Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities
Keywords: RNA موی سر کوتاه; Nek2 inhibitors; Imidazo[1,2-a]pyridine; Antitumor activity; Selectivity; Nek2; NIMA-related kinase 2; Nlp; ninein-like protein; SAC; spindle assembly checkpoint; Mad1/2; mitotic arrest deficient 1/2; Hec1; highly expressed in cancer 1; CIN; chromosome in