کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3198536 | 1201893 | 2012 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes
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کلمات کلیدی
PDGFRBPDGFRAHENCelPDGFRFGFRMDSMPNSystemic mastocytosis - استاتوسیتوز سیستمیکHER - اوHES - او هستWorld Health Organization - سازمان بهداشت جهانیHypereosinophilic syndrome - سندرم Hypereosinophilicmyelodysplastic syndrome - سندرم میلودیسپلاستیکCriteria - شاخصClassification - طبقه بندیChronic eosinophilic leukemia - لوسمی ائوزینوفیل مزمنbone marrow - مغز استخوانMyeloproliferative neoplasm - نئوپلاسم میلوپرولیفراتیوHypereosinophilia - هیپرئوسینوفیلیاplatelet-derived growth factor receptor β - پلاکت عامل گیرنده فاکتور رشد βWHO - کهplatelet-derived growth factor receptor α - گیرنده عامل فاکتور رشد فاکتور αplatelet-derived growth factor receptor - گیرنده عامل فاکتور رشد یافته پلاکتfibroblast growth factor receptor - گیرنده فاکتور رشد فیبروبلاست
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Eosinophilia is an important indicator of various neoplastic and nonneoplastic conditions. Depending on the underlying disease and mechanisms, eosinophil infiltration can lead to organ dysfunction, clinical symptoms, or both. During the past 2 decades, several different classifications of eosinophilic disorders and related syndromes have been proposed in various fields of medicine. Although criteria and definitions are, in part, overlapping, no global consensus has been presented to date. The Year 2011 Working Conference on Eosinophil Disorders and Syndromes was organized to update and refine the criteria and definitions for eosinophilic disorders and to merge prior classifications in a contemporary multidisciplinary schema. AÂ panel of experts from the fields of immunology, allergy, hematology, and pathology contributed to this project. The expert group agreed on unifying terminologies and criteria and a classification that delineates various forms of hypereosinophilia, including primary and secondary variants based on specific hematologic and immunologic conditions, and various forms of the hypereosinophilic syndrome. For patients in whom no underlying disease or hypereosinophilic syndrome is found, the term hypereosinophilia of undetermined significance is introduced. The proposed novel criteria, definitions, and terminologies should assist in daily practice, as well as in the preparation and conduct of clinical trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 130, Issue 3, September 2012, Pages 607-612.e9
Journal: Journal of Allergy and Clinical Immunology - Volume 130, Issue 3, September 2012, Pages 607-612.e9
نویسندگان
Peter MD, Amy D. MD, Hans-Peter MD, Florence MD, PhD, Jason MD, Peter F. MD, Andrzej MD, Georgia MD, Kristin M. MD, Michel PharmD, PhD, Joseph H. MD, Wolfgang R. MD, Karl MD, Peter MD, PhD, Torsten MD, Hans-Uwe MD, PhD, Andreas MD, Gerald J. MD,