Keywords: Tau PET; Off-target; AV-1451; THK5351; THK5117; THK5317; T807; MAO-B; MAO-A; Flortaucipir;
مقالات ISI (ترجمه نشده)
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Keywords: MAO-B; Serotonin; Suicide; Violence; Early life adversity;
Keywords: ACC; anterior cingulate cortex; DEM; diethyl maleate; DEX; dexamethasone; GR; glucocorticoid receptor; MAO-A; monoamine oxidase A; MAO-B; monoamine oxidase B; MDD; major depressive disorder; MDE; major depressive episode; PFC; prefrontal cortex; Monoamine
Keywords: Dopamine; Ecstasy; Methamphetamine; METH; 3,4-Methylenedioxymethamphetamine; MDMA; Mouse; Neurodegeneration; Neuroinflammation neurotoxicity; Non-human primate; Rat; AC; adenylyl cyclase; AcbSh; nucleus accumbens shell; AcbC; nucleus accumbens core; cAMP;
Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
Keywords: PCa; prostate cancer; OR; odds ratio; MAO-B; monoamine oxidase isoenzyme type B; TNM; tumour, node, metastasis; ICD; International classifications of diseases; CCI; Charlson comorbidity index; Case-control study; Epidemiology; Odds ratio; Parkinson's di
Keywords: ADL; activities of daily living; COMT; catechol-O-methyltransferase; DOI; 2,5-dimethoxy-4-iodoamphetamine; GIRK; G-protein-gated inwardly rectifying potassium; GP; globus pallidus; GPCR; G protein-coupled receptor; GPe; external segment of GP; GPi; intern
Keywords: AMT; α-methyl-l-tryptophan; BBB; blood-brain barrier; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; FLAIR; fluid-attenuated inversion recovery; Gd-DTPA; gadolinium-diethylenetriaminepentacetate; GFAP;
Keywords: Phthalide; 2-Benzofuran-1(3H)-one; Monoamine oxidase; MAO-B; Reversible inhibition; Structure-activity relationship;
Keywords: AMPK; AMP-activated protein kinase; CamKKβ; calmodulin-dependent kinase kinase β (CamKKβ); DARPP-32; dopamine-and cAMP-regulated phosphoprotein of Mr 32 kDa; ERK; extracellular signal-regulated kinase; HDACs; histone deacetylases; MAO-A; monoamine oxi
Keywords: 5-HT; serotonin; 5-HTT; serotonin transporter; AMPH; d-amphetamine; ANOVA; analysis of variance; CCD; charge coupled device; COMT; catechol-O-methyltransferase; DA; dopamine; DAT; dopamine transporter; EDTA; ethylenediaminetetraacetic acid; GFAP; glial fi
Keywords: SNc; substantia nigra pars compacta; PD; Parkinson disease; NMS; nonmotor symptoms; MAO-B; monoamine oxidase-B; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxy dopamine; GBA; glucocerebrosidase; STN
Keywords: Aβ; amyloid β; AADC; L-amino acid decarboxylase; ACC; Anterior cingulate cortex; AD; Alzheimer's disease; aMCI; Amnestic mild cognitive impairment; APP; Amyloid precursor protein; AR; Adrenergic receptor; ATMX; atomoxetine; BDNF; Brain-derived neurotrop
Interactions of endocannabinoid virodhamine and related analogs with human monoamine oxidase-A and -B
Keywords: Anandamide (PubChem CID: 5281969); 2-Arachidonoylglycerol (PubChem CID: 5282280); Clorgyline (PubChem CID: 28767); Dimethyl sulfoxide (PubChem CID: 679); R-(â)-Deprenyl hydrochloride (PubChem CID: 5195); 4-Hydroxyquinoline (PubChem CID: 69141); Kynurami
Discovery of potent and reversible MAO-B inhibitors as furanochalcones
Keywords: Furanochalcone; MAO-B; Reversible and competitive inhibitor; Potent; Molecular docking;
GABA function may be related to the impairment of learning and memory caused by systemic prenatal hypoxia-ischemia
Keywords: BSA; bovine serum albumin; CA; Ammon's horn; DG; dentate gyrus; EAAT; excitatory amino acid transporter; GABA; γ-aminobutyric acid; GAD; glutamic acid decarboxylase; HI; hypoxia-ischemia; HIE; hypoxic-ischemic encephalopathy; HRP; horseradish peroxidas
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
Keywords: Antidepressant; Bioassay-guided fractionation; HR-ESI-MS; Molecular docking; Monoamine oxidase; NMR; BuOH; n-Butanol; CC; Chromatographic column; CH2CL2; Dichloromethane; CHCl3; Chloroform; EtOAc; Ethyl acetate; EtOH; Ethanol; FAD; Flavin adenine dinucleo
Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22â¯cells
Keywords: ER stress; Ferroptosis; Oxidative stress; Oxindole; Oxytosis; Rasagiline; ATF6; activated transcription factor 6; ARE; antioxidant response element; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; Grp78; 78-kDa glucose-regulated prote
Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease
Keywords: AD; Alzheimer's disease; AChEIs; acetylcholinesterase inhibitors; NMDA; N-methyl-d-aspartate; Aβ; β-amyloid; Ï; tau protein; ACh; acetylcholine; MTDLs; multi-target-directed ligands; MAO-B; monoamine oxidase B; MAO-A; monoamine oxidase A; BuChE; buty
A silk peptide fraction restores cognitive function in AF64A-induced Alzheimer disease model rats by increasing expression of choline acetyltransferase gene
Keywords: ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer disease; BF-7; brain factor-7; ChAT; choline acetyltransferase; CNS; central nervous system; CSF; cerebrospinal fluid; F3.ChAT; neural stem cell encoding ChAT gene; GFAP; glial fibrillary acidi
Impairment in the mesohippocampal dopamine circuit following exposure to the brominated flame retardant, HBCDD
Keywords: Asyn; alpha-synuclein; BFR; brominated flame retardants; COMT; catechol-O-methyltransferase; DAB; 3,3â²-diaminobenzidine; DAT; dopamine transporter; HBCDD; hexabromocyclododecane; MAO-B; monoamine oxidase-B; NET; norepinephrine transporter; PBDE; polybro
Emotional disorders induced by Hemopressin and RVD-hemopressin(α) administration in rats
Keywords: CB1; cannabinoid 1; COMT; catechol O-methyltransferase; DA; dopamine; eCB; encocannabinoid; Hp; hemopressin; 5-HT; serotonin; MAO-B; monoamine oxidase-B; NE; norepinephrine; RVD-hp(α); RVD-hemopressin(α); TRPV1; Transient Receptor Potential Vanilloid Ty
Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease
Keywords: Alzheimer's disease; Coumarin; Donepezil; MAO-B; Cholinesterase; Molecular modeling;
Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors
Keywords: Coumarin; Pyridazine; MAO-B; Neurodegenerative disorders; Molecular modeling; ADME;
Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain
Keywords: TD; thiamine deficiency; MDA; malondialdehyde; NO; nitric oxide; Aβ1-42; β-amyloid peptide 1-42; Aβ1-40; β-amyloid peptide 1-40; Glu; glutamic acid; ACh; acetylcholine; AChE; acetylcholinesterase; ChAT; choline acetyltransferase; MAO-B; monoam
MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains
Keywords: MAO-A; MAO-B; Amplex red; Benzimidazole; Propargyl; Hydrazone; Docking;
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold
Keywords: 2,3-Dihydro-1,3,4-oxadiazoles; Neurodegenerative disorders; MAO-B; Docking; Molecular dynamics;
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation
Keywords: MAO-A; MAO-B; Human acetylcholinesterase; Human butyrylcholinesterase; Molecular modeling; Molecular docking; Alzheimer's disease; Metal chelating properties; Antioxidant properties; ADME+T properties;
Radiosynthesis and ex vivo evaluation of [18F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET
Keywords: Positron emission tomography; Fluorine-18; SL25.1188; MAO-B;
Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies
Keywords: Methoxylated chalcone; MAO-A; MAO-B; Molecular docking
Inhibitive activities detection of monoamine oxidases (MAO) A and B inhibitors in human liver MAO incubations by UPLC-ESI-MS/MS
Keywords: MAO-A; MAO-B; 5-HIAA; PAA; Inhibitor; UPLC-ESI MS/MS;
Synthesis and evaluation of isatin-β-thiosemicarbazones as novel agents against antibiotic-resistant Gram-positive bacterial species
Keywords: Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant Enterococcus; Isatin-β-thiosemicarbazone; In vitro activity; Structure-activity relationships; MRSA; methicillin-resistant Staphylococcus aureus; VRE; vancomycin-resistant Enterococcus;
The effect of CA1 dopaminergic system in harmaline-induced amnesia
Keywords: ANOVA; analysis of variance; LTP; long-term potentiation; MAO-A; monoamine oxidase-A; MAO-B; monoamine oxidase-B; harmaline; dopamine; step-down; CA1; passive avoidance memory;
Association of Catechol-O-Methyltransferase and monoamine oxidase B gene polymorphisms with motor complications in parkinson's disease in a Chinese population
Keywords: Parkinson's disease; COMT; MAO-B; Wearing-off; Dyskinesias;
Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer’s disease
Keywords: MAO-B; Alzheimer’s disease; PET; Pyrazoline derivatives; Molecular imaging
Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes
Keywords: MAO-B; monoamine oxidase type B; COMT; catechol-o-methyltransferase; DRD4; dopamine receptor D4; DAT; dopamine transporter; DBH; dopamine beta-hydroxylase; SNP; single nucleotide polymorphism; VNTR; variable number of tandem repeats; Alcohol dependence; A
Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release
Keywords: Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c
Selected furanochalcones as inhibitors of monoamine oxidase
Keywords: Chalcone; Monoamine oxidase; MAO-B; Reversible inhibition; Competitive;
The antinociceptive effect of reversible monoamine oxidase-A inhibitors in a mouse neuropathic pain model
Keywords: ANOVA; analysis of variance; CCI; chronic constriction injury; 2-DMPI; 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole; GABA; γ-amino butyric acid; 4-HQ; 4-hydroxyquinoline; 5-HT; 5-hydroxytryptamine; ID50; 50% inhibitory dose; Imax; maximum inhibition
Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson's disease
Keywords: Monoamine oxidase B; MAO-B; Parkinson's disease; Oxazolopyridine; Thiazolopyridine;
Identification and validation of platelet low biological variation proteins, superior to GAPDH, actin and tubulin, as tools in clinical proteomics
Keywords: 1-D WB; one-dimensional Western blot; 2-D DIGE; two-dimensional difference gel electrophoresis; DTT; dithiothreitol; GADPH; Glyceraldehyde 3-phosphate dehydrogenase; LC; loading control; LBVP; low biological variation protein; Mao-B; monoamine oxidase B;
The adenosine A2A antagonistic properties of selected C8-substituted xanthines
Keywords: Adenosine A2A receptors; Antagonism; Xanthine; Haloperidol-induced catalepsy; Parkinson's disease; CNS; central nervous system; CPA; cyclopentyladenosine; CSC; (E)-8-(3-chlorostyryl)caffeine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDAC; N
Selected chromone derivatives as inhibitors of monoamine oxidase
Keywords: Chromone; Benzopyran-4-one; Monoamine oxidase; MAO-B; Reversible inhibition; Structure-activity relationships;
Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues
Keywords: Piperamides; Antidepressant; Antioxidant; MAO-A; MAO-B;
Research ReportModulations of brain amines and dopaminergic behavior by a novel, reversible and selective MAO-B inhibitor
Keywords: MAO-B; monoamine oxidase B; NP-9; 3-(anthracen-10-yl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazole; DA; dopamine; NA; noradrenaline; 5-HT; serotonin; DOPAC; dihydroxyphenylacetic acid; HIAA; 5-hydroxyindole acetic acid; MAP; mean arterial pressure; PEA; phen
Signal transduction pathway activity compensates dopamine D2/D3 receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [3H]raclopride and [35S]GTPγS
Keywords: ARG; autoradiography; DAT; dopamine transporter; GTPγS; guanosine 5â²-O-[gamma-thio]triphosphate; l-DOPA; L-3,4-dihydroxyphenylalanine; MAO-B; Monoamine oxidase B; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; OD; optical density; PD; Parkinson's
Anxiety in Parkinson's disease: A critical review of experimental and clinical studies
Keywords: Parkinson's disease; Anxiety; Clinical studies; Animal models; Review; BLA; basolateral nucleus of the amygdala; BDZs; benzodiazepines; CNS; central nervous system; DSM; Diagnostic and Statistical Manual of Mental Disorders; DA; dopamine; DOPAC; 3,4-dih
Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine
Keywords: Indoles; Naphthyridines; Multipotent molecules; EeAChE; eqBuChE; MAO-A; MAO-B; Kinetic analysis; Inhibition mechanism; Molecular modeling; Amyloid β; Alzheimer's disease
Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients
Keywords: Mao-B; Alzheimer's disease; Dementia; Parkinson's disease; Ageing; Platelets proteomics