامل هسته ای هپاتوسیت; Afp; α-fetoprotein; Bmp; bone morphogenic proteins; C/EBPα; CCAAT/enhancer-binding protein α; CK; cytokeratin; CKI; cyclin-dependent kinase inhibitor; Cyp; cytochrome P450; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; Dlk1; delta-like 1 homol
Alteration of the microRNA-122 regulatory network in rat models of hepatotoxicity
Keywords: عامل هسته ای هپاتوسیت; CT, carbon tetrachloride; TA, thioacetamide; LETF, liver enriched transcription factor; NRQ, normalized relative expressionmicroRNA-122; Hepatotoxicity; Carbon tetrachloride; Thioacetamide; CCAAT/enhancer-binding protein alpha; Hepatocyte nuclear factor
Research ArticleLiver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α
Keywords: عامل هسته ای هپاتوسیت; NR1H3; liver X receptor α; HNF; hepatocyte nuclear factor; MSCs; mesenchymal stem cells; ESCs; embryonic stem cells; iPSCs; induced pluripotent stem cells; RT; reverse-transcription; ChIP; chromatin immunoprecipitation; Hepatogenesis; LXRα/NR1H3; HNF4A;
Serine 249 phosphorylation by ATM protein kinase regulates hepatocyte nuclear factor-1α transactivation
Keywords: عامل هسته ای هپاتوسیت; HNF; hepatocyte nuclear factor; MODY; maturity onset diabetes of the young; ATM; ataxia telangiectasia mutated; EMSA; electrophoretic mobility shift assay; ChIP; chromatin immunoprecipitation; IB; immunoblot; R.L.U; relative luciferase units; HNF1α; ATM;
Cutl1: A potential target for cancer therapy
Keywords: عامل هسته ای هپاتوسیت; CDP; CCAAT displacement protein; HCC; human hepatocellular carcinoma; LETFs; liver-enriched transcription factors; HNF; hepatocyte nuclear factor; Shh; Sonic hedgehog; C/EBPα; CCAAT/enhancer-binding protein; MMTV; mouse mammary tumor virus; PCAF; p300/CR
Let-7b and miR-495 Stimulate Differentiation and Prevent Metaplasia of Pancreatic Acinar Cells by Repressing HNF6
Keywords: عامل هسته ای هپاتوسیت; Mouse Model; Pancreatic Development; Proliferation; Gene Regulation; Amy; amylase; Apo; apolipoprotein; Cel; carboxyl-ester lipase; CK19; cytokeratin 19; Cpa; carboxypeptidase A; E; embryonic day; GFP; green fluorescent protein; HNF; hepatocyte nuclear fa
Injury-Induced Changes in Liver Specific Transcription Factors HNF-1α and HNF-4α
Keywords: عامل هسته ای هپاتوسیت; hepatocyte nuclear factor; DNA-protein binding; cytokine; acute phase protein; burn injury
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
Keywords: عامل هسته ای هپاتوسیت; BMP; bone morphogenic protein; EHD; extrahepatic duct; EPD; extrapancreatic duct; FGF; fibroblasts growth factor; GB; gall bladder; HNF; hepatocyte nuclear factor; HPD; hepatopancreatic ductal system; IHD; intrahepatic ducts; IPD; intrapancreatic ducts; S
ReviewDevelopment of the bile ducts: Essentials for the clinical hepatologist
Keywords: عامل هسته ای هپاتوسیت; GW; week of gestation; Sox9; SRY-related HMG box transcription factor 9; K; cytokeratin; HNF; hepatocyte nuclear factor; TGF; transforming growth factor; TβRII; transforming growth factor receptor type II; PCP; planar cell polarity; IL; interleukin; Hh;
Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis
Keywords: عامل هسته ای هپاتوسیت; Akt/PKB; acutely transforming retrovirus AKT8 in rodent T cell lymphoma/protein kinase B; AMPK; AMP-activated protein kinase; CBP; CREB-binding protein; C/EBP; CCAAT enhancer binding protein; CNS; central nervous system; CREB; cAMP-responsive binding prot
Estrogen Receptor α Represses Transcription of HBV Genes via Interaction With Hepatocyte Nuclear Factor 4α
Keywords: عامل هسته ای هپاتوسیت; Hormone; Viral Replication; Mouse Model; Sex Differences; ChIP; chromatin immunoprecipitation; DBD; DNA-binding domain; ER; estrogen receptor; ERE; estrogen-responsive element; HDAC; histone deacetylase; HNF; hepatocyte nuclear factor; OVX; ovariectomy; S
Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates
Keywords: عامل هسته ای هپاتوسیت; cAMP; cyclic adenosine monophosphate; ERK; extracellular signal-regulated kinase; E2; 17β-estradiol; GH; growth hormone; GHR; growth hormone receptor; GHBP; growth hormone binding protein; HNF; hepatocyte nuclear factor; IGF; insulin-like growth factor;
Strategies for effective oral insulin delivery with modified chitosan nanoparticles: A review
Keywords: عامل هسته ای هپاتوسیت; ADA; American Diabetes Association; AE; association efficiency; BBI; Bowman-Birk inhibitor; CD; cyclodextrin; β-CD; β-cyclodextrin; CMC; carboxymethyl cellulose; CP-β-CD; cationic-β-CD polymer; DD; degree of deacetylation; DM; diabetes mellitus; DME
Genetic defects in Portuguese families with inherited protein C deficiency
Keywords: عامل هسته ای هپاتوسیت; PC; protein C; PS; protein S; FVa; activated factor V; FVIIIa; activated factor VIII; APC; activated PC; PROC; PC gene; VTE; venous thromboembolism; Se; secondary; Sp; spontaneous; UTRs; untranslated regions; SSCP; single-strand conformation polymorphism;
Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice
Keywords: عامل هسته ای هپاتوسیت; Berberine; Liver; Drug-drug interactions; AhR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; CYP; Cytochrome P450; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; HLM; human liver microsomes; HNF; hepatocyte nuclear factor; HPLC-M
Mass spectrometry-based plasma peptide profiling of acute exacerbation in HBeAg-positive chronic hepatitis B
Keywords: عامل هسته ای هپاتوسیت; AE; acute exacerbation; APOA4; apolipoprotein A-IV; APP; acute-phase proteins; CHB; chronic hepatitis B; CHC; chronic hepatitis C; FGA; fibrinogen α chain; FGB; fibrinogen β chain; HCCA; alpha-cyano-4-hydroxycinnamic acid; HNF; hepatocyte nuclear factor
Research ArticleDirected differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells
Keywords: عامل هسته ای هپاتوسیت; iPS; induced pluripotent stem; TGF; transforming growth factor; ES; embryonic stem; PS; primitive streak; ME; mesendoderm; DE; definitive endoderm; Afp; alpha-fetoprotein; FGF; fibroblast growth factor; Hnf; hepatocyte nuclear factor; Krt; keratin; FBS; f
Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells
Keywords: عامل هسته ای هپاتوسیت; Hepatic Cell Differentiation; Liver Development; Liver Regeneration; CEACAM; carcinoembryonic antigen-related cell adhesion molecule; CDE; choline-deficient ethionine-supplemented; CK19; cytokeratin 19; CPS1; carbamoyl-phosphate-synthetase 1; CreER; cyc
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARα)
Keywords: عامل هسته ای هپاتوسیت; ABC; ATP-binding cassette; ACC; Acetyl-Coenzyme A carboxylase; BADGE; Bayesian Analysis of Differential Gene Expression; CPT; Carnitine palmitoyltransferase; CT; CTP:phosphocholine cytidylyltransferase; DHA; docosahexaenoic acid; FAS; fatty acid synthase;
Commitment of stem cells into functional hepatocytes
Keywords: عامل هسته ای هپاتوسیت; Stem cells; ES; iPS; MSC; Hepatocyte; Differentiation; AT-MSCs; adipose-tissue-derived mesenchymal stem cells; BMP; bone morphogenetic protein; Dex; dexamethasone; EGF; epidermal growth factor; ES cells; embryonic stem cells; FGF; fibroblast growth factor
Influence of hepatocyte nuclear factor 4α (HNF4α) gene variants on the risk of type 2 diabetes: A meta-analysis in 49,577 individuals
Keywords: عامل هسته ای هپاتوسیت; Hepatocyte nuclear factor; HNF4α; Liver; Meta-analysis; Systematic review; Polymorphisms; Type 2 diabetes
CommentaryAngiotensin-converting enzyme 2 and new insights into the renin-angiotensin system
Keywords: عامل هسته ای هپاتوسیت; ACE; angiotensin-converting enzyme; ADAM; a disintegrin and metalloproteinase; Ang; angiotensin; ARDS; acute respiratory distress syndrome; AT1; angiotensin receptor, type 1; CoV; coronavirus; HEK; human embryonic kidney; HNF; hepatocyte nuclear factor; m
Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor γ complex and correlates with liver steatosis
Keywords: عامل هسته ای هپاتوسیت; ApoC-IV; apolipoprotein C-IV; PPAR; peroxisome proliferators-activated receptor; RXR; retinoid X receptor; VLDL; very low density lipoprotein; SEAP; secreted alkaline phosphatase; EMSA; electrophoretic mobility shift assay; ChIP; chromatin immunoprecipita
Pancreatic Beta-cell Apoptosis in Maturity Onset Diabetes of the Young
Keywords: عامل هسته ای هپاتوسیت; Glucokinase; hepatocyte nuclear factor; insulin secretion; metabolism; pancreatic duodenal homeobox 1gène pdx-1; facteur nucléaire hépatocyte; glucokinase; insulinosécrétion; métabolisme
Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors
Keywords: عامل هسته ای هپاتوسیت; W; Williams' medium E; KSFM; keratinocyte serum-free medium; Dex; dexamethasone; EGF or E; human epidermal growth factor; PGE or P; pituitary gland extract; C/EBP; CCAAT/enhancer-binding protein; HNF; hepatocyte nuclear factor; RXR; retinoid X receptor;
Hepatocyte nuclear factor-4α and -1 small interfering RNA inhibits hepatocyte differentiation induced by extracellular matrix
Keywords: عامل هسته ای هپاتوسیت; ECM; extracellular matrix; EHS; Engelbreth-Holm-Swarm; HNF; hepatocyte nuclear factor; RNAi; RNA interference; dsRNA; double-stranded RNA; siRNAs; small interfering RNAs; RISCs; RNA induced silecing complexes; DIG; digoxigenin; Collagen; Engelbreth-Holm-S
Disaccharide Digestion: Clinical and Molecular Aspects
Keywords: عامل هسته ای هپاتوسیت; CE; cis-element; HNF; hepatocyte nuclear factor; IBS; irritable bowel syndrome; LPH; lactase-phlorizin hydrolase; MGAM; maltase-glucoamylase; mRNA; messenger RNA; SI; sucrase isomaltase;
Neonatal hyperphenylalaninemia, perinatal hemochromatosis, and renal tubulopathy: A unique patient or a novel metabolic disorder?
Keywords: عامل هسته ای هپاتوسیت; Hyperphenylalaninemia; Phenylketonuria; Tetrahydrobiopterin; Phenylalanine hydroxylase; Perinatal hemochromatosis; Neonatal hemochromatosis; Renal tubulopathy; Fanconi syndrome; Hepatocyte nuclear factor; Dihydrofolate reductase;