Keywords: Ectopic lymphoid tissue; immunoglobulin; lymphoid aggregate; lymphorganogenesis; AID; Activation-induced cytidine deaminase; BAFF; B cell-activating factor of the TNF family; Bcl; B-cell lymphoma; CD21L; CD21 ligand; CRSsNP; Chronic rhinosinusitis witho
مقالات ISI (ترجمه نشده)
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Keywords: ADA; anti-drug antibodies; AMPK; 5â² adenosine monophosphate-activated protein kinase; aHUS; atypical hemolytic uremic syndrome; AMD; age-related macular degeneration; APC; antigen presenting cells; AT; anaphylatoxin; BTK; Bruton's tyrosine kinase; C1q
Keywords: ADP/ATP; adenosine di/tri phosphate; ApL; antiphospholipid; BTG; beta-thrombomodulin; COX; cycloâoxygenase; CVD; cardiovascular disease; DAMP; damage-associated molecular patterns; EC; endothelial cells; ECM; extracellular matrix; ET-1; endothelin-1; HC
Keywords: βCD; β-cyclodextrin; CD; cyclodextrins; CHO; cholesterol; Î; chemical shifts in 1H NMR; Îδ; induced chances in the 1H NMR chemical shifts; D/L; molar ratio of drug over the total lipid concentration; DCL; drug-in- cyclodextrin-in-liposome; DRV; dried
Keywords: SD IIV; standard dose inactivated influenza vaccine; HD IIV; high dose inactivated influenza vaccine; pTfh; peripheral T follicular helper cell; Influenza vaccine; High dose influenza vaccine; T follicular helper cells; Tfh; viSNE;
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: Immunotherapy; mechanisms; allergic rhinitis; allergic asthma; long-term tolerance; T cells; B cells; type 2 innate lymphoid cells; IgE-FAB; biomarkers; Breg; Regulatory B; C1Q; Component 1Q; CRTH2; Chemoattractant receptor-homologous molecule expressed
Keywords: Immunology; primary immunodeficiency; whole-exome sequencing; hematopoietic stem cell transplantation; common variable immunodeficiency; severe combined immunodeficiency; hyper-IgE syndrome; AIP1; Actin-interacting protein 1; APDS; Activated PI3Kδ syndro
Keywords: ILC2; iTr35; Tfh; Th1; Th2; Th22; CD; cluster of differentiation; CXCR5; CXC chemokine receptor 5; EBI3; Epstein-Barr virus-induced gene 3; FoxP3; forkhead box P3; IFN; interferon; ILC2; type 2 innate lymphoid cell; iTr35; IL-35-generated regulatory TÂ ce
Keywords: AMPK; adenosine monophosphate-activated protein kinase; ASD; autism spectrum disorder; BBB; blood-brain barrier; CVD; cardiovascular disease; CDI; Clostridium difficile infection; CD; Crohn's disease; DSS; dextran sulphate sodium; eCB; endocannabinoid; Fi
Keywords: NALT; nasal-associated lymphoid tissue; SHS; second-hand smoke; ETS; environmental tobacco smoke; TLRs; toll like receptors; ENT; ear nose throat; AMC; adenoidal mononuclear cells; Bregs; B regulatory cells; Tfh; T follicular helper cells; Passive smoke;
Keywords: humoral immunity; vaccination; regulatory T cells; Tfr; Tfh; germinal center
Keywords: CD; cyclodextrin; CHO; cholesterol; CLSM; confocal laser scanning microscopy; Co-E; co-evaporation method; CPAP; complex preparation in aqueous phase; Crysmeb; partially methylated crystallized-β-CD; DCL; drug-in-CD-in-liposome; Dimeb; 2,6-dimethyl-β-CD
Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
Non-obese type 2 diabetes patients present intestinal B cell dysregulations associated with hyperactive intestinal Tfh cells
Keywords: CD4+CXCR5+T cells; B cell; Tfh; Type 2 diabetes;
Circulating regulatory Tfh cells are enriched in patients with chronic hepatitis B infection and induce the differentiation of regulatory B cells
Keywords: HBV; Tfh; CXCR5; B cell; Breg;
A novel mouse model for tracking the fate of CXCR5-expressing T cells
Keywords: Follicular helper T cells; CXCR5; Memory T cells; Humoral immunity; GC; Germinal center; Tfh; Follicular helper T; OVA; Ovalbumin; CXC-R5; C-X-C chemokine receptor type 5; CCR7; C-C chemokine receptor type 7; ICOS; Inducible costimulator; PD-1; Programmed
Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases
Keywords: aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd
Monitoring the efficacy of infant hepatitis B vaccination and revaccination in 0- to 8-year-old children: Protective anti-HBs levels and cellular immune responses
Keywords: Hepatitis B virus; Yeast-derived recombinant vaccine; Immunogenicity; Lymphocyte subsets; Vaccine failure; HBV; hepatitis B virus; HBIG; hepatitis B immunoglobulin; HBsAg; hepatitis B surface antigen; HBeAg; hepatitis B e antigen; anti-HBc; antibodies aga
Dual-route targeted vaccine protects efficiently against botulinum neurotoxin A complex
Keywords: BoNT; clostridium botulinum neurotoxin; DCpep; dendritic cell binding peptide; Hc; heavy chain of BoNT/A; CL; colon; MLN; mesenteric lymph node; SP; spleen; PLN; peripheral lymph node; GC; germinal center; Tfh; T follicular helper cells; Botulinum neuroto
Co-delivery of a CD4 T cell helper epitope via covalent liposome attachment with a surface-arrayed B cell target antigen fosters higher affinity antibody responses
Keywords: Antibody response; Subunit vaccine; T cell help; Liposome; Vaccine delivery; Helper peptide; LLPC; Long-lived plasma cell; sLACK; liposomes packaged with free LACK peptide; pLACK; liposomes packaged with palmitoylated LACK peptide; iLN; inguinal lymph nod
B cell phenotypes, signaling and their roles in secretion of antibodies in systemic lupus erythematosus
Keywords: B cells; Tfh; SLE; Phenotype; Kinase;
Epigenetic mechanisms regulating T-cell responses
Keywords: Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice
Keywords: Follicular T cells; IL-4; IgE; allergy; peanut; IL-1; IL-33; BAL; Bronchoalveolar lavage; CTX; Cholera toxin; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; IL-1RAcP; IL-1R-associated protein; IN;
23-valent pneumococcal polysaccharide vaccine elicits hierarchical antibody and cellular responses in healthy and tuberculosis-cured elderly, and HIV-1-infected subjects
Keywords: PPV23; OPA; TB-cured elderly; HIV infection; PD; Pneumococcal disease; PPV23; 23-valent pneumococcal polysaccharide vaccine; HIV; human immunodeficiency virus; Mtb; Mycobacterium tuberculosis; IRB; Institutional Review Board; IBC; Institutional Biosafety
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Evidence for an autoimmune disease
Keywords: AdR; adrenergic receptor; BAFF; B-lymphocyte activating factor; dUTPase; deoxyuridine 5â²-triphosphate nucleotidohydrolase; EBV; Epstein-Barr virus; FM; fibromyalgia; 5-HT; 5-hydroxytryptanime; HHV; human herpes virus; IFNγ; interferon gamma; KIR; kille
The TH1 phenotype of follicular helper T cells indicates an IFN-γ-associated immune dysregulation in patients with CD21low common variable immunodeficiency
Keywords: Follicular helper T cells; common variable immunodeficiency; IFN-γ; germinal center; CD21low B cells; T-bet; CT; Computed tomography; cTFH; Circulating follicular T helper; CVID; Common variable immunodeficiency; CVIDc; Complex common variable immunodefi
Emerging roles of microRNAs in the metabolic control of immune cells
Keywords: Non-coding RNAs; Immunometabolism; T cells; Macrophages; Metabolic reprogramming; ATP; adenosine triphosphate; TCA; tricarboxylic acid cycle; PPP; pentose phosphate pathway; FAO; fatty acid oxidation; PEP; phosphoenolpyruvate; α-KG; alpha-ketoglutarate;
The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy
Keywords: αβ; alpha beta; ADCC; antibody-dependent cellular cytotoxicity; APC; antigen-presenting cell; BrHPP; bromohydrin pyrophosphate; BTLA; B and T lymphocyte attenuator; CAR; chimeric antigen receptor; DC; dendritic cell; γc; common gamma; γδ; gamma delta
Optimizing conventional DMARD therapy for Sjögren's syndrome
Keywords: 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma
Transfer of gene-corrected T cells corrects humoral and cytotoxic defects in patients with X-linked lymphoproliferative disease
Keywords: X-linked lymphoproliferative disease; T-cell gene therapy; follicular helper T cells; T-cell cytotoxicity; BV; Brilliant Violet; CTL; Cytotoxic T lymphocyte; HLH; Hemophagocytic lymphohistiocytosis; HSCT; Hematopoietic stem cell transplantation; HVS; Herp
Induction of plasmablasts by follicular helper T cell-CXCL13 axis upon occurrence of herpes zoster
Keywords: Herpes zoster; Plasmablast; Follicular helper T cell; CXCL13; Varicella zoster virus; APC; Allophycocyanin; CBA; Cytometric bead array; cTfh; Circulating T follicular helper; DENV; Dengue virus; ELISA; Enzyme-linked immunosorbent assay; FITC; Fluorescein
Cytokines as therapeutic targets in primary Sjögren syndrome
Keywords: APC; antigen-presenting cells; APRIL; a proliferation-inducing ligand; Auto-Ab; autoantibodies; BAFF; B-cell activating factor; BCR; B-cell receptor; Bm; mature B cell; BR3; B-cell activating factor receptor 3; DC; dendritic cell; FDC; follicular dendriti
Circulating CD4+ CXCR5+ T cells contribute to proinflammatory responses in multiple ways in coronary artery disease
Keywords: CD4+Â CXCR5+ T cell; Coronary artery disease; Tfh;
Original articleImmune characteristics study of AG490, a signal pathway inhibitor, in EAE model mice
Keywords: Tfh; EAE; IL-21; AG490; Model mice;
Achaete-scute complex homologue 2 accelerates the development of Sjögren's syndrome-like disease in the NOD/ShiLtJ mouse
Keywords: SS; Sjögren's syndrome; Ascl2; achaete-scute complex homologue 2; TFH; Follicular helper T cell; CXCR; C-X-C chemokine receptor; IL; interleukin; TNF; tumor necrosis factor; PD-1; programmed cell death 1; ICOS; inducible T-cell costimulator; BAFF; B-ce
ONX-0914, a selective inhibitor of immunoproteasome, ameliorates experimental autoimmune myasthenia gravis by modulating humoral response
Keywords: EAMG; experimental autoimmune myasthenia gravis; MG; myasthenia gravis; LMP7; low-molecular mass polypeptide-7; Tfh; follicular helper T cells; MNC; mononuclear cell; ONX-0914; Immunoproteasome; Experimental autoimmune myasthenia gravis; Humoral immunity;
Review articleDirect control of B cells by Tregs: An opportunity for long-term modulation of the humoral response
Keywords: Tregs; regulatory T cells; IPEX; Immunodysregulation Polyendocrinopathy Enteropathy X-linked syndrome; Th; T helper cells; APCs; Antigen Presenting Cells; TFR; T follicular regulatory cells; TFH; T follicular helper cells; SLE; Systemic Lupus Erythematosu
Rapid de novo generation of antigen specific human B cells with expression of Blimpâ1 and AID by in vitro immunization
Keywords: LLME; L-leucyl-L-leucine methyl ester; PBMCs; Peripheral blood mononuclear cells; Tfh; T follicular helper; ICOS; Inducible co-stimulator; DCs; Dendritic cells; BCL-6; B cell lymphoma 6; FBS; Fetal bovine serum; KLH; Keyhole limpet hemocyanin; MFI; Mean f
Beta2 integrins are required for follicular helper T cell differentiation in humans
Keywords: LAD-1; CD18 deficiency; Beta2 integrins; CD18; Follicular helper T cells (Tfh); Follicular regulatory T cells (Tfr); LAD-1; leukocyte adhesion deficiency syndrome type 1; Tfh; follicular helper T cells; Tfr; follicular regulatory T cells; Tr; regulatory T
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Keywords: STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration
Comparison of the physical characteristics of monodisperse non-ionic surfactant vesicles (NISV) prepared using different manufacturing methods
Keywords: NISV; non-ionic surfactant vesicles; TFH; thin-film hydration; PBS; phosphate buffered saline; MPG; monopalmitin glycerol; Chol; cholesterol; DCP; dicetyl phosphate; AFM; atomic force microscope; PDI; polydispersity index; ZP; zeta potential; FRR; flow ra
Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis
Keywords: PDCD1; Immune Regulation; Response To Treatment; Liver Disease; BAFF; B-cell-activating factor of the tumor necrosis factor family; BR3; B-lymphocyte stimulator receptor 3; CV; cryoglobulinemia vasculitis; DAA; direct-acting antiviral; EOT; end of treat
Critical Role for Skin-Derived Migratory DCs and Langerhans Cells in TFH and GC Responses after Intradermal Immunization
Keywords: DC; dendritic cell; dDC; dermal dendritic cell; DLN; draining lymph node; DT; diphtheria toxin; EC; ear cut; GC; germinal center; ID; intradermal; LC; Langerhans cell; LN; lymph node; NP; poly-lactic acid nanoparticle; PBS; phosphate buffered saline; PLA;
Pregnancy favors the expansion of circulating functional follicular helper T Cells
Keywords: Bcl-6; transcription factor B cell lymphoma-6; CMV; cytomegalovirus; E2-17β; estradiol; ELISA; Enzyme-linked immunosorbent assay; GC; germinal center; HbsAg; hepatitis B superficial antigen; HBV; hepatitis B virus; HIV; Human immunodeficiency virus; IC
Pivotal Role of Lesional and Perilesional T/B Lymphocytes in Pemphigus Pathogenesis
Keywords: BP; bullous pemphigoid; ELISPOT; enzyme-linked immunospot technique; PV; pemphigus vulgaris; Tfh; follicular helper T cell; Th; T helper; TLO; tertiary lymphoid organ;
CD11c+ T-bet+ memory B cells: Immune maintenance during chronic infection and inflammation?
Keywords: ABCs; Age-related B cells; AID; activation-induced cytidine deaminase; BCR; B cell receptor; DT; diphtheria toxin; EMLA; E. muris-like agent; FcR; Fc receptor; GC; germinal center; HCl; hairy cell leukemia; IOE; Ixodes ovatus ehrlichia; LPS; lipopolysacch
Human regulatory B cells control the TFH cell response
Keywords: Regulatory B cells; follicular T helper cells; IL-12; IL-21; antibody production; humoral immune response; Bcl-6; B-cell lymphoma 6; Breg; Regulatory B; DC; Dendritic cell; Foxp3; Forkhead box P3; GC; Germinal center; ICAM; Intercellular adhesion molecule