Keywords: پروتئین پریون; PrP; prion protein; PrPC; normal cellular isoform of PrP; PrPSc; abnormal misfolded isoform of PrP; CJD; Creutzfeldt Jakob disease; sCJD; sporadic CJD; dCJD; dura mater graft-associated CJD; p-dCJD; plaque-type dCJD; np-dCJD; non-plaque-type dCJD; 129M/M;
مقالات ISI پروتئین پریون (ترجمه نشده)
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Keywords: پروتئین پریون; Prion protein; POPG; Conformational conversion; Chicken prion protein; Murine prion protein;
Keywords: پروتئین پریون; Prion protein; Immunosensor; Prussian blue analogue; Electrochemical assay;
Keywords: پروتئین پریون; Prion protein; Small highly structured RNAs (shsRNAs); Pseudoknots; Poly A; Fluorescence anisotropy (r); Binding constant (Kd);
Keywords: پروتئین پریون; QRA; Abattoir; Prion protein; Scrapie; Specified risk materials;
Keywords: پروتئین پریون; Inherited prion disease; Creutzfeldt-Jakob disease; Prion protein; Rare gene variant; Novel gene variant interpretation;
Keywords: پروتئین پریون; Senescence; Copper; Prion protein; Oxidative stress; Fibroblasts;
Keywords: پروتئین پریون; Dendrimers; Dendrimer-protein composites; Enzymes; G4 dendrimer; fourth generation denrimer; PrP; prion protein; LDH; lactate dehydrogenase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase;
Keywords: پروتئین پریون; Aβ; amyloid-β; AD; Alzheimer's disease; Ahx; aminohexanoic linker; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; fAD; familial form of AD; GPI; glycophosphatidylinositol; HBSS; Hank's balanced salt solution; HFIP; hexafluoro-2-propanol; LDH; lacta
Keywords: پروتئین پریون; Aβ; amyloid β peptide; AD; Alzheimerʹs Disease; ALS; amyotrophic lateral sclerosis; Amb; Amphotericin B; BBB; blood-brain barrier; CJD; Creutzfeld Jakob disease; CSF; cerebral spinal fluid; DCS; D-Cycloserine; DOX; Doxorubicin; GA; Geldanamycin; GAPDH;
Keywords: پروتئین پریون; Prion protein; Protein misfolding; Prion disease; Alzheimer's disease; Signaling pathways; Calcium;
Inhibition of amyloid peptide fibril formation by gold-sulfur complexes
Keywords: پروتئین پریون; PrP; prion protein; hIAPP; human islet amyloid polypeptide; Aβ; amyloid-β protein; T2DM; type 2 diabetes mellitus; His; histidine; Met; methionine; DDTC; diethyl dithiocarbamate; PDT; pyrrolidine dithiocarbamate; DMSO; dimethyl sulphoxide; ThT; thioflav
Keywords: پروتئین پریون; α-syn; α-synuclein; Aβ; β-amyloid; AD; Alzheimer's disease; ADAMs; a disintegrin and metalloproteinases; ALS; amyotrophic lateral sclerosis; BSE; bovine spongiform encephalopathy; CJD; Creutzfeldt-Jakob disease; CNS; central nervous system; CSF; cer
Keywords: پروتئین پریون; Prion protein; Ordered mesoporous carbon; Host-guest interaction; Exonuclease III; Aptasensor;
Keywords: پروتئین پریون; Enfermedades priónicas; Manifestaciones neurológicas; Manifestaciones psiquiátricas; ProteÃna priónica; Prion deseases; Neurological manifestations; Psychiatric manifestations; Prion protein;
Keywords: پروتئین پریون; Prion protein; Prion diseases; Amyloid fibrils; Deformed templating; Synthetic prions; Protein misfolding cyclic amplification;
Keywords: پروتئین پریون; Field effect transistor; Thiamine; Blood serum; Prion protein; Early diagnosis; Metal ion;
Keywords: پروتئین پریون; Prion protein; Immunization; Salmonella vaccine strain; Bovine spongiform encephalopathy; Chronic wasting disease; White-tailed deer; Mucosal vaccination;
Keywords: پروتئین پریون; AD; Alzheimer's disease; CGT; UDP-galactose ceramide galactosyltransferase; CNS; central nervous system; CST; cerebroside sulfotransferase; GalCer; galactosylceramide; GlcCer; glucosylceramide; GCS; glucosylceramide synthase; GPI; glycosylphosphatidylinos
Keywords: پروتئین پریون; Aβ; amyloid-β peptide; AD; Alzheimer's disease; AFM; atomic force microscopy; ALS; amyotrophic lateral sclerosis; dpi; days post injection; HuPrP; human PrPC; HX-MS; hydrogen/deuterium exchange measured using mass spectrometry; LBs; Lewy bodies; PD; Par
Keywords: پروتئین پریون; Variable domain of heavy-chain antibody; Inhibition of protein misfolding and aggregation; Protein misfolding diseases; Amyloidoses; VHH; Nanobody; Ab; antibody; Aβ; amyloid β-peptide; AD; Alzheimer's disease; ANS; anilino naphthalene-sulfonic acid; AP;
Keywords: پروتئین پریون; AC; adenylyl cyclases; AD; Alzheimer's disease; AJ; adherent junctions; AMPAR; alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor; APC; antigen presenting cell; APP; amyloid precursor protein; Aβ; amyloid beta peptide; CAM; cellular adhesion
Keywords: پروتئین پریون; Aggregation; Color complementary; Prion protein; Quantum dots; Visual detection;
Keywords: پروتئین پریون; KA; kainic acid; i.p.; intraperitoneally; PrP; prion protein; RML; Rocky Mountain Laboratories; prion; kainic acid; seizures; Prnp; flanking genes; knockout mice;
Keywords: پروتئین پریون; PrP; prion protein; MB; methylene blue; wt-OvPrP; ovine recombinant wild-type full-length PrP (23-234); ÎOvPrP; ovine recombinant truncated PrP (103-234); MoPrP; murine recombinant full-length PrP (23-231); wt-HuPrP; wild-type human recombinant ful
Keywords: پروتئین پریون; H1, H2, H3; helices 1, 2, and 3; β1, β2; beta sheets 1 and 2; CBDPS; CyanurBiotinDiPropionylSuccinimide; PrPC; native (non-infectious) prion protein; PrPβ; β-oligomeric form of the prion protein; BS3; bis(sulfosuccinimidyl) suberate; EDC; 1-ethyl-3-[3
Keywords: پروتئین پریون; AA; ascorbic acid; BSE; Bovine spongiform encephalopathies; B3LYP; Becke 3 parameter Lee Yang Parr; BP86; Becke Perdew86; CD; Circular dichroism; CJD; Creutzfeldt-Jakob disease; CPMD; Car-Parrinello molecular dynamics; DFT; Density functional theory;
Keywords: پروتئین پریون; Prion protein; Ciliary epithelium; Cornea; Aqueous humor; Iron; β-cleavage;
Expression of recombinant human lysozyme in bacterial artificial chromosome transgenic mice promotes the growth of Bifidobacterium and inhibits the growth of Salmonella in the intestine
Keywords: پروتئین پریون; BAC; bacterial artificial chromosome; CPSF6; cleavage and polyadenylation specific factor 6; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; hLF; human lactoferrin; hLZ; human lysozyme; LB; lysogeny broth; PRNP;
D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals
Keywords: پروتئین پریون; Prion protein; Neurotoxicity; Susceptibility; Drosophila; Transgenics; Amino acid substitution; α3; (helix 3); Ca; (Canis, dog PrP); EqPrP; (Equus, horse PrP); PrP; (Prion protein); RaPrP; (rabbit PrP); sodium dodecyl sulfate-polyacrylamide gel electroph
Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains
Keywords: پروتئین پریون; ADAM23; a disintegrin and metalloprotease protein 23; CNS; central nervous system; conA; concanavalin A-Sepharose; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; PrPc; cellular prion protein; TNF; tumor necrosis factor; WGA; wheat germ a
Residue-specific mobility changes in soluble oligomers of the prion protein define regions involved in aggregation
Keywords: پروتئین پریون; Prion protein; Protein misfolding; Beta oligomer; Solution NMR; PrPSc; infectious particle of misfolded prion protein; PrP; prion protein; PrPc; cellular prion protein; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; CJD; Creutzfeldt
Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner
Keywords: پروتئین پریون; 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul
Quick and sensitive SPR detection of prion disease-associated isoform (PrPSc) based on its self-assembling behavior on bare gold film and specific interactions with aptamer-graphene oxide (AGO)
Keywords: پروتئین پریون; Surface plasmon resonance; Prion protein; Aptamer-graphene oxid; Sandwich; Self-assembling;
Omics analysis of mouse brain models of human diseases
Keywords: پروتئین پریون; Adam23; ADAM metallopeptidase domain 23; Alcam; activated leukocyte cell adhesion molecule; Apoe; apolipoprotein E; Atp5l; ATP synthase, HÂ + transporting, mitochondrial Fo complex subunit G; Cct8; chaperonin containing TCP1 subunit 8; Cd82; CD82 molecule
Cytotoxicity of prion protein-derived cell-penetrating peptides is modulated by pH but independent of amyloid formation
Keywords: پروتئین پریون; Aggregation; Amyloid; Cell-penetrating peptides; Cytotoxicity; Membrane perturbation; Prion protein;
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Keywords: پروتئین پریون; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;
Conversion of protein net charge via chemical modification for highly sensitive prion detection using field effect transistor (FET) biosensor
Keywords: پروتئین پریون; Field effect transistor; Biosensor; Prion protein; Signal amplification; Chemical modification; Protein charge;
Bacoside-A, an anti-amyloid natural substance, inhibits membrane disruption by the amyloidogenic determinant of prion protein through accelerating fibril formation
Keywords: پروتئین پریون; Bacoside; Prion protein; PrP(106-126); Amyloid peptides; Amyloid fibrils; Membrane interactions;
Prion pathogenesis is unaltered following down-regulation of SIGN-R1
Keywords: پروتئین پریون; CNS; central nervous system; FDC; follicular dendritic cell; IHC; immunohistochemistry; IV; intravenous; MARCO; macrophage receptor with collagenous structure; MZ; splenic marginal zone; PET.; paraffin-embedded tissue; PK; proteinase K; PrP; prion protein
Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease
Keywords: پروتئین پریون; APP; amyloid precursor protein; APPsi; APP with Swedish and Indiana mutations; sAPP; soluble N-terminal fragment of APP; CaMKIIα; calcium-calmodulin-dependent kinase II α; CTF; C-terminal fragment of APP; DG; dental gyrus of the hippocampus; FL-APP; ful
Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease
Keywords: پروتئین پریون; PrPC; membrane-anchored cellular prion protein; rPrP; recombinant human prion protein; Aβ; amyloid β; GPI; glycosylphosphatidylinositol; LTP; long-term potentiation; LDH; lactate dehydrogenase; fEPSPs; field evoked postsynaptic potentials; aCSF; artific
Pathogenic prion protein fragment (PrP106-126) promotes human immunodeficiency virus type-1 infection in peripheral blood monocyte-derived macrophages
Keywords: پروتئین پریون; Blood; HIV-1; Prion protein; Peripheral blood monocytes; Macrophages;
Membrane-mediated amyloid formation of PrP 106-126: A kinetic study
Keywords: پروتئین پریون; Prion protein; Lipid extracting effect; Neurodegenerative diseases; Amyloidal peptides; Circular dichroism; Giant unilamellar vesicles;
H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis
Keywords: پروتئین پریون; 2'-7'-DCF; 2'-7'-dichlorodihydrofluorescein; AβP; β-amiloid protein; BCA; bicinchoninic acid; CM-H2CFDA, 5-(and-6)-carboxy-2'; 7'dichlorofluorescein; DCDR; drop coating deposition Raman; EMSC; extended multiplicative signal correction; FHC; ferr
Cavitation during the protein misfolding cyclic amplification (PMCA) method - The trigger for de novo prion generation?
Keywords: پروتئین پریون; Prion; de novo; PMCA; Sonication; Cavitation; Free radical; PrP; prion protein; PrPres; protease-resistant isoform of PrP; PrPSc; protease-resistant, infectious isoform of PrP; rPrP; bacterially expressed recombinant PrP; PMCA; protein misfolding cyclic a
Prion protein functions as a ferrireductase partner for ZIP14 and DMT1
Keywords: پروتئین پریون; Dcytb; duodenal cytochrome b; DMT1; divalent metal transporter-1; FAC; ferric ammonium citrate; FR; ferrireductase; GFP; Green-fluorescent protein; ip; intraperitoneal; LIP; labile iron pool; NTBI; non-transferrin-bound iron; PrPC; prion protein; SDS-PAGE
Stabilization of microtubular cytoskeleton protects neurons from toxicity of N-terminal fragment of cytosolic prion protein
Keywords: پروتئین پریون; CtmPrP; transmembrane form of prion protein with the C-terminus residing in the lumen of endoplasmic reticulum; cytoPrP; cytosolic prion protein; ER; endoplasmic reticulum; GPI; glycosylphosphatidylinositol; GSK-3; glycogen synthase kinase 3; HBSS; Hank's
Novel N-terminal domain mutation in prion protein detected in 2 patients diagnosed with frontotemporal lobar degeneration syndrome
Keywords: پروتئین پریون; Frontotemporal dementia; Prion protein; P39L mutation; N-terminal domain;
Low expression level of OB-Rb results from constitutive translocational attenuation attributable to a less efficient signal sequence
Keywords: پروتئین پریون; VCAM-1; vascular endotherial cell adhesion molecule-1; PrP; prion protein; Prl; prolactin; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SRP; signal recognition particle; Dox; doxycycline; TMD; transmembrane domain; PK; protei