Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; SCA21; spinocerebellar ataxia type 21; TMEM240; transmembrane protein 240; LAMP2A; lysosome-associated membrane protein 2a; TSG101; tumor susceptibility gene 101; Iba1; ionized calcium-binding adapter molecule 1; GFAP; glial fibrillary acidic protein; LC3
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Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; BSA; bovine serum albumin; CGRP; calcitonin gene-related peptide; DPA; dynamic plantar aesthesiometer; FPKM; fragments per kilobase of exon per million reads mapped; GFAP; glial fibrillary acidic protein; GO; gene ontology; i.p.; intraperitoneal; Iba1; io
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Microglia; Stress; Alzheimer's disease; Neurodegeneration; Neuroinflammation; Synaptic remodeling; Microglial phenotypes; Dark microglia; Aβ; Amyloid beta; ABCA7; ATP-binding cassette transporter A7; AD; Alzheimer's disease; APOE; Apolipoprotein E; APP;
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; RE; refractory epilepsy; NE; non-epileptic; C3; complement 3; IBA1; ionized calcium-binding adapter molecule 1; Trem2; triggering receptor expressed on myeloid cells 2; MerTK; Mer receptor tyrosine kinase; Pros1; Protein S; Map2; microtubule associated pr
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; TBI; traumatic brain injury; LY; Lucifer yellow; Iba1; ionized calcium-binding adapter molecule 1; GFAP; glial fibrillary acidic protein; Neuroinflammation; Microglia reactivity; Diffuse traumatic brain injury; Permeabilized neurons; Concussion;
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CD; cluster of differentiation; DALT; dense anodular lymphoid tissue; DC(s); Dendritic cell(s); DLT; diffuse lymphoid tissue; FFPE; formalin-fixed paraffin-embedded; Foxp3; forkhead box P3; GAM; goat anti-mouse Immunoglobulin G; GAR; goat anti-rabbit Immu
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Cilostazol; Enzymatically modified isoquercitrin; Reactive oxygen species; Colorectal cancer; Murine azoxymethane/dextran sodium sulphate-induced colorectal carcinoma model; AC; anthocyanin; ACF; aberrant crypt foci; ALA; α-lipoic acid; AOM; azoxymethane
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CD11b; cluster of differentiation molecule 11Bâ; CNS; central nervous system; COX2; cyclooxygenase-2; DN; diabetic neuropathy; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding adapter molecule 1; IENF; intra-epidermal nerve fiber; I
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CCI; controlled cortical impact; DPI; days post injury; GFAP; glial fibrillary acidic protein; HPI; hours post injury; IBA-1; ionized calcium-binding adapter molecule 1; MRI; magnetic resonance imaging; NOR; novel object recognition; PBS; phosphate-buffer
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ALS; amyotrophic lateral sclerosis; AR; androgen receptor; BDNF; brain-derived neurotrophic factor; CGRP; calcitonin gene-related peptide; ChAT; choline acetyltransferase; DAB; diaminobenzidine; DLN; dorsal nucleus; ENK; enkephalin; GFAP; glial fibrillary
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Proinsulin; Therapy; Adeno-associated virus vector; Cognitive loss; Inflammaging; A2M; α-2-macroglobulin; Aβ; amyloid β peptides; AβPP; amyloid β protein precursor; AAV; adeno-associated virus; AD; Alzheimer's disease; Akt; protein kinase B; ANOVA; a
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; 5-HT; serotonin; ACTH; adrenocorticotropic-hormone; AH/POA; anterior hypothalamic/preoptic area; AP; alkaline phosphatase; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; bpm; beats per minute; CBF; cerebral blood flow; CNS; central nervous system; COPD; chro
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Dw; diffusion weighted; MRI; magnetic resonance imaging; Iba1; Ionized Calcium-Binding Adapter Molecule 1; T2w; transverse relaxation time weighted; TIA; transient ischemic attack; Photothrombosis; Peri-infarct; Mild ischemic injury; Magnetic resonance im
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; 2-AG; 2-arachidonoyl-glycerol; AEA; anandamide; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; DOPAC; 3,4-Dihydroxyphenylacetic acid; DA; dopamine; D2; dopamine receptor subtype 2; ECS; endocannabinoid sys
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CA; cornu ammonis; DG; dentate gyrus; HC; hippocampus; IL-1 β; interleukin-1 beta; IL-6; interleukin-6; ISTD; internal standard solution; Iba1; ionized calcium-binding adapter molecule 1; KYN; Kynurenine; LC-MS/MS; Liquid Chromatography Mass Spectrometry
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; GD; Gestational day; PND; Postnatal day; i.p.; Intraperitoneal; PolyI:C; Polyinosinic-polycytidylic acid; NaCl; Sodium chloride; EH; Environmental enriched housing; SH; Standard housing; T; Treatment effect; H; Housing effect; TxH; Treatment Ã housing
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; VGKCs; voltage-gated potassium channels; MS; Multiple Sclerosis; NAWM; normal appearing white matter; CNS; central nervous system; BBB; blood-brain barrier; Nav; voltage-gated sodium channel; PN; paranode; JXP; juxtaparanode; Caspr; contactin-associated
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; cAMP; cyclic adenosine monophosphate; CGRP; calcitonin gene-related peptide; CRE; cAMP response element; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; MAPKs; mitogen-activated protein kinases; nAch; nicotinic ace
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; BrdU; bromodeoxyuridine; GCL; ganglion cell layer; Iba1; ionized calcium-binding adapter molecule 1; IPL; inner plexiform layer; MHC-II; histocompatibility complex class II; ON; optic nerve; OPL; outer plexiform layer; PBS; phosphate-buffered saline; RGC;
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; BMS; Basso Mouse Scale; BSA; bovine serum albumin; CBA; cytometric bead assay; CNS; central nervous system; dpi; day post injury; EAE; experimental autoimmune encephalomyelitis; FBS; fetal bovine serum; FoxP3; forkhead box P3; GFAP; glial fibrillary acidi
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; histiocytic disorder; immunohistochemistry; ionized calcium-binding adapter molecule 1; monocyte/macrophage
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; AGEs; advanced end glycation products; ANOVA; analysis of variance; AO; anti-oxidative; BP; blood pressure; CV; cresyl violet; DBP; diastolic blood pressure; h; hour; Iba-1; ionized calcium-binding adapter molecule 1; IR; ischemic-reperfusion; MCA; middle
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; AC; adenylyl cyclase; ACI rat; August Copenhagen Irish rat; ADRB2; β2-adrenergic receptor; AP; action potential; BKCa; large conductance Ca2 +-activated K+ channel; BSA; bovine serum albumin; cDNA; complementary DNA; Cy2/Cy3; cyanine dyes; dLGN; dorsal
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Gases; Neuroprotective effect; Mechanism; Clinical translation; Research perspectives; AD; Alzheimer's disease; AMPA; alpha-amino-d-hydroxy-5-methyl-4-isoxazole-propionate; Ar; argon; ATA; absolute atmosphere; ATP; adenosine triphosphate; BBB; blood-bra
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; IBA-1; ionized calcium-binding adapter molecule 1; TNF-α; tumor necrosis factor-alpha; IL-1β; interleukin beta 1; IL-6; interleukin 6; IL-10; interleukin 10; IFN-γ; interferon gamma; iNOS; inducible nitric oxide synthase; HO-1; heme oxygenase; ROS; rea
Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; PND; Postoperative neurocognitive disorder; BBB; blood-brain barrier; NK-1R; neurokinin-1 receptor; CNS; central nervous system; SP; substance P; NK-1Ra; neurokinin-1 receptor antagonist; PBS; phosphate-buffered saline; ELISA; enzyme-linked immunosorbent
The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Bax; Bcl-2 associated x protein; Bcl-2; B-cell lymphoma-2; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; CREB; cAMP-response element binding protein; GFAP; glial fibrillary acidic protein; H&E; haematoxylin and eosin; Iba-1; ionized c
Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle
A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; aCSF; artificial cerebrospinal fluid; CCI; chronic constriction injury; CGRP; calcitonin gene-related peptide; Cy3; indocarbocyanine; ERK; extracellular signal-regulated kinase; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; Iba1; ionized calci
Identification of a fatty acid binding protein4-UCP2 axis regulating microglial mediated neuroinflammation
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; FABP; Fatty acid binding protein; UCP2; uncoupling protein 2; PA; palmitic acid; ROS; reactive oxygen species; iNOS; inducible nitric oxide synthase; TNF-α; tumor necrosis factor alpha; Iba1; ionized calcium-binding adapter molecule 1; SFA; saturated fat
Potential role of CXCL10/CXCR3 signaling in the development of morphine tolerance in periaqueductal gray
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CaMKII; Ca2Â +/calmodulin dependent protein kinase II; CREB; cAMP response element binding protein; CXCL9; C-X-C motif chemokine 9; CXCL10; C-X-C motif chemokine 10; CXCL11; C-X-C motif chemokine 11; CXCR3; C-X-C motif chemokine receptor 3; rmCXCL10; reco
Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1G93A mouse model of amyotrophic lateral sclerosis
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; GAD; glutamic acid decarboxylase; GLT-1; glial glutamate transporter-1; Iba1; ionized calcium-binding adapter molecule 1; ND; numerical density; PB; phosphate buffer; PBS; phosphate-buffered
The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Cg; congenic; DMT1; divalent metal transporter 1; GFAP; glial fibrillary acidic protein; iba-1; ionized calcium-binding adapter molecule 1; LAMP1; lysosomal-associated membrane protein-1; Nramp1; natural resistance-associated macrophage protein-1; PD; Par
Microglia density decreases in the rat rostral nucleus of the solitary tract across development and increases in an age-dependent manner following denervation
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ANOVA; analysis of variance; CD68; cluster of differentiation 68; CNS; central nervous system; CT; chorda tympani nerve; CTX; chorda tympani nerve transection; Iba1; ionized calcium-binding adapter molecule 1; NTS; nucleus of the solitary tract; P#; postn
Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Apoptosis; Autophagy; Microglia; Traumatic brain injury; 3-MA; 3-Methyladenine; Iba-1; Ionized calcium-binding adapter molecule 1; ICV; Intracerebroventricular; IL-1β; Interleukin-1β; LC3; Protein light chain 3; mTOR; Mammalian target of rapamycin; PBS;
Involvement of progranulin in modulating neuroinflammatory responses but not neurogenesis in the hippocampus of aged mice
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ANOVA; Analysis of variance; Ctsz; cathepsin Z; DCX; doublecortin; DG; dentate gyrus; HPRT; hypoxanthine phosphoribosyltransferase; HSD; Honestly significant difference; Iba-1; ionized calcium-binding adapter molecule 1; IL-1β; interleukin-1β; IL-6; int
Impaired microglia fractalkine signaling affects stress reaction and coping style in mice
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ACTH; adrenocorticotropic hormone; CNS; central nervous system; CORT; corticosterone; CRH; corticotropin-releasing hormone; CVS; chronic variable stress; CX3CL1; fractalkine; CX3CR1; fractalkine receptor; CX3CR1â/â; fractalkine receptor deficient mice
LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; AD; Alzheimer's disease; BBB; blood brain barrier; Aβ; Amyloid beta; LRP1; low-density lipoprotein related protein 1; LXR; liver X receptor; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; GW3965; Alzheimer's
A new model of nerve injury in the rat reveals a role of Regulator of G protein Signaling 4 in tactile hypersensitivity
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; CB1 receptor; cannabinoid type-1 receptor; DRG; dorsal root ganglion; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; MPE; maximum-possible-effect; mSNI; modified spared nerve injury; PWT; paw withdrawal threshold;
Translational research for Parkinson׳s disease: The value of pre-clinical primate models
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; PD; Parkinson׳s disease; SNpc; substantia nigra pars compacta; L-DOPA; Levodopa, 3,4-dihydroxyphenylalanine; 6OHDA; 6-hydroxydopamine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AADC; L-aromatic amino acid decarboxylase; TH; tyrosine hydroxylase
Aging and a long-term diabetes mellitus increase expression of 1 α-hydroxylase and vitamin D receptors in the rat liver
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; DM; diabetes mellitus; VDR; vitamin D receptor; 1α-OHase; 1 α-hydroxylase; DM1; diabetes mellitus type 1; RXR; retinoid X receptors; STZ; streptozotocin; DAPI; 4â²,6-diamidino-2-phenylindole; PBS; phosphate buffer saline; SD; standard deviation; GFAP;
The anti-inflammatory peptide stearyl-norleucine-VIP delays disease onset and extends survival in a rat model of inherited amyotrophic lateral sclerosis
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ALS; amyotrophic lateral sclerosis; SOD1; superoxide dismutase 1; VIP; vasoactive intestinal peptide; PACAP; pituitary adenylate cyclase-activating polypeptide; SNV; stearyl-norleucine-VIP; PBS; phosphate-buffered saline; GFAP; glial fibrillary acidic pro
Research ReportGlio-vascular changes during ageing in wild-type and Alzheimer׳s disease-like APP/PS1 mice
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Aβ; amyloid-β; AD; Alzheimer׳s disease; APP; amyloid precursor protein; BBB; blood-brain barrier; CD31; cluster of differentiation 31; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding adapter molecule 1; PDGFR-β; platelet-derived
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; Blood-brain barrier; BBB; CSF; cerebrospinal fluid; CysLT1R; cysteinyl leukotriene receptor 1; CysLT2R; cysteinyl leukotriene receptor 2; CysLTs; cysteinyl leukotrienes; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic protein; Iba-1; ionized cal
The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; ALS; Amyotrophic Lateral Sclerosis; APAF1; Apoptotic protease activating factor 1; BH3-only protein; Bcl-2 homology domain 3-only protein; bid; BH3 interacting domain death agonist; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding ada
The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; GluK; kainate receptor; PGE2; prostaglandin E2; PGF2α; prostaglandin F2α; EP1; prostaglandin E2 receptor 1; EP2; prostaglandin E2 receptor 2; EP1-KO; prostaglandin E2 receptor 1 knockout mice; WT; C57Bl/6 wildtype mice; EC50; half maximal effective conc
Strain-dependent brain defects in mouse models of primary ciliary dyskinesia with mutations in Pcdp1 and Spef2
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; 129; 129S6/SvEvTac; B6; C57BL/6J; bgh; big giant head; CSF; cerebrospinal fluid; GFAP; glial fibrillary acidic protein; H&E; Hematoxylin and Eosin; Iba1; ionized calcium-binding adapter molecule 1; L1CAM; L1 cell adhesion molecule; MAP2; microtubule-assoc
Effects of chemokine (C-C motif) ligand 1 on microglial function
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; BDNF; brain-derived neurotrophic factor; bp; base pair; CCL-1; chemokine (C-C motif) ligand 1; CCL-2; chemokine (C-C motif) ligand 2; CCL-21; chemokine (C-C motif) ligand 21; CCR-8; chemokine (C-C motif) receptor 8; cDNA; complementary DNA; CNS; c
Increased expression of interleukin-18 in the trigeminal spinal subnucleus caudalis after inferior alveolar nerve injury in the rat
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; IL-18; interleukin-18; Vc; trigeminal spinal subnucleus caudalis; IANT; inferior alveolar nerve transection; DH; dorsal horn; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor-α; IAN; inferior alveolar nerve; Iba1; ionized calcium-binding adapter mo
Focal cerebral ischemia/reperfusion injury in mice induces hematopoietic prostaglandin D synthase in microglia and macrophages
Keywords: ملکول آداپتور اتصال دهنده کلسیم یونیزه 1; PGD2; PGDS; microglia/macrophage; inflammation; ischemic stroke; tissue repair; COX; cyclooxygenase; EGFP; enhanced green fluorescent protein; GFAP; glial fibrillary acidic protein; GST-Ï; glutathione S-transferase-pi; H-PGDS; hematopoietic prostaglandin