دانلود مقالات ISI درباره Mglur + ترجمه فارسی

The increased expression of metabotropic glutamate receptor 5 in subventricular zone neural progenitor cells and enhanced neurogenesis in a rat model of intracerebral hemorrhage

Keywords: mGluR5; CHPG; intracerebral hemorrhage; neurogenesis; rat; BDNF; brain derived neurophic factor; bFGF; basic fibroblast growth factor; BMSCs; bone marrow derived stroma cells; BrdU; 5-bromo-2′-deoxyuridine; CHPG; (R,S)-2-chloro-5-hydroxyphenylglycine; C

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting glutamate system for novel antipsychotic approaches: Relevance for residual psychotic symptoms and treatment resistant schizophrenia

Keywords: Psychosis; Glycine; Sarcosine; AMPAkine; mGluR; Memantine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Membrane-initiated estradiol actions mediate structural plasticity and reproduction

Keywords: Estradiol receptor; mGluR; Caveolin; Spinogenesis; Lordosis behavior; Dendritic spines

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Cellular and Molecular NeuroscienceResearch PaperGlutamatergic input-output properties of thalamic astrocytes

Keywords: astrocytes; glutamate; SIC; gliotransmission; somatosensory; tripartite synapse; CT; corticothalamic; GT; gliotransmission; Lem; Lemniscal; mGluR; metabotropic glutamate receptor; NMDA-R; N-methyl-d-aspartate receptor; PSC; post synaptic current; SIC; slo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The effects of metabotropic glutamate receptor 7 allosteric agonist N,N′-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase si

Keywords: mGluRs; sevoflurane; neurotoxicity; MAPK; learning and memory; hippocampus; AMN082; N,N′-dibenzhydrylethane-1,2-diamine dihydrochloride; EDTA; ethylenediaminetetraacetic acid; ERK1/2; extracellular signal-regulated kinase 1 and 2; FCM; Flow cytometry; H

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake

Keywords: Excitotoxicity; Motoneurons; Fictive locomotion; 5-HT; 5-hydroxytryptamine; ANOVA; analysis of variance; CCF; cross correlation factor; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CV; coefficient of period variation; DAPI; 4′,6-diamidino-2-phenylindole;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Ca2+-dependent binding of calcium-binding protein 1 to presynaptic group III metabotropic glutamate receptors and blockage by phosphorylation of the receptors

Keywords: mGluR; metabotropic glutamate receptor; CaM; calmodulin; CaBP1; calcium-binding protein 1; VILIP-2; visinin-like protein-2; NCS-1; neuronal calcium sensor-1; PKC; protein kinase C; ct; intracellular C-terminal tail; NA-HRP; horseradish peroxidase-conjugat

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and SAR of centrally active mGlu5 positive allosteric modulators based on an aryl acetylenic bicyclic lactam scaffold

Keywords: mGluR; Potentiator; Positive allosteric modulator; Schizophrenia; Hyperlocomotion

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Estrogen receptors stimulate brain region specific metabotropic glutamate receptors to rapidly initiate signal transduction pathways

Keywords: ER, estrogen receptor; mER, membrane-associated estrogen receptor; mGluR, metabotropic glutamate receptor; pCREB, cAMP response element binding proteinEstradiol; mGluR; Hypothalamus; Arcuate Nucleus; Caveolin; Hippocampus; Striatum

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Positive allosteric modulation of metabotropic glutamate receptor 5 down-regulates fibrinogen-activated microglia providing neuronal protection

Keywords: BBB; blood brain barrier; CDPPB; 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide; CGC; cerebellar granule cells; CNS; central nervous system; DCGIV; (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine; ERK1/2; extracellular signal-regulated kinas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Galantamine rescues lead-impaired synaptic plasticity in rat dentate gyrus

Keywords: LTP; long-term potentiation; LTD; long-term depression; DP; depotentiation; DG; dentate gyrus; NMDA; N-methyl-d-aspartate; NO; nitric oxide; LFS; low frequency stimulus; PPF; paired-pulse facilitation; NOS; NO synthase; PKC; protein kinase; NF-κB; nuclea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Glutamatergic drive of the dorsal raphe nucleus

Keywords: Serotonin; Vesicular glutamate transporter; Neurokinin 1; Substance P; AMPA; Kainate; mGluR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Transient receptor potential vanilloid 1 agonists modulate hippocampal CA1 LTP via the GABAergic system

Keywords: TRPV1; Long-term potentiation; Long-term depression; Capsaicin; mGluR; HippocampusLTD, long-term depression; LTP, long-term potentiation; NMDA, N-methyl-d-aspartate; DHPG, (RS)-3,5-Dihydroxyphenylglycine; fEPSP, field excitatory postsynaptic potential; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

6-Aryl-3-pyrrolidinylpyridines as mGlu5 receptor negative allosteric modulators

Keywords: mGlu5 NAM; Metabotropic glutamate receptors; GPCR; mGluR; CNS drug discovery

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Distinct mechanisms contribute to agonist and synaptically induced metabotropic glutamate receptor long-term depression

Keywords: CA1; Hippocampus; LTD; mGluR; Plasticity; N-Type calcium channel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Metabotropic glutamate receptor 5 promotes proliferation of human neural stem/progenitor cells with activation of mitogen-activated protein kinases signaling pathway in vitro

Keywords: neural stem/progenitor cells; proliferation; metabotropic glutamate receptors; mitogen-activated protein kinases; cyclin D1; bFGF; basic fibroblast growth factor; CNS; central nervous system; DHPG; (S)-3,5-dihydroxyphenylglycine hydrate; DMEM/F12; Dulbecc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Microarray analysis of gene expression changes in the brains of NR2B-induced memory-enhanced mice

Keywords: NR2B transgenic mice; microarray; gene expression profile; RyR; Homer-1c; AD; Alzheimer's diseases; CNS; central nervous system; CREB; cAMP response element-binding protein; ER; endoplasmic reticulum; FDR; false discovery rate; GAPDH; glyceraldehyde-3-pho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of theta-frequency oscillations in the rat medial septal diagonal band slice by metabotropic glutamate receptor agonists

Keywords: metabotropic glutamate receptors; septal region; theta oscillation; ACPD; (1S, 3R)-1-aminocyclopentane-1,3-dicarboxylic acid; ACSF; artificial cerebrospinal fluid; ChAT; choline acetyltransferase; CPCCOEt; 7-(hydroxyimino) cyclopropa[b]chromen-1a-carboxyl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Activation of the sigma receptor 1 suppresses NMDA responses in rat retinal ganglion cells

Keywords: σR1; NMDA receptor; neurotransmission; retina; ganglion cells; G protein; [Ca2+]i; intracellular Ca2+ concentration; DAG; diacylglycerol; DMSO; dimethyl sulfoxide; GC; ganglion cell; IP3; inositol-1,4,5-triphosphate; IPL; inner plexiform layer; mGluR; me

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate

Keywords: inflammation; lipopolysaccharide; microglia; APDC; (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate; BAPTA-AM; 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester); chelerythrine chloride; 1,2-dimethoxy-N-methyl(1,3)benzo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Total oligomeric flavonoids of Cyperus rotundus ameliorates neurological deficits, excitotoxicity and behavioral alterations induced by cerebral ischemic-reperfusion injury in rats

Keywords: AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; ANSA; amino napthol sulphonic acid; ATP; adenosine triphosphates; BHT; butylated hydroxyl toluene; CA; cornu ammonis; CR; Cyperus rotundus; DNPH; dinitrophenyl hydrazine; DTNB; 2,4-dithionitrobenz

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Glycerophospholipids and glycerophospholipid-derived lipid mediators: A complex meshwork in Alzheimer's disease pathology

Keywords: 2-AG; 2-arachidonoylglycerol; 4-HNE; 4-hydroxynonenals; 4-HHE; 4-hydroxyhexenal; AA; arachidonic acid; Aβ; β-amyloid; ADAM; A Disintegrin And Metalloprotease; ADAPT; Alzheimer's Disease Anti-inflammatory Prevention trial; AD; Alzheimer's disease; AE

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

The identification of novel orally active mGluR5 antagonist GSK2210875

Keywords: mGluR; mGluR5; Brain free fraction; Negative allosteric modulator; Allosteric modulator; GPCR; Family C GPCR; Metabotropic glutamate receptor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2

Keywords: Metabotropic glutamate receptor ligand; Metabotropic glutamate receptor; Positive allosteric modulator; mGluR; mGlu; mGluR2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus

Keywords: Spontaneously epileptic rat; Epilepsy; EAATs; mGluR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear

Keywords: 3V; 3rd ventricle; BLA; basolateral nucleus of the amygdala; CC; cingulate cortex; CeA; central nucleus of the amygdala; CPu; caudate putamen; CPS; composite pain score; DG; dentate Gyrus; DMSO; dimethylsulfoxide; dPAG; dorsal PAG; FC; fear conditioning;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-d-asparate-type glutamate receptors

Keywords: glutamate; calcium; head injury; amino acid; spermidine; AMPAr; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor; ANOVA; analysis of variance; APV; dl-2-Amino-5-phosphonopentanoic acid; BDNF; brain derived neurotrophic factor; CA; cornu ammo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

Keywords: Dopamine replacement; Motor complication; Rotarod; Rotation; AIMs; Involuntary movements; Dopamine denervation; mGluR; Glutamate receptor; Neurotransmitter; Striatum; LID;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

P2Y1 receptors inhibit long-term depression in the prefrontal cortex

Keywords: Synaptic plasticity; Prefrontal cortex; ATP; P2Y receptor; mGluR; Voltage-sensitive calcium channels

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmission in the cerebellar cortex

Keywords: 2-arachidonoylglycerol; CB1 cannabinoid receptor; endocannabinoid; retrograde signaling; synaptic plasticity; voltage-gated calcium channels; ACSF; artificial cerebrospinal fluid; DMSO; dimethylsulfoxide; DNQX; 6,7-dinitroquinoxaline-2,3-dione; DSE; depol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Suppression of spontaneous firing in inferior colliculus neurons during sound processing

Keywords: IPSP; intracellular recording; signal-to-noise ratio; awake animal; bat; frequency modulated sweep; CL; confidence limit; FM; frequency modulated; IC; inferior colliculus; mGluR; metabotropic glutamate receptor; PSTH; peristimulus time histogram;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Clinical utility of calcimimetics targeting the extracellular calcium-sensing receptor (CaSR)

Keywords: CaSR; calcium-sensing receptor; Cao2+; extracellular calcium concentration; PTH; parathyroid hormone; NKF; National Kidney Foundation; FDA; US Food and Drug Administration; CKD; chronic kidney disease; MGluR; metabotropic glutamate receptor; GABA; gamma a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Glutamatergic synaptic transmission in neuroendocrine cells: Basic principles and mechanisms of plasticity

Keywords: Magnocellular; Paraventricular; Supraoptic; Vasopressin; Oxytocin; Glutamate; Retrograde; Metaplasticity; mGluR; Astrocyte

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Fragile X: Leading the Way for Targeted Treatments in Autism

Keywords: Fragile X syndrome; autism; ASD; mGluR; GABA; treatment; animal model;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system

Keywords: postsynaptic density; peripheral nervous system; motor endplate; superior cervical ganglion; myenteric ganglion; intraganglionic laminar endings; ANS; autonomic nervous system; AZ; active zone; BT; α-bungarotoxin; DAB; diaminobenzidine; ENS; enteric nerv

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation

Keywords: CB1 receptor; mechanically dissociated neuron; patch-clamp recording; retrograde signaling; spontaneous inhibitory postsynaptic currents; CB1; cannabinoid type 1; DAG; diacylglycerol; DHPG; (RS)-3, 5-dihydroxyphenylglycine; DSI; depolarization-induced sup

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway

Keywords: NTFs; neurotrophic factors; BDNF; brain-derived neurotrophic factor; GDNF; glial cell line-derived neurotrophic factor; NGF; nerve growth factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; iGluR; ionotropic glutamate receptor; mGluR; me

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Metabotropic glutamate receptors 1 and 5 differentially regulate bulbar dopaminergic cell function

Keywords: Olfactory bulb; Dopaminergic neuron; Glutamate; mGluR; mGluR5; Patch-clampt-ACPD, 1-aminocyclopentane-trans-1,3-dicarboxylic acid; AP5, d-2-amino-5-phosphonopentanoic acid; BAPTA, 1,2-bis-(2-aminophenoxy)-N,N,N′,N′-tetra acetic acid; BMI, bicuculline meth

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of brain aquaporins

Keywords: ANP; atrial natriuretic peptide; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; BSE; bovine spongiform encephalopathy; CaMKII; calcium/calmodulin dependent protein kinase II; cAMP; cyclic adenosine monophosphate; cGMP; cyclic gua

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2010 سفارش ترجمه

Membrane estrogen receptors activate metabotropic glutamate receptors to influence nervous system physiology

Keywords: Estradiol; MGluR; Lordosis; Nociception; Membrane; Rapid actions;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Habituation in Aplysia: The Cheshire Cat of neurobiology

Keywords: Homosynaptic depression; Long-term depression; Short-term memory; Long-term memory; AMPA receptor; NMDA receptor; mGluR; Protein phosphatase; Protein synthesis; Gene expression

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Glutamate-mediated calcium signaling: A potential target for lithium action

Keywords: mood stabilizers; NMDA; mGluR; hippocampus; rat[Ca2+]i, intracellular calcium; CPA, cyclopiazonic acid; DHPG, 3,5-dihydroxyphenylglycol; DMEM, Dulbecco's modified Eagle's medium; ER, endoplasmic reticulum; FBS, fetal bovine serum; GPCRs, G protein–coupled

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function

Keywords: mGluR; Pain; APDC; LY341495; Capsaicin; Primary afferent; Sensitization

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-α-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats

Keywords: umami; glycine; l-serine; l-arginine; condition taste aversion; taste transduction; AP5; d(-)-2-amino-5-phosphonophenylglycine; CPPG; (RS)-α-cyclopropyl-4-phosphonophenylglycine; CS; conditioned stimulus; CTA; conditioned taste aversion; GMP; guanosine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential

Keywords: GSK3; Fragile X; Lithium; mGluR; Behavior; Audiogenic seizures

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

The slow Ca2+-dependent K+-current facilitates synchronization of hyperexcitable pyramidal neurons

Keywords: 4-AP; 4-aminopyridine; AHP; Afterhyperpolarization; APV; dl-2-amino-5-phosphonopentanoic acid; BIC; Bicuculline methobromide; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; Cs-FP; Cesium-induced field potential; ImAHP; The Ca2+-dependent K+-current underlyin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Voltage-dependent calcium signaling in rat cerebellar unipolar brush cells

Keywords: unipolar brush cell; calcium; cerebellum; T-type calcium channels; L-type calcium channels; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate (AMPA); GABA; γ-amino-glutamic acid; Hepes; N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid; LJP; l

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Membrane estradiol signaling in the brain

Keywords: Estradiol receptor; mGluR; Caveolin; β-arrestin; Lordosis; Nociception; Neuroprogesterone

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Metabotropic Glutamate Receptors as Targets for Multipotential Treatment of Neurological Disorders

Keywords: Astrocytes; inflammation; metabotropic glutamate receptors; microglia; neuron; neuroprotection; 4CPG; (S)-4-carboxyphenylglycine; 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid; AIDA; 1-aminoindan-1, 5-dicarboxylic acid; ALS; amyotrophic lateral sclerosis; AM

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه