Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice

Inducible and selective ablation of MCs or basophils in non-c-kit mutant mice can significantly reduce PIA, but partial responses to peanut can still be observed in the virtual absence of both cell types. The neutrophilia in KitW-sh/W-sh mice might influence the responses of these mice in this PIA model.